Clinical trials: Biosensor
Pneumocystis Pneumonia
Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii
The main objective of the proposed research is to identify Pneumocystis jirovecii mutant strains on 4 genes encoding therapeutic targets such as dihydropteroate synthase (DHPS), dihydrofolate reductase (DHFR), cytochrome b (CYB)…
- Trial name
- DDBIOS (NCT06431958)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Brest
Rett Syndrome
ASSESSING EMERALD AND MC10 BIOSTAMP nPOINT BIOSENSORS FOR RETT SYNDROME
This is a pilot study of the Emerald device in Rett syndrome patients diagnosed with a confirmed MECP2 mutation. MC10 BioStamp nPoint patches will also be assessed with the goal to develop Rett-specific breathing algorithms
- Trial name
- NCT04514549
- Testing
- Emerald
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Rett Syndrome Research Trust
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
A Wearable Biosensor Patch for Non-Invasive Monitoring for Patients Undergoing Abdominal or Chest Surgery
This clinical trial tests the feasibility and safety of a wearable biosensor patch for non-invasive monitoring for patients undergoing abdominal or chest surgery.
- Trial name
- NCT07612085
- Testing
- Biospecimen Collection, Electronic Health Record Review, Interview
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- City of Hope Medical Center
Pulmonary Disease, Chronic Obstructive
Method Validation Study to Explore the Sensitivity of SenseWear Armband Gecko for Measuring Physical Activity in Subjects With Chronic Obstructive Pulmonary Disease (COPD) & Asthma
The prevalence, low cost, and low burden of wearable devices that provide quantitative and qualitative feedback on a subject's activity level present an opportunity for the use of these devices in clinical and observational…
- Trial name
- NCT02619357
- Testing
- SenseWear Armband Gecko, SenseWear Armband MF, Actigraph GT9x wristband and waistband
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- GlaxoSmithKline
Ischemia, Blood Circulation Disorder
New Method for Real-time Detection of Tissue Ischemia (ISCALERT)
This is a prospective, single arm, open, single centre clinical investigation designed to examine the feasibility and safety of the IscAlert™ device in patients scheduled for limb (arm/leg) surgery with tourniquet.
- Conditions
- Ischemia, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- ISCALERT (NCT04879875)
- Testing
- IscAlert, IscAlert 72h
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
General Surgery
Using Fitbit to Monitor Ambulation in Patients After Surgery.
This study will evaluate whether information on postoperative ambulation from Fitbits can improve surgeons' ability to monitor ambulation and identify patients at risk for prolonged length of stay, 30-day readmissions, and…
- Trial name
- NCT02741895
- Testing
- Fitbit monitoring
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Cedars-Sinai Medical Center
Ischemia, Blood Circulation Disorder
Detecting Tissue Ischemia in Reconstruction Flaps by a Novel CO2 Biosensor (DIMENSION-study)
The investigators will test if changes in CO2 is detected postoperatively in ischemic tissue in a reconstructed flap. IscAlert is measuring continuously CO2 in muscular and subcutaneous tissue.
- Conditions
- Ischemia, Blood Circulation Disorder, Biosensing Techniques, Surgery
- Trial name
- DIMENSION (NCT05487820)
- Testing
- IscAlert
- Where
- Norway
- Volunteers
- 160 people
- Sponsor
- Oslo University Hospital
COPD Exacerbation, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection
Study on Home Obstructive Respiratory Exacerbations
Strados Labs has developed the Strados™ Respiratory Care Platform, including the RESP™ Biosensor System, which encompasses a clinically validated wearable, non-invasive, Bluetooth-enabled device capable of remotely collecting…
- Conditions
- COPD Exacerbation, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection, COPD Exacerbation Acute, COPD
- Trial name
- SHORE (NCT06544928)
- Testing
- RESP™ Biosensor
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Strados Labs, Inc.
Parkinson´s Disease
Study to Evaluate the Impact of Using Wearable Devices in Addition to Standard Clinical Practice on Parkinson´s Subject Symptoms Management
Evaluate the benefits of Kinesia-360™ wearable technology in addition to standard clinical practice on improving Parkinson´s disease motor symptoms, Neupro dosing regimen and adherence to Neupro compared with only standard…
- Trial name
- NCT03103919
- Testing
- Kinesia-ONE™, Kinesia-360™, Rotigotine
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- UCB Biopharma S.P.R.L.
Wearable Devices
Wearable Devices for Early Detection of Postoperative Infection
This systematic review aims to evaluate the efficacy, accuracy, and clinical applicability of wearable infection detection wristbands in postoperative patients across ophthalmology, orthopaedic surgery, and general surgery.
