Clinical trials: Bilateral Cataracts
Multifocal Contact Lenses
Multifocal Contact Lenses vs Bifocal Spectacles for Congenital Cataracts
In this study, the investigators provide participants who had congenital cataract the multifocal contact lenses and bifocal spectacles in the purpose of seeking out a better way to make a definite diagnosis with high efficiency…
- Trial name
- NCT03260764
- Testing
- short term Multifocal Contact Lenses, short term Bifocal Spectacles, long term Multifocal Contact Lenses
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sun Yat-sen University
MCS vs ReLACS, Pain Perception Postoperative
Manual Immediately Sequential Bilateral Cataract Surgery (M-ISBCS) vs Refractive Laser-Assisted Immediately Sequential Bilateral Cataract Surgery (ReLA-ISBCS)
The focus of this study is to assess the differences in patient perceptions of pain undergoing cataract surgery by using the Refractive Laser-Assisted Cataract Surgery (ReLACS) technique compared to the standard Manual Cataract…
- Conditions
- MCS vs ReLACS, Pain Perception Postoperative, Early Anesthesia vs Standard Anesthesia, Immediately Sequential Bilateral Cataract Surgery
- Trial name
- NCT05480839
- Testing
- M-IBCS, ReLA-IBCS Early, ReLA-ISBCS
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists
Cataract Senile
Evaluation of the Extended Depth of Focus After Bilateral Implantation of Hydrophobic IOLs
This will be a prospective observational, ethics committee approved study where patients undergoing routine cataract surgery will have bilateral implantation of the intraocular lens (LuxSmart, Bausch \& Lomb).
- Trial name
- LuxSmart (NCT04523558)
- Testing
- Implantation of LuxSmart hydrophobic IOLs (Bausch + Lomb) in both eyes
- Where
- Czechia
- Volunteers
- 33 people
- Sponsor
- Gemini Eye Clinic
Cataract, Intraocular Lens
Comparison on Outcomes of Four IOLs in Patients With Cataracts
The objective of this study was to compare the objective visual outcomes and subjective fuctional vision of four different intraocular lens (IOL) in patients underwent cataracts surgery. This was a retrospective study.
- Conditions
- Cataract, Intraocular Lens, Visual Outcomes
- Trial name
- NCT06590272
- Testing
- TECNIS PCB00 intraocular lens, HumanOptics Diff-Aay intraocular lens, TECNIS Symfony ZXR00 intraocular len
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Shanghai 10th People's Hospital
Age-Related Macular Degeneration, Cataract
Age-Related Eye Disease Study (AREDS) Follow-Up
This study is a 5-year extension of the AREDS protocol, in which investigators followed the natural course of age-related macular degeneration (AMD) and cataracts.
- Trial name
- NCT00594672
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- National Eye Institute (NEI)
Optical Biometer, Cataracts
Evaluation of Three SS-OCT and One PCI Optical Biometers in Eyes With Dense Cataract
To describe and compare the acquisition rate between different biometers in eyes with advanced cataracts
- Trial name
- BIO-CAT-DENSA (NCT05239715)
- Testing
- Ocular biometry
- Where
- Spain
- Volunteers
- 51 people
- Sponsor
- OFTALVIST (Oftalmología Vistahermosa S.L)
Apheresis
Prevalence and Risk of Cataracts in Granulocyte Donors
This study will investigate whether people who donate granulocytes (a type of white blood cell) by leukapheresis are at increased risk of developing cataracts (changes in the lens of the eye that can impair vision).
- Trial name
- NCT00042627
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- National Eye Institute (NEI)
Cataract
Evaluation of Vision After Vivity IOL Implantation With a Target of Slight Myopia in the Non-dominant Eye
The objective is to assess binocular distance-corrected near (40 cm) visual acuity of patients after uneventful cataract surgery with bilateral implantation of the AcrySof® Vivity Intraocular lens (IOL) when the non-dominant eye…
- Trial name
- NCT04482439
- Testing
- Vivity Extended Depth of Focus intraocular lens (IOL)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Newsom Eye & Laser Center
Cataract
Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL
Comparison of postoperative visual acuity and spectacle independence between the Tecnis Multifocal Intraoculer Lens (IOL) and the crystalens Accommodating IOL
- Trial name
- NCT01275118
- Testing
- Tecnis Multifocal IOL, crystalens Accommodating IOL
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Mark Packer, MD, FACS
Cataract, Presbyopia
Multifocal Intraocular Lens x Monovision x Hybrid Monovision After Bilateral Cataract Surgery
To compare refractive outcomes and patient's visual quality after bilateral cataract surgery when implanting multifocal intraocular lens, monofocal with monovision or hybrid monovision.
- Trial name
- NCT02595177
- Testing
- Cataract surgery with intraocular lens implantation.
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cataracts
Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo
To evaluate the safety and efficacy of Nepafenac 1 mg/ml Eye Drops, Suspension, compared to Placebo and Ketorolac Trometamol 5 mg/ml Eye Drops, Solution for the prevention and treatment of ocular inflammation and ocular pain…
- Trial name
- NCT00405730
- Testing
- Nepafenac 1mg/ml eye drops, suspension, Ketorolac Trometamol 5 mg/ml eye drops, solution, Nepafenac vehicle eye drops
- Where
- France
- Volunteers
- 227 people
- Sponsor
- Alcon Research
Cataracts
Accuracy of the Galilei Analyzer to Calculate the Effective Corneal Power After Corneal Refractive Surgery
The purpose of this study is to determine the accuracy of the Galilei corneal analyzer to calculate the effective corneal power (keratometry, corneal curvature) in patients who have undergone both corneal refractive surgery and…
- Trial name
- Galilei (NCT00934804)
- Testing
- Galilei dual Scheimpflug analyzer
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Cataract
Visual Function After Implantation of Bilateral AcrySof® Toric Natural Intraocular Lens
The purpose of this study is to evaluate the effect that placement and power of the AcrySof Toric has on post-operative visual acuity and spectacle independence for distance vision.
- Trial name
- NCT00760487
- Testing
- AcrySof Toric IOL
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Cataract, Presbyopia
A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs
Since the introduction of intraocular lenses (IOL) in the treatment of cataract, the postoperative accommodative loss of the human eye has been a trending topic.
- Trial name
- NCT03117426
- Testing
- SYMFONY IOL, AT LISA tri 839MP IOL
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Cataracts
AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric Intraocular Lens (IOL) Clinical Study in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Models SND1T3, SND1T4, SND1T5, and SND1T6 when implanted to replace the natural lens in Japanese cataract…
- Trial name
- NCT01323777
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL
- Where
- 2 sites in Japan
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Cataract
Prospective Clinical Trial of the LensAR Laser System
The LensAR Laser System is used to create an opening in the anterior capsule of the lens and fragments the cataractous lens. The study will evaluate clinical outcomes compared to the contra-lateral eye treated with conventional…
- Trial name
- NCT01014702
- Testing
- LensAR Laser System, Conventional phacoemulsification
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- LensAR Incorporated
Cataracts
User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL
Prospective collection of data from medical records, multicenter, post-market clinical follow-up study.
- Trial name
- NCT06005675
- Testing
- Intervention
- Where
- 4 sites in United States
- Volunteers
- 44 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Extended Depth-of-Focus Intraocular Lens, Cataract
Visual and Patient-Reported Outcomes After Bilateral Non-Diffractive EDOF IOL Implantation
This study evaluates visual outcomes and patient-reported satisfaction following bilateral cataract surgery using a non-diffractive extended depth-of-focus (EDOF) intraocular lens (AcrySof IQ Vivity).
- Conditions
- Extended Depth-of-Focus Intraocular Lens, Cataract, Visual Acuity
- Trial name
- EDOF-Visual (NCT07457216)
- Testing
- AcrySof IQ Vivity EDOF Intraocular Lens
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Benha University
Cataracts
A Multicenter, Observational, Single Arm Study of the TECNIS Presbyopia-correcting Intraocular Lens
Ambispective post-market data collection on visual symptoms, patient satisfaction and surgeon experience with the TECNIS PC IOL.
- Trial name
- NCT06250322
- Testing
- Intervention
- Where
- 20 sites in Australia, Austria and 6 more
- Volunteers
- 307 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.