Clinical trials: Birth Control
Group B Strep Infection
Group B Streptococcus Response After Probiotic Exposure
This is an open-label randomized control trial and feasibility study designed to determine the feasibility of a larger RCT in our setting that would examine prenatal probiotic use in Group B Strep (GBS) positive pregnant women at…
- Trial name
- GRAPE (NCT04721912)
- Testing
- Probiotic dietary supplement
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of New Mexico
Contraception
Safety and Efficacy of CDB-2914 in Comparison to Levonorgestrel for Emergency Contraception
The purpose of this study is to assess the safety and efficacy of CDB-2914 in comparison to levonorgestrel for preventing pregnancy up to 5 days after unprotected sexual intercourse.
- Trial name
- NCT00551616
- Testing
- CDB-2914, Levonorgestrel
- Where
- 33 sites in United States, Ireland and 1 more
- Volunteers
- 2,221 people
- Sponsor
- HRA Pharma
Respiratory Distress Syndrome
A Multi-center Trial to Determine if Curosurf® Reduces the Duration of Mechanical Ventilation in Very Preterm Infants
The purpose of this study is to see if a medication called Curosurf can reduce the length of time that small premature babies with Respiratory Distress Syndrome (immature lungs) or RDS, stay on the ventilator, as compared to the…
- Trial name
- NCT01709409
- Testing
- Curosurf-Group1, BLES-group 2
- Where
- Canada
- Volunteers
- 88 people
- Sponsor
- Ottawa Hospital Research Institute
Obesity
A Study to Evaluate the Effect of the Experimental GLP-1 Drug PF-07081532 on Blood Levels of Common Birth Control Pills, and Drugs Omeprazole and Midazolam, and Effect of GLP-1 Drug Semaglutide on Midazolam Blood Levels in Healthy Adults With Weight in the Obesity Range
Two different groups of healthy volunteers will be chronically treated with GLP-1 drugs PF-07081532 or alternatively Semaglutide.
- Trial name
- NCT05671653
- Testing
- PF-07081532, Semaglutide
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pfizer
Contraception
LARC Forward Contraceptive Counseling at MHCC
This prospective randomized controlled study will evaluate if Long Acting Reversible Contraceptive (LARC) forward counseling in combination with same-day LARC placement increases overall LARC uptake within a community college…
- Trial name
- NCT02735551
- Testing
- Long Acting Reversible Contraception (LARC), Referral for Long Acting Reversible Contraception (LARC), Prescription for Short-Acting Hormonal Contraception
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Contraception
Study of the Safety, and Sperm and Gonadotropin Suppression of a Contraceptive Gel in Normal Men
To determine the number of men who have suppression of sperm production when using a daily regimen of Nestorone® Gel (0, 8 or 12 mg) and Testosterone Gel applied transdermally.
- Trial name
- CCN007 (NCT00891228)
- Testing
- Testosterone, Nestorone®
- Where
- 2 sites in United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Premier Research
Contraception
Synthetic vs Natural Estrogen in Combined Oral Contraception
The main objective of the study is to compare the metabolic effects of natural estradiol and synthetic ethinylestradiol used in combined oral contraception in healthy women.
- Trial name
- SYLVI (NCT02352090)
- Testing
- Ethinyl estradiol / dienogest, Estradiol valerate / dienogest, Dienogest
- Where
- 2 sites in Finland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Prevention of Pregnancy
Study of Safety and Efficacy of an Oral Contraceptive
This is a comparative study. The primary objective of the study is to assess the efficacy of a low dose oral contraceptive in the prevention of pregnancy.
- Trial name
- NCT00932321
- Testing
- Norethindrone Acetate/Ethinyl Estradiol 24 Days, Norethindrone Acetate /Ethinyl Estradiol 21 Days
- Where
- 34 sites in United States
- Volunteers
- 938 people, healthy volunteers welcome
- Sponsor
- Warner Chilcott
Smoking, Nicotine Addiction
The END Perioperative Smoking Pilot Study
The purpose of this pilot randomized trial is to determine the feasibility of e-cigarettes and telephone counselling (compared to transdermal nicotine replacement and telephone counselling) as a harm-reduction tool that may lead…
- Conditions
- Smoking, Nicotine Addiction, Surgery
- Trial name
- NCT02482233
- Testing
- ENDD (NJOY), NRT (NicoDerm CQ), telephone counseling
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Contraception, Prevention of Sexually Transmitted Infections
Evaluation of Polyurethane Male Condoms
The clinical study will compare two lubricated polyurethane male condoms of different thickness with a marketed lubricated control male condom made of natural rubber latex.
