Clinical trials: Benign Hyperplasia of Prostate
Prostatic Hyperplasia
Establishing the Benefits of Adherence to Enlarged Prostate Treatment: A Validation Study Linking Adherence to Outcomes Using the Market Scan Database
Adherence and length of therapy with 5-alpha reductase inhibitor (5ARI) treatment may be associated with improved clinical outcomes of enlarged prostate (EP) as well as lower health care costs.
- Trial name
- NCT01381510
- Testing
- 5-alpha Reductase Inhibitor (5ARI)
- Volunteers
- 54,459 people
- Sponsor
- GlaxoSmithKline
Benign Prostate Hyperplasia
Safety, Efficacy, and Short-Term Outcomes of Rezūm Water Vapor Thermal Therapy for Benign Prostatic Hyperplasia Under Local Anesthesia With Intravenous Sedation: A Single-Center Retrospective Study of 129 Patients in the Kurdistan Region of Iraq
This single-center retrospective study evaluates the safety, feasibility, and short-term clinical outcomes of Rezūm water vapor thermal therapy (WVTT) for the treatment of lower urinary tract symptoms (LUTS) secondary to benign…
- Trial name
- NCT07507591
- Testing
- Rezum Water Vapor Thermal Therapy
- Where
- Iraq
- Volunteers
- 129 people
- Sponsor
- ALI KAMAL M. SAMI
Prostate Cancer, Prostate Adenocarcinoma
Customized TULSA-PRO Ablation Registry
This patient registry will capture data from patients who have been or who are undergoing the transurethral ultrasound ablation (TULSA) procedure as part of their routine clinical care.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Benign Prostatic Hyperplasia
- Trial name
- CARE (NCT05001477)
- Testing
- TULSA Procedure
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Profound Medical Inc.
Benign Prostatic Hyperplasia
Early Apical Release vs Classic Holmium Laser Enucleation of the Prostate: Randomized Controlled Trial Comparing Post-Operative Incontinence Rates and Surgical Outcomes
To determine if early apical release holmium enucleation of the prostate (EAR HoLEP), as a surgical treatment for benign prostatic hyperplasia, reduces post-operative urinary incontinence compared to classic HoLEP.
- Trial name
- HoLEP EAR (NCT04566588)
- Testing
- EAR HoLEP, Classic HoLEP
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Kansas Medical Center
BPH, BOO - Bladder Outflow Obstruction
Long Term Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients Who Completed 12 Months of Follow-Up Post Implantation (Continuation Study for Study BM-011-IL)
This study evaluates the long term safety and efficacy of use of the Butterfly Medical's prostatic retraction device in Benign Prostatic Hyperplasia (BPH) Patients.
- Conditions
- BPH, BOO - Bladder Outflow Obstruction, Enlarged Prostate (BPH)
- Trial name
- NCT05330520
- Testing
- Butterfly Medical Prostatic Retraction Device ("the Butterfly device") removal/replacement
- Where
- 2 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Butterfly Medical Ltd.
Prostatic Hyperplasia, Prostate Hyperplasia
Efficacy of α-blocker or 5-ARI Withdrawal to Continued Combination Therapy on the Maintenance of LUTS in Men With BPH
The investigators compare the efficacy of alpha-blocker and 5-ARI withdrawal to continued combination therapy on the maintenance of LUTS and improvement of quality of life outcomes in men with benign prostatic hyperplasia.
- Conditions
- Prostatic Hyperplasia, Prostate Hyperplasia, Prostatic Hypertrophy
- Trial name
- NCT05023824
- Testing
- alpha-blocker or 5-ARI withdrawal, Maintenance of alpha-blocker and 5-ARI
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Gangnam Severance Hospital
Benign Prostatic Hypertrophy Requiring Surgical Intervention
Randomized Controlled Trial Comparing Two Different Morcellators for HoLEP Procedures
To compare efficiency, in terms of tissue morcellation and removal time, of two commercially available FDA-approved morcellators: the VersaCut and the Piranha in subjects undergoing HoLEP procedure for benign prostatic…
- Trial name
- NCT02195622
- Testing
- Lumenis VersaCut Morcellator, Wolf Piranha Morcellator
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Indiana Kidney Stone Institute
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Comparison Between Water Vapor Thermal Therapy and Prostatic Artery Embolization in Treatment of Benign Prostatic Hyperplasia
The aim of this study is to compare the effectiveness of Rezum therapy versus Prostatic Artery Embolization in managing moderate-to-severe lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH), with the…
- Trial name
- NCT07416227
- Testing
- Rezum, Prostatic Artery Embolization
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Prostate Hyperplasia, Prostatic Hypertrophy
Low Energy HoLEP on IPSS
The purpose of this study is to prove that low-energy (30W) Holmium laser prostatectomy (Holeb) is not inferior to high-energy (100W) Holmium laser prostatectomy (safety and effectiveness)
- Conditions
- Prostate Hyperplasia, Prostatic Hypertrophy, Surgery, Bladder Outlet Obstruction
- Trial name
- NCT04514718
- Testing
- Holmium laser
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Prostatic Hyperplasia, Urinary Retention
Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up
The purpose of the study is to compare two alpha blockers, terazosin and doxazosin GITS, in achieving a successful TWOC after AUR due to BPH, among Chinese males in Hong Kong, and in delaying or avoiding a TURP.
- Trial name
- NCT00563485
- Testing
- Doxazosin GITS (Cardura XL), Terazosin (Hytrin)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hospital Authority, Hong Kong
BPH (Benign Prostatic Hyperplasia)
Effetivity of Dutasteride and Aloe Vera Extract Combination on Angiogenesis and Obstruction on Benign Prostatic Hyperplasia
This study is a double blinded RCT with pre-post test design on the effect of combination of dutasteride and aloe vera, compared to dutasteride only, on uroflowmetry results, prostate volume, and VEGF serum level among patients…
- Trial name
- ALOE-DUTA-BPH (NCT07065682)
- Testing
- Aloevera + dutasteride, Dutasteride (0.5mg)
- Where
- Indonesia
- Volunteers
- 84 people
- Sponsor
- Universitas Diponegoro
Benign Prostatic Hyperplasia
High Power Thulium Vaporization vs Transurethral Resection of the Prostate for Treatment of BPH
the investigators plan to test Thulium laser vaporization using high power ( 200w ) Front fire vaporization compared to standard M-TURP in reduction of LUTS secondary to BPH in a prospective randomized trial.
- Trial name
- NCT03264482
- Testing
- M-TURP, THUVAP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Benign Prostate Enlargement
Electromagnetic Field Therapy Versus Aerobic Exercise on Prostatic Function in Elderly With Benign Prostatic Hyperplasia
This study will be carried out on seventy five elderly patients with benign prostatic hyperplasia. Their age will range from 60 to 75 years old.
- Trial name
- NCT07357168
- Testing
- pulsed electromagnetic field, Treadmill machine
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Ejaculation Abnormal, BPH With Urinary Obstruction
Ejaculation Preserving Photoselective Vaporization Versus Plasma Kinetic Vaporization Versus Transurethral Resection Of The Prostate: A RCT
To Evaluate and compare the outcome and coast of ejaculation sparing management of BPH using 3 different techniques: PVP, PKVP and TURP. Ejaculation sparing TURP group is considered the standard control group.
- Conditions
- Ejaculation Abnormal, BPH With Urinary Obstruction, Prostatic Hyperplasia, Prostate Disease
- Trial name
- EPPROSTATECT (NCT03589196)
- Testing
- Ejaculation Preserving Photoselective Vaporization, Ejaculation Preserving Plasma Kinetic Vaporization, Ejaculation Preserving Transurethral Resection Of The Prostate
- Where
- Egypt
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Benign Prostate Hyperplasia
Holmium Laser Enucleation of Prostate(HOLEP) vs Greenlight(XPS) Laser Photoselective Vapo-Enucleation of Prostate(PVEP)
The investigators are now proposing to compare two laser techniques for treating Benign prostate hyperplasia (BPH); Holmium Laser Enucleation of the Prostate (HOLEP) versus (greenlight) XPS which is a recently available…
- Trial name
- NCT01494337
- Testing
- HOLEP, PVEP-XPS
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Royal Victoria Hospital, Canada
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Study of Light-Activated Talaporfin Sodium in Patients With Lower Urinary Tract Symptoms (LUTS) Due to Benign Prostatic Hyperplasia (BPH)
This is a phase 2 study to evaluate the safety and effectiveness of light-activated talaporfin sodium in patients with LUTS due to benign prostatic hyperplasia (BPH).
- Trial name
- NCT00918034
- Testing
- talaporfin sodium, Transurethral illumination with light emitting diodes, Placement
- Where
- 8 sites in Australia, New Zealand
- Volunteers
- 21 people
- Sponsor
- Light Sciences Oncology
Benign Prostatic Hyperplasia
A Smart Wearable Device for Monitoring Urination Function in Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH) is a common condition that can cause bothersome urination problems and reduce quality of life.
- Trial name
- NCT07357012
- Testing
- Electrical Impedance Tomography (EIT) Wearable Monitoring Device
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Peking University Third Hospital
Benign Prostate Hyperplasia, Healthy
Safety and Pharmacokinetic Characteristics of DKF-313
This is a randomized, open-label, single-dose, 2-treatment, 2-way, 2-period crossover study to evaluate the safety and the pharmacokinetic characteristics of DKF-313 (dutasteride and tadalafil) in healthy male volunteers.
- Trial name
- NCT02352311
- Testing
- DKF-313, AVODART, CIALIS
- Where
- South Korea
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Dongkook Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia, Prostate Cancer
Impact of Anticoagulants and Antiplatelets in Patients on Transurethral Resection of the Prostate
Benign prostatic hyperplasia(BPH) is a common disease in urology among old men. If BPH symptom cannot be controlled by drugs, then transurethral resection of the prostate (TURP), is recommended.
- Trial name
- NCT02822963
- Where
- Taiwan
- Sponsor
- National Cheng-Kung University Hospital
Prostate, Benign Prostatic Hyperplasia (BPH)
Inverted-T Incision With Early Apical Release vs. Three-Lobe in Holmium Laser Enucleation of The Prostate
Aim of the work is to compare the surgical efficacy and perioperative outcomes of the inverted-T incision with early apical release technique versus the standard three-lobe technique in patients undergoing Holmium Laser…
- Trial name
- NCT07642063
- Testing
- inverted-T with early apical release technique, standard three-lobe technique
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University