Clinical trials: Bispectral Index Monitoring
Bronchoscopy
Narcotrend Versus Bispectral Index Monitoring During Sufentanil-Midazolam Anesthesia for Bronchoscopy
This study was aimed to determine whether narcotrend monitoring was better than bispectral index monitoring during sufentanil-midazolam anesthesia for bronchoscopy under conscious sedation.
- Trial name
- NCT03738137
- Testing
- Narotrend, BIS, Sufentanil
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Pain, Anesthesia
NoL and BIS Monitoring on Patients Recovery and Safety After Surgery
So far, only vital signs (mostly, blood pressure and heart rate) helped the anesthesiologist to administer hypnotic agents or analgesics.
- Trial name
- CINAAMON (NCT03410485)
- Testing
- BIS index/NoL index, Variation of baseline mean arterial pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Colonoscopy
Bispectral Index Monitoring for Sedation in Elective Colonoscopies of Adult Patients: a Randomized Controlled Trial
The primary aim of the study is to determine the rate sedation-induced adverse events, comparing BIS-guided sedation with clinical observation.
- Trial name
- BIS (NCT03453359)
- Testing
- BIS monitor, Ramsay scale
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hospital Galdakao-Usansolo
Surgical Procedure, Unspecified
Sugammadex: Effect on the Awareness Monitoring and Hemodynamics
Sugammadex is used to reverse the neuromuscular blocking effect of steroid neuromuscular blockers. Its cardiovascular effects and effect on brain cortex, if any, may be associated to the reversal of the neuromuscular block.
- Trial name
- NCT01301261
- Testing
- sugammadex, Sugammadex 4 mg/kg, Sugammadex 16mg/kg
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Athens
Anesthesia
Comparative Population Pharmacodynamic Modeling for Sevoflurane Effects Using ADMS and Bispectral Index
The investigators want to compare the performance of anesthetic depth monitoring for sedation (ADMS) to the bispectral index (BIS) as electroencephalographic measures of sevoflurane effect using two combined sigmoidal Emax models…
- Trial name
- NCT03069456
- Testing
- BIS, ADMS
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
Gastric Adenoma, Gastric Cancer
Efficacy of Bispectral Index Monitoring for Midazolam and Meperidine Induced Sedation During Endoscopic Submucosal Dissection
Background: Endoscopic submucosal dissection (ESD) usually requires adequate level of sedation due to lengthy and uncomfortable procedure.
- Trial name
- NCT01157598
- Testing
- bispectral index monitoring
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Samsung Medical Center
Ventilation
Bispectral Index (BIS) on Ventilated Patients in the Prehospital Setting
To evaluate the effectiveness of use of the bispectral index for monitoring of depth of sedation in ventilated patients during their prehospital management by a physician- staffed EMS.
- Trial name
- OHBIS (NCT00919971)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Beaujon Hospital
Total Intravenous Anesthesia, Propofol
Total Intravenous Anesthesia With Remifentanil-propofol Admixture
Background: Application of total intravenous anesthesia (TIVA) may be considered as unpractical when compared with inhalational anesthesia.
- Conditions
- Total Intravenous Anesthesia, Propofol, Remifentanil, Bispectral Index Monitoring
- Trial name
- NCT04394897
- Testing
- Remifentanil-Propofol admixture
- Volunteers
- 96 people
- Sponsor
- Bezmialem Vakif University
Postoperative Cognitive Dysfunction, Delirium, Postoperative
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium
Postoperative cognitive disorders, including postoperative cognitive dysfunction (POCD) and postoperative delirium (POD), are common complications following surgery and anesthesia, particularly in vulnerable patient populations.
- Trial name
- NCT07509372
- Testing
- Perioperative Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 137 people
- Sponsor
- Ankara University
Cardiac Surgery Patients
Bilateral Bispectral Index (BIS)-Monitoring in Cardiac Surgery Patients
The bispectral index (BIS) is derived from a single-channel electroencephalogram (EEG) and provides information on the anaesthetic depth.
