Clinical trials: Bilateral
Geographic Atrophy
A Multicenter, Proof-Of-Concept Study Of Intravitreal AL-78898A In Patients With Geographic Atrophy (GA) Associated With Age-Related Macular Degeneration (AMD)
The purpose of this study was to to demonstrate superiority of AL-78898A intravitreal (IVT) injections compared to sham injections by assessing mean geographic atrophy (GA) lesion size change from baseline at Month 12.
- Trial name
- NCT01603043
- Testing
- Al-78898A
- Volunteers
- 10 people
- Sponsor
- Alcon Research
Blepharitis
Sterile Plant-Based Gauze for Eyelid Hygiene in Anterior Blepharitis
The goal of this clinical trial is to learn whether a sterile gauze containing natural plant extracts can lower the number of bacteria on the eyelid margin in people with bilateral anterior blepharitis.
- Trial name
- BLEPH-GAUZE (NCT07759180)
- Testing
- Plant-Based Sterile Eyelid Gauze, Sterile Cotton Gauze Moistened with Saline Solution
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Azienda Ospedaliera OO.RR. S. Giovanni di Dio e Ruggi D'Aragona
Vestibular Diseases
Covert-saccades, Dynamic Visual Acuity and Quality of Life
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Trial name
- COSQOL (NCT02753179)
- Testing
- Head Impulse Tests, Dynamic visual acuity Test (DVAT), VEMPs & VEMPo
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Pain, Postoperative, Analgesia
Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery
Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and…
- Trial name
- NCT07736989
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Bahçeşehir University
Cataract
Visual Outcomes After Cataract Surgery: Multifocal AcrySof® IQ ReSTOR® Intraocular Lenses Versus Monofocal Intraocular Lenses
The purpose of this study is to assess and compare visual outcomes of the AcrySof® IQ ReSTOR® +3.0 D intraocular lens (IOL) to a commercially available monofocal IOL in cataract patients.
- Trial name
- NCT01290068
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL, Monofocal IOL
- Volunteers
- 208 people
- Sponsor
- Alcon Research
Cataract, Presbyopia
Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery
Interventional, Multicentre, controlled, randomized, single blind, twoarmed non-inferiority trial
- Trial name
- NCT03060954
- Testing
- MINI WELL READY ®, FINE VISION®
- Where
- 2 sites in France
- Volunteers
- 8 people
- Sponsor
- SIFI SpA
Sciatic Leg Pain
Neurodynamic Study
Sciatica is a debilitating and costly condition. Prognostically, patients presenting with leg pain often have a poor recovery and some go onto have spinal surgery.
- Trial name
- NCT03144362
- Testing
- Bilateral Sliding Techniques, Unilateral Sliding Techniques
- Where
- United Kingdom
- Volunteers
- 33 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) occurs in 5% to 10% of all women of reproductive age and 50% of women who present with sub-fertility due to anovulatory infertility .
- Trial name
- NCT05756023
- Testing
- the pregnancy rate at IVF / ICSI cycles
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Egymedicalpedia
Pancreatic Neoplasms
Randomized, Controlled Trial of Endoscopic Ultrasound-Guided Bilateral Celiac Plexus Neurolysis vs Celiac Ganglia Neurolysis to Control Pain in Inoperable Pancreatic Cancer Patients With Inadequate Pain Control by Pain Killer
Pancreatic cancer related pain can be difficult to control, even with high doses of narcotics, whose adverse effects may further impair quality of life.
- Trial name
- NCT02220062
- Testing
- EUS-CPN, EUS-CGN
- Volunteers
- 166 people
- Sponsor
- Samsung Medical Center
Bipolar Disorder
Deep Brain Stimulation (DBS) for Treatment Resistant Bipolar Disorder
Hypothesis to be tested: Bilateral Deep Brain Stimulation to the Nucleus Accumbens is associated with clinically and statistically significant improvement in patients with treatment resistant bipolar disorder.
- Trial name
- DBS-BIPO (NCT01372722)
- Testing
- DBS Activa PC systems Medtronic, DBS, Activa PC systems Medtronic
- Where
- Germany
- Sponsor
- University Hospital, Bonn
Amputation, Traumatic
Changes in Trans Tibial Amputee Running Asymmetry During Prolonged Effort
The purpose of this study is to determine the effect of prolonged effort in long distance running on the biomechanical bilateral asymmetry in the lower limbs of trans tibial amputee running with running specific prosthesis.
- Trial name
- NCT02601456
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Cataract
Accommodation Measurements After Bilateral Implantation of an Aspheric Accommodating Lens and Monofocal Aspheric Lenses
The objective of this study is to demonstrate the correlation of near vision and changes in higher order aberrations following lens extraction and to characterize the defocus curves of Crystalens® AO™ intraocular lens (IOL)…
- Trial name
- NCT01241279
- Testing
- Crystalens AO, SoftPort LI61AO
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Bausch & Lomb Incorporated
Hiatal Hernia, GERD
Laparoscopic Total Left-sided Surgical Approach Versus Traditional Bilateral Surgical Approach for Hiatal Hernia
Background: In China, guidelines for the treatment of hiatal hernia (HH) are lacking. Furthermore, efficacy and safety assessments of surgical approaches for HH and for the protection of the vagus nerve and organ function are…
- Trial name
- NCT06828627
- Testing
- TLSA, TBSA
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Beijing Friendship Hospital
Clubfoot, Prenatal Disorder
CGH Array in Bilateral Clubfoot
In prenatal diagnosis of isolated bilateral clubfoot our team propose genetic analysis: a CGH-array. We want to study the rate of aberrations in these cases.
- Trial name
- NCT04737083
- Testing
- CGH array
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Pain Treatment, Robotic Assisted Laparoscopic Surgery
Bilateral Dual Transversus Abdominis Plane Block for Robotic Assisted Laparoscopic Surgery
To evaluate the effects of bilateral dual transversus abdominis plane block on postoperative pain after robotic assited laparoskopic surgery and measure the plasma-level of ropivacain after the bilateral dual transversus…
- Conditions
- Pain Treatment, Robotic Assisted Laparoscopic Surgery, Bilateral Dual Transversus Abdominis Plane Block
- Trial name
- NCT01760161
- Testing
- Ropivacaine, Isotonic potassium chloride
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Aalborg University Hospital
Anesthesia; Adverse Effect, Spinal and Epidural
Comparative Study Between Bilateral and Unilateral Spinal Anaesthesia
The purpose of this study is to compare unilateral spinal anesthesia using hyperbaric Prilocaine with "classical bilateral spinal anesthesia" using plain Prilocaine according to block characteristics and quality of micturition…
- Trial name
- NCT01877356
- Testing
- bilateral spinal anesthesia, unilateral spinal anesthesia
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- University Hospital, Antwerp
Stroke, Acute
Evaluation of the SONAS® Ultrasound Device for the Assessment of Bilateral Cerebral Perfusion in Subjects With Acute Stroke
The purpose of this clinical investigation is to determine the safety and feasibility of detecting acoustic signals related to blood supply in subjects with acute large vessel occlusion (LVO) stroke by using the SONAS® device.
- Trial name
- NCT03897153
- Testing
- SONAS® Ultrasound Device
- Where
- 2 sites in Austria, Germany
- Volunteers
- 20 people
- Sponsor
- Burl Concepts, Inc.
Major Depressive Disorder
Treatment of Severe Depressive Illness by Targeted Brain Surgery
This study will report on the outcome of a clinical program, operational since 1998, that has used surgery targeting an emotional pathway in the brain in the treatment of severe depressive illness that has failed to respond to…
- Trial name
- NCT01101373
- Where
- Canada
- Sponsor
- University of British Columbia
IOL
Clinical Outcomes of Patients with a Light Adjustable Lens (LAL) in At Least One Eye
To collect data on bilateral pseudophakic patients implanted with the RxSight Light Adjustable Lens (LAL) in at least one eye
- Trial name
- NCT06016231
- Testing
- Light Adjustable Lens
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Bucci Laser Vision Institute
Parkinson Disease
Deep Brain Stimulation (DBS) Frequency Effects on Gait in Parkinson's Disease(PD)
In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking.
- Trial name
- NCT00993291
- Testing
- Frequency change to 60 Hz, Frequency change to 130 Hz
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University