Clinical trials: Biochemical Marker
Hypertension, Hypercholesterolemia
Efficacy and Safety of Valsartan and the Combination of Valsartan and Simvastatin
This study will assess and compare the efficacy and safety of valsartan and the combination of valsartan and simvastatin in patients with high blood pressure and high cholesterol.
- Conditions
- Hypertension, Hypercholesterolemia, Dyslipidemia
- Trial name
- NCT00385931
- Testing
- Valsartan and simvastatin
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Novartis
Anemia, Iron Deficiency
Treatment of Iron Deficiency Anaemia in Pregnancy Study
The burden of anaemia remains unacceptably high during pregnancy. Over a third of women are anaemic by their third trimester of pregnancy. The most common cause is iron deficiency.
- Trial name
- TIAP (NCT03725150)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Diabetic Foot Ulcer, Wound Healing
Systemic Biochemical Signature and Functional Quality Index of Calcaneal Bone Marrow Aspirate in Adults Undergoing Foot or Ankle Surgery
This observational prospective cohort study will evaluate whether routine blood tests are associated with the functional quality of calcaneal bone marrow aspirate mesenchymal stem cells in adults undergoing clinically indicated…
- Conditions
- Diabetic Foot Ulcer, Wound Healing, Foot Ulcer Due to Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2
- Trial name
- IQF-BMA (NCT07802106)
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Sao Francisco
Low Risk for Cardiovascular Disease
Health Benefits of Functional Meat (With n-3 Fatty Acids and Rosemary Extract) on Low Risk for Cardiovascular Disease People
Volunteers were randomly assigned by gender to follow of two 12 weeks experimental periods: intervention (I) and control (C) in different order (I/C or C/I).
- Trial name
- NCT01999088
- Testing
- Functional Meet, Control Meat
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Obesity and Psoriasis
The Effect of Ketogenic Diet Versus Mediterranean Diet in Patients With Obesity and Psoriatic Arthritis
The aim of our study is to compare the effectiveness of Mediterranean diet (MD) with the isocaloric Ketogenic diet (KD) on clinical and biochemical markers of inflammation in patients with obesity, psoriasis (PSO) and psoriatic…
- Trial name
- NCT06164860
- Testing
- Meditteranean Diet, Ketogenic Diet
- Where
- Greece
- Volunteers
- 26 people
- Sponsor
- Attikon Hospital
Paget's Disease of Bone
18F-Fluoride Positron Emission Tomography (PET) in Paget's Disease of Bone
18 F-fluoride Positron emission tomography (PET) is able to demonstrate and quantify the metabolic activity locally in the skeleton (1).
- Trial name
- NCT00306046
- Testing
- Bisphosphonate treatment
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Catholique de Louvain
Chronic Rhinosinusitis
Chronic Rhinosinusitis: Biochemical Markers and Biofilm
The investigators will conduct a descriptive, prospective, three-armed study concerning the pathophysiology of chronic rhinosinusitis.
- Trial name
- NCT01084811
- Testing
- biopsy
- Where
- Norway
- Volunteers
- 230 people
- Sponsor
- University Hospital, Akershus
Prostate Cancer
Effects of EPA in Men With Biochemical Recurrence or Progression of Prostate Cancer.
Prostate cancer biochemical recurrence (BCR) occurs in 20-50% of patients following radical prostatectomy or radiotherapy. Due to significant risk of side effects and uncertainty about the benefits, physicians and patients are…
- Trial name
- RCT-EPAII-BCR (NCT03753334)
- Testing
- MAG-EPA
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- CHU de Quebec-Universite Laval
Parkinson Disease
Parkinson's Disease Biomarkers in Nerve Cells in the Gut
Parkinson's disease affects all the nerve cells in the body, including the ones in the gut. The gut contains its own nervous system, the enteric nervous system, and can be thought of as a "second brain".
- Trial name
- PD-ENS (NCT05347407)
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Peri-implantitis, Guided Bone Regeneration
Collagen Membrane and Allograft in Peri-Implantitis Surgery
Peri-implantitis is an inflammatory condition characterized by inflammation of the peri-implant tissues and progressive loss of supporting bone around dental implants.
- Conditions
- Peri-implantitis, Guided Bone Regeneration, Biochemical Markers
- Trial name
- CMAPI (NCT07478978)
- Testing
- Collagen Membrane + Allograft, Allograft
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ondokuz Mayıs University
Soccer, Fatigue
Comparison Between Photobiomodulation Therapy (PBMT) and a Cold-Water Immersion (CWI) in Recovery Soccer Player: Analysis of Biochemical Markers of Recovery and Muscular Oxidative Stress.
Competitive soccer engages many of the body's systems to a major extent. The musculoskeletal, nervous, immune and metabolic systems are stressed to a point where recovery strategies post-exercise become influential in preparing…
- Conditions
- Soccer, Fatigue, Oxidative Stress, Recovery
- Trial name
- NCT03593733
- Testing
- Photobiomodulation Therapy, Cold Water Immersion
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- LUCIANA MARIA MALOSA SAMPAIO
Abdominal Aortic Aneurysm
Biomarkers of Aneurysm Wall Strength
The purpose of this study is to identify possible in vivo biochemical and biological markers related to aortic wall strength.
- Trial name
- NCT00740740
- Where
- 2 sites in Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
Multiple Sclerosis
Evaluation of Clinical, Morphologic and Biochemical Markers in Multiple Sclerosis
By combining clinical, morphological and biochemical markers a better understanding of the formation and progression of multiple sclerosis (MS) should be obtained
- Trial name
- NCT04892134
- Testing
- blood sample
- Where
- Austria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
PREGNANCY
Induction Versus Expectant Management With Abnormal Maternal Biochemical Markers
Induction of labor at term versus expectant management among women with abnormal maternal biochemical markers. A randomized controlled trial
- Trial name
- NCT02754635
- Testing
- Induction of labour, Expectant management
- Where
- Israel
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Congenital Heart Disease, Cardiopulmonary Bypass
Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass
The current proposal tests the central hypothesis that acetaminophen will attenuate the oxidative stress response associated with cardiopulmonary bypass (CPB)-induced hemolysis in children undergoing cardiac surgery.
- Trial name
- NCT01228305
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University Medical Center
Rosacea
Effects of Aminocaproic Acid (ACA) on Rosacea-specific Inflammation
The purpose of this study is to determine the effect of topical aminocaproic acid on the immune system by assessing the levels of antimicrobial peptides in the skin of patients with rosacea.
- Trial name
- ACA (NCT01398280)
- Testing
- Topical aminocaproic acid (ACA) mixed with Vanicream, Vehicle cream
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Diego
Obese Adolescents, Overweight
Effect of Acute Exercise on Biochemical Parameters in Normal-Weight and Overweight/Obese Adolescent.
The goal of this interventional clinical trial is to compare the acute physiological and biochemical responses to maximal physical exercise (Spartacus test).
- Trial name
- NCT07103889
- Testing
- Spartacus Test
- Where
- Tunisia
- Volunteers
- 35 people
- Sponsor
- High Institute of Sports and Physical Education of Kef
Heart Failure, Heart Dilation
The Use of Blood Biochemical Markers for Diagnostics of Heart Muscle Diseases
The aim of the study is to determine the analytical characteristics of the microRNA enzymatic immunoassay (miREIA) method and to determine various relations among miRNA biomarkers and heart failure (HF) with reduced ejection…
- Conditions
- Heart Failure, Heart Dilation, Left Ventricular Hypertrophy
- Trial name
- NCT05726695
- Testing
- microRNA test, Heart ultrasound examination
- Where
- Czechia
- Volunteers
- 200 people
- Sponsor
- University Hospital Ostrava
Heart Failure
A Pilot Study Comparing the Programmed Delay Between the Atrial and Ventricle Interval
The idea of this study is to compare different ways of setting up a pacemaker, using blood tests to give us information about how well it's working.
- Trial name
- BRAVO-CRT (NCT00794183)
- Testing
- CRT device settings
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Minnesota
Atrial Fibrillation
Biochemical Marker to Predict the Recurrence of Atrial Fibrillation After Surgical Maze Procedure
The role of plasma NT-proBNP, hsCRP, TIMP-1(Tissue inhibitors of MetalloProteinase-1),TGF-b, MMP-3(Matrix MetalloProteinase-3), and pro-MMP-1 in predicting the recurrence of AF after surgical Maze procedure.
- Trial name
- NCT00542659
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Samsung Medical Center