- Trial name
- NCT01048775
- Where
- Germany
- Volunteers
- 87 people
- Sponsor
- University Hospital, Bonn
Deep Sedation
Bispectral Index Monitoring To Guide Sedation In The Critical Care Setting
A randomized, control trial to compare the total dose of sedatives use in patients over 65 years admitted to the intensive care unit, guiding sedation by monitoring with BIS® versus monitoring with the exclusive use of sedation…
- Trial name
- BIS65 (NCT02909010)
- Testing
- BIS™ Brain Monitoring System, RASS
- Volunteers
- 150 people
- Sponsor
- Hospital Universitari de Bellvitge
Anesthesia Brain Monitoring, Ketamine
Effect of Ketamine on BIS Values
Aim of this trial is to define if Concentration at the effector site (Ce) of Ketamine, calculated with DOMINO model infusion pump are correlated with Bispectral Index BIS values during general anaesthesia for breast surgery.
- Trial name
- NCT05288764
- Testing
- Bispectral Index
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- University of Padova
Awareness During General Anesthesia
Bispectral Index (BIS) Versus Electronic Alerts in the Prevention of Anesthesia Awareness: the Michigan Awareness Control Study
Awareness during anesthesia is a problem receiving increased attention by patients, clinicians, and the general public. The incidence of intraoperative awareness has been reported to be between 1-2/1000 cases, but recent data…
- Trial name
- MACS (NCT00689091)
- Testing
- Bispectral Index Monitor, Electronic MAC alert
- Where
- United States
- Volunteers
- 22,185 people
- Sponsor
- University of Michigan
Delirium, Postoperative
Bis Monitoring Effect on Delirium Occurrence and Nursing Quality Improvement Recovering From General Anesthesia
①Effects of BIS Index (BIS) monitoring on delirium incidence in Post-anesthesia care unit (PACU) in patients undergoing general anesthesia ②Effects of BIS BIS Index (BIS) monitoring on the quality of nursing care in the…
- Trial name
- NCT06302517
- Testing
- BIS-guided
- Where
- China
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Sedation
Sedation of Advanced Endoscopic Procedure
To evaluate the impacts of target-control infusion (TCI) and bispectral index (BIS) monitoring during advanced endoscopic procedure.
- Trial name
- NCT03172078
- Testing
- advanced endoscopic procedure
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Pulmonary Disease
BIS of Sedation Depth During Flexible Bronchoscopy.
Fentanyl is analgesia medication. There has not pain nerve in the lung. Flexible bronchoscopy(FB) is used in the respiratory medicine. So people will not feel pain in the process of FB.
- Trial name
- BIS (NCT03395093)
- Testing
- Fentanyl, Midazolam, Propofol
- Volunteers
- 500 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
General Anesthesia
Comparison of Two Electroencephalograms (EEG) Monitors in Patients Undergoing General Intravenous Anesthesia
Quantium Medical Company has an ElectroEncephalograph-based (EEG-based) algorithm with two outputs: qCON for unconsciousness and qNOX for anti-nociception.
- Trial name
- Bis-qCON-IV (NCT03753217)
- Testing
- qCON Monitor
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Hopital Foch
General Anesthesia
Multimodal Monitoring During General Anesthesia in ENT Surgery
This study evaluated whether using several monitoring methods together during general anesthesia could improve patient safety and help anesthesiologists adjust medication doses in adults undergoing ear, nose, and throat (ENT)…
- Trial name
- NCT07895836
- Testing
- Multimodal Anesthesia Monitoring (BIS, SPI, TOF), Standard Anesthesia Monitoring
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Barbara Verro
Colonoscopy
Bispectral Index Monitoring During Anesthesiologist - Directed Sedation in Scheduled Colonoscopies
The aim of the study is to establish and identify the level of sedation that is performed in the endoscopy rooms of Galdakao Hospital.
- Trial name
- NCT03461029
- Testing
- BIS monitor
- Where
- Spain
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Hospital Galdakao-Usansolo
Anesthesia
Research on Anesthesia Depth Control Strategy Based on Continuous and Non-invasive Monitoring of Exhaled Breath
This study aims to propose a strategy for controlling the depth of anesthesia based on continuous and non-invasive monitoring of exhaled breath: BIS value during intravenous-inhalation combined anesthesia is predicted according…
- Trial name
- NCT07272044
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine