Clinical trials: Benign Hyperplasia of Prostate
Benign Prostatic Hyperplasia
Randomized, Double-Blind, Vehicle-Controlled, Multicenter Safety and Efficacy Study of Intraprostatic PRX302 for LUTS BPH
The purpose of this study is to evaluate the safety and efficacy of a single treatment of PRX302 for the treatment of Benign Prostatic Hyperplasia (BPH) as compared to placebo.
- Trial name
- PLUS-1 (NCT01966614)
- Testing
- PRX302
- Where
- 76 sites in United States, Australia and 4 more
- Volunteers
- 479 people
- Sponsor
- Sophiris Bio Corp
Prostatic Diseases
Benign Prostatic Hyperplasia in Taiwan
Primary Objective: To assess the sexual function of Benign Prostatic Hyperplasia patients Secondary Objective: To evaluate the association between Lower Urinary Tract Symptoms severity and sexual disorders To compare the sexual…
- Trial name
- NCT00941343
- Testing
- Alfuzosin (XATRAL® - SL770499)
- Where
- Taiwan
- Volunteers
- 362 people
- Sponsor
- Sanofi
Prostate Hyperplasia
HoLEP Vs BPEP for Large Prostatic Adenoma
Benign prostatic hyperplasia (BPH) is one of the most common urinary disorders in elderly males. The symptoms of BPH include impaired physiological and functional well-being, which interferes with daily living.
- Trial name
- enucleation (NCT04275076)
- Testing
- Holmium laser enucleation of the prostate versus bipolar transurethral enucleation of the prostate in management of benign prostatic hyperplasia
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahmed Maher Gamil Ahmed Higazy
Benign Prostatic Hyperplasia
Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia
Aim of this study is to evaluate the effect of conducting self-management interventions on severity of lower urinary tract symptoms (LUTS) for patients with benign prostatic hyperplasia (BPH).
- Trial name
- NCT06051383
- Testing
- Self management
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Amna A. Desouky, MD
Prostate Hyperplasia
Comparative Study Between Rezum and Tamsulosin
the investigators aimed to compare the efficacy and safety of Rezūm therapy for the management of benign prostatic hyperplasia (BPH) with Tamsulosin.
- Trial name
- NCT07169773
- Testing
- Rezum, Tamsulosin
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- khaled Abdelsattar Gad Ibrahim
Benign Prostatic Hyperplasia
Patient-reported Pain and Symptom Relief During Three Months After Surgery for Benign Prostatic Hyperplasia
This is a prospective observational study in patients undergoing surgery for benign prostatic hyperplasia (BPH). The purpose of the study is to investigate in great detail patients' recovery after surgery for BPH regarding pain…
- Trial name
- NCT06852859
- Testing
- Transurethral resection of the prostate, Transurethral vaporization of the prostate, GreenLight laser enucleation of the prostate
- Where
- 3 sites in Sweden
- Volunteers
- 500 people
- Sponsor
- Sahlgrenska University Hospital
BPH
Explorative Study of Degarelix for Treatment of Benign Prostatic Hyperplasia.
This exploratory study will be conducted open label in a single investigational clinical unit. Altogether 52 patients with benign prostate hyperplasia (BPH) will be randomly assigned to receive 4 different treatments with…
- Trial name
- NCT00527488
- Testing
- Degarelix
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Ferring Pharmaceuticals
Benign Prostatic Hyperplasia
Phase 3 Study of Tadalafil Once-Daily in Asian Men With Benign Prostatic Hyperplasia (BPH)
This is a phase 3, randomized, double-blind, placebo-controlled, parallel-design, multinational study to evaluate the efficacy and safety of tadalafil once-a-day dosing for 12 weeks in Asian men with signs and symptoms of benign…
- Trial name
- NCT01460342
- Testing
- Tadalafil
- Where
- 17 sites in Japan, South Korea
- Volunteers
- 610 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia
A Clinical Trial to Evaluate the Safety and the Pharmacokinetics of AD-116 Compared to AD-1161 in Healthy Adult Male Volunteers
The study compare and evaluate the safety and pharmacokinetic characteristics between the administration of AD-116 and the administration of AD-1161 in healthy adult male volunteers
- Trial name
- NCT07103278
- Testing
- AD-116, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Benign Prostatic Hyperplasia
A Pumpkin Seed, Isoflavonoid and Cranberry Mix in LUTS/BPH
The aim is to assess the efficacy of a mix of Pumpkin Seed Extract, Soy Germ Isoflavonoids and Cranberry (Novex®) in the management of mild to moderate LUTS in BPH patients.
