Clinical trials: Biopsy Wound
Wound Heal, Postoperative Pain
Assessing the Efficacy of a Hydrogen Peroxide Gel for Oral Wound Healing and Oral Hygiene
This study aims to assess the effectiveness and safety of a hydrogen carbamide/peroxide gel, called UNISEPT® ORAL GEL, in promoting oral wound healing, alleviating postoperative symptoms, and enhancing oral hygiene.
- Conditions
- Wound Heal, Postoperative Pain, Biopsy Wound, Wound; Mouth
- Trial name
- NCT06370260
- Testing
- Hydrogen Carbamide/Peroxide Gel
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- National and Kapodistrian University of Athens
Implantation Failure, Infertility
Endometrial Biopsy Prior to IVF in Those Patients With Prior Implantation Failure
This proposed research is a single center, prospective, single-blinded, randomized controlled trial, designed to evaluate IVF pregnancy outcomes following endometrial injury in 254 patients with implantation failure.
- Trial name
- EMBX/IVF (NCT01800513)
- Testing
- Endometrial Biopsy
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- Shady Grove Fertility Reproductive Science Center
Hepatocellular Carcinoma, Liver Transplant; Complications
Impact of Graft Reconditioning With Hypothermic Machine Perfusion on HCC Recurrence After Liver Transplantation
The use of devices for liver grafts perfusion before transplantation, either hypothermic (HOPE) or normothermic (NMP), is rapidly spreading thanks to the promising results obtained so far in terms of graft survival and…
- Trial name
- NCT06236568
- Testing
- D-HOPE machine perfusion, Liver transplantation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Quality of Life, Biopsy Wound
Oral Biopsies: Evaluation of the Post-surgical Discomfort
Aim of this study is to evaluate the post-operative course in patients undergoing diagnostic or therapeutic oral mucosal biopsies.
- Conditions
- Quality of Life, Biopsy Wound, Surgical Wound, Healing Surgical Wounds
- Trial name
- NCT04514263
- Testing
- OHIP-14 Administration, VNS Administration
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Catholic University of the Sacred Heart
Infertility, Implantation Failure
Does Local Injury of the Endometrium Improve Controlled Ovarian Hyperstimulation (COH) + Intrauterine Insemination (IUI) Outcome?
It was previously demonstrated in in vitro fertilization (IVF) patients that local injury of the endometrium during a spontaneous menstrual cycle that precedes IVF treatment doubled the rates of implantation and pregnancy.
- Trial name
- NCT01111799
- Testing
- endometrial biopsy, natural cycle + IUI + endometrial biopsy
- Where
- Israel
- Volunteers
- 600 people
- Sponsor
- Meir Medical Center
Wound Healing, Cell Proliferation
Study to Assess on a Molecular Level the Influence of a 5 % Dexpanthenol Ointment in Subjects With Superficial Injuries
In previous in vitro studies it could be shown, that Dexpanthenol has an influence on the gene expression of fibroblasts. The genes which are influenced by Dexpanthenol play mainly a role during cell proliferating processes.The…
- Conditions
- Wound Healing, Cell Proliferation, Gene Expression
- Trial name
- NCT00859196
- Testing
- Dexpanthenol (BAY81-2996)
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bayer
Wound Healing
Wound Healing in Healthy Volunteers
The skin plays a critical role in protection where it acts as a barrier from damage and pathogens between the external and internal environments.
- Trial name
- NCT03433820
- Testing
- Observation of wound healing
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Centre for Human Drug Research, Netherlands
IgA Nephropathy (IgAN), Immunoglobulin A Nephropathy (IgAN)
Mechanistic Evaluation of Atrasentan in Patients With IgA Nephropathy (IgAN)
This multicenter, single-arm, open-label Phase 4 pilot study evaluates the effects of atrasentan added to optimized supportive care on kidney structure and function in adults with biopsy-confirmed IgA nephropathy.
- Trial name
- A-MECH (NCT07820995)
- Testing
- atrasentan
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Illinois Chicago
Diabetic Foot Ulcer, Diabetic Foot
Treatment of Diabetic Foot Ulcers With Inforatio Technique to Promote Wound Healing
This trial will examine the feasibility of conducting a definitive randomized clinical trial that tests whether inforatio technique will reduce time to healing of diabetic foot ulcers.
- Conditions
- Diabetic Foot Ulcer, Diabetic Foot, Wound Heal, Ulcer Foot
- Trial name
- NCT03985306
- Testing
- Inforatio technique
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Zealand University Hospital
Wound Closure Technique
A Comparison of Polyglactin 910 and Chromic Gut Suture in the Closure of Punch Biopsy Sites
Some Dermatologists prefer absorbable suture to non-absorbable suture in the closure of punch biopsy sites. The reason these are often preferred is because patients do not have to pay for another visit to get the suture material…
- Trial name
- NCT01722994
- Testing
- Polyglactin 910 sterile synthetic absorbable suture (Ethicon), Chromic Gut Sterile absorbable Suture (Ethicon)
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Mississippi Medical Center
Prostate Cancer, Locally Recurrent Cancer
Study on Prostate Salvage Using High-dose-rate Brachytherapy
A prospective, observational, multicenter study analyzing salvage treatment for prostate cancer-diagnosed via next-generation imaging (choline positron emission tomography (PET)/prostate-specific membrane antigen (PSMA) PET and…
- Conditions
- Prostate Cancer, Locally Recurrent Cancer, Biochemically Recurrent Prostate Carcinoma, Toxicity Radiation
- Trial name
- PROSCATE (NCT07860528)
- Where
- 10 sites in Spain
- Volunteers
- 63 people
- Sponsor
- Instituto de Investigación en Oncología Radioterápica - Fundación Española de Oncología Radioterápic
Biopsy Wound
Efficacy of Hydrocolloid Dressing vs. Topical Antibiotic on Wound Healing of Post-Punch Biopsy Wounds
The main objective of this study is to determine the efficacy of using hydrocolloid dressing on wound healing of post-punch biopsy wounds vs topical antibiotic.
- Trial name
- NCT07064161
- Testing
- Mupirocin (drug), Hydrocolloid Dressing (DuoDERM CGF)
- Where
- Philippines
- Volunteers
- 60 people
- Sponsor
- University of Santo Tomas Hospital, Philippines
Punch Skin Biopsy
Immediate Suture or Directed Wound Healing? Comparative Study of Their Respective Values Following a Punch Skin Biopsy (CICAT)
The skin punch-biopsies are frequently used technical acts in the current medical practice. However, while these skills are actually easy to perform, the subsequent healing procedure remains still poorly harmonized.
- Trial name
- CICAT (NCT04623372)
- Testing
- suture, directed wound healing
- Where
- France
- Volunteers
- 290 people
- Sponsor
- Centre Hospitalier le Mans
Chronic Liver Disease, Non-Alcoholic Fatty Liver Disease
Ultrasound Method to Measure Fibrosis of the Liver in Children
HYPOTHESIS: The investigators hypothesize that sonoelastography (SE) provide accurate quantitative measurements that can be used to stage liver fibrosis in pediatric patients with chronic liver disease.
- Conditions
- Chronic Liver Disease, Non-Alcoholic Fatty Liver Disease, HCV Coinfection, HBV
- Trial name
- NCT02086708
- Testing
- Shear Wave sonoelastography
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Virus Disease
Collection of Liver Tissue for Virologic Studies
This study will examine liver tissue to investigate the role of viral infections in fulminant hepatitis, liver failure, and profound bone marrow failure.
- Trial name
- NCT00005936
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Biopsy Wound, Endometrial Hyperplasia
Effect of Stress Ball Use on Anxiety Level During Endometrial Biopsy Procedure
The aim of this study is to determine the effect of stress ball application on the anxiety level during the endometrial biopsy procedure. This research is planned as a randomised controlled study.
- Conditions
- Biopsy Wound, Endometrial Hyperplasia, Endometrial Neoplasms
- Trial name
- NCT06171581
- Testing
- stress ball, control
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Acute Kidney Injury, Kidney Failure Chronic
French AKI Registry (FAKIR): A Multicenter Study on the In-Hospital Management and Outcomes of Severe Acute Kidney Injury in Nephrology Units
Acute Kidney Injury (AKI) is a common and serious condition in hospitalized patients, especially when it reaches stages 2 or 3 according to the KDIGO classification.
- Conditions
- Acute Kidney Injury, Kidney Failure Chronic, Cardiorenal Syndrome, Renal Replacement Therapies
- Trial name
- FAKIR (NCT07123324)
- Volunteers
- 750 people
- Sponsor
- University Hospital, Strasbourg, France
Wound Heal, Oral Dryness
Assessing the Efficacy of a Carbamide Peroxide Mouthwash for Oral Wound Healing, Oral Hygiene and Xerostomia Relief
The aim of this study is to evaluate the efficacy and safety of a carbamide peroxide mouthwash regarding oral wound healing, postoperative symptoms, xerostomia (dry mouth) and oral hygiene improvement.
- Conditions
- Wound Heal, Oral Dryness, Postoperative Pain, Sjogren's Syndrome
- Trial name
- NCT06363955
- Testing
- Carbamide Peroxide Mouthwash
- Where
- Greece
- Volunteers
- 54 people
- Sponsor
- National and Kapodistrian University of Athens
Wounds and Injuries
Feasibility Study for Fibroblast Autologous Skin Grafts
This research is being done to determine if investigators can change skin from one type to another. Specifically, investigators are interested in making normal skin into the thicker skin found on our palms and soles.
- Trial name
- NCT01964859
- Testing
- autologous skin fibroblasts, Filler Product
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Heart Transplantation, Graft Rejection
ZeroHeart Biopsy - Prediction of Deceased Donor Heart Transplant Performance From Organ Donors Using Pre-Transplant Biopsies - A Pilot Study
The goal of this observational study is to evaluate whether molecular analysis of donor heart biopsies taken at the time of organ removal ("Time Zero") can help predict the future function and rejection risk of the transplanted…
- Conditions
- Heart Transplantation, Graft Rejection, Myocardial Injury, Organ Preservation
- Trial name
- ZeroHeart (NCT06982404)
- Testing
- Time Zero Donor Heart Biopsy for Molecular Analysis
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna