Clinical trials: Benign Breast Tumors
Breast Neoplasms, Germline BRCA1 Gene Mutation
Prospective Study of MAstectomy With Reconstruction Including Robot Endoscopic Surgery
Robotic mastectomy and immediate reconstruction have been introduced in 2015. However, since robotic mastectomy is the latest surgical technique, there is a lack of studies prospectively comparing conventional mastectomy and…
- Conditions
- Breast Neoplasms, Germline BRCA1 Gene Mutation, Germline BRCA2 Gene Mutation, Benign Breast Disease
- Trial name
- MARRES (NCT04585074)
- Testing
- Robotic or endoscopic nipple sparing mastectomy, Conventional mastectomy (including nipple sparing mastectomy, skin sparing mastectomy)
- Where
- 18 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- Severance Hospital
Cardiovascular Disease, Diabetes
Robust Evaluation to Measure Improvements in Nonadherence From Low-cost Devices
The aim of this study is to determine whether adherence to oral maintenance medications differs for patients randomized to receive a RxTimerCap, a Take-N-Slide, a standard pillbox, or none of these devices, with the hypothesis…
- Conditions
- Cardiovascular Disease, Diabetes, Breast Cancer, Depression
- Trial name
- REMIND (NCT02015806)
- Testing
- RxTimerCap, Take-N-Slide, Pillbox
- Where
- United States
- Volunteers
- 53,480 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Pilot Study of the Effect of Duavee® on Benign Breast Tissue Proliferation
The purpose of this study is to learn whether daily use of Duavee® is accepted and tolerated by peri- and post-menopausal women at moderate risk for development of breast cancer.
- Trial name
- NCT02729701
- Testing
- Duavee
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Kansas Medical Center
Benign Breast Neoplasm
Clinical Application of Near-infrared Fluorescence Guided Localization on Breast Surgery in Benign Breast Neoplasm.
Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has been used for breast cancer surgery such as sentinel lymph node (SLN) mapping and breast cancer localization.
- Trial name
- NCT02172989
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- National Cancer Center, Korea
Breast Cancer
Women At Risk: The High Risk Breast Cancer Program
The purpose of this study is to increase understanding of women who are at high risk for developing breast cancer. Data from this group will be collected and entered into a registry.
- Trial name
- WAR (NCT01034891)
- Where
- 2 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- New York Presbyterian Hospital
Breast Cancer.
ICG Distribution Using NIF Imaging After IV Injection of ICG in Benign and Malignant Breast Cancer Tissue.
The purpose of this study is to determine if NIF fluoresent imaging is an effctive approch to detect the margine of the breast tumoral tissue.
- Trial name
- EC2075 (NCT01993576)
- Testing
- Indocyanine Green
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Jules Bordet Institute
Breast Cancer, Mass Cystic
Combined Digital X-ray and Ultrasound Technique for Improved Detection and Characterization of Breast Lesions
The study will evaluate and refine a breast screening and diagnosis device.
- Conditions
- Breast Cancer, Mass Cystic, Benign Mass
- Trial name
- NCT00721435
- Testing
- 3D Tomosynthesis and ultrasound imaging
- Where
- 2 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Breast Benign Tumor, Breast Malignant Tumor
Evaluating the Performance of AI in Evaluating Breast MRI Performed With Dose Reduction
The purpose of this study is to evaluate the ability of AI to correctly aid in characterization of benign and malignant lesions even when a low dose of gadolinium is administered.
- Trial name
- NCT04340180
- Testing
- Standard of Care (SOC) gadolinium Breast MRI, reduced 1/4 dose gadolinium Breast MRI with Artificial Intelligence (AI) to aid in evaluation.
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Breast Benign, Malignant Neoplasm of Breast
Low-field MRI for Breast Cancer Screening
This research study wants to learn more about improving the attainable image quality for ultra-low field MRI of the breast using new data acquisition methods(also called MRI pulse sequences) and image reconstruction algorithms.
- Conditions
- Breast Benign, Malignant Neoplasm of Breast, Breast Malignant Tumor
- Trial name
- NCT05486520
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pain, Postoperative, Mastectomy
Comparison of Pain Therapeutic Effects After Benign Mastectomy
With the incremental trend of benign breast tumor, the surgical process of mastectomy was proceeded too much every day, especially in the Maternal Health Care Hospital, but whether the investigators can find another way to…
- Trial name
- COPTEAM (NCT00519246)
- Testing
- Saline, Opioid, NSAID
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Nanjing Medical University
Breast Tumors
Evaluate the Use of the Magnetic Resonance Spectroscopy in Determining if the Breast Tumor is Benign or Malignant
Magnetic Resonance Spectroscopy (MRS) is a novel imaging technique for noninvasive probing of biochemical properties of tissue. While MRS does not generate images of tumor per se it allows biochemical spectroscopic data to be…
- Trial name
- NCT00639171
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Benign Breast Neoplasm, Ductal Breast Carcinoma In Situ
Study of Docosahexaenoic Acid (DHA) in Triple Negative Breast Cancer Survivors
This randomized phase II trial studies how well docosahexaenoic acid works in preventing recurrence in breast cancer survivors. Docosahexaenoic acid supplement may prevent recurrence in breast cancer survivors.
