Clinical trials: Bispectral Index
Anesthesia
Comparison of Total Intravenous Anesthesia Methods in Spinal Surgery (TIVA)
This study aims to compare the effects of the classical Total Intravenous Anesthesia (TIVA) method and multimodal anesthesia protocols created by adding lidocaine and ketamine infusions on postoperative pain management, opioid…
- Trial name
- TIVA (NCT06781177)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Benign/Malignant Neoplasm, Long Bone Fracture
Correlation of Bispectral Index Score and Total Intravenous Anesthesia (TIVA)
General Anesthesia is usually produced by an intravenous agent and then maintained with a breathing agent till the surgery is completed.
- Trial name
- NCT01618539
- Testing
- propofol
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Rutgers, The State University of New Jersey
General Anaesthesia, Depth of Anaesthesia
Epileptiform EEG Patterns During Induction of General Anaesthesia With Sevoflurane Compared to Those With Propofol
The aim of the study was to assess the influence of volatile induction of general anaesthesia with sevoflurane using two different techniques and intravenous anaesthesia with propofol on the possible presence of epileptiform…
- Conditions
- General Anaesthesia, Depth of Anaesthesia, Intraoperative Awareness, Seizures
- Trial name
- EEG (NCT03209323)
- Testing
- electroencephalography (EEG), bispectral index (BIS), response and state entropy (RE and SE)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Silesia
Artifical Intelligence, Bispectral Index
Bispectral Index in Patients Undergoing Vertebral Surgery Using Artificial Intelligence Programs: A Methodological Study
This study aims to interpret the Bispectral Index (BIS) monitoring method, which we routinely use for monitoring in scoliosis surgery, with artificial intelligence (AI) tools and to determine the accuracy and reliability of AI…
- Conditions
- Artifical Intelligence, Bispectral Index, Spine
- Trial name
- BIS (NCT07650604)
- Testing
- CHATGPT Group, GEMİNİ group, COPİLOT group
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Antalya Health Sciences University
Thoracic Surgery
Does Sedation Depth (as Evaluated by the Bispectral Index) Influence Dynamic Indices of Preload Dependence?
Dynamic indices of preload dependence (such as stroke volume variability -SVV , pulse pressure variability - PPV and plethysmograph variability index - PVI ) are reportedly predictive of the response to vascular filling in…
- Trial name
- BIS2 (NCT02812758)
- Testing
- transthoracic echocardiography
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anesthesia, General
Manual Administration of Propofol-remifentanil Versus Dual Closed-loop Using Bispectral Index as the Control Variable
To compare manual administration of propofol and remifentanil and dual closed-loop using bispectral index as the control variable during anesthesia
- Trial name
- NCT00392158
- Testing
- Closed-loop anesthesia system
- Where
- 6 sites in France
- Volunteers
- 240 people
- Sponsor
- Hopital Foch
Pain, Anesthesia
NoL and BIS Monitoring on Patients Recovery and Safety After Surgery
So far, only vital signs (mostly, blood pressure and heart rate) helped the anesthesiologist to administer hypnotic agents or analgesics.
- Trial name
- CINAAMON (NCT03410485)
- Testing
- BIS index/NoL index, Variation of baseline mean arterial pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Postoperative Delirium (POD), Postoperative Pain
Comparison of Target-Controlled and Manual Total Intravenous Anesthesia in Supratentorial Surgery
This study aims to investigate the effect of target-controlled infusion using the Eleveld pharmacokinetic model compared with manually controlled total intravenous anesthesia on the incidence of postoperative delirium in patients…
- Conditions
- Postoperative Delirium (POD), Postoperative Pain, PONV, Burst Suppression
- Trial name
- NCT07357480
- Testing
- Target Controlled Infusion, Total Intravenous Anesthesia(TIVA)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Istanbul University - Cerrahpasa
Anesthesia
Outcomes of an Intraoperative Bispectral Index Monitor
This pilot study is being conducted to determine whether the intraoperative presence of a Bispectral Index Monitor (BIS), a non-invasive monitor, affects the perioperative and postoperative indices and outcomes.
- Trial name
- NCT03052543
- Testing
- BIS™ Complete 2--Channel Monitor
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
Anesthesia, General, Anesthesia, Intravenous
Evaluation of a Novel Closed-loop Propofol and Remifentanil System Guided by Bispectral Index Compared to a TCI Open-loop System
Closed loop system in intravenous anesthesia is more effective to maintain depth of anesthesia compared with manual system open, it is unclear what driver and variables to achieve this goal be more physiological; in the…
- Trial name
- NCT02492282
- Testing
- Closed-Loop propofol and remifentanil system by Bispectral Index, Open-Loop propofol and remifentanil by Target Controlled Infusion, propofol
- Where
- Colombia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Anesthesia, General, Aged, 70 and Over
Frail Status of Elderly Patients After Repair and Anesthesia Guided by the bispectraL Index
The first aim of this study is to compare two methods of administration of intravenous anesthetics to obtain the same level of depth (bispectral index between 40 and 60): manual or automated and to determine a mid-term (6 months)…
- Trial name
- FRAGIL (NCT02524327)
- Testing
- Toolbox: Automated group, Manual group
- Where
- 4 sites in France
- Volunteers
- 134 people
- Sponsor
- Hopital Foch
Critical Illness
Assessment of Hemodynamic Responses at Adequate Depth of Anesthesia Using Bispectral Index During Rapid Sequence Intubation in the Emergency Department
Rapid sequence intubation (RSI) is the standard approach for emergency airway management in critically ill patients requiring endotracheal intubation.
- Trial name
- NCT07722897
- Testing
- Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Akdeniz University Hospital
Spine Diseases
Awakening in Spine Surgery: A Comparison Between Clinical Signs and Bispectral Index
BIS is one of several equipments used to monitor depth of anesthesia.Some studies found BIS can reduce total propofol dose when being used with target controlled infusion (TCI).The objective is to compare awakening time after…
- Trial name
- NCT02174913
- Testing
- bispectral index, Target controlled infusion of propofol, Fentanyl
- Where
- Thailand
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Sleep Deprivation
Sleep Quality After Stellate-ganglion Block of Patients Undergoing Breast Cancer Operation
Stellate-ganglion block have been done safely for more than 60 years. It has proved to provide survivors of breast cancer with relief from hot flushes and sleep dysfunction with few or no side-effects.
- Trial name
- NCT02651519
- Testing
- 0.25% ropivacaine hydrochloride, saline
- Where
- China
- Volunteers
- 105 people
- Sponsor
- China Medical University, China
Sleep Deprivation
Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery
It has been proved that lithium carbonate can prolong slow wave sleep with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing video assisted thoracic surgery…
- Trial name
- NCT04479566
- Testing
- Lithium Carbonate 250 MG, Calcium Carbonate 500 MG
- Where
- China
- Volunteers
- 51 people
- Sponsor
- China Medical University, China
Anxiety, Pain
Clonidine Versus Midazolam for Premedication
alpha2-agonists like clonidine offer several useful effects that make these drugs an interesting alternative to benzodiazepines for pharmacological premedication.
- Trial name
- NCT00638729
- Testing
- midazolam, clonidine
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital Schleswig-Holstein
Thoracic Surgery
Is the Decrease in the Bispectral Index Correlated With a Decrease in Cardiac Output During the Induction of Anaesthesia?
Monitoring the bispectral index (BIS) as a peri-operative hemodynamic tool appears to be justified by the agreement between various clinical situations in which BIS monitoring appears to be of value: the prognosis in traumatic…
- Trial name
- BIS1 (NCT02812745)
- Testing
- recording of cardiac output, other parameters
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anesthesia Brain Monitoring, Ketamine
Effect of Ketamine Infusion on BIS Values
Aim of this trial is to define if Concentration at the effector site (Ce) of Ketamine, during a continuous infusion and calculated with DOMINO model infusion pump are correlated with Bispectral Index BIS values during general…
- Trial name
- NCT05799729
- Testing
- Ketamine
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Renal Failure Acute Chronic
Bispectral-Electroencephalography (EEG) in First Time Hemodialysis
The severity of minimal dialysis disequilibrium syndrome (DDS) is currently detected and graded clinically using clinical criteria.
- Trial name
- BIS7 (NCT03276273)
- Testing
- recording of Bispectral Index
- Where
- 2 sites in China, Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Esophageal Cancer
Bispectral Index Throughout Esophageal Cancer Operation
The investigators try to conduct a study to assess the impact of changing patients' lateral decubitus position on BIS readings during esophageal cancer operation.
- Trial name
- NCT03397745
- Testing
- BIS
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Samsung Medical Center