- Trial name
- NCT04146103
- Testing
- Novex
- Where
- Lebanon
- Volunteers
- 163 people
- Sponsor
- Saint-Joseph University
Prostatic Hypertrophy, Benign
Vardenafil in Greenlight(TM) Laser Surgery of Benign Prostate Hypertrophy
The greenlight laser has an absorption maximum which is exactly the same as for hemoglobin. In the presence of hemoglobin, its application causes vaporization of the tissue and this effect depends on the concentration of…
- Trial name
- NCT00461123
- Testing
- Vardenafil (Levitra, BAY38-9456)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Bayer
Benign Prostatic Hyperplasia
A Pilot Study Of The ALPFA Benign Prostatic Hyperplasia (BPH) Pulsed Field Ablation (PFA) System
The ALPFA Medical BPH Pilot Study is a prospective, open label, single arm pilot study to assess the use of the ALPFA BPH PFA System in the treatment of men over the age of 45 with obstructive urinary symptoms associated with…
- Trial name
- NCT06965582
- Testing
- ALPFA BPH PFA System
- Where
- 4 sites in Czechia, Italy and 1 more
- Volunteers
- 100 people
- Sponsor
- ALPFA Medical
Neoplasms, Prostate, Benign Prostatic Hyperplasia
Economic Analyses of the REDUCE Trial
The objective of this project is to conduct a retrospective economic analysis of the use of dutasteride for the prevention of prostate cancer based on data from the REDUCE clinical trial.
- Conditions
- Neoplasms, Prostate, Benign Prostatic Hyperplasia, Cancer
- Trial name
- NCT01337258
- Testing
- Dutasteride
- Volunteers
- 1 people
- Sponsor
- GlaxoSmithKline
Benign Prostatic Hyperplasia
Prostate Artery Embolization Compared to Holmium Laser Enucleation of the Prostate for Benign Prostatic Hyperplasia
The purpose of this study is to evaluate improvement of symptoms from benign prostatic hyperplasia (BPH) as assessed by the International Prostate Symptom Score (IPSS) for prostate artery embolization (PAE) with microspheres…
- Trial name
- NCT04236687
- Testing
- Holmium laser enucleation of the prostate, Artery embolization of the prostate
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Germans Trias i Pujol Hospital
Benign Prostatic Hyperplasia
An Observational Study of Dutasteride and Alpha-blocker Combination Therapy in Men With Symptomatic Benign Prostatic Hyperplasia and PSA Level Over 4 ng/mL
To analyze the change in International Prostate Symptom Score (IPSS) and serum prostate-specific antigen (PSA) level from baseline.
- Trial name
- NCT01351987
- Where
- Taiwan
- Volunteers
- 855 people
- Sponsor
- Taipei Medical University WanFang Hospital
Prostatic Hyperplasia
Benefits of Adherence to 5-alpha Reductase Inhibitor Treatment in Men With Enlarged Prostate: An Assessment of Medicare and Medicaid Patients Using the MarketScan Database
Adherence and length of treatment with a 5-alpha reductase inhibitor (5ARI) therapy may be associated with improved clinical outcomes for patients with enlarged prostates (EP) and lower health care related costs.
- Trial name
- NCT01376258
- Testing
- 5ARI
- Volunteers
- 28,903 people
- Sponsor
- GlaxoSmithKline
Impotence
Effectiveness and Safety of Viagra in Men With ED and LUTS Due to Benign Prostatic Hyperplasia (BPH)
The purpose of this study is to determine whether Viagra is effective in treating erectile dysfunction and lower urinary tract symptoms in men affected by both conditions.
- Trial name
- NCT00143221
- Testing
- Viagra
- Volunteers
- 350 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Benign Prostatic Hyperplasia
Comparison of Functional Outcomes of Ejaculation-preserving Partial Trans Urethral Resection of the Prostate With Complete Trans Urethral Resection of the Prostate for Benign Prostatic Obstruction
It has been demonstrated that sexual activity was common in the majority of men over 50 years old and was an important component of overall quality of life (QoL).
- Trial name
- PARTURP (NCT05574244)
- Testing
- Partial surgery preserving the prostatic apex, Conventional endoscopic prostatic surgery
- Where
- 17 sites in France
- Volunteers
- 336 people
- Sponsor
- University Hospital, Bordeaux
Benign Prostatic Hyperplasia
A Clinical Trial Comparing Laser TURP With and Without Dutasteride.
The purpose of this research study is to determine if the study drug Dutasteride taken before and after Laser TURP(Transurethral Resection of the Prostate), can provide effective and safe, long term improvement of lower urinary…
- Trial name
- NCT00431626
- Testing
- Dutasteride (Avodart)
- Volunteers
- 4 people
- Sponsor
- Northwestern University
Inflammation, Lower Urinary Tract Symptoms
Nomogram to Diagnose Prostatic Inflammation (PIN) in Men With Lower Urinary Tract Symptoms
Rationale: Histological inflammation of the prostate is a common finding in the results of the histopathological examinations after a prostate biopsy or a transurethral or open prostatectomy.
- Trial name
- PIN (NCT04856748)
- Where
- 7 sites in Cyprus, France and 4 more
- Volunteers
- 423 people
- Sponsor
- Institute for Monitoring of Urogenital Diseases