Clinical trials: Bladder Tumors
Bladder Cancer
High-Dose Multivitamins Compared to a Placebo in Preventing the Recurrence of Cancer in Patients With Early Stage Bladder Cancer
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of high-dose multivitamins may be an effective way to prevent the recurrence of early stage bladder…
- Trial name
- NCT00003623
- Testing
- multivitamin
- Where
- 17 sites in United States, Canada
- Volunteers
- 21 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Prostate Cancer, Community-based Screening
Establishment and Promotion of an AI-Based Early Warning System for Prostate and Bladder Cancer Screening in the Male Community Population of Beijing
Prostate cancer is one of the most common malignancies in the male genitourinary system, and it is also the cancer with the fastest-growing incidence and mortality rates among men in China.
- Trial name
- NCT07319923
- Testing
- No intervention
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Urinary Bladder Cancer
PURO Panitumumab in Combination With Gemcitabine/Cisplatin in Advanced Urothelial Cancer
The primary objective of the study is to assess the efficacy of the combination consisting of gemcitabine/cisplatin and panitumumab in patients with urothelial carcinoma and wild-type HRAS (non-mutated status).
- Trial name
- PURO (NCT01374789)
- Testing
- GemCis + Panitumumab, GemCis
- Where
- 20 sites in Germany
- Volunteers
- 2 people
- Sponsor
- WiSP Wissenschaftlicher Service Pharma GmbH
Prostate Cancer, Bladder Cancer
Assessing Financial Toxicity Using the PROFFIT Questionnaire in Patients Treated With Mini-invasive Approach for Urological Malignancies.
Patients previously treated with robotic surgery for urological cancers such as prostate, bladder and kidney cancer will be enrolled, in particular patients operated in the last twelve months will be included after signing the…
- Conditions
- Prostate Cancer, Bladder Cancer, Kidney Cancer
- Trial name
- NCT06955910
- Testing
- questionnaires
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Intermediate or High-risk Bladder Cancer
Hexvix Photodynamic Therapy in Patients With Bladder Cancer
The purpose of the study is to investigate the safety and feasibility of Hexaminolevulinate based photodynamic therapy in patients with intermediate or high-risk transitional cell carcinoma of the bladder.
- Trial name
- NCT01303991
- Testing
- Hexvix PDT with Karl Storz T-Light
- Volunteers
- 17 people
- Sponsor
- Photocure
Bladder Cancer
Neoadjuvant Chemotherapy in Non Muscle Invasive T1b Bladder Cancer
The aim of our study is to evaluate the benefit of NAC in T1b NMIBC .
- Trial name
- NCT04245618
- Testing
- neoadjuvant chemotherapy ( cisplatin - gemcitabine)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Bladder Cancer
CD155 in Bladder Cancer
This research is designed to investigate the prognostic and predictive value of CD155 in muscle invasive bladder cancer.
- Trial name
- NCT03789682
- Testing
- Adjuvant chemotherapy
- Where
- China
- Volunteers
- 151 people
- Sponsor
- Fudan University
Cervical Carcinoma, Endometrial Carcinoma
Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy
This clinical trial studies how well and how easy it is to use a device called Flyte in improving problems with bladder control (urinary incontinence) among endometrial and cervical cancer survivors who have undergone radiation…
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Overactive Bladder, Voiding Disorders
- Trial name
- NCT07662824
- Testing
- Educational Intervention, Interview, Flyte Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Mayo Clinic
Bladder Cancer
Relationship Between Methods of Bladder Tumor Extraction and Local Recurrence Rate
According to clinical guidelines, endoscopic surgery (mono- or bipolar TURBT, laser resection, en bloc resection) is a standard treatment option for patients with primary non-muscle invasive bladder cancer (NMIBC) (excluding…
- Trial name
- NCT04750590
- Testing
- en bloc resection, morcellation, piecemeal resection, tissue removal by loop
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Catheter Site Discomfort, Complications
Sevoflurane Versus Desflurane for Catheter-related Bladder Discomfort
We want to evaluate the efficacy of the sevoflurane and desflurane for the prevention of catheter-related bladder discomfort.
- Conditions
- Catheter Site Discomfort, Complications, Anesthesia, Urinary Bladder Neoplasms
- Trial name
- NCT02096224
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Cholangiocarcinoma, Gall Bladder Carcinoma
Adjuvant Chemotherapy for Biliary Tract Cancer After Curative Resection
This prospective, open-Label, comparative, randomized, controlled phase III trial was designed to compare the clinical performance of gemcitabine with capecitabine vs.
- Trial name
- AdBTC-1 (NCT03779035)
- Testing
- Gemcitabine, Capecitabine
- Where
- China
- Volunteers
- 460 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Explore Whether lncRNA-ElNAT1 in Urine Exosomes Can be Used as a New Target for Preoperative Diagnosis of Lymph Node Metastasis
A Prospective, Multicenter Cohort Study of Urinary Exosome lncRNAs for Preoperative Diagnosis of Lymphatic Metastasis in Patients With Bladder Cancer
Bladder cancer is one of the most frequent malignant tumors of the urinary system in China, seriously threatening the life safety of patients.
- Trial name
- NCT05270174
- Testing
- no intervention
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Bladder Cancer
Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)
The purpose of this study was to evaluate the 2-Year Recurrence Rate of bladder cancer in randomized patients with tumor histology Ta, G1-G2 who received TransUrethral Resection of Bladder Tumor (TURBT) plus apaziquone versus…
- Trial name
- NCT00461591
- Testing
- Apaziquone, TURBT
- Where
- 74 sites in United States
- Volunteers
- 802 people
- Sponsor
- Spectrum Pharmaceuticals, Inc
Urinary Bladder Cancer, Upper Tract Urothelial Cancer
SeqUential GeMcitabine and MITomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma
This Phase II clinical trial, titled "A Phase II Trial of Sequential Gemcitabine and Mitomycin Treatment for Favorable High-Risk Upper Urinary Tract Urothelial Carcinoma (SUMMIT)," aims to evaluate the safety and effectiveness of…
- Conditions
- Urinary Bladder Cancer, Upper Tract Urothelial Cancer, Urothelial Cancer
- Trial name
- NCT06822010
- Testing
- Sequential Gemcitabine and Jelmyto Treatment (Gem/Jel)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Rutgers, The State University of New Jersey
Bladder Cancer
Suramin in Treating Patients With Recurrent Bladder Cancer
RATIONALE: Suramin may stop the growth of bladder cancer by stopping blood flow to the tumor. PURPOSE: Phase I trial to study the effectiveness of suramin in treating patients who have recurrent bladder cancer.
- Trial name
- NCT00006476
- Testing
- suramin, conventional surgery
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Cancer Research UK
Lymphocele After Surgical Procedure
MICHL-trial: Impact of Peritoneal Bladder Flap in RARP Patients on Lymphoceles
A two-armed prospective randomised, controlled, single-centre trial on 1080 patients with prostate cancer who underwent robot-assisted radical prostatectomy with bilateral pelvic lymph node dissection was carried out.
- Trial name
- NCT06284135
- Testing
- Michl-stitch
- Where
- Germany
- Volunteers
- 1,080 people
- Sponsor
- Martini-Klinik am UKE GmbH
Bladder Cancer
Impact of Time to Re-staging Transurethral Resection on Recurrence and Progression Rates
Purpose To investigate the significance of time to re-staging transurethral resection (re-TUR) on recurrence and progression rates in patient with high-risk non-muscle-invasive bladder cancer.
- Trial name
- NCT04768894
- Testing
- Second transurehral resection of bladder tumour
- Volunteers
- 109 people
- Sponsor
- Saglik Bilimleri Universitesi
Bladder Cancer
Perioperative Pembrolizumab (MK-3475) Plus Neoadjuvant Chemotherapy Versus Perioperative Placebo Plus Neoadjuvant Chemotherapy for Cisplatin-eligible Muscle-invasive Bladder Cancer (MIBC) (MK-3475-866/KEYNOTE-866)
A global study to evaluate peri-operative pembrolizumab with chemotherapy versus placebo to pembrolizumab plus chemotherapy in cisplatin eligible patients.
- Trial name
- KEYNOTE-866 (NCT03924856)
- Testing
- Pembrolizumab, Gemcitabine, Cisplatin
- Where
- 175 sites in United States, Australia and 20 more
- Volunteers
- 907 people
- Sponsor
- Merck Sharp & Dohme LLC
Bladder Cancer, Non Muscle Invasive Bladder Cancer
Predictors of Residual Tumor at Second Transurethral Resection for pT1 Non-muscle Invasive Bladder Cancer
The START study is a multicentre retrospective project. The aim is to identify clinico-pathological predictors of residual tumor at time of second transurethral resection of bladder tumor (re-TURBt) and to identify well-selected…
- Trial name
- START (NCT06205277)
- Testing
- Second TURBt
- Where
- Italy
- Volunteers
- 1,300 people
- Sponsor
- University of Trieste
Bladder Cancer, Urothelial Carcinoma Bladder
Evaluating Bladder CARE™, a New Non-Invasive Urine Test, for Bladder Cancer Detection in Inconclusive Cases
The goal of this observational study is to learn about the performance of the Bladder CARE™ Assay in patients suspected of having bladder cancer with atypical cytology or equivocal cystoscopy results.
- Trial name
- NCT06870253
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Pangea Laboratory LLC
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