Clinical trials: Biliary Intervention
Malignant Biliary Obstruction, Advanced Pancreatic Cancer and Cholangiocarcinoma
Improving a Bile Duct Drainage Procedure in Patients With Inoperable Cancer Blocking the Bile Ducts: Comparing Two Types of Endoscopically Placed Internal Stents to Prevent Blockage of a Lumen Apposing Metal Stent
This study looks at the best way to treat bile duct blockage in people with advanced cancer that cannot be removed by surgery. A blocked bile duct can cause serious symptoms like yellowing of the skin (jaundice), infection, and…
- Conditions
- Malignant Biliary Obstruction, Advanced Pancreatic Cancer and Cholangiocarcinoma, Inoperable Malignant Biliary Obstruction, Lumen Apposing Metal Stents
- Trial name
- Opti-LAMS (NCT07115420)
- Testing
- Fully covered self expanding metal stent (FCSEMS) within LAMS, Double pigtail stent (DPS) within LAMS
- Where
- New Zealand
- Volunteers
- 100 people
- Sponsor
- Waikato Hospital
Hepatocellular Carcinoma, Primary Liver Cancer
Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms
The purpose of this study is to test the efficacy of a collaborative care intervention to manage cancer-related symptoms and improve health related quality of life in patients diagnosed with hepatobiliary carcinoma.
- Conditions
- Hepatocellular Carcinoma, Primary Liver Cancer, Bile Duct Cancer, Pancreatic Cancer
- Trial name
- CaSSY (NCT01640522)
- Testing
- Collaborative Care, Enhanced usual Care
- Where
- United States
- Volunteers
- 261 people
- Sponsor
- University of Pittsburgh
Common Bile Duct Stone
Common Bile Duct Stones - Natural History and Interventions
The aims of this study were to 1. investigate what measures were taken when common bile duct stones (CBDS) were found intraoperatively in Sweden during the period May 2005 to December 2009 by using data from this population-based…
- Trial name
- NCT01734720
- Volunteers
- 3,828 people
- Sponsor
- Karolinska Institutet
Pancreas Disease, Liver Diseases
Results of Surgical Treatment of the Hepatobiliopancreatic Surgical Unit
The main aims of this study are: 1. - to evaluate post-surgical morbidity and mortality outcomes, following the criteria and the definitions from Claven-Dindo and ISGPS international classifications, of the patients operated by…
- Conditions
- Pancreas Disease, Liver Diseases, Surgical Procedure, Unspecified, Bile Duct Diseases
- Trial name
- HPB (NCT04556019)
- Testing
- Hepatobiliopancreatic surgery
- Where
- Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacion Miguel Servet
Gallstone Disease
Comparing Minilaparotomy and Laparoscopic Cholecystectomy as a Day Surgery Procedure
Minlaparotomy (MC) and laparoscopic cholecystoctomy (LC) are commonly applied surgical techniques for the management of symptomatic gallstone disease and both techiques have shown to be feasible for day surgery.
- Trial name
- NCT01873638
- Testing
- Cholecystectomy
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Kuopio University Hospital
Cholangiocarcinoma, Pancreatic Cancer
T-EUS for Gastrointestinal Disorders: A Multicenter Registry
The purpose of this registry is to record information and evaluate the impact of Endoscopic Ultrasound (EUS) Guided Endoscopic retrograde cholangiopancreatography (ERCP) on the management of pancreatico-biliary disorders.
- Conditions
- Cholangiocarcinoma, Pancreatic Cancer, Bile Duct Cancer, Biliary Stricture
- Trial name
- EUSERCPReg (NCT01522573)
- Testing
- EUS guided ERCP
- Where
- 2 sites in United States, Brazil
- Volunteers
- 1,000 people
- Sponsor
- Weill Medical College of Cornell University
Gastric Cancer, Colorectal Cancer
Effect of Multi-modal Intervention Care on Cachexia in Patients With Advanced Cancer Compared to Conventional Management (MIRACLE)
Background Cancer Cachexia (CC) is a multi-factorial process characterized by progressive weight loss, muscle mass and fat tissue wasting, and adversely affecting their quality of life and survival in patients with advanced stage…
- Conditions
- Gastric Cancer, Colorectal Cancer, Pancreatic Cancer, Biliary Tract Cancer
- Trial name
- MIRACLE (NCT04907864)
- Testing
- Multi-modal intervention
- Where
- South Korea
- Volunteers
- 112 people
- Sponsor
- Kil Yeon Lee
Cholangiopancreatography, Endoscopic Retrograde, Common Bile Duct Lithiasis
Quality Assessment in Endoscopic Retrograde Cholangiopancreatography(ERCP)
The investigators will prospectively collect patient and procedure-related data in an observational study in order to detect patient and procedure-related risk factors for poor outcome (i.e.
- Conditions
- Cholangiopancreatography, Endoscopic Retrograde, Common Bile Duct Lithiasis, Biliary Strictures, Bile Duct and Pancreatic Tumors
- Trial name
- QUASIE2 (NCT02698137)
- Where
- 3 sites in Croatia, Italy and 1 more
- Volunteers
- 1,843 people
- Sponsor
- Clinical Hospital Colentina
Pancreatic Neoplasms, Bile Duct Carcinoma
Whipple Procedure: Standard of Care vs. Thunderbeat
The Whipple procedure is the standard method for therapy for cancerous tumors, inflammation, and stenosis (narrowing) near the head of the pancreas.
- Trial name
- NCT02204124
- Testing
- Thunderbeat, Standard of care scissors, ligatures, clips, and sutures
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Washington University School of Medicine
Radiation Exposure
Patients Radiation Exposure in Percutaneous Transhepatic Biliary Drainage (PTBD) Procedures
Percutaneous transhepatic biliary drainage (PTBD) procedures are associated with an elevated radiation exposure for the patient.
- Trial name
- NCT03538782
- Testing
- Percutaneous biliary drainage
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- Theresienkrankenhaus und St. Hedwig-Klinik GmbH
Acute Cholecystitis, Empyema
Drainage is Not Necessary Procedure After Laparoscopic Cholecystectomy Due to Severe Acute Cholecystitis
Laparoscopic cholecystectomy (LC) is the current preferred method of cholecystectomy. The role of routine drainage after LC to decrease postoperative morbidity is still an issue of considerable debate.
- Trial name
- NCT01625247
- Testing
- Surgical drainage
- Where
- South Korea
- Volunteers
- 162 people
- Sponsor
- Yonsei University
ERCP
Early Intervention of High Tension in the Pancreatic Duct on the Outcome of Severe Biliary Pancreatitis
The investigators hypothesized that naso-pancreatic duct suction could benefit for patients with severe biliary pancreatitis undergoing ERCP. So, the investigators designed this experiment to verify it.
- Trial name
- NCT04255095
- Testing
- experiment, control
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Renmin Hospital of Wuhan University
Primary Biliary Cholangitis
A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment
This study will collect information from participants with Primary Biliary Cholangitis (PBC) as they use the drug elafibranor in real world setting.
- Trial name
- ELFINITY (NCT06447168)
- Where
- 72 sites in United States, Australia and 9 more
- Volunteers
- 424 people
- Sponsor
- Ipsen
Gallstones
Safety Study of Keyhole Gallbladder Surgery With Removal of Gallbladder Via the Stomach Rather Than Through the Skin
The benefits of laparoscopic ("minimally invasive" or "keyhole") surgery for gallbladder removal (cholecystectomy) over open surgical procedures in terms of significant reductions in pain, scarring and recovery time are well…
- Trial name
- NCT01010685
- Testing
- Recovery of gallbladder via gastrotomy instead of via the skin
- Where
- United Kingdom
- Sponsor
- Colchester Hospital University NHS Foundation Trust
Bariatric Surgery Candidate, Cholelithiases
Safety and Feasibility of the Use of the Dual Robotic Arm Accessory With the Levita Magnetic Surgical System in Laparoscopic Procedures
The purpose of this study is to evaluate the safety and feasibility of the Levita Dual Robotic Arm Accessory (DRAA) used with the Levita Magnetic Surgical System (MSS)
- Conditions
- Bariatric Surgery Candidate, Cholelithiases, Other Disease
- Trial name
- MARS GI (NCT05695989)
- Testing
- Dual Robotic Arm Accessory (DRAA)
- Where
- 3 sites in Chile
- Volunteers
- 22 people
- Sponsor
- Levita Magnetics
Acute Cholecystitis
Conservative Versus Proactive Management of Acute Cholecystitis After EUS-guided Transmural Gallbladder Drainage: FUGITIVE Trial (FUGITIVE)
Patients with gallbladder inflammation (acute cholecystitis) who cannot undergo surgery due to their fragility and surgical risk require a gallbladder drainage.
- Trial name
- FUGITIVE (NCT06967597)
- Testing
- Cholecystoscopy and gallbladder cleaning
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- Hospital General Universitario de Alicante
Pancreatic Cancer, Bile Duct Cancer
A Registry of Patients Undergoing Cellvizio Endomicroscopy and Endoscopic Retrograde Cholangiopancreatography(ERCP) Imaging Procedures for Diagnosing Pancreatic and Bile Duct Cancers
This registry will collect data from patients routinely undergoing an ERCP and Cellvizio endomicroscopy procedure (and optionally an additional cholangiopancreatoscopy procedure) due to suspected pancreatic or bile duct cancer.
- Trial name
- NCT00779688
- Testing
- Probe-based confocal laser endomicroscopy
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 130 people
- Sponsor
- Mauna Kea Technologies
Short Message Service, Adherence
Effect of Short Message Service Intervention on Stent Removal/Exchange Adherence in Patients With Benign Pancreaticobiliary Diseases
Endoscopic implantation of plastic or covered metal stents is widely used in a variety of benign pancreaticobiliary diseases, including duct stricture, large or difficult stones, bile or pancreatic juice leak, etc.
- Conditions
- Short Message Service, Adherence, Stent Exchange, ERCP
- Trial name
- NCT02041390
- Testing
- SMS reminder, Conventional reminder
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Air Force Military Medical University, China
Interventional Radiology
The Impact of Puncture Angle on Total Fluoroscopy Time Reduction During Percutaneous Biliary Drainage
The purpose of this study is to retrospectively assess the importance of initial bile duct puncture angle on total fluoroscopy time and overall efficacy during ultrasound and fluoroscopy guided percutaneous transhepatic biliary…
- Trial name
- NCT04653987
- Testing
- Percutaneous biliary drainage
- Volunteers
- 130 people
- Sponsor
- Institut za Rehabilitaciju Sokobanjska Beograd
Cholecystitis
US-guided Trocar Versus Seldiger Technique for Percutaneous Cholecystostomy
A single-center randomized comparison of bedside ultrasound (US)-guided trocar technique versus the US-guided Seldinger technique for percutaneous cholecystostomy
- Trial name
- TROSELCII (NCT04602156)
- Testing
- Trocar percutaneous cholecystostomy, Seldinger percutaneous cholecystostomy
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Attikon Hospital