Clinical trials: Birth Outcomes
HIV Infections, Pregnancy Complications
Trial of Vitamins Among Children of HIV-infected Women
The purpose of this study is to examine the effects of multivitamin (B, C, E) supplementation on reducing the risk of morbidity and mortality outcomes among children born to HIV positive mothers, compared to placebo…
- Trial name
- NCT00197730
- Testing
- Multivitamins - vitamins B complex, C and E
- Where
- Tanzania
- Volunteers
- 2,387 people
- Sponsor
- Harvard School of Public Health (HSPH)
Anorectal Malformation, Hirschprung's Disease
Long-Term Health Outcomes in Children Born With Hirschsprung's Disease and Anorectal Malformations at the Colorectal Centre of Excellence in Quebec
The COCOE Registry is a long-term research registry based at the Montreal Children's Hospital Colorectal Centre of Excellence (COCOE) in Montreal, Quebec.
- Conditions
- Anorectal Malformation, Hirschprung's Disease, Colo-rectal Surgery, Fecal Incontinence
- Trial name
- NCT07603232
- Testing
- No intervention (observational study)
- Where
- Canada
- Volunteers
- 999 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Gestational Diabetes, Pregnancy Complications
Gestational Diabetes Monitoring and Management
The primary goal is to predict the clinical outcomes of mother and baby using blood glucose and other routinely collected clinical data in pregnancy to predict adverse outcomes at birth in women with GDM.
- Conditions
- Gestational Diabetes, Pregnancy Complications, Pregnancy in Diabetic, Pregnancy, High Risk
- Trial name
- NCT06963528
- Where
- United Kingdom
- Volunteers
- 1,800 people
- Sponsor
- University of Oxford
Pregnancy, Latent Phase
Hydrotherapy in Labor: Outcomes for Pain, Birth, and Breastfeeding
Warm showers are increasingly gaining attention for their positive impact on labor, yet studies on this topic in Turkey remain limited.
- Trial name
- HYDROTHERAPY (NCT07031635)
- Testing
- Hydrotherapy (Warm Shower)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Labor Pain
Analgesic Efficacy of a Multiport Versus Uniport Flexible Catheter for Labor Epidural Analgesia
The purpose of this study is to determine whether multiple ports improve the analgesic efficacy of flexible catheters used for the provision of epidural analgesia during the entire continuum of labor and delivery
- Trial name
- NCT01861821
- Testing
- Multiport flexible catheter, Uniport flexible catheter
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Baylor Research Institute
Pregnancy Related
Uterine Artery Doppler and 11-14 / 20-22 Weeks of Gestation Pregnancy
Uterine artery doppler measurements will be made at 11-14 weeks and 20-22 weeks of gestation, and the classification of these measurements according to type of delivery; and to investigate the change in the effect of delivery…
- Trial name
- NCT04248660
- Testing
- uterine artery doppler measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 750 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
HIV, Sickle Cell Disease
Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome
The investigators propose to adopt sustainable community networks (in this case churches) to implement an integrated community-based screening that incorporates mobile health technology (mHealth) to make prenatal test results…
- Conditions
- HIV, Sickle Cell Disease, Hepatitis B
- Trial name
- mHealth (NCT03027258)
- Testing
- mHealth
- Where
- Nigeria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Respiratory Disease
Hybrid Pulmonary Rehabilitation Study
Pulmonary rehabilitation is an exercise and education programme that helps improve breathlessness and quality of life for people living with lung and breathing problems.
- Trial name
- NCT05881590
- Testing
- Hybrid pulmonary rehabilitation
- Where
- United Kingdom
- Volunteers
- 69 people
- Sponsor
- Anglia Ruskin University
Advanced Age, Recurrent Pregnancy Loss(RPL)
Noninvasive Implantation Potential vs Morphology-Based Selection in IVF Single Blastocyst Transfer
Background: Morphology-based embryo selection cannot detect aneuploidy, which is common in advanced maternal age and recurrent pregnancy loss.
- Conditions
- Advanced Age, Recurrent Pregnancy Loss(RPL), Infertility (IVF Patients), Sequence Analysis
- Trial name
- NICSAI-SBT-RCT (NCT07461077)
- Testing
- NICS-AI, Morphology group
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pregnant HIV Positive Women, HIV
TB SCReening Improves Preventive Therapy Uptake in Pregnant Women With HIV
Because pregnant women have been excluded from clinical research, including tuberculosis (TB) research, little is known about diagnosing, treating and preventing TB in pregnant women.
- Conditions
- Pregnant HIV Positive Women, HIV, Tuberculosis (TB)
- Trial name
- TB SCRIPT-Moms (NCT07278453)
- Testing
- CRP screening (TB screening intervention arm), Deferred TPT (TPT delivery trial intervention arm)
- Where
- Uganda
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
User Experience With Virtual Assistants in Service Settings
Effects of Virtual Assistant Features on User Experience in Service Settings
This study examines how the characteristics and performance of virtual assistants influence user experience in service settings.
- Trial name
- AVir4Services (NCT07666295)
- Testing
- High Anthropomorphism, Low Anthropomorphism, Accurate Virtual Assistant Response
- Where
- Spain
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Malaga
ISS, SGA
Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.
This study is a randomized, open-label, active controlled, parallel group study comparing the efficacy and safety of once weekly Somatrogon to daily Growth Hormone (Genotropin) in pre-pubertal children with short stature either…
- Trial name
- MISSION (NCT07226089)
- Testing
- Somatrogon, Genotropin
- Where
- 32 sites in United States, France and 3 more
- Volunteers
- 254 people
- Sponsor
- Rabin Medical Center
Weight Gain, Anemia, Iron Deficiency
Egg Intervention During Pregnancy in Indonesia
The study consists of two arms: 1) intervention group using eggs as supplementary food given from 2nd trimester of pregnancy to birth, and 2) observational group of pregnant mothers.
- Conditions
- Weight Gain, Anemia, Iron Deficiency, Birth Weight, Birth Length
- Trial name
- PRECODE (NCT04694235)
- Testing
- Egg intervention
- Where
- Indonesia
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Preterm
Long Term Health Cohort of Premature Infants
Establish a clinical diagnosis and treatment and long-term follow-up database of preterm infants, and analyze the effects of prenatal factors (including genetic characteristics, maternal diseases, etc.), postnatal diagnosis and…
- Trial name
- NCT05017389
- Testing
- Griffiths development scales
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Children's Medical Center
Hot Water Burns (Scalds)
Health and Environmental Effects of Boiler Management Systems in Social Housing
The purpose of this study is to evaluate the impact of a passive safety measure, namely a reduction in centrally controlled hot tap water temperatures in social housing using a boiler management system, as an effective public…
- Trial name
- NCT00874692
- Testing
- BMS and sterilisation programme
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Maternal Micronutrient Status, Pregnancy
Multiple Micronutrient Versus Iron-Folic Acid Supplementation in Pregnant Women in Indonesia
Micronutrient deficiencies during pregnancy may affect the mother's nutritional status and the baby's growth. This study compared two types of daily supplements for pregnant women: a multiple micronutrient supplement and an iron…
- Conditions
- Maternal Micronutrient Status, Pregnancy, Low Birth Weight, Maternal Anemia
- Trial name
- NCT07725549
- Testing
- Multiple micronutrient supplementation, Iron and Folic Acid Supplementation
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Indonesia Timur University
Sleep Problem, Neurobehavioral Manifestations
NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood
The gut-brain axis plays a crucial role in the regulation and development of psychological and physical processes. The first year of life is a critical period for the development of the gut microbiome, which parallels important…
- Trial name
- NapBiome (NCT06396689)
- Testing
- Synbiotic
- Where
- 2 sites in Switzerland
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Petra Zimmermann
Premature Infants
The Effect of Using Clinical Guidelines on Kangaroo Care on Newborn and Maternal Outcomes
The aim of this study was to determine the effect of the use of clinical guidelines in kangaroo care (KB) practice on neonatal and maternal outcomes in premature infants.
- Trial name
- NCT05807191
- Testing
- Kangaroo care based on kangaroo care guide
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Patent Ductus Arteriosus After Premature Birth
Hemodynamically Important Patent Ductus Arteriosus in Newborns Under 32 Weeks
To define the characteristics of hemodynamically significant PDA by echocardiography, to investigate the systemic effects of the ductus with cerebral and renal Doppler flow studies, and to determine the oxygen consumption in the…
- Trial name
- NCT05686343
- Testing
- Echocardiography, Doppler ultrasonography, Near-infrared spectroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ankara University
Microbial Colonization, Extreme Prematurity
NICU Antibiotics and Outcomes Trial
The goal of the NANO trial is to study the longstanding clinical practice of empirically administering intravenous antibiotics to extremely low birthweight (ELBW) infants in the first days of life.
- Conditions
- Microbial Colonization, Extreme Prematurity, Early-Onset Neonatal Sepsis, Late-Onset Neonatal Sepsis
- Trial name
- NANO (NCT03997266)
- Testing
- Ampicillin, Gentamycin, Normal saline
- Where
- 14 sites in United States
- Volunteers
- 359 people
- Sponsor
- Michael Morowitz