Clinical trials: Biosensor
Breast Cancer
Nipple Secretion Samples in Detecting Breast Cancer in Patients and Healthy Participants Undergoing Breast Cancer Screening, Breast Diagnostic Studies, or Treatment for Benign Breast Disease
RATIONALE: Diagnostic procedures that measure biomarker levels in nipple section and blood samples, may help in the early detection of breast cancer.
- Trial name
- NCT00813878
- Testing
- protein analysis, protein expression analysis, proteomic profiling
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- City of Hope Medical Center
Pediatric Respiratory Diseases, Asthma
Analysis of Lung Sounds Collected by RESP Biosensor to Support Decision Making in Monitored Hospitalized Pediatric Patients
This observational clinical trial is designed to confirm whether RESP™ Biosensor could be deployed to support clinical decision making in challenging pediatric cases, minimize clinician-to-clinician variability in lung sound…
- Conditions
- Pediatric Respiratory Diseases, Asthma, RSV Infection, COVID-19
- Trial name
- NCT05661422
- Testing
- RESP™ Biosensor
- Where
- United States
- Sponsor
- Strados Labs, Inc.
Gastro Intestinal Bleeding
Detection of Gastrointestinal Bleeding in Intensive Care Patients Via Biosensor Watch
The purpose of this study to improve methods of monitoring and diagnosing gastrointestinal bleeding via the E4 wristband, a biosensor watch.
- Trial name
- NCT03874169
- Testing
- E4 wristband
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Columbia University
Stroke, Vascular Severe Brain Injury
Blood Extracellular Vesicles as Predictive Recovery Biomarker After Stroke and Brain Injury
The rehabilitation outcome and recovery, in people after stroke or with vascular severe brain injury(vSBI), are difficult to predict.
- Conditions
- Stroke, Vascular Severe Brain Injury, Rehabilitation
- Trial name
- PRISMA (NCT06871800)
- Testing
- blood withdrawal
- Where
- 3 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Psychological Stress, Anxiety
NeuroFinance Human Stress Trial During Financial and Informational Volatility
The NeuroFinance Human Stress Trial (NFHST-2026-001) is a decentralized observational clinical study designed to evaluate how financial market volatility, economic uncertainty, digital media exposure, and information-driven…
- Conditions
- Psychological Stress, Anxiety, Emotional Stress, Autonomic Nervous System Dysfunction
- Trial name
- NFHST (NCT07622589)
- Testing
- Wearable Physiologic Monitoring Platform
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Respiratory Failure, Covid19
COVID-19 Advanced Respiratory Physiology (CARP) Study
The anticipated second wave of COVID-19 cases will present healthcare system challenges, including requirement to monitor large numbers of patients for deteriorating respiratory failure.
- Conditions
- Respiratory Failure, Covid19, Biosensor
- Trial name
- CARP (NCT04668313)
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- NHS Greater Glasgow and Clyde
Alcohol Intoxication
Development of LabPatch-alcohol as a Noninvasive Skin Patch to Detect Blood Alcohol Concentrations
This study is designed to test LabPatch-alcohol, a wearable, non-invasive biosensor Band-Aid like patch that is designed to detect real-time changes in interstitial alcohol concentrations in human subjects.
- Trial name
- NCT03242161
- Testing
- LabPatch-alcohol
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Cushing Syndrome, Primary Aldosteronism
Continuous Steroid Monitoring in Interstitial Fluid With Wearable and Nanoparticle-enhanced Biosensors for Improved Management of Adrenal Disorders
The goal of this project is to provide novel technology that will pave the way from the present single-point (analogue) endocrinology towards continuous cortisol and aldosterone monitoring with full time resolution.
- Conditions
- Cushing Syndrome, Primary Aldosteronism, Adrenal Insufficiency
- Trial name
- NCT06980753
- Testing
- Participants will use the biossensor for 48 h
- Where
- Brazil
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Bruxism, Sleep
OstiSense Biosensor in Bruxism Reduction - A Clinical Study
The overall objective of the clinical studies with the OstiSense biosensor tool will be to evaluate whether the use of the OstiSense biosensor tool significantly reduces the number of sleep bruxism events per night as well as the…
- Trial name
- NCT03749928
- Testing
- OstiSense biosensor - active, OstiSensor biosensor - not activated
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Chronic Obstructive Pulmonary Disease, Healthy
Biosensor and Environmental Sensor Development Within the REMEDIA Project
The aim of this proof-of-concept study is to obtain data that will contribute to the development of sensor devices (biosensor and environmental sensor) for patients with lung diseases (e.g. COPD).
- Trial name
- NCT06035276
- Testing
- Exposure to clean air, Exposure to urban air
- Where
- Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fraunhofer-Institute of Toxicology and Experimental Medicine
Rett Syndrome
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials.
- Trial name
- VIBRANT (NCT06338267)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Rett Syndrome Research Trust
Diabetes Mellitus
Measurement Algorithm Control and Optimization With Subsequent Performance Evaluation of Sanmina Non-invasive Biosensors During a Standardized Meal Test in Patients With Diabetes Mellitus Type 1 and Type 2
Measurement algorithm control and optimization with subsequent performance evaluation of Sanmina biosensors in monitoring of glucose, heart rate (HR), and SpO2 in patients with type 1 and type 2 diabetes during a standardized…
- Trial name
- NCT04379427
- Testing
- Sanmina Biosensor
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sciema UG
Obsessive-Compulsive Disorder
A Wearable AI Feedback Tool for Pediatric OCD
To test the feasibility of implementing digitally enhanced psychotherapy and research in a community child and adolescent mental health center including the acceptability of the digital technology to patients, parents and…
- Trial name
- NCT05064527
- Testing
- wearable biosensor, Treatment as usual (TAU), Exposure and response prevention (ERP)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Cancer, Cancer, Metastatic
Digitally-Captured Step Counts for Evaluating Performance Status in Advanced Cancer Patients
The purpose of this study is to examine the relationships between objectively measured physical activity and provider-assessed and patient-reported functional outcomes in patients with advanced cancer.
- Conditions
- Cancer, Cancer, Metastatic, Neoplasms
- Trial name
- DigiSTEPS (NCT03757182)
- Testing
- Wearable activity monitor
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Cedars-Sinai Medical Center
HIV Infections, Substance Use Disorders
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance Users (PrEPSteps)
This study will deploy a novel, personalized, smartphone-based intervention (PrEPSteps) that responds to real-time PrEP adherence and nonadherence detected through the use of a digital pill.
- Trial name
- PrEPSteps (NCT03512418)
- Testing
- PrEPsteps, Digital pill, Truvada
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Adolescent Idiopathic Scoliosis (AIS)
Wireless EMG-Based Monitoring of Paraspinal Muscle Activation in Adolescent Idiopathic Scoliosis
This study aims to develop and evaluate a wireless, non-invasive, embedded electromyography (EMG) system for monitoring paraspinal muscle activation asymmetries in adolescents with idiopathic scoliosis.
- Trial name
- AIS-EMG (NCT07738588)
- Testing
- Wireless Embedded Surface EMG (sEMG) Measurement System
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ertugrul Deniz Kose
SARS-CoV Infection, Covid19
Rapid Detection of COVID-19 by Portable and Connected Biosensor : Biological Proof of Concept
The main objective of this CorDial-S proof-of-concept study is to evaluate the ability to detect COVID-19 infection in nasopharyngeal swabs with CorDial-S and compare it to the PCR technique currently in use.
- Trial name
- COR-DIAL-S (NCT04780334)
- Testing
- COVID-19 RT-PCR, Biosensor
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Lille
Covid19
Detection of COVID-19 Decompensation
In this study we will be monitoring for patient events (emergency department admission, hospital admission, admission to an observation unit, or death) and evaluating the feasibility and utility of using pinpointIQ in the…
- Trial name
- DeCODe (NCT04575532)
- Testing
- Use of the pinpointIQ solution (physIQ, Inc.)
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- physIQ, Inc.
Diabetes, Diabetes Mellitus, Type 1 Diabetes
Argus 2.0 Adoption Study
This study evaluates the usability of the KOS Argus Continuous Glucose Monitoring (CGM) System, a noninvasive, wrist-worn device that estimates blood glucose levels using light-based sensors and artificial intelligence…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1 Diabetes, Diabetes Mellitus, Type 2, Prediabetes
- Trial name
- NCT07425236
- Testing
- KOS Argus Continuous Glucose Monitoring System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- KOS Inc.
Neutropenia, Febrile, Cancer
Remote Monitoring of Patients at Risk of Sepsis
Chemotherapy is used to treat cancer in many thousands of patients per annum in the United Kingdom and millions worldwide. Most chemotherapy suppresses bone marrow function and causes a low white cell count (neutropenia) which is…
- Conditions
- Neutropenia, Febrile, Cancer, Sepsis
- Trial name
- REACT (NCT04260230)
- Testing
- Lifetemp/Lifetouch sensors
- Where
- United Kingdom
- Sponsor
- The Christie NHS Foundation Trust