Clinical trials: Bicuspid
Symptomatic Irreversible Pulpitis
Effect of Ultrasonic Activation of Bioceramic Sealer on Postoperative Pain in Lower Premolars
The aim of this study is to clinically compare post-operative pain levels after ultrasonic activation of Ceraseal bioceramic sealer versus non-activated bioceramic sealer for patients with symptomatic irreversible pulpitis…
- Trial name
- NCT05289791
- Testing
- ultrasonic activation of bioceramic sealer
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Appliance
Speed of Premolar Extraction Space Closure: Healed vs Recent Extraction Site
The aim was to compare the rate of teeth movement into fresh and old extraction sites.
- Trial name
- NCT04598490
- Testing
- Space closure into old extraction space, Space closure into recent extraction space
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Bicuspid Aortic Valve (BAV)
A Study of Chinese Congenital Bicuspid Aortic Valve
Pervious studies indicated that the prevalence of bicuspid aortic valve（BAV） might be higher in China. There is a familial predisposition to the development of BAV.
- Trial name
- NCT06802016
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Ruijin Hospital
Dental Implants, Osteoprotegerin
The Effect of Local Melatonin Application Around Immediately Placed Implants in the Maxillary Premolar
Background: Immediate implants provide ideal three-dimensional positioning compared to conventional implants. There may be a gap between the surface of the implant and the bone walls of the socket when it is inserted into a…
- Conditions
- Dental Implants, Osteoprotegerin, Melatonin
- Trial name
- NCT07103564
- Testing
- Immediately placed implant in maxillary premolars with local melatonin application, Immediately placed implant in maxillary premolars without local melatonin application
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Hams Hamed Abdelrahman
Apical Periodontitis, Dental Pulp Necrosis
Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial)
The goal of this clinical trial is to learn which of three common root-canal rinsing (irrigation) methods removes bacteria most effectively in adult patients who need root-canal treatment.
- Conditions
- Apical Periodontitis, Dental Pulp Necrosis, Root Canal Infection
- Trial name
- CHITO-PRE RCT (NCT07048028)
- Testing
- Chitosan Low Molecular Weight (20-200 Mpa.S), Sodium Hypochlorite, EDTA chelating agents
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ESRA DAĞCI
Anesthesia, Local
The Anesthetic Efficacy of Lidocaine and Articaine as Buccal Injection for Maxillary Premolar Teeth Extraction.
This study Is designed as a prospective randomized, single-blinded clinical trial. To evaluate The anesthetic efficacy of articaine as a buccal Injection for maxillary premolar teeth extraction, compared to lidocaine as a buccal…
- Trial name
- NCT05951907
- Testing
- Maxillary extraction without palatal injection, Maxillary extraction with buccal and palatal injection
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Bicuspid Aortic Valve (BAV), Aortic Aneurysm
Research on Aneurysm Growth Prediction in Vascular Dilation Caused by Bicuspid Aortic Valve Based on VDM and CFD
Bicuspid aortic valve (BAV) is the most common congenital valvular malformation, characterized by heterogeneous phenotypic subtypes that predispose patients to secondary aortic pathologies, including valvular dysfunction and…
- Conditions
- Bicuspid Aortic Valve (BAV), Aortic Aneurysm, TAVR
- Trial name
- NCT07782918
- Testing
- Transcatheter Aortic Valve Replacement
- Where
- 2 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Aortic Stenosis, Bicuspid Aortic Valve (BAV)
TAVR vs. SAVR Study of VitaFlow Liberty® for Severe BAV Stenosis
To evaluate the safety and effectiveness of the Transcatheter aortic valve and retrievable delivery system (VitaFlow Liberty®) for the treatment of severe bicuspid aortic valve (BAV) stenosis.
- Trial name
- PROMIS-BAV (NCT06597188)
- Testing
- VitaFlow Liberty, Commercially available surgical bioprosthetic valve
- Where
- China
- Volunteers
- 452 people
- Sponsor
- Shanghai MicroPort CardioFlow Medtech Co., Ltd.
Edentulous Alveolar Ridge
Zero Echo Time MR for the Assessment of Maxillary Sinus and Dental Regions
The aim of this study is to evaluate the efficacy of zero echo time magnetic resonance imaging (ZTE MRI) as an ionizing radiation-free diagnostic method to evaluate both hard and soft tissues and maxillary sinus region before…
- Trial name
- ZTE-DENTAL (NCT06449443)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Third Molar Impaction
The Effect of Different Treatment Modalities of Class II Malocclusion on Upper Third Molars.
What is the effect of the different treatment modalities (distalization versus upper premolar extraction) of class II malocclusion on the position, inclination and incidence of impaction of the upper third molars?
- Trial name
- NCT06098885
- Testing
- extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Clinical Performance
Clinical Performance of Nano Fiber Reinforced Versus Conventional Nano Hybrid Composite in Restoring Premolars
In patients that need composite restorations in a compound proximal carious lesions in premolars, will the clinical performance of nano fiber reinforced resin composite restorations have similar results compared to those restored…
- Trial name
- NCT05808075
- Testing
- NovaProTM Fill Universal Dental Composite
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Treatment Via Premolar Extraction
Effect of Extraction Versus Non-extraction Orthodontic Treatment on the Third Molars
What is the effect of extraction orthodontic treatment in comparison to non- extraction treatment on the position, inclination and incidence of impaction of the third molars?
- Trial name
- NCT04857658
- Testing
- extraction orthodontic treatment plan
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative, Endodontically Treated Teeth
Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation
The objective of this double-blind, randomized controlled clinical study will be to evaluate the effect f PBM on pain after endodontic instrumentation in the single-session treatment of upper molars and premolars.
- Trial name
- NCT06253767
- Testing
- Endodontic Treatment, Low Level Laser Therapy, Simulation Low Level Laser therapy
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Gingival Health, Crowding of Anterior Mandibular Teeth
To Compare the Effects of Lip Bumper Appliance in Rate of Lower Incisor Alignment After First Premolar Extractions
The goal of this clinical trial is to check the effects of lip bumper appliance contribution to driftodontics after designated tooth extractions that are already part of orthodontic treatment plan.
- Trial name
- NCT06929754
- Testing
- Lip bumper
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahria University
Orthodontic Appliance
Speed of Premolar Extraction Space Closure: Every Visit Replacement of Working Archwire
The aims of this trial were to assess the effect of changing 0.019X0.025-inch SS working archwire monthly on the rate of space closure, to compare the frictional resistance of unchanged and new working archwires in-vitro, and to…
- Trial name
- NCT04549987
- Testing
- Space closure without changing working archwire monthly, Space closure withchanging working archwire monthly
- Where
- Jordan
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Bicuspid Aortic Valve
Bicuspid Aortic Valve (BAV) Registry
The purpose of this registry is to gather information on patients with bicuspid aortic valve disease.
- Trial name
- BAV (NCT01756222)
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Graft; Complications
Socket Preservation Using Autogenous Bone Graft Versus MPM
Studying the comparative effectiveness of socket preservation using autogenous bone graft versus MPM for implant insertion.
- Trial name
- NCT03008538
- Testing
- MPM(Mineralized plasmatic matrix)., Autogenous Bone Graft
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aortic Stenosis
A Study of Transcatheter Aortic Valve Replacement Case Selection and Valve Sizing Using the ABC Bicuspid Sizing Algorithm
The goal of this study is to learn what effects the ABC Bicuspid Sizing Algorithm has on the clinical outcomes of patients with bicuspid aortic stenosis after having a transcatheter aortic valve replacement (TAVR) using the…
- Trial name
- NCT06991517
- Testing
- The ABC Bicuspid Sizing Algorithm
- Where
- 20 sites in Australia, Canada and 6 more
- Volunteers
- 290 people
- Sponsor
- World Health Research Inc.
Necrotic Pulp
Effect of Propolis Nanoparticles on Postoperative Pain and Bacterial Reduction in Mandibular Premolars
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using 20mg/ml propolis nanoparticles extract solution during chemo-mechanical preparation, versus…
- Trial name
- NCT05146713
- Testing
- Propolis nanoparticles extract solution, sodium hypochlorite
- Volunteers
- 44 people
- Sponsor
- Cairo University
Malocclusion, Long Face Syndrome
Effect of Extraction Vs Non-extraction Orthodontic Treatment on Vertical Facial Dimension
The aim of the current clinical trial was to evaluate the effects of premolar extractions compared with non-extraction orthodontic treatment on the skeletal vertical dimension of the face.
- Conditions
- Malocclusion, Long Face Syndrome, Crowding, Tooth
- Trial name
- NCT04151875
- Testing
- Extraction orthodontic treatment, Non-extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University