Clinical trials: Biochemical Marker
Breast Cancer
Effect of a Fruit- and Chaya-Based Diet on Genomic Instability and Biochemical Markers in Women With Breast Cancer Receiving Chemotherapy
This exploratory, non-randomized clinical study aims to evaluate the potential impact of a diet enriched with fruits and chaya (Cnidoscolus aconitifolius) infusion on genomic instability and selected biochemical parameters in…
- Trial name
- NCT07015294
- Testing
- Fruits and chaya infusion, Conventional diet
- Where
- Mexico
- Volunteers
- 13 people
- Sponsor
- Anahuac Mayab University
Cardiovascular Diseases, Heart Failure
Novel Echocardiographic Biomarkers Assessing the Myocardial Work in Heart Failure
This study seeks to investigate the clinical value of novel echocardiographic indices, including myocardial work parameters, during the acute phase of heart failure hospitalization.
- Conditions
- Cardiovascular Diseases, Heart Failure, Valvular Heart Disease, Biochemical Dysfunction
- Trial name
- Beyond-MyoHF (NCT05573997)
- Testing
- Investigation of clinical profile, laboratory and novel echocardiographic imaging biomarkers
- Where
- Greece
- Volunteers
- 300 people
- Sponsor
- Aristotle University Of Thessaloniki
Ischaemic Heart Disease, Aortic Stenosis
Remifentanil/Sufentanil for CABG+/-AVR Evaluated by Recovery, Cognitive Function, Haemodynamics and Biochemical Markers.
To evaluate the effect on cognitive function, recovery, cardioprotection and haemodynamics of standard Remifentanil anaesthesia to standard Sufentanil anaesthesia in patients undergoing coronary artery bypass with or without…
- Trial name
- PRECON2 (NCT02053818)
- Testing
- Remifentanil, Sufentanil
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Detection of Preeclampsia Complications
Pre-eclampsia and Biochemical Markers
In view of both endothelial injury in pre-eclampsia, high blood pressure and kidney impairment characteristics, a recent study demonstrated that the serum levels of NGAL increased at the end of the second trimester in women who…
- Trial name
- PET (NCT02665897)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Healthy Volunteers
Study of Biochemical Markers to Determine the Acetylsalicylic Acid Chemopreventive Effect Through Antiplatelet Action
This study in healthy volunteers is the first step in developing a collaborative research program, which seeks to test the hypothesis that chemopreventive effect of acetylsalicylic acid (ASA) on colon cancer is due predominantly…
- Trial name
- NCT02060396
- Testing
- Acetylsalicylic acid
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aragon Institute of Health Sciences
Cardiotoxicity, Aluminum Phosphid Poisoning
Cardiotoxicity of Aluminum Phosphide Poisoning; Tropinin and CKmb as Early Biomarkers
Aluminum phosphide (AlP) or rice tablet is a cheap pesticide. When it comes in contact with acid (gastric acid) or moisture, it releases phosphine (PH3) gas.
- Trial name
- NCT04191265
- Testing
- serum tropinin, serum CKmb
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypertensive Heart Disease Without (Congestive) Heart Failure
The Influence of Beetroot Powder at a Dose of 20 g on Blood Pressure, Microcirculation, and Biochemical Markers in Men With Arterial Hypertension.SVEKLA2025.
Objective: to evaluate the effectiveness of using a food product, dry finely dispersed beetroot powder in a dose of 20 g, containing 800 mg of nitrate (NO3-), in relation to the regulation of blood pressure in men with…
- Trial name
- NCT07270718
- Testing
- Plus SVEKLA
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Saturation Exposure, Decompression Injury
Inflammatory and Cerebrospinal Biochemical Markers in Blood During Prolonged Hyperbaric Exposure
Research hypothesis Prolonged hyperbaric exposure will affect the central nervous system Prolonged hyperbaric exposure will induce inflammatory changes Prolonged hyperbaric exposure will affect fluid regulation in the body…
- Trial name
- Mättnad2017 (NCT03192930)
- Testing
- Hyperbaric exposure
- Where
- Sweden
- Volunteers
- 26 people
- Sponsor
- Sahlgrenska University Hospital
Breast Cancer
6xFU/Epirubicin/Cyclophosphamide (FEC) Compared to 3xFEC-3xDocetaxel in High-risk Node-negative Breast Cancer Patients
In low-risk node-negative breast cancer patients adjuvant chemotherapy should be spared. The identification of this subgroup can be based either on clinical and pathological or on tumour-biological criteria.
