Clinical trials: Bipolar Disorder
Psychotic Disorder, Bipolar Disorder
Well Being And Resilience: Mechanisms of Transmission of Health and Risk
The purpose of this study is to establish a cohort of pregnant women with severe mental disorder and to identify biological and psycho-social transmission mechanisms involved in the development of 'risk' and 'resilience' in the…
- Conditions
- Psychotic Disorder, Bipolar Disorder, Depressive Disorder
- Trial name
- WARM (NCT02306551)
- Testing
- Biological and psycho-social risk and resilience factors
- Where
- 3 sites in Denmark, United Kingdom
- Volunteers
- 93 people
- Sponsor
- Susanne Harder
BIPOLAR I DISORDER
Efficacy and Safety of Eslicarbazepine Acetate (BIA 2-093) in Acute Manic Episodes Associated With Bipolar I Disorder
The primary study objective was to evaluate the dose-dependent efficacy of eslicarbazepine acetate administered at doses of 600, 1200, and 1800 mg over a 3-week period, compared with placebo, as therapy in patients with acute…
- Trial name
- NCT01824602
- Testing
- Eslicarbazepine acetate 1800 mg, Eslicarbazepine acetate 1200 mg, Eslicarbazepine acetate 600 mg
- Volunteers
- 38 people
- Sponsor
- Bial - Portela C S.A.
Bipolar Disorder, Depressive Disorder
Prediction on the Recurrence of Manic and Depressive Episodes in Bipolar Disorder
Mood disorders (including bipolar disorder and major depressive disorder) are chronic mental disorders with high recurrent rate. The more the number of recurrence is, the worse long-term prognosis is.
- Trial name
- NCT05828056
- Testing
- Wearable activity tracker
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Depression, Anxiety
The CARE (Collaborative Adolescent Running Experience) Project
This study is being completed to see if participants activity levels may have an impact as a treatment for depression, or depressive symptoms.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Bipolar Disorder
- Trial name
- CARE (NCT05837351)
- Testing
- Exercise -Running
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Bipolar Disorder
Dietary Intervention for Bipolar Disorder
Bipolar disorder (BD) is a chronic, often disabling illness, and many individuals remain symptomatic despite pharmacotherapy. Significant mood variability often persists throughout the lifespan and predicts relapse, leading to…
- Trial name
- NCT02272010
- Testing
- Experimental Diet, Comparator Diet
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Milton S. Hershey Medical Center
Bipolar II Disorder
Psilocybin Therapy for Depression in Bipolar II Disorder
The purpose of this study is to determine the safety, tolerability, and feasibility of psilocybin therapy in people with Bipolar II Disorder.
- Trial name
- BAP (NCT05065294)
- Testing
- Psilocybin therapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of California, San Francisco
Bipolar Depression
Ketogenic Intervention for Bipolar Depression
The purpose of this study is to assess the clinical correlates of therapeutic precision ketosis in bipolar depression and to evaluate the cardiometabolic correlates associated with therapeutic precision ketosis in bipolar…
- Trial name
- NCT07121894
- Testing
- Ketogenic Diet
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Bipolar Disorder
Pilot Study of the Effects of Circadian Rhythms on the Treatment of Bipolar I Depression.
The objective of this pilot study is to test the feasibility of a larger planned trial. The objective of this larger trial will be to determine the extent to which aspects of circadian rhythmicity, including, sleep/wake rhythms…
- Trial name
- Rhythms (NCT00726154)
- Testing
- IPSRT, Collaborative Care
- Where
- United States
- Sponsor
- University of Pittsburgh
Bipolar Disorder, Cardiovascular Disease
Self-Management Addressing Heart Disease Risk Trial
The purpose of this research study is to learn whether or not people with bipolar disorder can reduce their risk of heart disease and related conditions by having a Care Manager provide self management and care management.
- Trial name
- SMAHRT (NCT00499096)
- Testing
- Chronic care model for Bipolar Disorder
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- US Department of Veterans Affairs
Bipolar Disorder, Bipolar I Disorder
LiveWell: A Mobile Intervention for Bipolar Disorder
LiveWell is a study evaluating the use of smartphones to better understand and improve the treatment of bipolar disorder. Our goal is to increase access to psychosocial interventions and improve their effectiveness in reducing…
- Trial name
- NCT03088462
- Testing
- Psychiatric management, Psychosocial treatment, LiveWell Program
- Where
- 2 sites in United States
- Volunteers
- 205 people
- Sponsor
- Northwestern University
Bipolar Disorder
Acupuncture as a Supplemental Treatment for Bipolar Depression
The purpose of this study is to evaluate the effectiveness of acupuncture in the treatment of Bipolar Depression.
- Trial name
- NCT00071669
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Texas Southwestern Medical Center
Bipolar Disorder, Schizo Affective Disorder
Brain Stimulation and Cognitive Training
People with serious mental illness often report difficulties with thinking skills like memory. These difficulties can make it harder to perform day-to-day activities.
- Conditions
- Bipolar Disorder, Schizo Affective Disorder, Schizophrenia
- Trial name
- NCT03338673
- Testing
- tDCS, BrainHQ
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Borderline Personality Disorder, BPD
Examining Dose-Related Effects of Oxytocin on Social Cognition Across Populations
Social cognition impairment is critical to the pathology and morbidity of a number of psychiatric disorders, including the schizophrenia spectrum, the autism spectrum and the personality disorders, thus representing a dimension…
- Conditions
- Borderline Personality Disorder, BPD, Schizotypal Personality Disorder, SPD
- Trial name
- NCT02149823
- Testing
- Syntocinon 24 Intranasal Units (IU), Syntocinon 40 Intranasal Units (IU)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Maria de las Mercedes Perez Rodriguez
Metacognitive Capacities
Psychological Factors In The Treatment Of Bipolar Mood Disorders
The aim of this study is to trial an intervention targeting potential deficits in an individual's ability to form, and reflect upon, ideas about themselves and others (known as metacognitive capacities), specifically in relation…
- Trial name
- NCT03266679
- Testing
- Metacognitive Reflection and Insight Therapy - Adapted
- Where
- 2 sites in Australia
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Queensland University of Technology
Bipolar Disorder I, Bipolar Disorder II
PSYCHE (Personalised Monitoring SYstems for Care in Mental Health)
For the moment, the detection of a mood episode in Bipolar Disorder (BD) relies on the appearance of the first clinical signs that the clinician detect or that the patient becomes aware of and reports to the clinician.
- Conditions
- Bipolar Disorder I, Bipolar Disorder II, Rapid Cycling Bipolar Disorder(DSM-IV-TR)
- Trial name
- PSYCHE (NCT01879982)
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Strasbourg, France
Mood Disorders, Activities of Daily Living
Affective Disorders: Eliminate WArning Signs And REstore Functioning: AWARE
Affective disorders are associated with impaired functioning and quality of life, as well as comorbid somatic disorders and increased mortality.
- Conditions
- Mood Disorders, Activities of Daily Living, Quality of Life
- Trial name
- AWARE (NCT04701827)
- Testing
- AWARE intervention
- Where
- Denmark
- Volunteers
- 103 people
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Alcohol Dependence, Bipolar Disorder
Acamprosate vs. Placebo in Bipolar Alcoholics
To conduct a double-blind, randomized, placebo-controlled outpatient clinical trial of acamprosate in individuals with alcohol dependence and bipolar disorder who are also receiving mood stabilizing medication.
- Trial name
- NCT00466661
- Testing
- Acamprosate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical University of South Carolina
Depression - Major Depressive Disorder, Depression Bipolar
Right-sided 1-Hz Repetitive Transcranial Magnetic Stimulation (rTMS) Versus Left-sided Intermittent Theta Burst Stimulation (iTBS) in Patients With Depression
Aim: The purpose of the study is to establish the non-inferiority of right-sided inhibitory 1 Hz stimulation compared to left-sided intermittent theta burst stimulation (iTBS) in unipolar and bipolar depression.
- Trial name
- NCT07026461
- Testing
- repetitive transcranial magnetic stimulation, intermittent theta burst stimulation
- Where
- 2 sites in Sweden
- Volunteers
- 350 people
- Sponsor
- Region Örebro County
Bipolar Disorder Type II, Mood Depressive Disorder
Exploration of Differences in Metabolite Concentrations by NMR Spectroscopy in the Ventral Striatum, Anterior Cingulate Cortex and Prefrontal Cortex in Euthymic Patients With Unipolar and Bipolar Type II Mood Disorders, as Well as in Healthy Subjects
The presented project is an open and controlled single-center prospective exploratory study, evaluating the metabolic concentrations in the ventral striatum (VS), the Anterior cingulate cortex (ACC) and the prefrontal cortex…
- Trial name
- RMN-UNIBI (NCT05650788)
- Testing
- NMR spectrometry
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Urinary Bladder Neoplasm
Holmium Versus Bipolar en Bloc Transurethral Resection of Urothelium Tumor of the Urinary Bladder
En bloc resection of bladder tumors (ERBT) may improve staging quality and perioperative morbidity and influence tumour recurrence
- Trial name
- NCT04576286
- Testing
- Holmium versus Bipolar en bloc transurethral resection
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University