Clinical trials: Biologic Implant
Cervicovaginitis, Endometriosis
Establishment of the Human Intestinal and Salivary Microbiota Biobank - Gynecological Diseases
This is a prospective, clinical, monocentric study aimed to collect biological samples and study microbiota from subjects suffering from subjects with recurrent cervicovaginitis, subjects with endometriosis, subjects with…
- Conditions
- Cervicovaginitis, Endometriosis, Repeated Implantation Failure
- Trial name
- BIOMIS-DIMO (NCT04698109)
- Testing
- Biological sample collection, Questionnaire, Medical examination
- Where
- Italy
- Volunteers
- 103 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Breast Cancer
Breast Reconstruction With Acellular Dermal Matrix in the Setting of Breast Cancer Treatment
To evaluate breast reconstruction with implants using biological mesh (Strattice™) in the setting of breast cancer treatment.
- Trial name
- NCT02061527
- Testing
- Reconstruction with ADM., Skin or nipple sparing mastectomy, Reconstruction with implant
- Where
- 5 sites in Sweden, United Kingdom
- Volunteers
- 135 people
- Sponsor
- Karolinska University Hospital
Edentulism, Tooth Loss
Mandibular Biological Drilling at Different Speeds for Dental Implant Placement
This randomized controlled clinical trial aims to evaluate the effect of different biological drilling speeds (50, 150, and 300 rpm) during implant osteotomy preparation in the mandible on marginal bone level changes and implant…
- Trial name
- NCT07474454
- Testing
- biological drilling at 50 RPM, biological drilling at 150 RPM, biological drilling at 300 RPM
- Volunteers
- 39 people
- Sponsor
- Cairo University
Knee Osteoarthritis, Chronic Inflammatory Rheumatism
IDENTIFICATION OF BIOMARKERS ASSOCIATED WITH THE SEVERITY AND RADIO-CLINICAL PROGRESSION OF KNEE OSTEOARTHRITIS
Knee osteoarthritis (OA) is an heterogeneous disease, both symptomatically and structurally, with very different evolving profiles.
- Trial name
- BIOGO (NCT06600958)
- Testing
- SA brief descriptive name used to refer to the intervention(s) studied
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Cysts, Bone Atrophy
Gene-activated Bone Substitute for Maxillofacial Bone Regeneration
The purpose of this study is to evaluate the safety and efficacy of the gene-activated bone substitute consisting of octacalcium phosphate and plasmid DNA encoding vascular endothelial growth factor (VEGF) for maxillofacial bone…
- Conditions
- Bone Cysts, Bone Atrophy, Bone Deformity, Bone Fracture
- Trial name
- NCT03076138
- Testing
- Gene-activated matrix (OCP + plasmid DNA with VEGF gene)
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Histograft Co., Ltd.
Incisional Hernia
PROPHYlactic Implantation of BIOlogic Mesh in Peritonitis (PROPHYBIOM)
To evaluate the efficacy of the use of swine dermal collagen prosthesis implanted preperitoneally as a prophylactic procedure against incisional hernia in patients operated in urgency/emergency setting in contaminated/infected…
- Trial name
- PROPHYBIOM (NCT02277262)
- Testing
- Biological swine dermis not cross-linked prosthesis positioning in incisional hernia prevention, Direct suture of the anterior abdominal wall fascia
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Aortic Valve Disease
Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2020 in under…
- Trial name
- NCT05627973
- Testing
- Aortic Valve Replacement
- Volunteers
- 991 people
- Sponsor
- Medical University of Vienna
Dental Implant, Osseointegration
Assessment of Early Healing Period of Dental Implants
This prospective cohort study aimed to evaluate, clinically, radiographically, and digitally, the volumetric changes occurring during the early healing period after implant treatment in patients with tooth loss in the posterior…
- Conditions
- Dental Implant, Osseointegration, Biological Width
- Trial name
- NCT06554444
- Testing
- Dental Implant Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Implant Stability, Low Speed Drilling
Clinical Evaluation of Biological Drilling Osteotomy Protocol Versus Conventional Drilling Osteotomy Protocol
This study aims to evaluate the effect of biological drilling osteotomy protocol compared to conventional osteotomy protocol in delayed implant placement in the posterior mandible regarding implant stability Type of study design…
- Trial name
- NCT06992557
- Testing
- Biological drilling osteotomy protocol, Conventional drilling osteotomy protocol
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Women Wanting Contraceptive Implant for Pregnancy Prevention
A Trial on the Effect of Sino-implant (II) Use on Condom Use Among Women in Kingston, Jamaica
This unblinded, randomized controlled trial (RCT) among women to determine: 1)if unprotected sex as measured prostate-specific antigen (PSA) will be more among women who receive a contraceptive implant immediately at baseline…
- Trial name
- SIS (NCT01684358)
- Testing
- Sino-implant (II)
- Where
- Jamaica
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Thrombosis
Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis Surgery
Knee prothesis surgery is responsible of a risk of thrombosis and hemorrhage. To prevent thrombosis, patients have systematic anticoagulation after surgery which are responsible of hemorrhage.
- Trial name
- NCT00983112
- Testing
- Human Fibrinogen and human thrombin (Evicel), Sodium Chlorure (Physiological saline)
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Clinique Mutualiste Chirurgicale de la Loire
Biological Markers; Dental Implants; Cytokines; Triclosan; Toothpastes; Peri-Implantitis; Microbiology
Impact of a Triclosan-containing Toothpaste During the Progression of Experimental Peri-implant Mucositis
The aim of this study was to evaluate the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) and in the clinical parameters during the…
- Trial name
- NCT03145610
- Testing
- triclosan/copolymer/fluoride toothpaste
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Paulista University
Infertility
Study to Estimate Seedchrony's Predictive Capacity in the Success of Embryo Implantation.
In Vitro Fertilization (IVF) success is below 40%, with Embryo Transfer the leading cause of IVF failure. This clinical investigation aims to evaluate if the levels of an intrauterine biomarker dissolved in the uterine fluid…
- Trial name
- Seedchrony02 (NCT06259084)
- Testing
- Seedchrony
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Manina Medtech