- Trial name
- Wearable Wrist (NCT07334925)
- Testing
- White Blood Cell (WBC), C-reactive Protein (CRP)
- Where
- Egypt
- Volunteers
- 1,284 people
- Sponsor
- Benha University
Heart Failure
Evaluating Mobile Health Tool Use for Capturing Patient-centered Outcomes Measures in HF Patients
Heart Failure (HF) is a highly prevalent disease that also carries high morbidity and mortality. The Food and Drug Administration (FDA) recognizes the importance of developing patient-centric endpoints that are relevant to…
- Trial name
- NCT04191356
- Where
- 6 sites in United States, Singapore
- Volunteers
- 67 people
- Sponsor
- Biofourmis Singapore Pte Ltd.
Healthy
A Study of Continuous Heart Rate Monitoring in Healthy Participants
The main purpose of this study in healthy participants is to find out whether a heart rate monitor will accurately pick up changes in heart rate caused by 2 different medications (pseudoephedrine and metoprolol), on the…
- Trial name
- NCT04682184
- Testing
- Propranolol, Pseudoephedrine, Wearable Biosensor Patch Device
- Where
- Singapore
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Ischemic Heart Disease, Stable Angina
BioFreedom US IDE Feasibility Trial
The purpose of this study is to collect additional safety and effectiveness data for on the Biosensors BioFreedom™ BA9 Drug Coated Coronary Stent in patients with native, de novo coronary artery disease.
- Conditions
- Ischemic Heart Disease, Stable Angina, Unstable Angina, Silent Ischemia
- Trial name
- NCT02131142
- Testing
- BioFreedom drug coated coronary stent
- Where
- 13 sites in United States
- Volunteers
- 72 people
- Sponsor
- Biosensors Europe SA
Post Traumatic Stress Disorder
Using Adhesive Biosensor Patches to Characterize the Biochemical Phenotype in PTSD
A psychiatric diagnosis of post-traumatic stress disorder (PTSD) is currently based mainly on non-quantitative elements, such as interviews and subjective impressions.
- Trial name
- NCT04071132
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nadav Goldental
Diabetes Mellitus, Type 1
Biosensors for Open and Closed-loop Glycemia Control in T1D Patients With Insulin Pump
In T1D, the destruction of beta-pancreatic cells causes insulin deficiency and requires insulin therapy whose control remains complex: even with recent technologies of continuous measurement and monitoring of blood glucose (CGM)…
- Trial name
- DIABLO (NCT04081883)
- Testing
- Biosensor algorithm
- Where
- France
- Volunteers
- 1 people
- Sponsor
- University Hospital, Bordeaux
Sensory Science, Performance Assessment
Personalized Performance Optimization Platform
Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance.
- Conditions
- Sensory Science, Performance Assessment, Countermeasure Evaluation, Neurocognitive Function
- Trial name
- P-POP (NCT06979570)
- Testing
- AttentivU
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Inflammatory Small Bowel Disease
GI Fluids Collection for an Ex-Vivo Development of Ingestible Capsule Devices With Real Time Biosensors
Up to 500 subjects undergoing standard endoscopy / pouchoscopy, or having ileostomy or colostomy bags or having an ileal pouch and who meet the eligibility criteria will be enrolled to this study during up to three years at up to…
- Trial name
- CLARINET (NCT02797535)
- Testing
- Endoscopy procedures
- Where
- 2 sites in Israel
- Volunteers
- 66 people
- Sponsor
- Medtronic - MITG
COVID 19
Bio-reconfigurable Electronic Platform for Multiplex Detection of Viral Respiratory Pathogens
This project focuses on developing a cutting-edge electronic biosensor platform for highly sensitive and specific detection of target biomolecules, with initial applications targeting SARS-CoV-2 detection.
- Trial name
- BIOPLEX (NCT06702540)
- Testing
- Biosensor chip
- Where
- Italy
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Alcohol Drinking, Alcohol Intoxication
Towards a Wearable Alcohol Biosensor: Examining the Accuracy of BAC Estimates From New-Generation Transdermal Technology Using Large-Scale Human Testing and Machine Learning Algorithms
The study will employ a combined laboratory-ambulatory design. Participants will engage in ambulatory assessment over the course of 14 days, wearing biosensors assessing transdermal alcohol concentration (TAC) and providing…
- Trial name
- NCT05692830
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Diabetes
A Feasibility Study to Assess Critical Aspects of Fluorescence Affinity Sensor (FAS) Performance and Safety Over Several Hours
The goal of this clinical research study is to learn about a new minimally invasive glucose monitoring device called Fluorescence Affinity Sensor (FAS).
- Trial name
- FAS (NCT01065948)
- Testing
- Subcutaneous glucose monitoring device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- BioTex, Inc.