Clinical trials: Bipolar Affective Disorder
Bipolar Depression, Bipolar Disorder
Low Field Magnetic Stimulation Treatment for Bipolar Depression
Individuals with bipolar depression who had a particular kind of brain imaging reported improved mood after the imaging. This effect may be linked to the changing magnetic fields used during these magnetic resonance imaging…
- Conditions
- Bipolar Depression, Bipolar Disorder, Depression
- Trial name
- NCT00217217
- Testing
- Echo-Planar Magnetic Resonance Imaging (EP-MRSI)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mclean Hospital
Depression, Bipolar
Lithium Versus Cariprazine in the Acute Phase Treatment of Bipolar Depression (DUAG9)
The goal is to study the effect of lithium compared to cariprazine in patients with depression in a bipolar disease. The main question it aims to answer is: Difference in change between the two groups from baseline to after 8…
- Trial name
- DUAG9 (NCT05913947)
- Testing
- Lithium, Cariprazine
- Where
- Denmark
- Volunteers
- 122 people
- Sponsor
- Aalborg University Hospital
Schizophrenia, Bipolar I Disorder
ERG Components in Schizophrenia and Bipolar Disorder Type I
This study will further assess ERG components obtained with different ERG devices, to be considered in a prediction model for each diagnosis.
- Trial name
- NCT03788811
- Testing
- ERG assessment (RSPA)
- Where
- 19 sites in United States, Australia and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- diaMentis Inc.
Bipolar Disorder
A Six-Week Study Evaluating The Efficacy And Safety Of Geodon In Patients With A Diagnosis Of Bipolar I Depression
This is a 6-week trial that evaluates the efficacy and safety of Geodon (ziprasidone) in outpatient subjects ages 18 and older with Bipolar Disorder type I, depressed.
- Trial name
- NCT00141271
- Testing
- Geodon (Ziprasidone)
- Where
- 72 sites in United States
- Volunteers
- 536 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Bipolar Disorder in Remission
rTMS-tACS Stimulation on Improving Cognitive Function in Bipolar Disorder
Based on the individualized positioning technology of diffusion tensor imaging (DTI), the purpose of this study is to explore a new stimulation target and protocol for the treatment of bipolar disorder in remission through the…
- Trial name
- NCT05964777
- Testing
- rTMS（repeated transcranial magnetic stimulation）, tACS（transcranial alternating current stimulation）
- Where
- China
- Volunteers
- 116 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Catatonia, Schizophrenia
Personalized Prospective Study Evaluation of the Efficacy and Safety of Noninvasive Neuromodulation of TMS in Subjects With Catatonia
Evaluation effectiveness and safety of TMS in subjects with catatonia
- Conditions
- Catatonia, Schizophrenia, Schizo Affective Disorder, Bipolar Affective Disorder
- Trial name
- RECATA (NCT06176456)
- Testing
- rTMS
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Moscow Psychiatric Hospital No. 1 Named after N.A. Alexeev
Diabetes, Asthma
Integrated Care (IC) Models for Patient-Centered Outcomes
Multiple chronic conditions (MCC) are widely recognized as the U.S. public health challenge of the 21st century. These physical and behavioral health conditions take a large toll on those living with chronic diseases, including…
- Conditions
- Diabetes, Asthma, Chronic Obstructive Pulmonary Disease, Hypertension
- Trial name
- IC (NCT03451630)
- Testing
- High-Touch, High-Tech, Optimal Discharge Planning
- Where
- United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Schizophrenia, Major Depressive Disorder (MDD)
A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode
The purpose of this study is to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple dose oral administration of SEP-380135 in participants with schizophrenia or with a major depressive…
- Conditions
- Schizophrenia, Major Depressive Disorder (MDD), Bipolar Disorder
- Trial name
- NCT07549581
- Testing
- SEP-380135
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Inflammatory Bowel Diseases, Depressive Episode
Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on Health
This study is a large population-based analysis in the United Kingdom (UK) using routine primary care data to investigate the impacts on quality-of-life outcomes and use of healthcare services in people aged 5 - 25 years…
- Conditions
- Inflammatory Bowel Diseases, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorder
- Trial name
- NCT05206734
- Testing
- No specific intervention
- Where
- United Kingdom
- Volunteers
- 19,469 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Bipolar Disorder
Risk Factors for Development of Rapid Cycling in Bipolar Disorder Patients
In this study we tried to elucidate the factors associated with the development of a rapid cycling course in bipolar disorder patients, in a prospective and longitudinal design, and the role of antidepressants.
- Trial name
- NCT01992302
- Where
- Spain
- Volunteers
- 289 people
- Sponsor
- Hospital Clinic of Barcelona
Severe Mental Disorder, Schizophrenia
Community-based Mental Health Care for People With Severe and Enduring Mental Ill Health (RECOVER-E) Croatia
To contribute to improving the level of functioning and quality of life and mental health outcomes for people with severe and enduring mental ill health (SMI) (schizophrenia, bipolar disorder, depression) by adapting and up…
- Conditions
- Severe Mental Disorder, Schizophrenia, Bipolar Disorder, Severe Depression
- Trial name
- RECOVER-E (NCT03862209)
- Testing
- Community mental health team
- Where
- Croatia
- Volunteers
- 200 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Bipolar Disorder
Research Study of Bipolar Mood Symptoms and Cognitive Problems
This is a sixteen week, randomized, double-blind add-on study of valacyclovir versus placebo in approximately 60 outpatients meeting diagnostic criteria according to the Diagnostic and Statistical Manual of Mental Disorders (DSM)…
- Trial name
- NCT00428298
- Testing
- Valacyclovir
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Bipolar Depression
Aripiprazole Treatment of Bipolar Depression
This is a study of addition of aripirazole to the treatment of bipolar depressed patients who are not better on the medications that they are currently receiving.
- Trial name
- NCT00198198
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
Anxiety, Depression
Ginger.io Behavioral Health Study
This Study will evaluate the impact of a smartphone-based platform on a range of outcomes for medically-underserved patients with mood disorders (e.g.
- Conditions
- Anxiety, Depression, Bipolar I Disorder, Bipolar II Disorder
- Trial name
- NCT02491307
- Testing
- Ginger.io Smartphone Application
- Where
- 4 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Community Health Center, Inc.
Bipolar Disorder
Adapting the Bipolar Care Model for Chronic Care Management in Community-based Health Care Sites
This study will determine if a version of the bipolar care model adapted for a nonresearch audience can improve patient health and correct use of the model in community-based mental health care sites.
- Trial name
- NCT00747201
- Testing
- Replicating Effective Programs Framework for the Bipolar Care Model, Bipolar Care Model Package Only
- Where
- 3 sites in United States
- Volunteers
- 384 people
- Sponsor
- University of Michigan
Bipolar I Disorder, Bipolar II Disorder
Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder
The goal of this clinical trial is to identify the specific characteristics (phenotypes) that may be useful to help select the right medication for weight loss, and to study the effect of individualized guided medication in…
- Conditions
- Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity
- Trial name
- OBOE-Mayo (NCT07213466)
- Testing
- Group Therapy Program, semaglutide, Phentermine-Topiramate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Bipolar Disorder
Treatment Study of Bipolar Depression
The purpose of this study is to determine whether a single intravenous administration of an N-methyl-D-aspartate antagonist is safe and effective for the acute treatment of bipolar depression.
- Trial name
- NCT00947791
- Testing
- ketamine, midazolam
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alzheimer Disease, Dementia With Lewy Bodies (DLB)
Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental Disorder
This is a retrospective observational study to evaluate the clinical utility of blood-based biomarkers in the diagnosis and management of patients with a neurodegenerative disease (ND) or mental disorder (MD).
- Conditions
- Alzheimer Disease, Dementia With Lewy Bodies (DLB), Frontotemporal Dementia (FTD), Major Depressive Disorder (MDD)
- Trial name
- Synapsing-BK (NCT07314190)
- Where
- Spain
- Volunteers
- 1,799 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Bipolar Disorder
Reward and Punishment Sensitivity in Bipolar Disorders
Bipolar disorder (BD) represents a chronic mood disorder and one of the leading causes of disability worldwide. Complexity of its clinical presentations leads to delayed diagnosis and difficult management in routine clinical…
- Trial name
- Recodec-BP (NCT04237610)
- Testing
- behavioral assessment
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Bipolar Disorder
Far Infrared Radiation Treatment for Bipolar Condition
A preliminary study to determine the possibility of using far infrared radiation for the treatment of the Bipolar Condition
- Trial name
- NCT00573196
- Testing
- Far infrared
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- GAAD Medical Research Institute Inc.