Clinical trials: Benign Prostatic Hyperplasia
Benign Prostatic Hyperplasia
Thulium Laser Versus Bipolar Enucleation of the Prostate
Comparing the peri-operative outcomes in patients with benign prostatic hyperplasia (BPH) who will undergo bipolar enucleation of the prostate versus thulium laser enucleation.
- Trial name
- NCT05200065
- Testing
- Thulium laser enucleation of the prostate, Bipolar enucleation of the prostate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Benign Prostate Hypertrophy(BPH)
Efficacy and Tolerability of Treatment With Alfalitic Plus Serenoa Repens Compared to Alfalitic Plus Antimuscarinic for Moderate-severe Lower Urinary Tract Symptoms
The study aims to investigate, through the International Prostatic Symptoms Score (IPSS) questionnaire, the non-inferiority of the therapy with the alpha-blockers+Serenoa repens combination compared to the…
- Trial name
- FINAL (NCT07665749)
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Silodosin vs Tamsulosin for LUTS Due to BPH: A Randomized Crossover Trial
The goal of this randomized crossover clinical trial is to compare the efficacy and safety of Silodosin versus Tamsulosin in patients with moderate to severe lower urinary tract symptoms due to Benign Prostatic Hyperplasia.
- Trial name
- NCT07467343
- Testing
- Silodosin, Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Prostatic Hypertrophy, Benign
Assessing the Impact of the PVP With Greenlight Laser Using Prostatic MRI and Contrast-enhanced Ultrasound
The PVP by Greenlight laser 180W is becoming a potential therapeutic alternative in the treatment of benign prostatic hypertrophy (BPH) as recommended.
- Trial name
- PROPIL (NCT01732991)
- Testing
- prostatic photo-vaporization (PVP)
- Where
- France
- Volunteers
- 12 people
- Sponsor
- University Hospital, Tours
Benign Prostate Hypertrophy(BPH)
A Clinical Trial to Compare and Evaluate Evaluate the Pharmacokinetics and Safety of CKD-846
A Clinical trial to compare and evaluate evaluate the pharmacokinetics and safety of CKD-846
- Trial name
- NCT07404735
- Testing
- CKD-846, D091
- Where
- South Korea
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Benign Prostate Hyperplasia, Lower Urinary Tract Symptoms
HoLEP vs. Greenlight 532nm-laser PVEP vs. Bipolar TURP in Management of Moderate/ Large BPH
Most guidelines are not strict for recommending single treatment approach for Moderate to large prostate. In this study the investigators planned to test the Greenlight (532-nm) laser Photoselective Vapo-Enucleation of the…
- Trial name
- NCT02332538
- Testing
- 532nm-laser photoselective vapo-enucleation of the prostate), Holmium laser enucleation of prostate, Bipolar TURP
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- Mansoura University
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Effect of Different Dosing Regimens of Tadalafil or Tamsulosin Combined With 5α-Reductase Inhibitors on Urinary and Sexual Outcomes in Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition among aging men that causes lower urinary tract symptoms (LUTS) and may negatively affect sexual function.
- Conditions
- Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms, Erectile Dysfunction
- Trial name
- DTT-BPH (NCT07715448)
- Testing
- Tamsulosin, Tadalafil, 5-Alpha Reductase Inhibitor
- Where
- Egypt
- Volunteers
- 240 people
- Sponsor
- Beni-Suef University
Prostatic Hyperplasia, Urinary Retention
Randomized Trial Comparing Terazosin 5 mg Daily and Doxazosin GITS 4 mg Daily for Trial Without Catheter in Acute Urinary Retention With Long Term Follow up
The purpose of the study is to compare two alpha blockers, terazosin and doxazosin GITS, in achieving a successful TWOC after AUR due to BPH, among Chinese males in Hong Kong, and in delaying or avoiding a TURP.
- Trial name
- NCT00563485
- Testing
- Doxazosin GITS (Cardura XL), Terazosin (Hytrin)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Hospital Authority, Hong Kong
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Top-Down Holmium Laser Enucleation of the Prostate (HoLEP) vs the Traditional HoLEP for Treatment of Benign Prostatic Hyperplasia (BPH)
Benign prostatic hyperplasia (BPH), the non-malignant enlargement of the prostate gland, places pressure on the urethra and causes urination difficulties and bladder problems.
- Trial name
- NCT04391114
- Testing
- Traditional HoLEP, Top-Down HoLEP
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Benign Prostatic Hyperplasia
Transurethral Ventral Wall of Urethra-preserving Enucleation of Prostate
In this study, the investigators designed a randomized and double-blind prospective trial to evaluate the efficiency and safety of the investigators new approach-transurethral ventral wall of urethra-preserving enucleation of…
- Trial name
- NCT01073241
- Testing
- transurethral ventral wall of urethra-preserving enucleation of prostate, transurethral prostatic resection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Southwest Hospital, China
Benign Prostatic Hyperplasia
Pharmacokinetics and Safety/Tolerability of YY-201 in Comparison to Dutasteride and Tadalafil
A randomized, open label, single dose, two-way crossover clinical trial to investigate the pharmacokinetics and safety/tolerability of YY-201 in comparison to Dutasteride and Tadalafil administered in healthy male volunteers
- Trial name
- NCT03240939
- Testing
- Dutasteride 0.5 mg, Tadalafil 5 mg, YY-201
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yuyu Pharma, Inc.
Moderate-to-severe Benign Prostatic Hyperplasia (BPH)
Bioequivalence Study of AJU-G721 and G721R in Healthy Adult Volunteers Under Fasting Conditions
To evaluate and compare the safety and pharmacokinetic profiles of "AJU-G721" (test drug) and "G721R" (reference drug) in healthy adult male subjects.
- Trial name
- NCT07643220
- Testing
- Test Drug, Reference Drug
- Where
- South Korea
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AJU Pharm Co., Ltd.
Kidney Calculi, Urologic Diseases
Tranexamic Acid to Improve Same-day Discharge Rates After Holmium Laser Enucleation of the Prostate (HoLEP)
This study is designed to assess if there is a significant difference in same day discharge rates after Holmium Laser Enucleation of the Prostate (HoLEP).
- Conditions
- Kidney Calculi, Urologic Diseases, Benign Prostatic Hypertrophy
- Trial name
- NCT05082142
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Northwestern University
Prostatic Neoplasms, Prostate Disease
Single Dose Versus Double Dose Tamsulosin in Management of Moderate and Severe LUTS Due to BPH
Single dose versus double dose tamsulosin in Management of Moderate and severe lower urinary tract symptoms due to benign prostatic hyperplasia
- Conditions
- Prostatic Neoplasms, Prostate Disease, Prostate Obstruction, Prostate Hypertrophy
- Trial name
- NCT05834270
- Testing
- Single dose tamsulosin 0.4mg, Double dose tamsulosin 0.4mg
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Benign Prostatic Hyperplasia
B-TURP vs BipolEP in Management of BPH Patients With Medium-sized Prostates
This is a comparative study of the efficacy and safety of endoscopic bipolar transurethral resection and enucleation of the prostate in management of benign prostatic hyperplasia patients with medium-sized prostates
- Trial name
- NCT06939062
- Testing
- Bipolar enucleation of the prostate (BipolEP), Bipolar transurethral resection of the prostate (B-TURP)
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Assiut University
Prostatic Hyperplasia
Laser Vaporization of the Prostate: Comparing Between Ejaculatory Preserving and Non-ejaculatory Preserving Technique
The present work aimed to compare between The Outcomes of conventional technique of laser prostatectomy versus the new ejaculatory sparing technique .
- Trial name
- NCT06091618
- Testing
- new technique of ejaculatory preserving laser prostatectomy, conventional technique of laser vaporization of the prostate
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Benign Prostatic Hyperplasia (BPH), Lower Urinary Tract Symptoms
Prostate Artery Embolization: Single Center Experience
Benign prostatic hyperplasia (BPH) is an enlarged prostate gland from smooth muscle and glandular hyperplasia seen in the aging population with a prevalence of upto 90% in patients in the ninth decade.
- Trial name
- NCT04766268
- Testing
- Prostate artery embolization
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Benign Prostatic Hyperplasia
Thulium Fiber Laser Enucleation of the Prostate (TFLEP) vs HoLEP With Moses Technology (m-HoLEP)
Enucleation of the prostate equips technology (usually laser) to effectively treat lower urinary tract symptoms associated with benign prostate hyperplasia (BPH).
- Trial name
- NCT04807296
- Testing
- TFLEP, m-HoLEP
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lower Urinary Tract Symptoms (LUTS)
A Trial of Degarelix in Men With Lower Urinary Tract Symptoms (LUTS) Associated With Benign Prostatic Hyperplasia (BPH)
A dose-finding, multi-centre, double-blind, randomised, parallel, placebo-controlled trial to investigate efficacy and safety of degarelix in men with lower urinary tract symptoms (LUTS) associated with benign prostatic…
- Trial name
- DELUTS (NCT00947882)
- Testing
- Degarelix 10 mg, Degarelix 20 mg, Degarelix 30 mg
- Where
- 47 sites in United States, Belgium and 4 more
- Volunteers
- 404 people
- Sponsor
- Ferring Pharmaceuticals
Prostatic Hypertrophy, Benign
Vardenafil in Greenlight(TM) Laser Surgery of Benign Prostate Hypertrophy
The greenlight laser has an absorption maximum which is exactly the same as for hemoglobin. In the presence of hemoglobin, its application causes vaporization of the tissue and this effect depends on the concentration of…
- Trial name
- NCT00461123
- Testing
- Vardenafil (Levitra, BAY38-9456)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Bayer