Clinical trials: Binge Eating Disorder
Alcohol Use Disorder, HIV/AIDS
Understanding and Intervening With Heavy Drinking Among Patients With HIV and HCV
Among patients with HIV, especially those also infected with HCV, heavy drinking is associated with significant risks to health.
- Conditions
- Alcohol Use Disorder, HIV/AIDS, Hepatitis C, Binge Drinking
- Trial name
- NCT03652675
- Testing
- Intervention: (Clinician's Guide + HealthCall for HIV/HCV)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- New York State Psychiatric Institute
Binge Eating, Eating Disorders in Adolescence
Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating
This study will develop and test a cognitive-behavioral intervention for adolescents with binge/loss-of-control eating.
- Conditions
- Binge Eating, Eating Disorders in Adolescence, Overweight and Obesity
- Trial name
- NCT04088097
- Testing
- Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating, Control Condition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Binge Eating Disorder
Follow-Up Extension to the Family Study of Binge Eating Disorder
This study involves a 2.5 and 5 year follow-up interview for individuals who participated in the initial family study of binge eating disorder.
- Trial name
- NCT00777634
- Testing
- No intervention.
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Anorexia Nervosa/Bulimia, Anorexia in Adolescence
Oral Naltrexone In Pediatric Eating Disorders
The objective of this study is to evaluate the effectiveness of oral naltrexone tablets in pediatric and adolescent eating disorders, in particular anorexia nervosa and bulimia nervosa, as compared to placebo.
- Conditions
- Anorexia Nervosa/Bulimia, Anorexia in Adolescence, Anorexia Nervosa, Atypical, Anorexia Nervosa, Binge Eating/Purging Type
- Trial name
- ONPED (NCT05073679)
- Testing
- Naltrexone Hydrochloride, Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Rosemary Claire Roden
Binge Eating Disorder
Open Label Extension in Adults With Binge Eating Disorder (BED)
To evaluate the safety and tolerability of SPD489 administered as a daily morning dose (50 or 70mg) in the treatment of moderate to severe binge eating disorder (BED) in adults
- Trial name
- NCT01657019
- Testing
- Lisdexamfetamine dimesylate
- Where
- 89 sites in United States, Germany and 1 more
- Volunteers
- 604 people
- Sponsor
- Shire
Obesity, Binge Eating
Testing Intervention Strategies for Addressing Obesity and Binge Eating
The purpose of this study is to conduct a randomized pilot trial of a mobile intervention that targets obesity and binge eating.
- Trial name
- NCT04771455
- Testing
- Behavioral weight loss, Intervention component: Decrease overvaluation of weight and shape, Intervention component: Decrease unhealthy weight control practices
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Northwestern University
Binge-Eating Disorder
Uniting Couples in the Treatment of Binge-Eating Disorder
The purpose of this study is to test the feasibility, acceptability, and preliminary effectiveness of a novel couple-based intervention for binge-eating disorder (BED) relative to an established evidence-based individual…
- Trial name
- UNITE (NCT03784820)
- Testing
- UNITE, CBT-E
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of North Carolina, Chapel Hill
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Binge Eating Disorder
SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
The primary objective of the study is to demonstrate the efficacy of SPD489 compared with placebo in adults (18 55 years of age inclusive) with moderate to severe Binge Eating Disorder at Visit 8 (Weeks 11 and 12) as measured by…
- Trial name
- NCT01718483
- Testing
- SPD489 (Lisdexamfetamine dimesylate)
- Where
- 50 sites in United States, Germany and 2 more
- Volunteers
- 383 people
- Sponsor
- Shire
Bulimia Nervosa, Binge Eating
Binge Eating & Birth Control
This pilot study examines the effect of stabilizing ovarian hormones on eating behaviors and brain activation in women with binge eating (n=15) using functional magnetic resonance imaging (fMRI) and behavioral tests.
- Conditions
- Bulimia Nervosa, Binge Eating, Eating Disorders, Binge-Eating Disorder
- Trial name
- NCT04278755
- Testing
- Drospirenone-Ethinyl Estradiol Oral Tablet
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of North Carolina, Chapel Hill
Binge Eating Disorder
Evaluate the Maintenance of Efficacy of SPD489 in Adults Aged 18-55 Years With Moderate to Severe Binge Eating Disorder
To evaluate maintenance of efficacy based on time to relapse between SPD489 (50 or 70mg) and placebo, as measured by the number of binge days (defined as days during which at least 1 binge episode occurs) per week as assessed by…
- Trial name
- NCT02009163
- Testing
- Lisdexamfetamine dimesylate
- Where
- 53 sites in United States, Canada and 3 more
- Volunteers
- 418 people
- Sponsor
- Shire
Binge-Eating Disorder, Circadian Rhythm Disorders
The Role of the Circadian System in Binge Eating Disorder
Binge eating disorder (BED) shows prominent circadian features that suggest a delay in circadian phase, and preliminary evidence shows binge eating may be responsive to chronobiological interventions, implicating a circadian…
- Trial name
- CHRONO-BE (NCT04724668)
- Testing
- Melatonin (3hrs before DLMO), Morning light version 1, Morning light version 2
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Binge Eating Disorder
Dasotraline Binge Eating Disorder Extension Study
Binge Eating Disorder Extension Study.
- Trial name
- NCT02684279
- Testing
- Dasotraline
- Where
- 57 sites in United States
- Volunteers
- 533 people
- Sponsor
- Sumitomo Pharma America, Inc.
Binge-Eating Disorder, Obesity
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy
This study will test the effectiveness and relative efficacy of naltrexone/bupropion medication as a maintenance therapy for the treatment of binge eating disorder (BED) in patients with obesity.
- Trial name
- NCT03047005
- Testing
- NB medication (Naltrexone Bupropion combination)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Yale University
Bulimia Nervosa
Neurobiology of Bulimia Nervosa
This pilot study experimentally manipulates ovarian hormones to examine the direct impact of estrogen (E2) and progesterone (P4) on binge eating symptom burden and the behavioral reward response in women with bulimia nervosa…
- Trial name
- NCT04225221
- Testing
- Estradiol, Micronized progesterone, Leuprolide Acetate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of North Carolina, Chapel Hill
Bulimia Nervosa, Eating Disorders
Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
This study will determine the effectiveness of the antibiotic erythromycin in enhancing gastrointestinal function and decreasing the frequency of binge eating in people with bulimia nervosa.
- Trial name
- NCT00304187
- Testing
- Erythromycin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Binge Eating Disorder, Overweight and Obesity
Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
The purpose of this research is to conduct a randomized controlled trial (RCT) assessing the impact of CBT on neural responses to binge eating stimuli.
- Trial name
- NCT03604172
- Testing
- Cognitive behavioral therapy, Waitlist
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Binge Eating Disorder
A Study to Evaluate a Drug (Dasotraline) on the Safety, Effectiveness and How Well the Body Tolerates it, in Adults With Moderate to Severe Binge Eating Disorder
A study to evaluate a drug (dasotraline) on the safety, effectiveness and how well the body tolerates it, in adults with moderate to severe binge eating disorder
- Trial name
- NCT03107026
- Testing
- dasotraline 4mg, dasotraline 6mg
- Where
- 50 sites in United States
- Volunteers
- 491 people
- Sponsor
- Sumitomo Pharma America, Inc.
Bulimia Nervosa, Bulimia; Atypical
Reward Re-Training: A New Treatment to Address Reward Imbalance During the COVID-19 Pandemic
In the current study, the investigators will revise our existing 10-session group RRT treatment manual to specifically address the challenges in building social support and enhancing both momentary and sustained reward during the…
- Conditions
- Bulimia Nervosa, Bulimia; Atypical, Binge Eating, Binge-Eating Disorder
- Trial name
- NCT04661410
- Testing
- Reward Re-Training, Supportive Therapy
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Drexel University
Obesity, Binge Eating
Treatment of Binge Eating in Obese Patients in Primary Care
This study will test the effectiveness of two empirically-supported but distinct treatments for recurrent binge eating in obese patients: 1) Cognitive Behavior Therapy, using a pure self-help approach and 2) sibutramine, an…
- Trial name
- NCT00537810
- Testing
- Sibutramine, Self-help CBT + Sibutramine
- Where
- 3 sites in United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Yale University