Clinical trials: Bladder Function, active
Spinal Cord Injuries, Neurogenic Bladder
Pediatric Locomotor Training Bladder Study
Bladder dysfunction is one of the most important factors influencing duration and quality of life in children with spinal cord injury.
- Trial name
- NCT03559036
- Testing
- Locomotor Training
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Intellectual Disability, Healthy Subjects
Bladder and Bowel Functions, Participation and Quality of Life in Children With Intellectual Disabilities
Many neurodevelopmental, psychiatric, and medical disorders are commonly associated with intellectual disability. The presence of neurodevelopmental and psychiatric (NDP) comorbidities has been reported to negatively impact the…
- Trial name
- NCT07059858
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Abant Izzet Baysal University
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Urinary Incontinence, Urge, Urinary Incontinence
TReating Incontinence for Underlying Mental and Physical Health
The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder…
- Conditions
- Urinary Incontinence, Urge, Urinary Incontinence, Overactive Bladder, Incontinence, Urge
- Trial name
- TRIUMPH (NCT05362292)
- Testing
- Tolterodine Tartrate ER, Mirabegron
- Where
- 2 sites in United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pelvic Floor Dysfunctions
Effectiveness of Modern Physical Agents in the Treatment of Pelvic Floor Dysfunctions
This clinical trial aims to determine whether adding modern physical agents (high-intensity laser therapy, magnetotherapy, radial shock wave therapy, kinesiotaping) in conjunction with classical rehabilitation interventions…
- Trial name
- EMPHAT-PFD (NCT06800222)
- Testing
- modern agents rehab, classical rehab
- Where
- Lithuania
- Volunteers
- 250 people
- Sponsor
- Lithuanian University of Health Sciences
Localized Malignant Solid Neoplasm, Anal Cancer
Distance-Based Exercise to Preserve Function and Prevent Disability
This clinical trial studies whether an exercise program can be successfully delivered to patients receiving treatment for cancer through virtual sessions and allow patients to exercise in their own home.
- Conditions
- Localized Malignant Solid Neoplasm, Anal Cancer, Bladder (Urothelial, Transitional Cell) Cancer, Breast Cancer
- Trial name
- DEFEND (NCT07059884)
- Testing
- Exercise intervention, Telemedicine, Aerobic Exercise Intervention
- Where
- 23 sites in United States
- Volunteers
- 104 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Bladder-Bowel Dysfunction, Obesity & Overweight
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel.
- Trial name
- OBE-BBD (NCT07724158)
- Testing
- Target physiotherapy, Exercise support intervention, Usual obesity care
- Where
- Portugal
- Volunteers
- 237 people
- Sponsor
- University of Lisbon
Spinal Cord Injury, Neurogenic Bladder
Electrical Stimulation for Continence After Spinal Cord Injury
This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation. The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel…
- Conditions
- Spinal Cord Injury, Neurogenic Bladder, Incontinence
- Trial name
- NCT02978638
- Testing
- Finetech Vocare Bladder System
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Palo Alto Veterans Institute for Research
Spinal Cord Injuries, Neurogenic Bladder Dysfunction
Functional and Structural Changes in the Central Nervous System Following Spinal Cord Injury
Building on recent improvements, state-of-the-art functional MRI will be applied as an advanced diagnostic tool for the lumbosacral cord in spinal cord injury (SCI) patients to characterize the remaining neuronal activity of the…
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder Dysfunction, Degenerative Cervical Spinal Stenosis
- Trial name
- NCT05681936
- Where
- Switzerland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Acute Leukemia, Multiple Myeloma
INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP)
This is a multicenter, experimental preclinical study conducted on primary samples from patients diagnosed with hematological or solid neoplasms defined as high risk.
- Conditions
- Acute Leukemia, Multiple Myeloma, Squamous Cell Carcinoma, Pleural Mesothelioma
- Trial name
- IT-TCP POS (NCT07403630)
- Testing
- Functional tests, Multi-omics analyses, Cytogenetics/ FISH
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Parkinson Disease (PD)
Pilot Deprescribing of Antimuscarinic Overactive Bladder Medications in Parkinson Disease
This is an unblinded, non-randomized National Institute of Health (NIH) Stage I of Behavioral Intervention Development trial. The investigators will enroll 20 subjects with Parkinson disease (PD) for a series of 20 of N-of-1…
- Trial name
- NCT07627529
- Testing
- Overactive bladder antimuscarinic deprescribing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Corporal Michael J. Crescenz VA Medical Center
Bladder Cancer, Quality of Life
Impacts and Testing of the "Multi-domains Active-living Program" in Operable Non-Muscle Invasive Bladder Cancer Patients
Among bladder cancer, the majority of them (70%) are non-muscle-invasive bladder cancer (NMIBC). The survival time is even longer in NMIBC. Patients with NMIBC receive surgery or transurethral resection of bladder tumor (TURBT).
- Trial name
- NCT05739968
- Testing
- Usual care + oncology case manager (OCM) care, Multi-domains Active-living Program (MAP) with e-health enhanced intervention + usual care + oncology case manager (OCM) care
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder
Effects of Hippotherapy in Children With Autism Spectrum Disorder
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by difficulties in social communication and interaction, as well as impairments in physical function domains such as postural control, balance…
- Trial name
- NCT07739693
- Testing
- Hippotherapy Program, Special Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Spinal Cord Injuries
SPARC Bladder Mapping and Training Study
The investigators propose to determine the electrode configurations that promote functional gains in the storage and voiding phases of lower urinary tract function as a result of activation of spinal circuits with spinal cord…
- Trial name
- NCT03452007
- Testing
- Epidural Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville
Solid Tumor Malignancies, Colorectal Carcinoma
Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
The goal of this clinical trial is to learn if an investigational drug CP-383 works to treat advanced cancer. It will also learn about the safety of CP-383.
- Conditions
- Solid Tumor Malignancies, Colorectal Carcinoma, Small Cell Lung Cancer ( SCLC ), Head and Neck (HNSCC)
- Trial name
- NCT07030257
- Testing
- CP-383
- Where
- 13 sites in United States
- Volunteers
- 150 people
- Sponsor
- Tasca Therapeutics
Cerebral Palsy, Congenital
Effects of Hippotherapy in Children With Cerebral Palsy
Cerebral palsy is a group of permanent disorders affecting movement and posture due to non-progressive disturbances in the developing brain.
- Trial name
- NCT07739680
- Testing
- Hippotherapy Program, Special Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Fenerbahce University
Bladder Pain Syndrome
fMRI for BPS: A Descriptive Study of Findings and Symptoms
The goal of this observational study is to investigate the relationship between functional magnetic resonance imaging (fMRI) findings of the brain and symptom presentation in patients with bladder pain syndrome (BPS).
- Trial name
- NCT06294951
- Testing
- fMRI
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Orthotopic Neobladder
The Supraspinal Control of Lower Urinary Tract Function in Patients With Orthotopic Sigmoid Neobladder.
Orthotopic sigmoid neobladder surgery is one of the ideal urinary diversion methods after radical cystectomy.In recent years, functional imaging studies have revealed brain regions related to urinary system function, but brain…
- Trial name
- NCT05558111
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Bladder Pain Syndrome, Female Sexual Dysfunction
Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is estimated to affect 3.3 to 7.9 million women aged 18 years and older in the United States.
- Trial name
- NCT06729151
- Testing
- Onabotulinum toxin A, Conservative management (dietary and behavioral)
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center