Clinical trials: Benign Hyperplasia of Prostate
Benign Prostatic Hyperplasia
Pilot Study Investigating Safety and Efficacy of Tadalafil as Treatment for Benign Prostatic Hyperplasia (BPH) in Asian Men
The primary purpose of this clinical trial is to evaluate the change in the International Prostate Symptom Score (IPSS) total score from the beginning of the study to the end of the study for subjects randomized to tadalafil 5mg…
- Trial name
- NCT00540124
- Testing
- Tadalafil, Tamsulosin
- Where
- 5 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Eli Lilly and Company
Intraoperative Floppy Iris Syndrome, Cataract
Comparing the Efficiency of Two Approaches in Patients at Risk of Developing Intraoperative Floppy Iris Syndrome
Intraoperative Floppy Iris Syndrome (IFIS) is a potentially serious cataract surgery complication. IFIS is most commonly associated with the chronic use of tamsulosin and other alpha1-adrenergic receptor antagonists prescribed in…
- Conditions
- Intraoperative Floppy Iris Syndrome, Cataract, Age-related Cataract, Adrenergic Receptor Antagonist Adverse Reaction
- Trial name
- NCT06266962
- Testing
- 1% Atropine drops, Epinephrine
- Where
- Czechia
- Volunteers
- 164 people
- Sponsor
- University Hospital Olomouc
Prostate Cancer
UroLift System With SAbR for Prostate Cancer and BPH
Confirming safety of combining UroLift System prior to SAbR for patients with newly diagnosed prostate cancer and a history of BPH, by measuring the acute complication rate of UroLift System implant in patients with BPH…
- Trial name
- NCT05311527
- Testing
- Urolift, SABR
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Texas Southwestern Medical Center
BPH (Benign Prostatic Hyperplasia)
Comparison of Holmium, Thulium:YAG, and Thulium Fiber Lasers in Prostate Enucleation
Benign prostatic hyperplasia (BPH) is a common condition in aging men and may require surgical treatment when medical therapy is ineffective.
- Trial name
- TRI-LASER (NCT07350005)
- Testing
- Holmium:YAG Laser Prostate Enucleation, Thulium:YAG Laser Prostate Enucleation, Thulium Fiber Laser Prostate Enucleation
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Ankara University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Ultrasound IPP to Predict Response to Medical Therapy in LUTS/BPH
This prospective cohort study evaluated whether transabdominal ultrasound measurement of intravesical prostatic protrusion predicts symptom severity and response to medical therapy in men aged 50 years or older with lower urinary…
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Bladder Outlet Obstruction
- Trial name
- NCT07306767
- Testing
- Transabdominal ultrasound measurement of intravesical prostatic protrusion, Alpha-adrenergic blocker, 5-alpha reductase inhibitor
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia
A Study in Men With Benign Prostatic Hyperplasia
The purpose of the study is to determine whether LY500307 helps symptoms of Benign Prostatic Hyperplasia (BPH)
- Trial name
- NCT01097707
- Testing
- LY500307
- Where
- 70 sites in United States, Australia and 6 more
- Volunteers
- 414 people
- Sponsor
- Eli Lilly and Company
Benign Prostatic Hyperplasia (BPH)
China Greenlight Registry Study (Post-market)
The duration of the study is expected to take approximately 3 years, which includes a recruitment period of approximately 12-months and 2 years (24-months) to complete procedure and follow-up visits.
- Trial name
- NCT03736512
- Testing
- GreenLight XPS™ 532 nm Laser System with MoXy™ laser fiber
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Boston Scientific Corporation
Benign Prostatic Hyperplasia
Transperineal Irreversible Electroporation for Benign Prostatic Hyperplasia
This clinical trial focuses on men with benign prostatic hyperplasia (BPH), a condition in which an enlarged prostate causes urinary problems.
- Trial name
- NCT06867315
- Testing
- Composite steep-pulse therapeutic device (CNP-III)
- Where
- 10 sites in China
- Volunteers
- 99 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Benign Prostatic Hyperplasia
Α Prospective Observational Study for the Evaluation of Disease Control and Quality of Life in Patients With Benign PROStatic hyPERplasia Under Fixed Dose combΙnaTion Treatment With Dutasteride and Tamsulosin . PROSPERITY Group of Studies (I&II)
Investigation of the efficacy and safety of the stable combination of dutasteride and tamsulosin (Dinaplex®) in the Greek population as well as the evaluation of the quality of life of patients with benign prostatic hyperplasia…
- Trial name
- PROSPERITY (NCT04831476)
- Testing
- Patients with Benign Prostate Hyperplasia
- Where
- Greece
- Volunteers
- 1,296 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Benign Prostate Hyperplasia
A Study to Evaluate the Efficacy and Safety of ASP4901 in Patients With Benign Prostate Hyperplasia
The purpose of this study is to compare the efficacy of ASP4901 with placebo in patients with benign prostatic hyperplasia. The safety and tolerability of ASP4901 will also be evaluated.
- Trial name
- NCT02038868
- Testing
- ASP4901, Tamsulosin
- Where
- 2 sites in Japan
- Volunteers
- 320 people
- Sponsor
- Astellas Pharma Inc
Benign Prostatic Hyperplasia
A Phase 3 Clinical Trial to Evaluate the Efficacy and Safety of HCP1303 Capsules
The main objective of this study is to evaluate efficacy and safety of HCP1301 capsule in patients with Benign Prostatic Hyperplasia and Erectile Dysfunction
- Trial name
- NCT02667938
- Testing
- HCP1303 capsule 5/0.2mg, HCP1303 capsule 5/0.4mg, HGP1201
- Volunteers
- 510 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
BPH (Benign Prostatic Hyperplasia)
KTP Green Light Prostatectomy Compared With TUR-P in High Risk Patients
The purpose of this study is to compare safety and efficacy of Green Light PVP (Photoselective Vaporization of the Prostate) compared to TUR-P in high risk patients
- Trial name
- NCT02075736
- Testing
- KTP laser, TUR-P
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- University of Helsinki
Lower Urinary Tract Symptoms
UK ROPE Register Study
This registry study enables us to collect data on the treatment of LUTS using prostate artery embolisation (PAE), and other surgical methods to answer the following questions posed by NICE in 2013: Is PAE a safe and effective…
- Trial name
- UK ROPE (NCT02434575)
- Where
- 17 sites in United Kingdom
- Volunteers
- 318 people
- Sponsor
- Cardiff and Vale University Health Board
Benign Prostate Hyperplasia
Plasmakinetic Enucleation of the Prostate and Open Prostatectomy to Treat Large Prostates
The investigators hypothesize that Plasmakinetic Enucleation of the Prostate (PkEP) might yield functional results comparable to OP but with lower perioperative morbidity, and have equivalent long-term efficacy with OP for large…
- Trial name
- NCT01952912
- Testing
- PkEP, OP
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Fuzhou General Hospital
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Clinical Trial to Compare the Solifenacin/Tamsulosin Combination Therapy With Tamsulosin Monotherapy for LUTS Due to BPH
Clinical Trial to Compare the Efficacy and Safety of Solifenacin/Tamsulosin Combination Therapy with Tamsulosin Monotherapy for Lower Urinary Tract Symptoms due to Benign Prostatic Hyperplasia
- Trial name
- NCT02972268
- Testing
- Tamsulosin 0.2mg + Solifenacin 5mg
- Where
- South Korea
- Volunteers
- 780 people
- Sponsor
- Jeil Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Water Vapor Thermal Therapy Versus Ejaculation-Preserving HoLEP for Benign Prostatic Hyperplasia
This prospective comparative study will evaluate Water Vapor Thermal Therapy (Rezum) versus ejaculation-preserving Holmium Laser Enucleation of the Prostate (EP-HoLEP) in sexually active men with symptomatic benign prostatic…
- Trial name
- NCT07648875
- Testing
- Water Vapor Thermal Therapy, Ejaculation-Preserving Holmium Laser Enucleation of the Prostate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Prostatic Hyperplasia
Dutasteride (GI198745) In Benign Prostatic Hyperplasia Subjects
This study will assess the efficacy and safety of GI198745 0.5mg given once daily for 52 weeks to Benign Prostatic Hyperplasia (BPH) patients.
- Trial name
- NCT00368979
- Testing
- Dutasteride
- Where
- 26 sites in Japan
- Volunteers
- 378 people
- Sponsor
- GlaxoSmithKline
Male Urogenital Diseases, Genital Diseases, Male
Office Based Transperineal Laser Ablation for Benign Prostatic Hyperplasia HYPERPLASIA
This study is set up as a phase I-II prospective, single center, interventional pilot study carried in Office setting under local anesthesia.
- Conditions
- Male Urogenital Diseases, Genital Diseases, Male, Prostatic Disease, Prostatic Hyperplasia
- Trial name
- NCT04760483
- Testing
- SoracteLite(TM) TPLA for BPH
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Benign Prostatic Hyperplasia
A Clinical Trial to Evaluate the Bioequivalence of AD-116A Compared to AD-1161 in Healthy Adult Male Volunteers
The study compare and evaluate the bioequivalence between the administration of AD-116A and the administration of AD-1161 in healthy adult male volunteers
- Trial name
- NCT07715305
- Testing
- AD-116A, AD-1161
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Addpharma Inc.
Prostatic Hyperplasia, Impotence
Effect of Vardenafil on Blood Pressure in Patients With Erectile Dysfunction Who Received Concomitant Doxazosin GITS
The purpose of this study is to investigate the interaction between doxazosin GITS and vardenafil on blood pressure (Both systolic and diastolic blood pressure) in patients with both ED and BPH.
- Trial name
- NCT00517179
- Testing
- Vardenafil 10mg
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Hospital Authority, Hong Kong