Clinical trials: Bilateral Cataracts
Cataract
Randomized Trial of Aspirin and Cataracts in U.S. Physicians
To determine whether 325 mg of aspirin taken on -alternate days reduces the risk of developing cataract among male U.S. physicians who were aged 40 to 84 in 1982.
- Trial name
- NCT00000157
- Testing
- Aspirin
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Cataract, Aphakia - Lens Capsule Present
Visual Adaptation and Quality of Life After Different IOL Implantation Strategies
This longitudinal observational study aims to evaluate long-term visual adaptation trajectories, optical quality, and patient-reported outcomes in age-related cataract patients following bilateral implantation of multifocal or…
- Trial name
- MMAQ-IOL (NCT07740590)
- Testing
- Bilateral Bifocal IOL Implantation, Bifocal and EDOF IOL Mix-and-Match Implantation, Bifocal and Monofocal IOL Mix-and-Match Implantation
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sichuan Academy of Medical Sciences
Bilateral Cataract
Cost-effectiveness of ISBCS vs. DSBCS
The purpose of this study is to evaluate the effectiveness and costs of immediately sequential bilateral cataract surgery (ISBCS) compared to delayed sequential bilateral cataract surgery (DSBCS) in order to determine whether…
- Trial name
- NCT03400124
- Testing
- ISBCS, DSBCS
- Where
- Netherlands
- Volunteers
- 858 people
- Sponsor
- Maastricht University Medical Center
Correction Vision Surgery, Cataract Surgery
Clinical Outcomes of Bilateral Clareon Vivity in Post-Refractive Patients
Millions of people have undergone laser vision correction surgery and are motivated to continue with spectacle independence as they develop presbyopia (gradual loss of your eyes' ability to focus on nearby objects)and cataract.
- Trial name
- NCT06924944
- Testing
- cataract surgery
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Utah Eye Centers
Cataract Bilateral, Bilateral Cataracts
Medico-economic Evaluation of Immediately Sequential Bilateral Cataract Surgery Compared With Delayed Sequential Cataract Surgery in France
Cataracts are defined as opacification of all or part of the crystalline lens, resulting in reduced vision. It is a common disease in France, affecting more than one in five people over the age of 65, and almost two in three over…
- Conditions
- Cataract Bilateral, Bilateral Cataracts, Bilateral Cataract
- Trial name
- SIMCAT (NCT06737562)
- Testing
- Immediatly sequential bilateral cataract surgery, Delayed sequential bilateral cataract surgery
- Where
- 4 sites in France
- Volunteers
- 242 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Cataracts
A Comparison of Prophylactic Antibacterial Efficacy of Besivance vs. VIGAMOX Prior to Cataract Surgery
To compare antibacterial efficacy of Besivance versus VIGAMOX for decreasing bacteria of the conjunctiva and lid margins in cataract patients prior to surgery after both 1 hour and 3 days of treatment.
- Trial name
- NCT01296542
- Testing
- Moxifloxacin Ophthalmic, Besifloxacin Ophthalmic
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bucci Laser Vision Institute
Cataract
Combined EDOF / Trifocal
The purpose of this study is to obtain postoperative visual performance data of patients with bilateral implantation of the AT LARA IOL or the AT LARA implanted in the dominant eye and AT LISA tri implanted in the other eye.
- Trial name
- NCT05462067
- Testing
- AT LARA IOL, AT LISA Tri IOL
- Where
- 4 sites in Denmark, Germany and 1 more
- Volunteers
- 72 people
- Sponsor
- Carl Zeiss Meditec AG
Cataracts, Corneal Edema
Study of Difluprednate vs. Prednisolone Acetate on Visual Acuity, and Corneal Edema Following Cataract Surgery.
