Clinical trials: Bifidobacterium
- Condition Bifidobacterium
- Funder type Industry (pharma, biotech, devices)
- Accepts healthy volunteers yes
Signs and Symptoms, Digestive, Dyspepsia
Evaluation of the Effect of a Probiotic Supplement Upon Gastrointestinal Function
The purpose of this pilot study is to evaluate whether a probiotic supplement improves gastrointestinal (GI) function.
- Trial name
- NCT02928484
- Testing
- Probiotic mix CBP-004019/C
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Healthy
Influence of Food Matrix on Prebiotic Efficacy in Inulin Type Fructans
The aim of the study is to investigate whether the food matrix has an influence on the prebiotic efficacy (bifidobacteria growth) of chicory-derived Orafti® inulin in healthy adult volunteers.
- Trial name
- NCT05581615
- Testing
- Inulin
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
A03 - Digestive System, B03 - Bacteria
Fermented Dairy Product and Bifidobacterium Diversity (ThreeBees)
Bifidobacterium strains with potential health benefits can contribute to the gastrointestinal wellbeing. However, the ability of these strains to survive gastro-intestinal tract stress and their impact on gut microbiome remains…
- Trial name
- ThreeB (TB) (NCT06799364)
- Testing
- 28-days consumption of Product A in 45 to 60-year-old healthy subjects., 28-days consumption of Product B in 45 to 60-year-old healthy subjects., 28-days consumption of Control product in 45 to 60-year-old healthy subjects.
- Where
- 3 sites in France
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Reduction of Small Intestinal Ulceration Risk
The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage
To investigate if a daily dose of minimum 15 billion CFU of Bif195 reduces the risk of small-intestinal tissue damage in an Ibuprofen challenge model as assessed by video capsule endoscopy in a healthy US population.
- Trial name
- PIP-I (NCT04447924)
- Testing
- Bif195
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Gastrointestinal Symptoms
Effect of Bifidobacterium Lactis HN019 on Colonic Transit Time and Digestive Symptoms
The purpose of this study was to investigate the dose response effect of Bifidobacterium lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms.
- Trial name
- NCT01171014
- Testing
- Bifidobacterium lactis HN019
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Subjective Sleep Quality, Objective Sleep Quality
Effect of B. Longum 1714™ on Sleep Quality
The aim of this study is to evaluate the effect of supplementation with the B. longum 1714™ strain on subjective and objective sleep quality in healthy participants.
- Trial name
- NCT04167475
- Testing
- Probiotic capsule
- Where
- Ireland
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- PrecisionBiotics Group Ltd.
Healthy Aging, Anti Aging
iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional…
- Trial name
- VITAL (NCT07407894)
- Testing
- Bifidobacterium adolescentis iVS-1
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Gastrointestinal Diseases
The Effects of an Infant Formula Containing Probiotic CECT7210 on Gastrointestinal Health
The purpose of this study is to determine whether an infant formula supplemented with a new probiotic CECT7210, is effective in reducing the incidence of infections, specially the gastrointestinal ones.
- Trial name
- GO-INF (NCT02096302)
- Testing
- Infant Formula with a novel probiotic CECT7210, Standard formula
- Where
- 3 sites in Spain
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Laboratorios Ordesa
Changes in Gut Microbiota, Gut Metabolites, Respiratory Symptoms, and Well-being Index
A Probiotic for Health Outcomes in Short-Term Overseas Travel
With the improvement of living standards, travel has become a common form of leisure. However, travelers often face changes in living environments, dietary habits, and sleep schedules, all of which can impact the gut microbiota…
- Trial name
- NCT07705659
- Testing
- Bifidobacterium longum, Maltodextrin
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- DiproBio (Shanghai) Co., Ltd.
Obesity
Study of Efficacy of a Probiotic and Postbiotic in Overweight and Obese Individuals
The study's main objective is to investigate the effect of a probiotic (live bacteria), postbiotic (heat-treated bacteria) on obesity parameters.
- Trial name
- Obelix (NCT05440630)
- Testing
- Probiotics, Postbiotic
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Safety Issues
Safety Evaluation of Lactobacillus Salivarius AP-32 and Bifidobacterium Animalis Subsp. Lactis CP-9 in Healthy Infants.
This is a three-arm, double-blind, placebo-controlled study to investigate the safety of Lactobacillus salivarius AP-32 and Bifidobacterium animalis subsp. lactis CP-9 used individually in healthy infants.
- Trial name
- NCT04140604
- Testing
- Lactobacillus salivarius AP-32, Bifidobacterium animalis subsp. lactis CP-9
- Where
- Taiwan
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hsieh-Hsun Ho
Gastrointestinal, Gut Health
Consumer Health Study Aims to Evaluate the Safety, Tolerability and Impact of ED02 Probiotic Supplement on Gastrointestinal Outcomes
The Study Team identified Bifidobacterium pseudocatenulatum ED02 as a safe and effective probiotic strain isolated from a healthy human donor.
- Trial name
- NCT07423897
- Testing
- Bifidobacterium pseudocatenulatum
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Functional Constipation
Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation
This prospective, two-arm (parallel groups), double-blind, randomized, placebo-controlled, multi-center clinical trial will investigate the effects of an 8-week Bifidobacterium lactis HN019 supplementation on stool frequency and…
- Trial name
- BifidoDigest (NCT04231162)
- Testing
- Active product, Control product
- Where
- 4 sites in France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Danisco
Obesity, Overweight and Obesity
Investigation of the Effects of a Bifidobacterium Breve Strain on Fat Loss in Healthy Adults
Overweight has become a critical issue in North America and the market value of weight loss products is expected to rise as the population becomes more health-conscious and aware of the risks associated with excess body weight.
- Trial name
- NCT04677738
- Testing
- B. breve strain
- Where
- Canada
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Morinaga Milk Industry Co., LTD
Antibiotic-associated Diarrhea
The Efficacy of a Probiotic for Antibiotic Associated Gastrointestinal Symptoms
This study evaluates the effect of a multistrain probiotic on gastrointestinal (GI) complaints and diarrhoea in subjects receiving short-term antibiotic (AB) treatment
- Trial name
- PANDA (NCT05845073)
- Testing
- Probiotic
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Intestinal Microbiota
Research on the Role of Probiotics in Human Intestinal Health
Evaluate the efectiveness and safety of Bifidobacterium bifidum BBi32 as a food supplement compared to a placebo in improving intestinal andimmune functions in healthy adults.
- Trial name
- NCT06886711
- Testing
- Probiotic
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Functional Constipation
The Efficacy of a Probiotic for Functional Constipation (FC)
Investigate the effect of a probiotic (live bacteria) in individuals with functional constipation.
- Trial name
- SLOG (NCT06083311)
- Testing
- Probiotic
- Where
- Germany
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Adults, GLP-1
Impact of Probiotic (UltraFlora® Triplebiotic) on Weight Evolution on People After Discontinuation of GLP-1 Treatment.
This is a randomized, double-blind, double arm study involving 128 participants who will undergo a total participation period of 12 weeks.
- Trial name
- NCT07209046
- Testing
- UltraFlora® Triplebiotic
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Influenza
Bifidobacterium Lactis HN019 Supplementation for Prevention of Influenza Infection in Healthy Adults
To determine if prophylactic supplementation with B. lactis HN019 reduces the risk of developing physician- and laboratory-confirmed influenza infection at any time during the 12-week supplementation period.
- Trial name
- NCT01258842
- Testing
- Bifidobacterium lactis HN019
- Where
- 2 sites in United States
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Overweight, Obesity
Effect of Study Probiotics on Body Fat Mass in Overweight and Obese Individuals Following Healthy Lifestyle Intervention
A randomized, double-blind, placebo-controlled, multi-center, parallel group study on overweight and obese individuals following healthy lifestyle consisting of calorie-reduced diet (20% calorie restriction) and increase in daily…
- Trial name
- QLSlimCapHL (NCT03934229)
- Testing
- Daily intake of study product
- Where
- 7 sites in France, Spain
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Danisco France SAS