Clinical trials: Bleed Intracranial
Subarachnoid Hemorrhage, Aneurysmal, Headache
Neuroinflammatory Response and Headache Control in Patients After Subarachnoid Hemorrhage
The purpose of this study is to determine the relationship between the Neuroinflammatory response and headache pain after subarachnoid hemorrhage.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Headache, Subarachnoid Hemorrhage
- Trial name
- HASH4-CSF (NCT03604276)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MaineHealth
Intracranial Aneurysm
Guided Antiplatelet Therapy in Interventional Treatment of Intracranial Aneurysms
The use of intracranial stents expands the possibilities for endovascular treatment of intracranial aneurysms and improves the success rate. However, it also increases the risk of ischemic complications in patients.
- Trial name
- GATITIA (NCT05825391)
- Testing
- Adjustment of Antiplatelet Drugs
- Where
- 2 sites in China
- Volunteers
- 590 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Stroke (in Patients With Atrial Fibrillation)
Thrombolysis in Factor Xa-inhibitors Trial
This study looks at whether stroke patients who take FXa inhibitors (a type of blood thinner) can safely receive clot-busting treatment (IVT).
- Conditions
- Stroke, Stroke (in Patients With Atrial Fibrillation), Ischemic Stroke, Acute Ischemic Stroke
- Trial name
- SIFT (NCT06878066)
- Testing
- thrombolysis therapy
- Where
- 21 sites in Denmark, Norway and 1 more
- Volunteers
- 300 people
- Sponsor
- Guri Hagberg
Cerebral Amyloid Angiopathy, Intracranial Hemorrhages
Application of Amyloid PET in Cerebral Amyloid Angiopathy
In this project, we will try to enhance the diagnostic potentials of amyloid PET in CAA by combination of dynamic amyloid PET with MRI SWI and MR perfusion images.
- Conditions
- Cerebral Amyloid Angiopathy, Intracranial Hemorrhages, Alzheimer Disease
- Trial name
- CAA (NCT03542656)
- Testing
- amyloid PET
- Where
- Taiwan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Head Trauma
Monitoring of Intracranial Hemorrhage in Non-severe Head Trauma Patients Hospitalized in the UHCD
The non-neurosurgical management of post-traumatic cerebral hemorrhagic lesions is currently poorly codified. It consists of neurological monitoring for 24 to 48 hours, and the performance of an almost systematic brain scan.
- Trial name
- Head-Trauma (NCT06173427)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Strasbourg, France
Craniocerebral Trauma, Intracranial Aneurysm
Hypovitaminosis D in Neurocritical Patients
Vitamin D has been shown to impact prognosis in a variety of retrospective and randomized clinical trials within an intensive care unit (ICU) environment.
- Conditions
- Craniocerebral Trauma, Intracranial Aneurysm, Brain Neoplasms, Spinal Cord Injuries
- Trial name
- NCT02881957
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- University of Utah
Intracerebral Haemorrhage
Efficacy and Safety of Mirabegron in Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) accounts for 10-15% of all strokes without effective pharmacological treatment. Inflammation following ICH contributes to barrier disruption and peri-hematoma edema, leading to deterioration of…
- Trial name
- NCT05369351
- Testing
- Standard treatment+mirabegron, Standard treatment
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Tianjin Medical University General Hospital
Acute Coronary Syndrome, Venous Thrombosis
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Practice (Sweden)
This prospective cohort study will provide information about: Characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed standard of care for the first…
- Conditions
- Acute Coronary Syndrome, Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation
- Trial name
- NCT02468102
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Standard of care drugs
- Where
- Sweden
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Chronic Subdural Hematoma
A Study to Evaluate Endoscope-assisted, Minimally-invasive Cortical Access System for Chronic Subdural Evacuation
The purpose of this study is to evaluate a less-invasive alternative to the currently available method of removing aging blood in the subdural space.
- Trial name
- NCT04502745
- Testing
- Minimally Invasive Cortical Access System (MICAS)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Cognitive Impairment, Intracerebral Hemorrhage
Fufang Congrong Yizhi Capsules (FCYC) of Cognitive Impairment After Intracerebral Hemorrhage
This is a randomized, controlled clinical study conducted across multiple centers. The neurosurgical robot can be used to treat patients with acute intracerebral hemorrhage (ICH).
- Trial name
- NCT06673602
- Testing
- FCYC+Conventional treatment, conventional treatment
- Where
- 6 sites in China
- Volunteers
- 200 people
- Sponsor
- Qinhuangdao Hospital of Traditional Chinese Medicine
Intracranial Hemorrhage
INVEST-REGISTRY: Minimally Invasive Endoscopic Surgical Treatment With Apollo/Artemis in Patients With Brain Hemorrhage
Objective: The primary objective of this multicenter prospective registry is to provide additional safety, technical outcomes and clinical outcomes data for minimally invasive endoscopic surgery (MIES) with Apollo or Artemis for…
- Trial name
- NCT02661672
- Testing
- Apollo Device, Artemis Device
- Where
- 7 sites in United States
- Volunteers
- 38 people
- Sponsor
- J. Mocco
Subarachnoid Hemorrhage
Impact of Ultra-Early Intracranial Aneurysm Treatment in SAH
This is the first prospective study in Hong Kong that recruit patients with poor neurological status after intracranial aneurysm rupture in all seven public neurosurgical services in Hong Kong.
- Trial name
- UEAT (NCT03894202)
- Where
- China
- Volunteers
- 293 people
- Sponsor
- Chinese University of Hong Kong
Subdural Hematoma, Non-acute
Managing Non-acute Subdural Hematoma Using Liquid Materials：a Chinese Randomized Trial of MMA Treatment
MAGIC-MT study is multi-center, prospective, randomized (1:1) controlled trial designed to show that additional MMA embolization with Onyx in patients with non-acute symptomatic subdural hematoma(SDH) results in reduced hematoma…
- Trial name
- MAGIC-MT (NCT04700345)
- Testing
- Onyx, Burr-hole, Medical Management
- Where
- China
- Volunteers
- 722 people
- Sponsor
- Huashan Hospital
Acquired Bleeding Disorder, Intracerebral Haemorrhage
Safety and Preliminary Efficacy of Activated Recombinant Human Factor VII for Preventing Early Hematoma Growth in Acute Intracerebral Haemorrhage
This trial is conducted in the United States of America (USA). The aim of this trial is to evaluate the safety and preliminary efficacy of activated recombinant human factor VII (NovoSeven®) for preventing early hematoma growth…
- Trial name
- NCT01563445
- Testing
- activated recombinant human factor VII
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Novo Nordisk A/S
Subarachnoid Hemorrhage
Intraventricular Fibrinolysis for Aneurysmal Subarachnoid Hemorrhage.
Aneurysmal subarachnoid hemorrhage (SAH) is a devastating form of stroke, with delayed cerebral ischemia (DCI) as a major complication.
- Trial name
- FIVHeMA (NCT03187405)
- Testing
- EVD + IVF with Alteplase
- Where
- France
- Volunteers
- 81 people
- Sponsor
- University Hospital, Caen
Intracerebral Hemorrhage
Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH)
The purpose of this study is to find risk factors for hemorrhagic stroke, specifically intracerebral hemorrhage (ICH), among Caucasians, African Americans, and Hispanics.
- Trial name
- ERICH (NCT01202864)
- Where
- 15 sites in United States
- Volunteers
- 6,000 people
- Sponsor
- University of Cincinnati
Subarachnoid Hemorrhage
Neuroinflammation and Bispectral Index After Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is associated with a high mortality and frequently leads to severe disability in survivors caused by cerebral vasospasm and infarction.
- Trial name
- NCT01516671
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Stroke, Cerebrovascular Diseases
An EHR-based Platform To Facilitate Outcomes and Research Methods in Cerebrovascular Diseases
In this protocol, the investigators present methods and preliminary results from the PLATFORM-CVD Study, an EHR-based multicenter cohort.
- Conditions
- Stroke, Cerebrovascular Diseases, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- PLATFORM-CVD (NCT04775836)
- Where
- China
- Volunteers
- 300,000 people
- Sponsor
- Ministry of Science and Technology of the People´s Republic of China
Subdural Hematoma, Atrial Fibrillation
Anticoagulation Therapy Timing in Atrial Fibrillation After Acute and Chronic Subdural Hematoma
Subdural hematoma (SDH) is a common disorder that typically results from head trauma and has increased in prevalence in recent decades.
- Trial name
- ATTAACH (NCT05472766)
- Testing
- Direct Acting Oral Anticoagulant starting at Day 30, Direct Acting Oral Anticoagulant starting at Day 90
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Sunnybrook Health Sciences Centre
Intracerebral Hemorrhage
Prospective Cohort Study of Intracerebral Hemorrhage
The investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult…
- Trial name
- POSTER (NCT04707105)
- Where
- China
- Volunteers
- 856 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
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