- Trial name
- NCT04622306
- Testing
- Control Latex Condom C, Polyurethane Condom A, Polyurethane Condom B
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sagami Rubber Industries Co., Ltd.
Contraception
Postplacental Intrauterine Device Insertion: A Mixed Methods Assessment of Women's Experience
The primary objective of this mixed methods pilot study is to understand women's experiences with postplacental intrauterine device (IUD) insertion through postpartum semi-structured interviews.
- Trial name
- PIPPI (NCT02312726)
- Testing
- Postplacental IUD insertion
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Intrauterine Devices, Cesarean Section
Immediate Postplacental Insertion of IUDs at Time of Cesarean Delivery: A Randomized Clinical Trial
This is a randomized controlled trial among women who deliver by cesarean at UNC Women's Hospital and desire an Intrauterine Device (IUD) for contraception postpartum.
- Trial name
- IUD@CSD (NCT01539759)
- Testing
- Immediate Postplacental Placement of an IUD during cesarean delivery
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of North Carolina, Chapel Hill
Obstetric Labour, Premature
The Safety, Tolerability And Metabolism Of GSK221149A, In Pregnant Women (30-36 Weeks), In Pre-Term Labor
Pre-Term Labor (prior to 37 weeks gestation) is the largest single cause of infant morbidity and mortality and is frequently associated with long-term disability. Oxytocin is a hormone produced by the body during labor.
- Trial name
- NCT00404768
- Testing
- GSK221149A
- Where
- 57 sites in United States, Argentina and 9 more
- Volunteers
- 93 people
- Sponsor
- GlaxoSmithKline
Pregnancy
Copper T380 IUD Versus Oral Levonorgestrel for Emergency Contraception vs. Plan B for Emergency Contraception
The purpose of this study is to see if women presenting for emergency contraception (EC) are willing to accept the copper intrauterine device (IUD).
- Trial name
- NCT00669396
- Testing
- Copper T380 IUD, levonorgestrel
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Utah
Contraception
Continuation of Subcutaneous and Intramuscular Depot Medroxyprogesterone Acetate in Post-abortion Patients
Multiple prior studies have compared self-administered Subcutaneous Depot Medroxyprogesterone Acetate(DMPA-SC) to both provider-administered DMPA-SC and Intramuscular Depot Medroxyprogesterone Acetate (DMPA-IM) and found that…
- Trial name
- NCT05505435
- Testing
- Depot-Medroxyprogestereone Acetate
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Respiratory Syncytial Virus Infections
A Study on the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine, in High Risk Pregnant Women Aged 15 to 49 Years and Infants Born to the Vaccinated Mothers
The purpose of this study was to evaluate the safety, reactogenicity and immune response of a single intramuscular dose of the respiratory syncytial virus (RSV) maternal vaccine compared to placebo, when administered in the…
- Trial name
- NCT04980391
- Testing
- RSV MAT
- Where
- 35 sites in United States, Brazil and 7 more
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Uterine Hemorrhage, Contraception
Does Concomitant Use of Combined Oral Hormonal Steroids Stop Bleeding in Women Using Etonogestrel Implants (Implanon/Nexplanon®)?: A Randomized Controlled Study
The specific aims are to determine if more women using Etonogestrel (ENG) contraceptive implants who report a bleeding-spotting episode of at least seven days will stop bleeding within 3 days of beginning a 14-day course of…
- Trial name
- NCT01968135
- Testing
- Combined Oral Contraceptive Pill
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Contraception, Adolescent Behavior
Reducing Adolescent Pregnancy in the Emergency Department
A multi-site randomized trial. Adolescents enrolled in this Clinical Trial will be enrolled into one of two arms. Adolescents in both arms will receive motivational interviewing enhanced counseling and a referral for follow up…
- Conditions
- Contraception, Adolescent Behavior, Emergency Department
- Trial name
- NCT04744155
- Testing
- Multi-Level Intervention, Enhanced Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Contraception
A Bioequivalence Study of IMPLANON and Radiopaque IMPLANON (34528)(P05720)
The primary purpose of this study is to demonstrate the bioequivalence of IMPLANON and Radiopaque IMPLANON.
- Trial name
- NCT00620464
- Testing
- Radiopaque Implanon, Implanon (etonogestrel implant)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Organon and Co