Clinical trials: Bisexuals
Stigma, Social
TENNacity Trial: A Pilot Test of Intersectional CBT Among Young Southern Black and Latino/x GBQ+ Men
This open pilot involves testing the acceptability and feasibility of an intersectional, culturally responsive health intervention by piloting it among young Black and Latino/x gay, bisexual, and queer (GBQ+) men residing in…
- Trial name
- NCT07793357
- Testing
- Adapted ESTEEM intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
HIV
Bridge to Belonging: Peer Led Intervention to Reduce Loneliness and Depression Among Older Gay and Bisexual Men
Older gay and bisexual men living with HIV (OGBMLH) are more likely to experience depression and loneliness, which can lead to negative health outcomes.
- Trial name
- B2B (NCT07762066)
- Testing
- B2B Intervention, Control condition
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Fenway Community Health
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 4
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER4 (NCT05587738)
- Where
- Australia
- Volunteers
- 500 people
- Sponsor
- Monash University
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Hiv, Sexual Health
Parent-focused Intervention to Reduce HIV Risk in Gay and Bisexual Adolescents
Gay and bisexual youth make up 80% of all new HIV infections among adolescents ages 14-19 in the United States, yet interventions to improve sexual health outcomes in these youth are extremely limited.
- Trial name
- NCT05852600
- Testing
- Parents and Adolescents Talking about Healthy Sexuality (PATHS), Lead with Love (LWL)
- Where
- United States
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- George Washington University
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 3
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER3 (NCT05587725)
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Monash University
Cigarette Smoking
Reaching and Treating Lesbian, Gay, Bisexual, and Transgender (LGBT) Cigarette Smokers
Smoking rates are significantly higher among lesbian, gay, bisexual, and transgender (LGBT) populations compared to the general population.
- Trial name
- NCT00634218
- Testing
- Mail-based Self-help plus Internet-based Smoking Treatment, Self-Help Manual plus Telephone counseling, Self-Help Manual
- Where
- United States
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Human Immunodeficiency Virus
Pre-exposure Prophylaxis Implementation in Central-Eastern European Countries
To stem increasing rates of HIV among gay and bisexual men in Central-Eastern Europe, the feasibility, acceptability, and early efficacy of a culturally adapted evidence-based program to introduce pre-exposure prophylaxis (PrEP)…
- Trial name
- NCT05323123
- Testing
- SPARK, HealthMpowerment, PrEP Education
- Where
- 3 sites in United States, Romania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Columbia University
Depressive Symptoms
Resilience Against Depression Disparities (Also Known as Resilience Education to Reduce Depression Disparities)
Depressive symptoms and disorders are among the most common adult health conditions with a lifetime prevalence of 15-20% and are a leading cause of disability /morbidity worldwide.
- Trial name
- RADD (NCT02986126)
- Testing
- Resiliency Class, Resource for Services (RS)
- Where
- 22 sites in United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Bowen Chung, MD, MSHS
HIV, Acquired Immunodeficiency Syndrome
A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk
The intent of the proposed randomized controlled trial is to test the efficacy of a principle-based, transdiagnostic cognitive behavioral therapy (CBT) intervention that addresses the pathways through which minority stress…
- Trial name
- NCT02929069
- Testing
- ESTEEM, CMHT, VCT
- Where
- 2 sites in United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV/AIDS, Sexually Transmitted Infection
The People Like Us Evaluation Study
The study is a pragmatic, randomized controlled trial design to evaluate an online video series developed by a community-based organization in Singapore for gay, bisexual and queer men.
- Conditions
- HIV/AIDS, Sexually Transmitted Infection, Homosexuality, Health Behavior
- Trial name
- NCT04021953
- Testing
- People Like Us Online Video Series Intervention, Sexual Health Pamphlet (Standard of Care)
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Neisseria Gonorrheae Infection
Efficacy Study of 4CMenB (Bexsero®) to Prevent Gonorrhoea Infection in Gay and Bisexual Men
This is a Phase 3, double-blinded, randomised placebo-controlled, multi-centred trial evaluating the efficacy of the four-component meningococcal B vaccine, 4CMenB (Bexsero®), in the prevention of Neisseria gonorrhoeae…
- Trial name
- GoGoVax (NCT04415424)
- Testing
- 4CMenB vaccine
- Where
- 7 sites in Australia
- Volunteers
- 650 people
- Sponsor
- Kirby Institute
HPV
Prevention and Screening for Early Detection of HPV-related Cancers in Gay and Bisexual Men in Tanzania
The long-term objective of the parent study is "to reduce the effects of OPCa through secondary prevention (i.e., early detection, diagnosis and treatment referral)." Consistent with this, this supplement will test HPV-related…
- Trial name
- NCT05616767
- Testing
- Training on self-screening and HPV vaccination administration
- Where
- Tanzania
- Volunteers
- 83 people
- Sponsor
- University of Minnesota
Bacterial Sexually Transmitted Diseases
Doxycycline Intervention for Bacterial STI ChemoprOphylaxis (DISCO)
There is a growing epidemic of the bacterial sexually transmitted infections (STIs) syphilis, chlamydia and gonorrhea worldwide; similarly concerning trends have been noted in Canada, where increases of over 160% have been seen…
- Trial name
- NCT04762134
- Testing
- Doxycycline Hyclate
- Where
- 6 sites in Canada
- Volunteers
- 560 people
- Sponsor
- Jonathan Troy Grennan
Cancer, Hiv
SmartManage Stress Management for HIV+ Cancer Survivors
The purpose of this study is to design and refine a web-based platform developed for managing symptom burden in men who have sex who are HIV+ cancer survivors.
- Conditions
- Cancer, Hiv, Stress
- Trial name
- NCT04544917
- Testing
- SmartManage for HIV+ cancer survivors, Educational Control
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Miami
Smoking Cessation
SmokefreeSGM Español Pilot, Beta Testing a Text-based Smoking Cessation Intervention for Sexual and Gender Minority(SGM) Groups Preferring Spanish Language
The purpose of this study is to test the usability, engagement and acceptability of SmokefreeSGM Español, a culturally and linguistically tailored version of SmokefreeSGM, among Spanish-speaking SGM smokers.
- Trial name
- NCT06487806
- Testing
- SmokefreeSGM
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Infections
Project ICARE: Intervening for Community Awareness, Respect, & Empowerment
This project will test the efficacy of a behavioral intervention to reduce sexual risk for HIV infection among African American Men who Have Sex with Men (MSM).
- Trial name
- NCT00712088
- Testing
- Project ICARE, HCT
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV/AIDS, Substance Use
Understanding and Reducing HIV Risk Behavior and Substance Use Among Self-identified Bisexual Adolescent Men
Young gay, bisexual, and other men who have sex with men (MSM) are disproportionately affected by HIV. Despite this burden, most HIV prevention interventions target adult MSM (most of whom identify as gay) and heterosexual youth…
- Conditions
- HIV/AIDS, Substance Use, Bisexuality
- Trial name
- NCT03409328
- Testing
- HIV and substance use prevention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rosalind Franklin University of Medicine and Science
HIV/AIDS, Methamphetamine Abuse
Depression Intervention Among Gay and Bisexual Men Receiving Treatment for Methamphetamine Use
This study is a single-arm, non-randomized pilot study. Eligible participants are newly enrolled participants in an outpatient methamphetamine treatment program, and study activities will take place contemporaneously with…
- Conditions
- HIV/AIDS, Methamphetamine Abuse, Depression
- Trial name
- NCT03864653
- Testing
- MoodGym
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Friends Research Institute, Inc.
Pre-Exposure Prophylaxis (PrEP), Counseling
Filling Gaps in the HIV Pre-exposure Prophylaxis Cascade Through Counseling
This study s objective is to test the acceptability and feasibility of a guide to facilitate counseling about HIV prevention, focusing on HIV pre-exposure prophylaxis (PrEP).
- Conditions
- Pre-Exposure Prophylaxis (PrEP), Counseling, Sexual and Gender Minorities
- Trial name
- NCT06710171
- Testing
- Counseling, List of resources
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto