Clinical trials: Bloating
Poor Energy Levels, Poor Metabolism
A Clinical Trial to Evaluate the Effects of a Supplement on Supporting Signs of a Healthy Metabolism
This study evaluates the effects of Love Wellness Energize, a dietary supplement, on supporting signs of a healthy metabolism in women aged 25-45 who report poor energy levels, perception of poor metabolism, difficulty with…
- Conditions
- Poor Energy Levels, Poor Metabolism, Difficulty With Weight Management, Bloating
- Trial name
- NCT07765407
- Testing
- Love Wellness Energize
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Functional Dyspepsia
Trial of Itopride 150mg Once a Day Versus Itopride 50 mg Thrice a Day; in Patients With Functional Dyspepsia
The study is conducted in patients with functional dyspepsia or chronic gastritis. The purpose of this study is to: assess whether the dose of Itopride Hydrochloride 150 mg extended release tablets, taken once daily has a similar…
- Trial name
- NCT06217393
- Testing
- Itopride Hydrochloride 150 mg extended release tablets, Itopride Hydrochloride 50 mg film coated tablets
- Where
- 19 sites in Armenia, Malaysia and 3 more
- Volunteers
- 564 people
- Sponsor
- Abbott
Digestive Disease, Gut Health
Impact of B. Adolescentis iVS-1 Probiotic on Gastrointestinal Outcomes
The study team is conducting a consumer-driven, decentralized clinical research study to assess the impact of the consumer-grade probiotic supplement, iVS-1, on adults with moderate to severe gastrointestinal discomfort.
- Trial name
- NCT07408518
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Synbiotic Health
Indigestion, Nausea
YM443 in Subjects With Functional Dyspepsia
The primary objective of this study will be to characterize the dose response profile of YM443 in subjects with functional dyspepsia (FD) to enable the selection of doses for the Phase 3 clinical trial.
- Trial name
- NCT00102310
- Testing
- YM443
- Where
- 59 sites in United States
- Volunteers
- 416 people
- Sponsor
- Astellas Pharma Inc
Gut Health
Effectiveness of a Butyrate Formulation and Butyrate + Polyphenol Formulation on Gut Health, Permeability and Associated Symptoms
The purpose of this study is the assess the effectiveness and safety of a Butyrate formulation and a Butyrate + Polyphenol formulation on gut health, permeability and associated symptoms
- Trial name
- NCT06419231
- Testing
- Butyrate Formulation, Butyrate + Polyphenol Formulation
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Supplement Formulators, Inc.
Flatulence, Bloating
Efficacy of Probiotics on Excessive Gas Accumulation
Efficacy of probiotics on excessive gas accumulation
- Trial name
- NCT03134469
- Testing
- Probiotic supplement
- Where
- 2 sites in Sweden
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Probi AB
Postprandial Abdominal Distension, Bloating
A Study to Evaluate Acute and Short-term Efficacy of Digest Gold on Postprandial Abdominal Distension and Subjective Bloating in Healthy Adults
The goal of this clinical trial is to investigate the acute and short-term efficacy of Digest Gold on postprandial abdominal distension and subjective bloating in healthy adults.
- Trial name
- NCT07830992
- Testing
- Digest Gold
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Enzymedica
Gastrointestinal, Microbiota Balance
The Effects of a Postbiotic Supplement on Biomarkers of Gut Health
This study is a randomized, double-blind, two-arm, placebo-controlled trial of N=80 (40/arm) apparently healthy men and women between 18 and 65 years old to be recruited at a single investigational center in Northeast Ohio (i.e.…
- Conditions
- Gastrointestinal, Microbiota Balance, Microbiota, Cortisol
- Trial name
- NCT07527286
- Testing
- Postbiotic
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Verb Biotics LLC
Dyspepsia
Long-term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia
Itopride is a compound already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia.
- Trial name
- NCT00110968
- Testing
- Itopride hydrochloride
- Volunteers
- 300 people
- Sponsor
- Forest Laboratories
Functional Bloating
Effect of Bacillus Subtilis ATCC 122264 Supplementation on Gas Symptoms and Quality of Life in Participants With Functional Bloating
A randomized, double blind, placebo-controlled, 2-arm parallel study to evaluate the efficacy of Bacillus subtillis in providing relief and improving quality of life in participants suffering from functional abdominal…
- Trial name
- NCT06308146
- Testing
- Bacillus subtilis ATCC 122264
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kerry Group P.L.C
Irritable Bowel Syndrome With Diarrhea
Mesalamine Granules for Irritable Bowel Syndrome (IBS) With Diarrhea
The purpose of this study is to determine the daily dose of mesalamine granules that will provide adequate relief from symptoms of IBS with diarrhea.
- Trial name
- NCT01177410
- Testing
- Mesalamine Granules 750 mg, Mesalamine Granules 1500 mg
- Where
- 20 sites in United States
- Volunteers
- 148 people
- Sponsor
- Bausch Health Americas, Inc.
Digestive Health, Digestion
A Single Group Study to Evaluate the Efficacy of Bye Bye Bloat Capsules in Relieving Bloating and Promoting Healthy Digestion.
This virtual single-group study aims to evaluate the efficacy of Bye Bye Bloat Capsules in relieving hormonal and food-related bloating and promoting healthy digestion.
- Trial name
- NCT06516744
- Testing
- Bye Bye Bloat Capsules
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Gut Health, Bowel Movements
A Clinical Trial to Evaluate the Effect of ConcenTrace Trace Mineral Drops on Gut Health
This is a virtual single-arm trial that will last 12 weeks. Participants will take the drops daily and complete questionnaires at Baseline, Week 4, Week 8, and Week 12.
- Conditions
- Gut Health, Bowel Movements, Constipation, Bloating
- Trial name
- NCT06122571
- Testing
- ConcenTrace
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trace Minerals
Women With IBS-C
A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
The purpose of this study is to evaluate the effect of a commercially available fermented dairy product containing probiotics (4 weeks, twice a day) on abdominal distension in IBS patients with constipation (IBS-C).
- