Clinical trials: Benign Prostate Obstruction
Benign Prostatic Hyperplasia
Bladder and Prostate Sonomorphology in Patients With Symptomatic Benign Prostatic Hyperplasia
Bladder and Prostate Sonomorphology in Patients With Symptomatic Benign Prostatic Hyperplasia?
- Trial name
- NCT04352257
- Testing
- pelvic Ultrasound
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kafrelsheikh University
Benign Prostatic Hyperplasia (BPH), Obstructive Lower Urinary Tract Symptoms (LUTS)
Prospective Post Market Clinical Trial for the Zenflow Spring System - A Minimally Invasive Treatment for LUTS Associated With BPH.
This is a prospective, randomized, open-label, parallel-group post-market clinical trial (PMCT). The overall objective of this PMCT is to compare the effectiveness, durability, and patient-centered outcomes of the Zenflow Spring…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Obstructive Lower Urinary Tract Symptoms (LUTS), Enlarged Prostate
- Trial name
- NCT07797348
- Testing
- Zenflow Arm: Zenflow Spring System implant procedure, Medical Therapy Tamsulosin
- Volunteers
- 110 people
- Sponsor
- Zenflow, Inc.
Lower Urinary Tract Symptoms, Prostate Obstruction
Intermittent vs Daily Tamsulosin for LUTS/BPH
Background: Lower urinary tract symptoms (LUTS) are common in aging men, most often due to benign prostatic hyperplasia (BPH), and significantly impair quality of life.
- Trial name
- ARAB (NCT07308002)
- Testing
- Daily Tamsulosin, Intermittent Tamsulosin
- Where
- Egypt
- Volunteers
- 288 people
- Sponsor
- Mansoura University
Localised Prostate Cancer, Locally Advanced Prostate Cancer
MRI Guided Transurethral HIFU for Various Prostate Diseases
This study assesses feasibility and safety, the primary outcomes, of MRI guided transurethral high intensity focused ultrasound (HIFU) ablation for prostate diseases (PD).
- Conditions
- Localised Prostate Cancer, Locally Advanced Prostate Cancer, Locally Recurrent Prostate Cancer, Benign Prostatic Hyperplasia
- Trial name
- HIFU-PRO (NCT03350529)
- Testing
- MRI guided transurethral HIFU ablation of prostatic tissue
- Where
- Finland
- Volunteers
- 87 people
- Sponsor
- Turku University Hospital
Prostatic Hyperplasia
Benign Prostatic Hyperplasia (BPH) Screening Tool Case Finding Study in Subjects >=50 Years
This non-randomized, interventional study will be conducted in a general practice setting to assess the utility of a benign prostatic enlargement (BPE)/benign prostatic obstruction (BPO) screening tool in conjunction with…
- Trial name
- NCT02757963
- Testing
- Benign prostatic enlargement (BPE)/Benign prostatic obstruction (BPO) screening tool, International Prostate Symptom Score (IPSS) screening tool
- Where
- 45 sites in France, Germany and 3 more
- Volunteers
- 1,679 people
- Sponsor
- GlaxoSmithKline
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Impact of 80 W KTP Laser Vaporization Prostatectomy on Severity of Obstruction in Benign Prostatic Hyperplasia
The purpose of this study is to compared the efficacy of 80W KTP photoselective laser vaporization prostatectomy (PVP) and transurethral resection of the prostate (TURP) in reducing the volume of prostate and relieving the…
- Trial name
- NCT00908427
- Testing
- photoselective vaporization prostatectomy (PVP), Transurethral resection of the prostate
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center
Benign Prostatic Hyperplasia
Comparison of Functional Outcomes of Ejaculation-preserving Partial Trans Urethral Resection of the Prostate With Complete Trans Urethral Resection of the Prostate for Benign Prostatic Obstruction
It has been demonstrated that sexual activity was common in the majority of men over 50 years old and was an important component of overall quality of life (QoL).
- Trial name
- PARTURP (NCT05574244)
- Testing
- Partial surgery preserving the prostatic apex, Conventional endoscopic prostatic surgery
- Where
- 17 sites in France
- Volunteers
- 336 people
- Sponsor
- University Hospital, Bordeaux
Disorder of the Lower Urinary Tract
Changes of microRNA Expression in Obstructive and Neurogenic Bladder Dysfunction
Patients with obstructive or neurogenic lower urinary tract disease will be invited to participate. Upon agreement they will undergo an assessment of bladder function (questionnaires) and bladder biopsies at 2 time-points.
- Trial name
- MoVe (NCT02410876)
- Testing
- Bladder biopsy, Urodynamic study
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Prostatic Hyperplasia, Benign, Prostatic Obstruction
HoLEP: Learning Curve Analysis and Comparison With TURP
This study evaluates the outcomes of Holmium laser enucleation of the prostate (HoLEP) during both the learning and expert phases compared to transurethral resection of the prostate (TURP) in managing benign prostatic obstruction…
- Trial name
- NCT06849089
- Testing
- Transurethral resection of prostate (TURP), Holmium laser enucleation of prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Marmara University
BPH, Nocturia
Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy
Benign prostate hypertrophy (BPH) and inflammation are common non-cancerous enlargement of the prostate, which result in urinary interference and incomplete drainage of the bladder.
- Conditions
- BPH, Nocturia, BPH With Urinary Obstruction, Prostatism
- Trial name
- SVF-BPN (NCT02961114)
- Testing
- Microcannula Harvest Adipose, Centricyte 1000, IV Sterile Normal Saline
- Where
- 2 sites in United States
- Sponsor
- Robert W. Alexander, MD, FICS
BPH Without Urinary Obstruction and Other Lower Urinary Tract Symptoms (LUTS)
The Effect of BRIZO on Lower Urinary Tract Symptoms (LUTS) Related to Benign Prostatic Hypertrophy (BPH)
A randomized, placebo controlled double-blind, 12-week treatment trial in men with moderate to severe symptoms of benign prostatic hyperplasia.
- Trial name
- NCT05227508
- Testing
- BRIZO
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Se-cure Pharmaceuticals Ltd.
Lower Urinary Tract Symptoms
Irreversible Electroporation Versus Standard Medication for Benign Prostatic Obstruction
Irreversible electroporation (IRE) is a novel ablation modality using electric pulses to create nanoscale defects in the cell membrane. It has been verified to be safe on the treatment of prostate, lung, liver and kidney masses.
- Trial name
- NCT03448510
- Testing
- Irreversible electroporation, Standard Medication
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Changhai Hospital
Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom
Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin
This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO).
- Conditions
- Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom, Ejaculatory Dysfunction, Anejaculation
- Trial name
- NCT06989515
- Volunteers
- 100 people
- Sponsor
- Marmara University
BPH With Urinary Obstruction
Readmission Following Prostatic Surgery
This study will be conducted to estimate readmission rate and reasons for readmission after all modalities of endoscopic transurethral surgeries for treatment of BOO secondary to BPH in the last 20 years.
- Trial name
- NCT06101576
- Testing
- TUIP, TURP, Prostate Vaporization
- Where
- Egypt
- Volunteers
- 4,000 people
- Sponsor
- Mansoura University
Bladder Neck Obstruction, Bladder Outlet Obstruction
Effectiveness and Safety of Adipose-derived Regenerative Cells for Reduction of Risk of Bladder Neck Contracture
Autologous adipose-derived regenerative cells (ADRC) will be extracted from lipoaspirate by enzymatic digestion from a portion of the fat harvested from the patient's front abdominal wall.
- Conditions
- Bladder Neck Obstruction, Bladder Outlet Obstruction, Benign Prostatic Hyperplasia, Urinary Bladder Neck Obstruction
- Trial name
- NCT02869061
- Testing
- Liposuction, Transurethral bladder neck resection., ADRC
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation
Bladder Outlet Obstruction
An Open Label Study to Measure Efficacy of Fesoterodine (Toviaz) Post Surgery for Benign Prostatic Hyperplasia
The subjects who have symptoms of overactive bladder (many trips to the bathroom, and urgency with or without the inability to hold your urine until you get to the toilet) are invited to participate in this research study.
- Trial name
- Toviaz (NCT00605319)
- Testing
- Toviaz (Fesoterodine)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Benign Prostate Enlargement, Benign Prostate Hypertrophy(BPH)
Oxiblume:CoQ10 (Ralivia) Therapy for Benign Prostatic Hyperplasia:
Objectives of the study The aim of the study is to investigate and compare the treatment efficacy and safety of Oxiblume:CoQ10 (Ralivia) therapy vs placebo for BPH patients Study center The study will be coordinated by the…
- Conditions
- Benign Prostate Enlargement, Benign Prostate Hypertrophy(BPH), Benign Prostate Obstruction (BPO)
- Trial name
- NCT07638865
- Testing
- Oxiblume:CoQ10 (Ralivia) therapy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- G.Gennimatas General Hospital
Benign Prostate Hypertrophy(BPH)
Transurethral Focal Laser Ablation Versus Transurethral Prostatectomy For Management Of Benign Prostatic Obstruction
Introduction and objectives: Laser prostatectomy has become an increasingly popular and effective alternative to transurethral resection of the prostate (TURP) for the treatment of benign prostatic hyperplasia (BPH).-.
- Trial name
- NCT07196475
- Testing
- FOCAL LASER ABLATION OF PROSTATE
- Where
- Egypt
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Prostate Hyperplasia, Benign Prostatic Hyperplasia
Transperineal Laser Ablation vs Transurethral Resection for Benign Prostatic Obstruction: A Randomized Clinical Trial
The primary objective of the study is to compare Trans-Perineal Laser Ablation of Prostate versus Trans-Urethral Resection of Prostate in the immediate impact on post-operative pain; in terms of relief in benign prostatic…
- Conditions
- Prostate Hyperplasia, Benign Prostatic Hyperplasia, Benign Prostatic Hypertrophy, Benign Prostatic Hypertrophy With Outflow Obstruction
- Trial name
- NCT04781049
- Testing
- Trans-Perineal Laser Ablation of Prostate, Trans-Urethral Resection of Prostate
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- San Carlo di Nancy Hospital
RANDOMIZED
Treatment for Benign Prostatic Obstruction: Transperineal Laser Ablation
THIS STUDY IS A RANDOMIZED CLINICAL TRIAL COMPARING TRANSURETHRAL PROSTATE RESECTION (TURP) AND ECHOLASER SORACTELITE-TRANSPERINEAL LASER ABLATION (TPLA) IN PATIENTS WITH LOWER URINARY TRACT SYMPTOMS DUE TO BENIGN PROSTATIC…
- Trial name
- NCT07289243
- Testing
- ECHOLASER-TPLA, TURP
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari