Clinical trials: Benign Hyperplasia of Prostate
BPH (Benign Prostatic Hyperplasia)
Real-Time (TRUS) Guidance in Endoscopic Treatment of BPH
The study aims to evaluate the role of TRUS in improving the efficacy and safety of endoscopic enucleation of prostate and TURP.
- Trial name
- NCT06922968
- Testing
- TRUS-Guided TURP and enucleation, Standard TURP and enucleation
- Where
- Egypt
- Volunteers
- 114 people
- Sponsor
- Assiut University
Benign Prostatic Hyperplasia
GreenLight Laser Photoselective Vaporization of the Prostate vs Bipolar Transurethral Vaporization of the Prostate; RCT
With a growing body of knowledge on the promising advancements and recent clinical data of the third generations of the Greenlight PVP/XPS, it seems to be a real contender in the world of MIS.
- Trial name
- NCT02283684
- Testing
- Greenlight laser PVP, Bipolar TUVP
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia (BPH)
Clinical Study on Prostate Thermal Vapor Ablation Guided by MRI/TRUS Fusion Imaging
This study evaluates a new imaging-guided approach for treating benign prostatic hyperplasia (BPH), also known as enlarged prostate. BPH is a common condition in older men that can cause bothersome urinary symptoms.
- Trial name
- NCT06817733
- Testing
- Procedure/Surgery: MRI/TRUS Fusion-Guided Transurethral Water Vapor Thermal Therapy, Rezūm Water Vapor Thermal Therapy System with MRI/TRUS Fusion and Electromagnetic Navigation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Acute Urinary Retention, Benign Prostatic Hyperplasia
Tamsulosin Dose Escalation or Silodosin Switch Before Trial Without Catheter in BPH-Related Acute Urinary Retention
This randomized controlled trial will compare three medication strategies before trial without catheter in men with acute urinary retention due to benign prostatic hyperplasia who were already taking tamsulosin 0.4 mg once daily…
- Trial name
- NCT07650968
- Testing
- Tamsulosin 0.4 mg, Tamsulosin 0.8 mg, Silodosin 8 mg
- Where
- Egypt
- Volunteers
- 378 people
- Sponsor
- Beni-Suef University
Hematuria, Benign Prostatic Hyperplasia
RADA16 for Aquablation Day Case
This is a pilot proof of concept single-arm study using PuraStat following Aquablation procedure to assess reduction of hematuria to allow for same day discharge.
- Conditions
- Hematuria, Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
- Trial name
- RAD (NCT06948331)
- Testing
- PuraStat
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- NYU Langone Health
Benign Prostatic Hypertrophy
Dutasteride After Failure of Finasteride In the Management of Symptomatic Prostatic Enlargement/Hypertrophy (BPE/H)
The study is to determine the safety and efficacy of Dutasteride in patients who have failed Finasteride therapy for their symptomatic benign prostatic enlargement/ hypertrophy (BPE/H).
- Trial name
- NCT00382356
- Testing
- Dutasteride
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- North Florida/South Georgia Veterans Health System
Benign Prostatic Hyperplasia
Acute Hemostasis Following the Use of the AQUABEAM® System for the Treatment of Benign Prostatic Hyperplasia II
A single-arm prospective, interventional clinical trial to evaluate the safety and performance of obtaining hemostasis following prostate resection using the AQUABEAM for treatment of LUTS resulting from BPH.
- Trial name
- AHA II (NCT03125889)
- Testing
- AquaBeam System
- Where
- India
- Volunteers
- 11 people
- Sponsor
- PROCEPT BioRobotics
Benign Prostatic Hyperplasia
Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.
Many patients may face long-term urinary side effects following stereotactic body radiation therapy (SBRT), including increased urinary frequency, dysuria, and nocturia.
- Trial name
- NCT05148156
- Testing
- Urolift
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Overactive Bladder
A Phase 4 Study to Evaluate the Efficacy, Safety, and Tolerability of Mirabegron in Male Subjects With Overactive Bladder (OAB) Symptoms, While Taking the Alpha Blocker for Benign Prostatic Hypertrophy (BPH)
The primary objective of the study was to investigate the efficacy of mirabegron versus placebo in male patients with OAB symptoms while taking the alpha blocker, tamsulosin, for BPH.
- Trial name
- NCT02656173
- Testing
- Mirabegron, Tamsulosin
- Where
- 58 sites in Japan, South Korea
- Volunteers
- 568 people
- Sponsor
- Astellas Pharma Inc
Benign Prostatic Hyperplasia, Nocturia Associated With Nocturnal Polyuria
A Clinical Observation Study of a Chinese Patent Medicine Combined With Tamsulosin in Improving Sleep and Nocturia Symptoms After Enucleation of the Prostate
This study will test whether a traditional Chinese medicine called Lingze tablets, when added to the standard drug tamsulosin, can better improve sleep and nighttime urination problems in men after prostate surgery.
- Trial name
- NCT07357324
- Testing
- Tamsulosin Hydrochloride Sustained-Release Capsules, Lingze Tablets
- Where
- China
- Volunteers
- 136 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Prostatic Hyperplasia, Benign Prostatic Hyperplasia
Rezum I Pilot Study for Benign Prostatic Hyperplasia
Evaluate the safety and efficacy of the Rezum System for the treatment of BPH
- Conditions
- Prostatic Hyperplasia, Benign Prostatic Hyperplasia, Adenoma, Prostatic, Prostatic Adenoma
- Trial name
- Rezum Pilot (NCT02943070)
- Testing
- Rezum System
- Where
- 3 sites in Czechia, Dominican Republic and 1 more
- Volunteers
- 50 people
- Sponsor
- Boston Scientific Corporation
Benign Prostatic Hyperplasia
Saw Palmetto Extract in Benign Prostatic Hyperplasia
The purpose of this study is to test whether an extract of the saw palmetto plant is effective for relieving symptoms of Benign Prostatic Hyperplasia (BPH).
- Trial name
- NCT00037154
- Testing
- Saw Palmetto
- Where
- 2 sites in United States
- Volunteers
- 224 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
BPH (Benign Prostatic Hyperplasia)
HoLEP-ThuLEP - Comparing Lasers for BPH Surgery
Benign prostatic hyperplasia (BPH) is a very common condition in older men. As the prostate enlarges, it can press on the urethra and make urination difficult.
- Trial name
- HOT (NCT07565961)
- Testing
- Thulium Laser Enucleation of the Prostate (ThuLEP), Holmium Laser Enucleation of the Prostate (HoLEP)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Benign Prostatic Hyperplasia
Effectiveness and Safety of Silodosin in the Treatment of Benign Prostatic Hyperplasia
The purpose of this study is to confirm in a larger population in Europe the effectiveness and safety observed with silodosin in previous clinical trials.
- Trial name
- SiRE (NCT01757769)
- Testing
- Silodosin
- Where
- Italy
- Volunteers
- 1,036 people
- Sponsor
- RECORDATI GROUP
Benign Prostatic Hyperplasia
Study of Tadalafil Once-a-Day for 12 Weeks in Japanese Men With Benign Prostatic Hyperplasia Followed by an Open-Label Extension
This study is a randomized, double-blind, placebo-controlled, parallel-design to compare the efficacy and safety of tadalafil once-a-day dosing versus placebo for 12 weeks followed by an open-label extension to evaluate the…
- Trial name
- NCT00783094
- Testing
- Tadalafil 2.5 mg, Tadalafil 5 mg
- Where
- 6 sites in Japan
- Volunteers
- 422 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia
HoLEP vs BipolEP in Management of BPH Patients With Large Prostates
This is a non-inferiority prospective randomized comparative clinical trial aiming to prove the non-inferiority of bipolar enucleation of the prostate in comparison to holmium laser enucleation of the prostate in management of…
- Trial name
- NCT06759194
- Testing
- Holmium Laser Enucleation of the Prostate, Bipolar Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 98 people
- Sponsor
- Assiut University
Overactive Bladder, Urinary Urgency Incontinence
Sacral Neuromodulation for Male Overactive Bladder (MOAB)
To assess the post-market clinical outcomes of the Axonics SNM System for treatment of overactive bladder in male patients.
- Conditions
- Overactive Bladder, Urinary Urgency Incontinence, Benign Prostatic Hyperplasia, Prostate Cancer
- Trial name
- NCT06511141
- Testing
- Axonics SNM System
- Where
- 23 sites in United States
- Volunteers
- 150 people
- Sponsor
- Axonics, Inc.
Benign Prostatic Hyperplasia
A Prospective, Multicenter, Open-label Study of the Beacon Platform for Holmium Laser Enucleation of the Prostate (HoLEP)
Robotic assisted surgery for benign prostatic hyperplasia (BPH)
- Trial name
- NCT06668142
- Testing
- Beacon Platform
- Where
- 3 sites in Chile, New Zealand
- Volunteers
- 54 people
- Sponsor
- Andromeda Surgical
Benign Prostatic Hyperplasia
Transurethral Ventral Wall of Urethra-preserving Enucleation of Prostate
In this study, the investigators designed a randomized and double-blind prospective trial to evaluate the efficiency and safety of the investigators new approach-transurethral ventral wall of urethra-preserving enucleation of…
- Trial name
- NCT01073241
- Testing
- transurethral ventral wall of urethra-preserving enucleation of prostate, transurethral prostatic resection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
Benign Prostatic Hyperplasia
GreenLight XPS Laser System Retrospective Chart Review
The purpose of this study is to gain information on the safety, efficacy, and quality of life in subjects who have had the GreenLight XPS procedure.
- Trial name
- NCT02139969
- Testing
- GreenLight XPS Laser System
- Where
- 6 sites in United States, Canada
- Volunteers
- 956 people
- Sponsor
- Boston Scientific Corporation