- Trial name
- NNBC3-Europe (NCT01222052)
- Testing
- 5-Fluorouracil, Epirubicin, Cyclophosphamide, Docetaxel
- Where
- Germany
- Volunteers
- 4,150 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Fatty Liver, Diabetes Mellitus, Type 2
Effects of Ginger on Nonalcoholic Fatty Liver Disease in T2DM
The investigators want to evaluate the effects and safety of ginger in treatment of nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- GinLivDM (NCT02289235)
- Testing
- Ginger
- Where
- Iran
- Volunteers
- 76 people
- Sponsor
- Shiraz University of Medical Sciences
Osteoporosis
A Study to Test Once-Weekly Doses of Odanacatib (MK0822) on Healthy Adult Females (0822-005)(COMPLETED)
This study will assess the safety, tolerability, PK, and PD of a once weekly dose of MK0822 in healthy postmenopausal women.
- Trial name
- NCT00770159
- Testing
- odanacatib
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Oxidative Stress, Inflammation
Effect of Alpha-lipoic Acid on Biochemical Markers and Important Outcomes in Patients Admitted to Intensive Care Units
Increasing Reactive oxygen and nitrogen production occurred simultaneously with decreasing serum and intracellular level of antioxidants and enzymes in critical ill patients, which result in increasing ventilator dependency and…
- Conditions
- Oxidative Stress, Inflammation, Malnutrition
- Trial name
- NCT01888861
- Testing
- alpha-lipoic acid
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- najmeh hejazi
Beta-Thalassemia
Iron Status in BTM With Blood Transfusion
To assess the possible role of iron overload as a cause of liver dysfunction in thalassemic childrens receiving multiple blood transfusion and its correlation with serum aminotransferases.
- Trial name
- NCT04947540
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Prediabetes, Hyperglycemia
Personality Traits and Biochemical Risk Phenotypes
This prospective observational study investigates the association between personality traits and routine laboratory abnormalities in adults undergoing routine health assessment.
- Conditions
- Prediabetes, Hyperglycemia, Metabolic Syndrome
- Trial name
- PHEBiP (NCT07653048)
- Where
- Romania
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Medical Center TOPMED
Behcet Disease and Vascular Involvement
Clinical, Biochemical and Epigenetic Profile of Pediatric Behçet Disease
Behçet disease (BD) is a chronic multisystem inflammatory disorder with a relapsing-remitting course. Pediatric-onset BD is rare and characterized by marked clinical heterogeneity, frequent incomplete presentation at disease…
- Trial name
- PED-BD (NCT07375940)
- Testing
- Biomarker analysis of blood samples
- Where
- 2 sites in Italy, United Kingdom
- Volunteers
- 90 people
- Sponsor
- Meyer Children's Hospital IRCCS
Primary Graft Dysfunction
Quantifying Physical and Biochemical Factors That Contribute to Primary Graft Dysfunction After Lung Transplantation
Primary graft dysfunction (PGD or lung reperfusion edema) complicates 10 to 20% of lung transplantations and leads to severe early and late postoperative complications.
- Trial name
- NCT01151826
- Where
- 4 sites in France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Strasbourg, France
Osteoporosis, Nutrition
Validation of a Revised Food Frequency Questionnaire
The purpose of this study is to validate a revised food frequency questionnaire that is designed to capture vitamin D, calcium and protein intake in a population of elderly men and women with fragility fractures.
- Trial name
- FFQ (NCT02693184)
- Testing
- Full length Block 2014 Food Frequency Questionnaire, Revised Calcium, Vitamin D and Protein Screener
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Nebraska
Exercise
Effects of Elastic Resistance Training on Performance and Biochemical Parameters
The aim of this study was to investigate the acute and chronic effect of elastic resistance exercise in elderly women living in a nursing home. The primary outcome was the functional performance and hand grip strength.
- Trial name
- NCT03282175
- Testing
- Exercise, Training, Control group
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Pseudoexfoliation Syndrome, Carpal Tunnel Syndrome (CTS)
Pseudoexfoliation and Carpal Tunnel Study
This prospective, single-center case-control study aimed to investigate the association between pseudoexfoliation syndrome (PES) and carpal tunnel syndrome (CTS) using biochemical markers.
- Trial name
- NCT06946030
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Prostate Cancer
Genetic Testing in Predicting Biomarkers of Recurrence in Patients With Prostate Cancer Undergoing Surgery
This trial studies the side effects and best way to perform genetic testing in predicting biomarkers of recurrence in patients with prostate cancer undergoing surgery.
- Trial name
- NCT00977457
- Testing
- DNA analysis, DNA methylation analysis, RNA analysis
- Where
- United States
- Volunteers
- 1,045 people
- Sponsor
- City of Hope Medical Center