Clinical trials: Benign Essential Blepharospasm
Blepharospasm
A Mechanical Device for Blepharospasm
Idiopathic blepharospasm (IB) is a rare but well characterised adult onset focal dystonia that may cause severe visual disability.
- Trial name
- NCT03269123
- Testing
- Pressop 1
- Volunteers
- 58 people
- Sponsor
- Oxford University Hospitals NHS Trust
Blepharospasm
Comparison of Korean Botulinum Toxin Type A Versus Botox in the Treatment of Essential Blepharospasm
To compare the efficacy and safety of Korean botulinum toxin A (KbtxA, Pacific Pharmaceuticals, Korea) against Botox in the treatment of essential blepharospasm, we performed a double-blinded, randomized, comparative trial…
- Trial name
- NCT00682760
- Testing
- Korean Botulinum toxin type A (KbtxA) and Botox injection
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Pacific Pharmaceuticals
Benign Essential Blepharospasm
rTMS and Botulinum Toxin in Benign Essential Blepharospasm
Benign essential blepharospasm (BEB) is a functionally disabling focal dystonia. Botulinum neurotoxin (BoNT) therapy is suboptimal in many BEB patients.
- Trial name
- NCT02370875
- Testing
- Magstim RapidStim2
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Blepharospasm, Dystonia
Exploratory Study of Dipraglurant (ADX48621) for the Treatment of Patients With Blepharospasm
This study is designed to assess the safety and tolerability of dipraglurant in patients with blepharospasm (BSP) (randomized 1:1:1 to receive dipraglurant 50 mg, 100 mg or placebo) and explore the efficacy of 50 mg and 100 mg…
- Trial name
- NCT05027997
- Testing
- Dipraglurant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Addex Pharma S.A.
Cervical Dystonia, Primary, Blepharospasm
Analysis of Gait Before and After Botulinum Toxin Treatment in Patients With Focal Dystonia
Efficient gait requires effective postural control, both static and dynamic. Hence, postural disorders may affect gait. Yet, very little is known about the specific effects of focal postural disorders such as cervical dystonia…
- Trial name
- GAIT-TOX (NCT03938363)
- Testing
- Treadmill, Botulinum Toxin injection, Severity scale of the disease
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Dry Eye Syndromes, Meige Syndrome
Wumeiwan Jiawei Fang Use in Patients With Blepharospasm
To evaluate the efficacy and safety of Jing Fang Wu Mei Wan Jiawei Fang in the treatment of idiopathic blepharospasm using a clinical randomized controlled trial method.
- Conditions
- Dry Eye Syndromes, Meige Syndrome, Blepharospasm, Hyperactivity
- Trial name
- NCT05618470
- Testing
- Wumeiwan Jiawei Fang, botulinum toxin A
- Where
- China
- Volunteers
- 80 people
- Sponsor
- China Academy of Chinese Medical Sciences
Blepharospasm, Hemi Facial Spasm
An RCT of a Patient-initiated Treatment Service for BEB and HFS
Blepharospasm and hemifacial spasm are debilitating conditions which significantly impact on patient quality of life. Cyclical treatment with botulinum toxin injections offers temporary relief but the duration of treatment…
- Trial name
- NCT02577224
- Testing
- Patient-initiated treatment
- Where
- United Kingdom
- Volunteers
- 130 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Blepharospasm, Benign Essential
The Role of the Upper Colliculus in the Idiopathic Blepharospasm
This pilot study aims at investigating the role of superior colliculus in patients with idiopathic blepharospasm (BSP) de novo, compared to healthy subjects.
- Trial name
- COLL-BSP (NCT03903341)
- Testing
- fMRI
- Where
- France
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Blepharospasm
Comparison of Two Botulinum Type A Products in the Treatment of Blepharospasm
This pilot study estimates the treatment effects of two different types of botulinum toxin type A in the treatment of Blepharospasm.
- Trial name
- NCT00761592
- Testing
- Botulinum Toxin Type A 900kDa, Botulinum Toxin Type A 150kDa
- Where
- 3 sites in Germany
- Volunteers
- 65 people
- Sponsor
- Allergan
Benign Essential Blepharospasm, Hemifacial Spasm
Effects of DaxibotulinumtoxinA for Blepharospasm and Hemifacial Spasm
The goal of this clinical trial is to test the effects of DaxibotulinumtoxinA-Lanm (Daxxify) in patients with benign essential blepharospasms (BEB) and hemifacial spasms (HFS). The main questions to answer: 1.
- Trial name
- NCT06195241
- Testing
- DaxibotulinumtoxinA
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Montefiore Medical Center
Essential Blepharospasm
Clinical Study to Evaluate the Efficacy and Safety of Neuronox and Botox With Essential Blepharospasm
This clinical study evaluates the efficacy and safety of Neuronox compared with Botox in adults with essential blepharospasm.
- Trial name
- NCT03216473
- Testing
- Neuronox, Botox
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medy-Tox
Blepharospasm
Botulinum Toxin Relieves Anxiety, Depression and Sleep Disorderes in Patients With Blepharospasm
Blepharospasm (BSP) is a chronic, idiopathic, recurrent and progressive disease, which mostly occurs in both eyes. It is mainly manifested as involuntary spasm of muscles around the eyes, leading to uncontrollable narrowing or…
- Trial name
- NCT04939909
- Testing
- Botulinum toxin type A
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine