Clinical trials: Bicycling
Respiratory Failure
Inspiratory Effort at Different Expiratory Cycling and Airway Resistance During Pressure Support Ventilation (CYCLOPES)
The goal of this prospective interventional crossover randomized physiological study is to investigate the reliability of Pressure Muscle Index (PMI) - as an estimation of inspiratory effort - at different levels of expiratory…
- Trial name
- CYCLOPES (NCT05952726)
- Testing
- Expiratory cycling change at different levels of pressure support ventilation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
Exercise Physiology, Cardiorespiratory Fitness
IL-6 and Cortisol Responses to Cycling Exercise
This study aimed to investigate salivary interleukin-6 (IL-6) and cortisol responses following short-term and long-term cycling exercise in team athletes with different cardiorespiratory fitness levels.
- Conditions
- Exercise Physiology, Cardiorespiratory Fitness, Interleukin-6, Cortisol
- Trial name
- NCT07681362
- Testing
- Wingate Anaerobic Cycling Test, YMCA Submaximal Cycling Test
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Bipolar II Disorder, Major Depressive Episode
Open-Label Study of Geodon in Non-Rapid Cycling Bipolar II Patients With Major Depression
The purpose of this study is to evaluate the antidepressant effectiveness of Geodon for the treatment of patients diagnosed with Bipolar II disorder who are currently experiencing a major depressive episode.
- Trial name
- NCT00237666
- Testing
- Ziprasidone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- The Medical Research Network
Parkinson Disease
In-home Cycling for Individuals With PD: Feasibility
This study will examine the influence of social support on exercise frequency, duration, quality of life, and overall activity level.
- Trial name
- NCT04300023
- Testing
- Social Cycling Group
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Wisconsin, Madison
Cerebrovascular Accident
Can Arm and Leg Cycling Exercise Improve Walking After Stroke
It has been found that arm and leg cycling is similar to walking. Thus, the objective of this research is to determine if arm and leg cycling can be used to improve walking ability in a post-stroke population.
- Trial name
- NCT02316405
- Testing
- Arm and Leg Cycling Exercise for Walking after Stroke
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Victoria
Decompression Sickness, SCUBA Diving
High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation
The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving.
- Trial name
- NCT02064361
- Testing
- High intensity exercise
- Where
- 2 sites in United States, Croatia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Split
Physical Activity
Development and Feasibility of an Incentive Scheme to Promote Walking/Cycling to School
The aim of this study is to investigate whether an incentive scheme is a feasible approach to increase walking/cycling to school.
- Trial name
- RIGHT_TRACKS (NCT02282631)
- Testing
- Incentive scheme
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Prostate Cancer
Docetaxel With Rapid Hormonal Cycling as a Treatment for Patients With Prostate Cancer
We postulate that multiple apoptototic events are indusce through testosterone depletion and repletion with taxotere given in conjunction with androgen withdrawal.
- Trial name
- NCT00587431
- Testing
- GnRh (Leuprolide), Testosterone Gel, Docetaxel
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Cardiovascular Disease
Exercise Test and Cardiac Injury
Strenuous exercise in apparent healthy individuals increases plasma (high sensitive) troponin levels. The underlying mechanism is not yet elucidated, but could be explained by changes due to a mismatch in oxygen demand and supply…
- Trial name
- NCT01660828
- Testing
- remote ischemic preconditioning (RIPC)
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy
Load and Hold: Impact of 7-Day Creatine Monohydrate Loading on Breath-Hold Cycling Performance
The present study aims to investigate the effects of creatine monohydrate supplementation on maximal breath-hold exercise performance on a bicycle ergometer in trained breath-hold divers.
- Trial name
- BREATHE-C (NCT07233707)
- Testing
- Creatine Monohydrate
- Where
- Greece
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Acute Respiratory Failure
SmartCare Driven Pressure Support-Non Invasive Ventilation Feasibility Study
Knowledge-based systems were initially developped to automatically adapt pressure support settings during invasive ventilation, and proved to be at least as efficient as experienced clinicians.
- Trial name
- NCT01870089
- Testing
- SmartCare/PS-NIV Drägerwerk Lübeck Germany
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University of Lausanne Hospitals
High-Frequency Microsatellite Instability, Mismatch Repair Gene Mutation
Cycling in Preventing Colorectal Cancer in Participants With Lynch Syndrome
This trial studies how well cycling works in preventing colorectal cancer in participants with Lynch syndrome. Exercise such as cycling may reduce colorectal cancer risk in participants with Lynch syndrome.
- Conditions
- High-Frequency Microsatellite Instability, Mismatch Repair Gene Mutation, Mutation-Negative Lynch Syndrome, Mutation-Positive Lynch Syndrome
- Trial name
- NCT03495674
- Testing
- Exercise Intervention, Informational Intervention, Monitoring Device
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- M.D. Anderson Cancer Center
Ultra-marathon Runners
Difference in Central Fatigue During Two Ultra-endurance Practices: Running vs. Cycling
The mechanisms contributing to muscle fatigue in extreme long-duration exercise bouts are poorly understood. Ultra-endurance exercise is an excellent model for the study of adaptive responses to extreme loads and stress and it is…
- Trial name
- FAT-CENTR (NCT04511858)
- Testing
- maximum effort test on a cycloergometer, maximum effort test on a treadmill
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Colorectal Cancer
The Microbrect-FFC Study
This study will focus on two points: 1. To determine if response to neoadjuvant chemoradiotherapy treatment in rectal cancer can be predicted by analysing data from Fast Field Cycling imaging (FFC), a novel type of MRI technique.
- Trial name
- NCT06236321
- Testing
- Fast Field Cycling MRI scan, Provision of saliva and faecal samples
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Aberdeen
Incomplete Spinal Cord Injury
Non-invasive Brain Stimulation Paired With FES Cycling Post SCI
This project is randomized controlled trial which will explore the effect of pairing repetitive Transcranial Magnetic Stimulation (rTMS) with Functional Electrical Stimulation (FES) Cycling on lower extremity function in people…
- Trial name
- NCT05975606
- Testing
- repetitive transcranial magnetic stimulation (rTMS), functional electrical stimulation (FES) cycling
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Western University, Canada
Cardiac Disease, Critical Illness
In-Bed Cycling in ICU Patients Post Cardiac Surgery
The purpose of this study is to determine if in-bed cycling is safe and feasible in critically-ill patients after open heart surgery.
- Conditions
- Cardiac Disease, Critical Illness, Critical Illness Polyneuropathy, Critical Illness Myopathy
- Trial name
- CardiO Cycle (NCT02976415)
- Testing
- In-Bed Cycling
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Hamilton Health Sciences Corporation
Exercise Training, Exercise Behavior
Adaptive Self-Efficacy-Based AI Coaching for Cycling
The primary objective of this study is to evaluate whether adaptive, AI-delivered personalized self-efficacy-based AI coaching based on real-time physiological and performance feedback enhance indoor cycling power output during a…
- Conditions
- Exercise Training, Exercise Behavior, Exercise Adherence Challenges, Motivation for Physical Activity
- Trial name
- AI (NCT07318233)
- Testing
- Group 1: Self-efficacy-based AI coaching, Group 2: Static AI Affirmations
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Chronic Pulmonary Disease
Comparison of Multiple Exercise Trainings in Chronic Respiratory Disease
The present study aims to investigate the effect of different exercise training in patients with chronic respiratory disease.
- Trial name
- NCT05760352
- Testing
- Eccentric bike, Helmet ventilation
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Fu Jen Catholic University
Spinal Cord Injuries
The Effect of Functional Electrical Stimulation Cycling Ergometry in Addition to Robotic Rehabilitation
Spinal cord injury (SCI) is a devastating neurological condition resulting from either traumatic or non-traumatic causes, leading to loss of motor, sensory, and autonomic functions in individuals.
- Trial name
- NCT06541197
- Testing
- Robotic rehabilitation combined with Functional Electrical Stimulation (FES) bicycle ergometry group, Robotic rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Multiple Sclerosis
Effects of Cycling and Virtual Reality on Thinking Speed in Persons With MS (PACE-MS)
To compare the effects of cycling exercise with different types of virtual reality on processing/thinking speed in persons with multiple sclerosis (MS).
- Trial name
- PACE-MS (NCT06191380)
- Testing
- PACE-MS
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Kessler Foundation