Clinical trials: Bleed Intracranial
Stroke Hemorrhagic, Depression
Poststroke Depression in Hemorrhagic Stroke
A double-blinded placebo-controlled randomized trial to evaluate the effect of preventative treatment of depression in survivors of aneurysmal subarachnoid hemorrhage (aSAH), a type of stroke.
- Trial name
- NCT03826875
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Washington
Aneurysmal Subarachnoid Hemorrhage, Delayed Neurological Deficit
Effects of Donepezil on Regional Cerebral Blood Flow Following Aneurysmal Subarachnoid Haemorrhage
Introduction Aneurysmal subarachnoid hemorrhage (aSAH) is bleeding around the under surface of the brain caused by rupture of an aneurysm arising from a blood vessel.
- Conditions
- Aneurysmal Subarachnoid Hemorrhage, Delayed Neurological Deficit, Delayed Cerebral Ischemia, Vasospasm
- Trial name
- DASH (NCT02222727)
- Testing
- Donepezil
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- St George's, University of London
Intracranial Hemorrhage, Traumatic, Embolism and Thrombosis
Traumatic Intracranial Hemorrhage in Users of Oral Antithrombotic Drugs
Oral antithrombotic medications (OAM) are used for the prevention and treatment of thrombotic disorders. Among hemorrhagic complications of OAMs, intracranial hemorrhage (ICH) may have particularly devastating consequences with…
- Conditions
- Intracranial Hemorrhage, Traumatic, Embolism and Thrombosis, Hematoma, Subdural, Intracranial
- Trial name
- NCT02996851
- Volunteers
- 6,279 people
- Sponsor
- St. Olavs Hospital
Cerebral Hemorrhage
Restart Anticoagulation in Patients With Spontaneous Intracerebral Hemorrhage and Mechanical Heart Valves
The investigators retrospectively reviewed the electronic medical records of the patients with spontaneous cerebral hemorrhage and mechanical valves from 2015 to 2020 in the second affiliated hospital of Zhejiang university…
- Trial name
- NCT04450446
- Testing
- Low molecular weight heparin
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Subarachnoid Hemorrhage, Aneurysmal
The Role of Deep Cerebral Vein Variation in Patients With Angiographic Negative Subarachnoid Hemorrhage
The incidence of Rosenthal basilar vein (BVR) variants (deep venous drainage variants) was relatively increased in patients with AN-SAH compared with patients with aneurysms.
- Trial name
- NCT04941846
- Testing
- nimodipine and euvolemia
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures
Dutch Intracerebral Hemorrhage Surgery Trial
Background: Intracerebral hemorrhage (ICH) accounts for 16-19% of all strokes in Western Europe and contributes profoundly to mortality and disability.
- Conditions
- Intracerebral Hemorrhage, Minimally Invasive Surgical Procedures, Endoscopic Surgical Procedures
- Trial name
- DIST (NCT05460793)
- Testing
- Minimally invasive endoscopy-guided surgery
- Where
- 11 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Radboud University Medical Center
Ischemic Stroke, Intracranial Hemorrhages
Registry of Patients With Remote Posterior cErebral Hemorrhage Following Reperfusion Treatment in Ischemic Stroke
Introduction Remote cerebral hemorrhage following reperfusion treatment in ischemic stroke is rare (1.3-3.7% of all treated strokes) and is associated with worse functional and vital prognosis.
- Conditions
- Ischemic Stroke, Intracranial Hemorrhages, Hemorrhagic Transformation Stroke
- Trial name
- HEROES-CAT (NCT05871528)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Premature Birth, Extremely Low Birth Weight
DCS Study in Extremely Premature Newborns
The researchers are attempting to improve the cerebral monitoring of extremely low gestational age (ELGA) infants, such that in the future, real-time monitoring will be possible, to aid clinicians in management of these infants.
- Conditions
- Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
- Trial name
- NCT04367181
- Testing
- Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Maria Angela Franceschini
ARDS, Human, Extracorporeal Membrane Oxygenation Complication
Predictors of Intracranial Hemorrhage in ARDS Patients on ECMO
Intracranial hemorrhage is is a rare, but critical incident in patients with acute lung failure undergoing ECMO therapy. Predictors of intracranial hemorrhage are yet to be defined to identify patients at (high) risk.
- Trial name
- NCT04142775
- Testing
- complication versus no complication
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Charite University, Berlin, Germany
Intra Cerebral Hemorrhage
Validation of the ICH Score for the Prediction of 12-month Functional Outcome in Patients With Primary Intracerebral Hemorrhage
The goal of this observational study is to analyze the validity of the intracerebral hemorrhage (ICH) Score and a new modified ICH score for the prediction of 12-month functional outcome in patients with primary ICH.
- Trial name
- NCT05808777
- Testing
- Phone interview
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Chronic Subdural Hematoma
A Study to Evaluate Endoscope-assisted, Minimally-invasive Cortical Access System for Chronic Subdural Evacuation
The purpose of this study is to evaluate a less-invasive alternative to the currently available method of removing aging blood in the subdural space.
- Trial name
- NCT04502745
- Testing
- Minimally Invasive Cortical Access System (MICAS)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
InTracranial Haemorrhage
FAITH - Factor XA Inhibitor-Related InTracranial Haemorrhage
FAITH study is a multicentre retrospective analysis study that aims to understand the burden of ICH related to FXa inhibitors and the current treatment approaches in country/countries where specific reversal agents are not…
- Trial name
- FAITH (NCT06420011)
- Where
- 10 sites in Argentina, Brazil and 5 more
- Volunteers
- 123 people
- Sponsor
- AstraZeneca
Stroke
Glial Fibrillary Acidic Protein Testing and Handheld Near Infrared Spectroscopy Technology CEREBO in India.
CEREBO is an ICMR award winning point-of-care (POC) adjunct CT scanning device for detecting brain hematomas in patients with head injury.
- Trial name
- NCT07844109
- Testing
- GFAP/D-Dimer Point-of-Care Testing & CEREBO Near-Infrared Spectroscopy (NIRS), CT Head
- Where
- 2 sites in India
- Volunteers
- 232 people
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Traumatic Brain Injury, Intracranial Hemorrhages
Usability Study of CEREBO® - A Novel Non-invasive Intracranial Bleed Detector
Traumatic Brain Injury (TBI) is the leading cause of death and disability across the globe. Time from injury to treatment is the most critical factor that determines the patient's recovery.
- Trial name
- NCT05340114
- Testing
- CEREBO®
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Bioscan Research Pvt. Ltd.
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
CVA (Cerebrovascular Accident), Cerebral Hemorrhage
Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
The purpose of the study is to determine whether lowering high blood pressure levels after the start of a stroke caused by bleeding in the brain (intracerebral haemorrhage) will reduce the chances of a person dying or surviving…
- Conditions
- CVA (Cerebrovascular Accident), Cerebral Hemorrhage, Intracranial Hemorrhages
- Trial name
- NCT00226096
- Testing
- Labetalol Hydrochloride, Metoprolol tartrate, Hydralazine Hydrochloride
- Where
- 20 sites in Australia, China and 1 more
- Volunteers
- 404 people
- Sponsor
- The George Institute
Intracerebral Haemorrhage, Intracerebral Hemorrhage
Timing and Outcomes of Recovery After intraCerebral Hemorrhage
The TORCH registry is a prospective, observational cohort study, which will collect detailed, longitudinal data on the clinical characteristics, treatment modalities, and outcomes of patients with ICH.
- Trial name
- TORCH (NCT07166146)
- Testing
- Surgical interventions
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Hemorrhage
Effects of Augmented Renal Clearance on Pharmacokinetic and Pharmacodynamic Properties of Levetiracetam in Subarachnoid Hemorrhage
This study evaluates the pharmacokinetic profile of levetiracetam in critically ill patients who have suffered a subarachnoid hemorrhage.
- Trial name
- NCT02866877
- Testing
- Pharmacokinetic modeling
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver
Fall, Head Injury Trauma
The Emergency Department Falls Study
This is a pilot study to evaluate clinical predictors of intracranial bleeding in elderly patients who present to the emergency department (ED) after a fall.
- Conditions
- Fall, Head Injury Trauma, Intracranial Hemorrhages
- Trial name
- FALLS (NCT03870867)
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 1,753 people
- Sponsor
- Hamilton Health Sciences Corporation
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia
Swiss SOS MoCA - DCI Study
The primary objective of this multicenter observational study is to determine the effect size of the relationship between DCI and neuropsychological impairment 14-28 days and 3 months after aSAH.
- Conditions
- Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, Stroke, Complication
- Trial name
- NCT03032471
- Testing
- There is no intervention for this study. Patients are allocated to the study groups based on whether or not DCI occurs.
- Where
- 6 sites in Switzerland
- Volunteers
- 128 people
- Sponsor
- Swiss SOS Study Group
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