Clinical trials: Bilateral Cataracts
Cataract
Outcomes of Bilateral Implantation of an Enhanced Monofocal Intraocular Lens
To evaluate and compare the visual outcomes of an enhanced monofocal intraocular lens (IOL) with two different monofocal IOLs in patients scheduled for bilateral cataract surgery.
- Trial name
- RCT_ICB00 (NCT06118944)
- Testing
- ICB00 IOL, ZCB00 IOL, CNA0T0 IOL
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- University of Trieste
Cataract
Assessment of Visual Performance With Virtual Reality After Cataract Surgery
The proposed randomized clinical trial aims to compare visual performance, measured using VR simulations, in cataract patients implanted either with bilateral trifocal IOL or bilateral monofocal IOL with monovision.
- Trial name
- NCT06015334
- Testing
- cataract surgery with implantation of intraocular lens
- Volunteers
- 114 people
- Sponsor
- The University of Hong Kong
Cataracts, Retina Surgery
Eye Drop Application Monitor, Pilot Study
The purpose of this study is to determine if an eye drop video monitoring device can accurately assess (as compared to a patient's own log or a proprietary software) the exact amount and time of eye drop delivery to a patient's…
- Conditions
- Cataracts, Retina Surgery, Glaucoma, Any Condition That Requires Ophthalmic Drops
- Trial name
- NCT02639845
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Alexander Eaton
Cataracts
Comparison of the Effectiveness of Povidone-iodine in Reducing Conjunctival Bacterial Load Prior to Cataract Surgery in Patients Treated With a Lidocaine Gel Dilating Formulation Versus Eye Drops: A Randomized Controlled Trial
The eye contains a lens that focuses light. A clouding of the lens is known as a cataract. Cataracts decrease vision. The treatment for cataracts is cataract surgery.
- Trial name
- NCT01898728
- Testing
- topical povidone-iodine after premedication with topical liquid eye drops, topical povidone-iodine after premedication with topical gel
- Where
- Canada
- Volunteers
- 101 people
- Sponsor
- McMaster University
Primary Open Angle Glaucoma and Cataracts
A Clinical Trial of Phacoemulsification Versus Phacoemulsification & the iStent Implantation in POAG Patients
This was a prospective, double-masked, 15-month clinical trial comparing efficacy of phacoemulsification alone to combined phacoemulsification and implantation of the iStent® trabecular micro-bypass stent in patients with primary…
- Trial name
- NCT00847158
- Testing
- phacoemulsification alone, iStent Trabecular Micro-Bypass Stent
- Volunteers
- 36 people
- Sponsor
- University of Turin, Italy
Cataract
Visual Function With Contralateral AcrySof® ReSTOR® Aspheric SN6AD1 and SN6AD3
The objective of this study is to prospectively evaluate the visual parameters in a series of patients after phacoemulsification cataract surgery in a series of patients bilaterally implanted with the AcrySof® ReSTOR® Aspheric…
- Trial name
- NCT00710905
- Testing
- AcrySof ReSTOR Aspheric IOL models SN6AD1 and SN6AD3
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Cataracts
Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens
Prospective, multicenter, bilateral, interventional, controlled, masked (sponsor, subjects, and evaluators), randomized clinical trial.
- Trial name
- NCT06377514
- Testing
- Test IOL Model DEN00V, Control IOL Model DCB00
- Where
- 9 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Intraocular Pressure, Cataracts Senile
Intraocular Pressure Variation by Pneumatic Tonometer Before and After Phacoemulsification
The objective of this study is to evaluate the IOP variation before and 30 days after performing phacoemulsification through pneumatic tonometry, in addition to evaluating the factors possibly related to this variation.
- Trial name
- IPOFACO (NCT03016507)
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- VER Excelência em Oftalmologia
Bilateral Cataract, Charles Bonnet Syndrome
Patient Reported Visual Satisfaction Following Same Day or Delayed Bilateral Cataract Surgery
Cataract is currently the leading cause of visual impairment worldwide with age being the most common cause of lenticular opacification.
- Trial name
- CatquestCBS (NCT05069753)
- Testing
- Immediate sequential bilateral cataract surgery (ISBCS), Delayed sequential bilateral cataract surgery (DSBCS)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Bilateral Cataract, Astigmatism
Non-comparative Trial Following Participants Implanted Bilaterally With Mini WELL Toric Ready Intraocular Lens for 6 Months After the Second Eye Implant (FUSION)
This is a multicenter, non-comparative trial following participants implanted bilaterally with the Mini WELL Toric Ready intraocular lens (IOL) for 6 months after the second eye implant.
- Trial name
- FUSION (NCT03861351)
- Testing
- Mini WELL Toric Ready intraocular lens
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 58 people
- Sponsor
- SIFI SpA
Congenital Cataract Polar Posterior
Visual Function in Pediatric Patients With Posterior Lens Opacities
Prognostic factors determining visual outcomes in patients with posterior polar cataracts and posterior lenticonus are largely unknown.
- Trial name
- NCT05207007
- Testing
- Phacomulsification lens removal cataract surgery with Intraocular lens(IOL) implantation
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Sun Yat-sen University
Cataracts, Astigmatism
Post Approval Study of the AcrySof® IQ Toric Intraocular Lens (IOL) Models SN6AT6-SN6AT9
The purpose of this study is to evaluate the use of toric high cylinder power intraocular lenses in a larger population in clinical practice and assure the continued safety of these approved devices.
- Trial name
- NCT01601665
- Testing
- SN6AT6 Intraocular Lens, SN6AT7 Intraocular Lens, SN6AT8 Intraocular Lens
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- Alcon Research
Fuchs Endothelial Corneal Dystrophy, Cataract
Comparison of Outcomes Between Femtosecond Laser-Assisted and Conventional Phacoemulsification in Fuchs Endothelial Corneal Dystrophy Patients With Cataracts
The goal of this observational study is to compare the mid- to long-term efficacy of femtosecond laser-assisted cataract surgery (FLACS) and conventional phacoemulsification surgery (CPS) in patients with moderate to severe…
- Trial name
- NCT06966167
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to evaluate visual and refractive parameters in a series of subjects bilaterally implanted with presbyopia-correcting intraocular lenses (IOLs) during cataract surgery.
- Trial name
- NCT01257217
- Testing
- AcrySof® IQ ReSTOR® +3.0 D Multifocal IOL Model SN6AD1, AcrySof® IQ ReSTOR® +3.0 D Multifocal Toric IOL Model SND1TT, Acri.LISA® 366D IOL
- Volunteers
- 31 people
- Sponsor
- Alcon Research
Cataract
Risk of Radiation-induced Cataracts Among Interventional Cardiology Staff
The goal of the present study is to evaluate the prevalence of radiation-associated lens opacities among interventional cardiology staff members (such as physicians, technicians, and nurses) and determine its association with…
- Trial name
- IC-CATARACT (NCT02837562)
- Testing
- Slit lamp eye examination
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Congenital Cataract
Congenital Cataract Morphological Classifications
Photography is considered as one of the most important means to promote evidence-based medical practice in pediatric ophthalmology.This study is to investigate the feasibility of congenital cataract morphological classifications…
- Trial name
- NCT02748031
- Testing
- slit-lamp-adapted anterior segmental photography
- Where
- China
- Volunteers
- 1,050 people
- Sponsor
- Sun Yat-sen University
Hyperalgesia
Effect of Gabapentin on Pain of the Second Cataract Surgery
Gabapentin pretreatment may reduce hyperalgesia occurring at the second surgery in serial, bilateral cataract surgery.
- Trial name
- NCT02127853
- Testing
- gabapentin
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Cataracts, Meibomian Gland Dysfunction (MGD)
A Post-Market Evaluation of LipiFlow Treatment in Cataract Surgery Practice
This is a post-market, prospective, randomized, multi-center, bilateral, open-label, cross-over, comparative clinical study. Study group will undergo preoperative LipiFlow treatment and Control group will not receive preoperative…
- Trial name
- NCT03708367
- Testing
- LipiFlow Thermal Pulsation System
- Where
- 5 sites in United States
- Volunteers
- 117 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataracts, Presbyopia
Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens
The purpose of this study is to evaluate the safety and performance of the SBL-3 intraocular lens.
- Trial name
- NCT02487160
- Testing
- SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
- Where
- 13 sites in United States
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract
Visual Function After Implantation of Bilateral AcrySoft ReSTOR Aspheric IOL
This study will involve up to 20 bilateral patients per surgeon. Patients will be assessed pre-operatively, and at subsequent visits (following the implantation of the intraocular lens in the second eye) at 1 week, 1 month, 3…
- Trial name
- NCT00934622
- Testing
- AcrySof® ReSTOR® Aspheric IOL
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research