The purpose of this clinical research study is to investigate the efficacy of predosing patients undergoing cataract surgery with the potent corticosteroid difluprednate ophthalmic emulsion 0.05% compared to prednisolone acetate…
- Conditions
- Cataracts, Corneal Edema, Retinal Structural Change, Deposit and Degeneration, Visual Acuity Reduced Transiently
- Trial name
- NCT01244334
- Testing
- Difluprednate ophthalmic emulsion 0.05%, Prednisolone acetate 1%
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- Edward J. Holland
Cataract
Visual Outcomes After Bilateral Surgical Cataract Phacoemulsification: AcrySof Toric IOL Implantation Compared to Monofocal IOL Implantation
The objectives of this study are to assess and compare bilateral uncorrected distance visual acuity and distance spectacle independence post bilateral implantation of AcrySof Toric Intraocular Lenses (IOLs) and monofocal IOLs.
- Trial name
- NCT01192321
- Testing
- Toric T3 - T9, Monofocal
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1802 (NCT03688425)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Philippines
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataracts, Alzheimer's Disease
Cataract Removal and Alzheimer's Disease
Two very common aging-related diseases in older adults are Alzheimer's disease (AD) and cataracts. In elderly adults, these two diseases frequently occur in the same person.
- Trial name
- NCT00921297
- Testing
- Immediate Cataract Surgery
- Where
- 2 sites in United States
- Volunteers
- 122 people
- Sponsor
- University Hospitals Cleveland Medical Center
Cataract
Clinical Outcomes With Bilateral Implantation of Odyssey IOLs
This study is a single center, ambispective study of visual outcomes after successful bilateral cataract surgery. Subjects will be assessed at least 3 months postoperatively at a single visit.
- Trial name
- NCT06550375
- Testing
- TECNIS Odyssey IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mann Eye Institute
Cystoid Macular Edema Following Cataract Surgery, Bilateral
Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery
The purpose of this study is to compare effects of preoperative and postoperative use of topical ketorolac tromethamine 0.4% versus placebo in uncomplicated cataract surgery.
- Trial name
- NCT01542190
- Testing
- Ketorolac Tromethamine
- Where
- 2 sites in Brazil
- Volunteers
- 80 people
- Sponsor
- University of Campinas, Brazil
Age Related Cataracts
The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract
The study objectives were: To evaluate the efficacy of EDTA 1.3% and 2.6% ophthalmic solution (C-KAD) in improving visual function as assessed by contrast sensitivity; To evaluate the safety and tolerability of two doses of EDTA…
- Trial name
- NCT06365762
- Testing
- EDTA Ophthalmic Solution 2.6%, EDTA Ophthalmic Solution 1.3%
- Where
- 6 sites in United States
- Volunteers
- 111 people
- Sponsor
- Livionex Inc.
Presbyopia, Near Vision
The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Daily Living
Primary objective of this study is to identify the optimal task lighting conditions (in terms of light intensity and light temperature) for 10 activities of daily living (ADLs) that require near or intermediate vision acuity in a…
- Conditions
- Presbyopia, Near Vision, Reading, Daily Activities
- Trial name
- NCT05359380
- Testing
- ADL performance
- Where
- Greece
- Volunteers
- 75 people
- Sponsor
- Democritus University of Thrace
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Cataracts
Laser Cataract Surgery With the Femtosecond Laser Technology
The purpose of this study is to prove the efficacy and safety of the Femtosecond laser to create a clear corneal incision during cataract surgery.
- Trial name
- NCT01382823
- Testing
- Femtosecond Laser
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Innovative Medical
Cataract
AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study
The objective of this study is to assess the spectacle independence of patients receiving the AcrySof® Panoptix® Intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04126187
- Testing
- Panoptix
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Gainesville Eye Associates
Cataract
Retrospective Patient Satisfaction Survey in Subjects With Tecnis Intra Ocular Lenses and Cataracts Surgery
Define what factors correlate with higher degrees of patient satisfaction and dissatisfaction among patients who have recently undergone cataract surgery.
- Trial name
- NCT01946581
- Testing
- Cataract Surgery
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- MDbackline, LLC
Cataracts
A Real-World Registry to Investigate the Performance of LenSx® Laser in Chinese Patients
The purpose of this study is to investigate the performance of LenSx® Laser in femtosecond laser-assisted cataract surgery (FLACS) in real-world medical practice in Chinese patients.
- Trial name
- NCT02396719
- Testing
- LenSx® Laser
- Where
- China
- Volunteers
- 1,541 people
- Sponsor
- Alcon Research