Clinical trials: Bile Duct Disease
Bile Duct Diseases
Infection Control in ERCP Using a Duodenoscope With a Disposable Cap
1. Background \& Rationale Over 650,000 endoscopic retrograde cholangio-pancreatography (ERCP) procedures are performed annually in the United States alone.
- Trial name
- ICECAP (NCT04040504)
- Testing
- ERCP procedure with Pentax ED-34i10T2 Duodenoscope with Disposable Cap (DEC), ERCP procedure with Pentax ED-34i10T Duodenoscope
- Where
- Canada
- Volunteers
- 520 people
- Sponsor
- University of Calgary
Inoperable Disease, Bile Duct Cancer
CH-EUS in Diagnosis of Inoperable Bile Duct Tumors
VALIDATION OF THE SUPERIORITY OF CONTRAST ENHANCED ENDOSCOPY TO STANDARD ENDOSCOPY IN THE DIAGNOSIS OF BILE DUCT TUMORS
- Trial name
- NCT05418543
- Testing
- Endoscopic ultrasound with fine needle biopsy
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Institutul Regional de Gastroenterologie & Hepatologie Prof. dr. Octavian Fodor
Bile Duct Diseases, Pancreas Cancer
Trainee Involvement in ERCP Risk Score
The study aims to evaluate factors associated with an increased risk of procedure related adverse events (including tecnical failure) of endoscopic retrograde cholangiopancreatography procedures (ERCP) conducted in a teaching…
- Trial name
- TIERS (NCT04341909)
- Testing
- ERCP
- Where
- Romania
- Volunteers
- 1,283 people
- Sponsor
- Clinical Hospital Colentina
Bile Duct Stricture, Endoscopic Retrograde Cholangiopancreatography
Transparent Cap-assisted SpyGlass for Biliary Stricture
The transparent cap-assisted endoscope has the function of fixing field of view and increasing visual space. It has been widely used in gastrointestinal examination and treatment.
- Conditions
- Bile Duct Stricture, Endoscopic Retrograde Cholangiopancreatography, Biliary Disease, Biliary Tract Neoplasms
- Trial name
- NCT05320497
- Testing
- Transparent cap
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Choledocholithiasis, Bile Duct Neoplasms
Mechanistic Loop Resolution Strategy for Short-type Single Balloon Enteroscopy
Endoscopic retrograde cholangiopancreatography (ERCP) is the current standard technique for the treatment of pancreatobiliary disease. However, ERCP in patients with a surgically altered anatomy (SAA) remains a challenge.
- Conditions
- Choledocholithiasis, Bile Duct Neoplasms, Biliary Tract Diseases, Roux-en-Y Anastomosis
- Trial name
- NCT04847167
- Testing
- Single balloon enteroscopy assisted ERCP using a mechanistic loop resolution strategy group
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Ajou University School of Medicine
Pancreas Cancer, Pancreas Neoplasm
Prognostic Factors in Periampullary Tumors and Cysts
The project aims at analysing prognostic and predictive factors involved in diagnostics and surgical treatment of cysts and tumors in the pancreas and periampullary region using both clinical data and blood and tissue samples for…
- Conditions
- Pancreas Cancer, Pancreas Neoplasm, Pancreas Cyst, Pancreatic Fistula
- Trial name
- NCT05155878
- Where
- Sweden
- Volunteers
- 500 people
- Sponsor
- Umeå University
Alagille Syndrome
A Maralixibat Expanded Access Program for Patients With Cholestatic Pruritus Associated With Alagille Syndrome (ALGS)
An open-label, single-arm, multi-centre program providing treatment access to ALGS patients with cholestatic pruritus in the US.
- Trial name
- NCT04530994
- Testing
- maralixibat
- Where
- 14 sites in United States
- Sponsor
- Mirum Pharmaceuticals, Inc.
Cancer of the Bile Duct
Single Agent Regorafenib in Refractory Advanced Biliary Cancers
The main purpose of this study is to see if regorafenib can help control or decrease cancer size in patients with cancer of the bile duct. Researchers also want to find out if regorafenib is safe and tolerable.
- Trial name
- NCT02115542
- Testing
- Regorafenib
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Bile Duct Disorder, Endocrine Pancreas Disorder
Feasibility of Laryngeal Mask Airway Gastro on Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Pancreas and Bile Duct Disorders
This trial determines the feasibility of Laryngeal Mask Airway Gastro (Laryngeal Mask Airway) when used on patients who are undergoing endoscopic retrograde cholangiopancreatography for pancreas and bile duct disorders.
- Trial name
- NCT03775681
- Testing
- Endoscopic Retrograde Cholangiopancreatography, Interview, Laryngeal Mask Airway
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- M.D. Anderson Cancer Center
Surgery, Biliary Disease
Bile Duct Injury Digestif
Data accumulated from medical record collected from January 2008 until December 2018
- Conditions
- Surgery, Biliary Disease, Bile Duct Injury, Sepsis
- Trial name
- NCT04582240
- Testing
- no intervention
- Volunteers
- 24 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Cholangitis, Liver Cirrhosis, Biliary
Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital
Retrospective study of all patients diagnosed with primary biliary cholangitis during January 2001 to July 2016 at West China Hospital by review of medical records.
- Conditions
- Cholangitis, Liver Cirrhosis, Biliary, Cholestasis, Liver Diseases
- Trial name
- NCT02917408
- Where
- China
- Volunteers
- 769 people
- Sponsor
- Xiaoli Fan
Pancreas Disease, Liver Diseases
Results of Surgical Treatment of the Hepatobiliopancreatic Surgical Unit
The main aims of this study are: 1. - to evaluate post-surgical morbidity and mortality outcomes, following the criteria and the definitions from Claven-Dindo and ISGPS international classifications, of the patients operated by…
- Conditions
- Pancreas Disease, Liver Diseases, Surgical Procedure, Unspecified, Bile Duct Diseases
- Trial name
- HPB (NCT04556019)
- Testing
- Hepatobiliopancreatic surgery
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacion Miguel Servet
Endoscopic Retrograde Cholangiopancreatography, Common Bile Duct Diseases
Double Guidewire Technique Versus Transpancreatic Precut in Patients With Repetitive Unintentional Cannulation of the Pancreatic Duct.
Difficult cannulation of the common bile duct is encountered in about 10%of ERCP procedures. This frequently happens in the form of repeated unintentional cannulation of the pancreatic duct.
- Conditions
- Endoscopic Retrograde Cholangiopancreatography, Common Bile Duct Diseases, Transpancreatic Precut, Precut
- Trial name
- NCT04503200
- Testing
- Double guidewire, Transpancreatic precut
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Cancer
Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions
RATIONALE: Using BG00001 to insert the gene for interferon-beta into a person's pleural cavity may improve the body's ability to fight cancer.
- Trial name
- NCT00066404
- Testing
- recombinant adenovirus-hIFN-beta
- Where
- United States
- Sponsor
- Abramson Cancer Center at Penn Medicine
Biliary Stricture, Pancreas Cancer
Volumetric Laser Endomicroscopy's (VLE) Diagnostic Accuracy Validation Study: Impact on Clinical Management Study
The purpose of this study is to assess the interobserver agreement (IOV) for pancreatico-biliary Volumetric Laser Endomicroscopy (VLE) de-identified clips using the new VLE criteria.
- Conditions
- Biliary Stricture, Pancreas Cancer, Cholangiocarcinoma, Bile Duct Cancer
- Trial name
- VLE-IOV (NCT03951324)
- Testing
- Interobserver agreement or Interrater agreement
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Innovative Digestive Health Education and Research Inc
Lesions of Biliary or Wirsung Ducts, Biliary Tract Diseases
Assessment of Cholangio-pancreatoscopy for the Diagnosis and the Treatment of Biliary and Pancreatic Diseases
The biliary and pancreatic tumors are rare but the prognosis is pejorative. It was difficult to have histology of these tumors as the samples taken during ERCP were performed under " blind " radiology control.
- Conditions
- Lesions of Biliary or Wirsung Ducts, Biliary Tract Diseases, Common Bile Duct Diseases, Pancreatic Duct Disorder
- Trial name
- NCT03190343
- Testing
- cholangio-pancreatoscopy
- Where
- 3 sites in France
- Volunteers
- 67 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Common Bile Duct Stone, Malignant Hepatobiliary Neoplasm
Primary Needle Knife Fistulotomy Versus Conventional Cannulation Method
The aim of this study are to evaluate the feasibility of needle knife fistulotomy (NKF) as an initial procedure for biliary access in patients with biliary disease who are at increased risk for post-endoscopic retrograde…
- Conditions
- Common Bile Duct Stone, Malignant Hepatobiliary Neoplasm, Biliary Stricture, Pancreatic Diseases
- Trial name
- NCT02916199
- Testing
- cannulation of ampulla of Vater
- Where
- 7 sites in South Korea
- Volunteers
- 207 people
- Sponsor
- Gangnam Severance Hospital
Biliary Obstructive Disease Such as Choledocholithiasis, Benign Biliary Stricture
Effectiveness of Prophylactic Antibiotics to Prevent Post Endoscopic Retrograde Cholangio Pancreatography Bacteremia in Biliary Obstruction Patient
Endoscopic retrograde cholangio-pancreatography (ERCP) is advanced endoscopic technique that allows minimally invasive management of biliary and pancreatic disorders.
- Conditions
- Biliary Obstructive Disease Such as Choledocholithiasis, Benign Biliary Stricture, Peri-ampullary Cancer, Bile Duct Cancer Resectable
- Trial name
- NCT02958059
- Testing
- Pacetin® (cefoxitin)
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Yonsei University
Bile Duct Diseases
Impact of Pinaverium Bromide on Bile Duct and Pancreatic Duct Cannulation During Endoscopic Retrograde Cholangiopancreatography
Pinaverium bromide can be used to treat symptoms related to irritable bowel syndrome (IBS) and functional disorders of the biliary tract.
- Trial name
- NCT02882451
- Testing
- pinaverium bromide, Vitamin C
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University