- Conditions
- Benign Breast Neoplasm, Ductal Breast Carcinoma In Situ, Invasive Breast Carcinoma, Lobular Breast Carcinoma In Situ
- Trial name
- NCT01849250
- Testing
- Docosahexaenoic Acid
- Where
- 4 sites in United States
- Volunteers
- 65 people
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer Female, Diagnoses Disease
Ultrasound-based Diagnostic Model for Differentiating Malignant Breast Lesion From Benign Lesion
This study proposed to construct an ultrasound-based diagnostic model for Differentiating Malignant Breast Lesion From Benign Lesion.
- Trial name
- NCT03080623
- Where
- 4 sites in China
- Volunteers
- 1,981 people
- Sponsor
- Peking University
Fibrocystic Disease of Breast, Breast Cancer
A Comparison of Breast Tomosynthesis Mammography and Conventional Breast Imaging in the Characterization of Breast Masses
The purpose of this study is to compare conventional breast imaging and diagnostic work-up (2 dimensional imaging) to digital breast tomosynthesis (3 dimensional imaging) in the appearance of non-calcified breast masses.
- Trial name
- NCT00826488
- Testing
- Digital Breast Tomosynthesis
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Washington University School of Medicine
Malignant Tumor of Breast, Benign Breast Lumps
Implantation of CEST and CESL MRI Methods for Detection of Breast Tumors
MRI is a well-established method in breast imaging. It gives excellent morphological information but does not reflect the metabolic activity leading to high proportion of false positive results.
- Conditions
- Malignant Tumor of Breast, Benign Breast Lumps, High-Risk Breast Cancer
- Trial name
- NCT05305937
- Testing
- MRI scan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Cancer Risk, Cancer Predisposition Syndrome
InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer
This research study is creating a way to collect and store specimens and information from participants who may be at an increased risk of developing cancer, or has been diagnosed with an early phase of a cancer or a family member…
- Conditions
- Cancer Risk, Cancer Predisposition Syndrome, Hereditary Cancer Prediction, Childhood Cancer Survivors
- Trial name
- NCT05463796
- Testing
- Samples
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer, Benign Breast Disease
Promoting Earlier Detection of Breast Cancer in Rwanda: Scaleup in the National Health Care System
This observational study evaluates scale-up of a breast cancer early detection program in Rwanda that was initially piloted in a single district.
- Trial name
- NCT04258085
- Testing
- Early diagnosis program combined with electronic medical record
- Where
- Rwanda
- Volunteers
- 17,379 people
- Sponsor
- Brigham and Women's Hospital
Breast Cancer
Pilot Clinical Evaluation of a Microwave Imaging System for Breast Cancer Detection
The trialed investigational medical imaging device is a low-power microwave breast imaging system for cancer screening purposes. It is an active device which uses non-ionizing radiation.
- Trial name
- NCT05757427
- Testing
- Wavelia #2
- Where
- Ireland
- Volunteers
- 73 people
- Sponsor
- MVG Industries SAS
Breast Neoplasms
Comparison of Sevoflurane and Isoflurane Anesthesia for Benign Breast Tumor Excision
Generally, benign breast tumors are excised under the local anesthesia. But such action was so invasive that every patient would experience the physiological and psychological stimuli unavoidably.
- Trial name
- CSIABTEC (NCT00575354)
- Testing
- Sevoflurane, Isoflurane
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Breast Cancer Detection, Dense Breast Parenchyma
Delphinus SoftVue™ ROC Reader Study
The purpose of this multi-reader, multi-case (MRMC) reader study is to evaluate reader performance when SoftVue™ automated breast ultrasound and screening mammography are combined, compared to screening mammography alone, in…
- Conditions
- Breast Cancer Detection, Dense Breast Parenchyma, Benign Breast Findings, Normal Breast Screening
- Trial name
- DMT SV RRS2 (NCT03972605)
- Testing
- Reading of Automated Breast Ultrasound in conjunction with Screening Mammography
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Delphinus Medical Technologies, Inc.