Clinical trials: Behcet's Syndrome
Behcet Disease and Vascular Involvement
Vascular Affection in Behcet Disease
To measure the level of serum elafin in patients with behcet disease and to assess the correlation between serum elafin and vascular affection and their relation with disease activity
- Trial name
- NCT06280430
- Volunteers
- 90 people
- Sponsor
- Assiut University
Behcet Disease
Phase III Study in Refractory Behcet's Disease
The purpose of this pivotal trial is to evaluate subcutaneous (SQ) AIN457 as an adjunctive therapy to reduce the rate of exacerbations of posterior uveitis or panuveitis secondary to Behçet's disease during the 24 weeks of study…
- Trial name
- SHIELD (NCT00995709)
- Testing
- AIN457
- Where
- 49 sites in United States, Egypt and 15 more
- Volunteers
- 118 people
- Sponsor
- Novartis Pharmaceuticals
Behcet Disease, Behcet Disease and Vascular Involvement
Immunosuppressive Therapy Alone Versus Plus Oral Anticoagulation in the Treatment of VT Associated With Behcet's Disease
This study is a Phase III, multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial investigating the treatment of lower extremity venous thrombosis associated with Behçet's Disease.
- Conditions
- Behcet Disease, Behcet Disease and Vascular Involvement, Deep Venous Thromboses, Post Thrombotic Syndrome
- Trial name
- BETTER (NCT06925698)
- Testing
- Rivaroxaban plus immunosupression
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Marmara University
Behcet's Disease
The Role of Rosuvastatin on Vascular Involvement in Behçet's Disease
Behçet's Disease(BD) is a systemic inflammatory vasculitis, which affects all types and sizes of vessels. Statins display numerous effects often independent of the well-established lipid-lowering effects that may be of benefit in…
- Trial name
- NCT04328064
- Testing
- Rosuvastatin calcium 40mg
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Alexandria
Behçet's Disease
The Relationship Between Serum Levels of Angiogenin, bFGF, VEGF and Ocular Involvement in Patients With Behçet's Disease
Objectives: Behçet's disease (BD) is a systemic vasculitis. Since vascular endothelial dysfunction plays a prominent role in the pathogenesis of the disease, we considered angiogenic cytokines as an interesting target for…
- Trial name
- NCT01720628
- Testing
- serum levels of angiogenin, bFGF, VEGF
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Turkish Ophthalmology Society
Uveitis, Diabetic Retinopathy
Biomarkers of Common Eye Diseases
To identify biomarkers of common eye diseases based on single-cell sequencing technologies using PBMC samples. These diseases include uveitis, diabetic retinopathy, age-related macular degeneration and polypoid choroidal…
- Conditions
- Uveitis, Diabetic Retinopathy, Age-related Macular Degeneration, Polypoidal Choroidal Vasculopathy
- Trial name
- NCT04101604
- Testing
- Collection of blood samples
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Behçet Disease
Dusquetide for the Treatment of Behcet's Disease
This is a clinical study to see if dusquetide can treat flares of oral and genital ulcers caused by Behcet's Disease. Study participants will receive an infusion of dusquetide twice a week for 4 weeks (8 treatments total), with…
- Trial name
- NCT06386744
- Testing
- Dusquetide
- Where
- Turkey (Türkiye)
- Volunteers
- 8 people
- Sponsor
- Soligenix
Behçet Disease
Apremilast Pediatric Study in Children With Active Oral Ulcers Associated With Behçet's Disease
The aim of this study is to estimate the efficacy of apremilast compared to placebo in the treatment of oral ulcers in pediatric participants from 2 to < 18 years of age with oral ulcers associated with Behçet's disease (BD)…
- Trial name
- BEAN (NCT04528082)
- Testing
- Apremilast
- Where
- 27 sites in France, Greece and 6 more
- Volunteers
- 60 people
- Sponsor
- Amgen
Retinal Vasculitis, Behcet Syndrome
Evaluation of Macular Vascular Changes in Behcet's Disease Using Optical Coherence Tomography Angiography
Behcet's disease is an important cause of retinal vasculitis and vision loss in Egypt. Fluorescein angiography is the standard method of diagnosis of retinal vasculitis.
- Trial name
- NCT03264391
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Muckle Wells Syndrome, Autoinflammatory
A Pilot Study of XOMA 052 in Familial Cold Autoinflammatory Syndrome / Muckle-Wells Syndrome and Behcet's Disease
Background: Autoinflammatory diseases are illnesses that produce episodes of inflammation such as fever, rash, or joint swelling.
- Conditions
- Muckle Wells Syndrome, Autoinflammatory, Behcet's Disease
- Trial name
- NCT01211977
- Testing
- XOMA 052
- Where
- United States
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Behcet Syndrome, Behcet Disease
Topical Pentoxifylline Gel on Behcet's Disease Genital Ulcers
Behçet's Disease (BD) is a complex, chronic, relapsing, multi-system inflammatory disorder that is characterized by oral ulcers, genital ulcers in addition to ocular and skin symptoms.
- Trial name
- NCT04186559
- Testing
- Topical Pentoxifylline Gel (Vehicle +PTX)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Silk Road Therapies, Inc.
Autoimmune, Behcet Syndrome
Diode Laser Versus Topical Corticosteroids in Management of Oral Ulcers in Behcet's Disease
Laser therapy is increasingly showing promising results in dental field including oral ulcers.This trial will assess the usefulness of Diode Laser compared to corticosteroid on oral ulcers of patients diagnosed with Behcet's…
- Trial name
- BD (NCT03771768)
- Testing
- Diode laser 980nm&100 mWatt, Triamcinolone Acetonide
- Volunteers
- 38 people
- Sponsor
- Cairo University
Behcet's Disease With Multisystem Involvement
Association of Auditory Dysfunction With Retinal Ischemia in Behcet Disease
Auditory dysfunction is commonly detected in Behçet's disease (BD). Also, vestibular abnormalities as well as cochlear function affection have been found.
- Trial name
- NCT05999461
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ocular Behcet's Disease,, Non-Infectious Uveitis
Flucinolone Acetonide Implant for Treating Refractory Ocular Behcet's Disease
Objectives: To describe the safety and efficacy of intravitreal flucinolone acetonide implants in the management of patients having refractory ocular Behcet's disease Hypothesis: A descriptive observational study Study design: A…
- Conditions
- Ocular Behcet's Disease,, Non-Infectious Uveitis, Refractory Uveitis
- Trial name
- NCT00720928
- Testing
- flucinolone acetonide
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Asan Medical Center
Behçet Disease
Inactivity Behavior and Exercise Bariers in Patients With Behçet Disease
Behçet's Disease (BD) is a chronic, inflammatory, rheumatic disease that is characterized by mucocutaneous lesions. Promoting physical activity level is one of the major goals in the management of patients with rheumatic…
- Trial name
- NCT03837236
- Testing
- Study group
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Gazi University
Vasculitis, Systemic Vasculitis
Impact of Vasculitis on Employment and Income
The purpose of this study is to learn about the impact of vasculitis on employment and income in patients with different systemic vasculitides.
- Conditions
- Vasculitis, Systemic Vasculitis, Behcet's Disease, CNS Vasculitis
- Trial name
- NCT02476292
- Testing
- online questionnaire
- Where
- United States
- Volunteers
- 426 people
- Sponsor
- University of South Florida
Oral Ulcer, Behcet Syndrome
Uses of Tacrolimus in Behcet Disease
Background: oral ulceration is the earliest and commonest manifestation of Behcet's disease (BD). Minor aphthous like ulcers (<10 mm in diameter) are the most common type (85%); major or herpetiform ulcers are less frequent.
- Trial name
- NCT05032248
- Testing
- Tacrolimus ointment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University