Clinical trials: Biosensor
Pressure Injuries, Skin Failure
Barrier Functions oF Skin in ICU: SKIN-BAR
This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration…
- Conditions
- Pressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
- Trial name
- SKIN-BAR (NCT07560683)
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Koç University
Ischemia, Blood Circulation Disorder
New Method for Real-time Detection of Tissue Ischemia
This is a prospective, single arm, open, single centre clinical investigation designed to examine the feasibility and safety of the IscAlert™ device in patients scheduled for limb (arm/leg) surgery with tourniquet.
- Conditions
- Ischemia, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- ISCALERT (NCT04893473)
- Testing
- IscAlert
- Where
- Norway
- Sponsor
- Oslo University Hospital
Ischemia Limb, Blood Circulation Disorder
Ischemia Detection During Development of Acute Compartment Syndrome
This is an open, observational, prospective, descriptive, single-centre study including 60 patients. The study is designed to investigate if IscAlert sensor system can be used for reliable and continuous tissue carbon dioxide…
- Conditions
- Ischemia Limb, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- IDEA (NCT06079255)
- Testing
- IscAlert sensor(s) in patient with risk of acute compartment syndrome
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Sars-CoV2
Rapid Detection of COVID-19 by Portable and Connected Biosensor
The objective of study is to estimate the sensitivity and specificity of the COR-DIAL based on nasopharyngeal samples taken at the patient's admission in relation to the final diagnosis of COVID-19 made by the medical team.
- Trial name
- COR-DIAL-1 (NCT04367142)
- Testing
- COVID-19 RT-PCR, Biosensor
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Lille
Epilepsy, Tonic-Clonic
Embrace and Quality of Life
A prospective, open, randomized, pilot clinical trial which aims the assessment of quality of life (QOL) in epilepsy outpatients equipped with a wrist-worn biosensor that provides measures of electrodermal activity and…
- Trial name
- EMBQL (NCT03831802)
- Testing
- Embrace with Alert and Mate apps, Embrace with Mate app only
- Where
- Switzerland
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Concussion, Mild
Rapid, Accurate, Cost-effective Assessment of Blood Biomarkers for Diagnosis of Concussion
The goal of this observational study is to test if a biosensor can accurately measure a blood biomarker in adult patients presenting to the emergency department with concussion.
- Trial name
- RACE (NCT05588115)
- Where
- Canada
- Volunteers
- 225 people
- Sponsor
- University of Calgary
Hypertension
Sodium Healthy Living Project
Subjects will participate in a 12-week church-based intervention with five separate components: 1) participation in weekly group sessions; 2) daily use of Fitbit activity tracker; 3) daily, twice a day blood pressure monitoring…
- Trial name
- SoHELP (NCT03027791)
- Testing
- Virtual Reality, Group Sessions
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Lung Cancer, Breast Cancer
Non Invasive Detection of Lung and Breast Cancer by Odor Signature
The investigators have developed an early detection solution for lung and breast cancer. A system which can distinguish between different medical odors based on biosensors.
- Trial name
- NCT02195076
- Testing
- non-invasive detection of cancer odor
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- BioSense Medical LTD
Pancreatic Cancer
Biomarkers of Pancreatic Cancer and New Way to Detection
Amphoteric regulatory protein (AREG), a member of epidermal growth factor (EGF) family, is expressed in many tumors.Our study confirmed that the expression of AREG in the serum of patients with pancreatic cancer is significantly…
- Trial name
- NCT04549064
- Testing
- diagnosis of pancreatic cancer
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Physiological Parameters
Monitoring of Patient Physiological Parameters in Real Life Using OXYFLEX® Biosensors Versus Standard Monitoring
The purpose of this study is to use the OXYFLEX® device in real care conditions during the hospital management of a population of patients from various hospital services.
- Trial name
- OXYVIVO (NCT07037784)
- Testing
- Continuous monitoring of vital constants with OXYFLEX® biosensor.
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Preeclampsia
Mindfulness and Wearable Biosensors to Prevent Hypertensive Disorders of Pregnancy
The MINDBP study will enroll 90 pregnant women at risk for HDP across two sites (MCW and Brown) and randomize them to: (1) mindfulness training (MT) plus wearable biosensors, (2) MT alone, or (3) routine prenatal care.
- Trial name
- MINDBP (NCT07218237)
- Testing
- Mindfulness training, Garmin Vivoactive 4 watch
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Medical College of Wisconsin
Lithium Level Detection in Sweat
Indirect Evaluation of Lithium Level in Blood Using Non-invasive Sweat Biosensors
Indirect evaluation of the accuracy and the efficacy of biosensors developed for Li+ detection in sweat.
- Trial name
- NCT04186507
- Testing
- Smartwatch with integrated Li+ sensor (provided by Spectrophon LTD)
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Tirat Carmel Mental Health Center
Pulse Oximetry
Mobile Biosensor for Measuring Vital Signs in Healthcare and Home Settings
This study will record vital signs (heart rate and blood oxygen levels) using a new cell phone integrated biosensor and compare it to routine measurements carried out in the clinics and hospital at UCSD.
- Trial name
- NCT04233827
- Where
- United States
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Ischemia, Blood Circulation Disorder
Early Discovery of Ischemia After Replantation Surgery of the Extremities
Investigators will test if changes in CO2 is detected postoperatively in ischemic tissue in a replanted extremity of a traumatically amputated upper or lower extremity.
- Conditions
- Ischemia, Blood Circulation Disorder, Carbon Dioxide, Biosensing Techniques
- Trial name
- EDIR (NCT05297266)
- Testing
- IscAlert
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Oslo University Hospital
Validation, Biosensors
Validation of New G6PD Point of Care Tests Against Gold Standard Quantitative
This is a laboratory research to evaluate performances of quantitative POC G6PD tests (Biosensors) against gold standard quantitative laboratory based tests and genotyping.
- Conditions
- Validation, Biosensors, Genotyping
- Trial name
- Biosensors (NCT02625285)
- Where
- Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Urinary Bladder Neoplasms
Molecular Biosensors for Detection of Bladder Cancer
This project focuses on developing specific and sensitive detectors of biomarker-based signatures associated with diagnosed and recurrent bladder cancer.
- Trial name
- NCT02957370
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- University of California, Irvine
Celiac Disease
A Decentralized Home-Based Study To Investigate Novel Objective Biomarker Of Gluten-Mediated Symptoms In Celiac Disease Participants (CeDar ROSE Study)
This is a decentralized study to primarily explore a novel objective digital biomarker (i.e., Gluten Dependency Index) for celiac disease-related responses triggered by gluten exposure using a wearable biosensor.
- Trial name
- NCT05686369
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Chugai Pharmaceutical
Cardiac Arrest, Out-Of-Hospital, Hypotension and Shock
BCG Biosensor and Non- and Invasive Monitoring During Emergency Medicine Cases, a Prospective Feasibility Study
In a out of hospital emergency medicine study the investigators will measure hemodynamic effects of implemented treatments for patients with cardiac arrest, hypotension, and intensive care transports.
- Trial name
- NCT04891380
- Testing
- LUCAS 2 Active Decompression 2, Hypotension, Intensive care transport
- Where
- Norway
- Volunteers
- 183 people
- Sponsor
- Oslo University Hospital
Autonomic Dysfunction, Autonomic Imbalance
Non-Invasive Bioelectronic Analytics
Biomarkers can be evaluated to provide information about disease presence or intensity and treatment efficacy. By recording these biomarkers through noninvasive clinical techniques, it is possible to gain information about the…
- Conditions
- Autonomic Dysfunction, Autonomic Imbalance, Autonomic Nervous System Diseases, Vagus Nerve Autonomic Disorder
- Trial name
- NIBA (NCT04100486)
- Testing
- Standing-Squatting-Standing Test, Deep Breathing Test, Cold Pressor Test
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Endometriosis
Objective Pain Measurement Using a Wearable Biosensor and a Mobile Platform in Patients With Endometriosis
This study aims to explore a novel objective measurement for endometriosis-related pain. A variety of pain symptoms are associated with endometriosis, including dysmenorrhea, dyspareunia, dysuria, dyschezia and chronic pelvic…
- Trial name
- OPINE (NCT04318275)
- Where
- 7 sites in United States, Singapore and 1 more
- Volunteers
- 90 people
- Sponsor
- Biofourmis Singapore Pte Ltd.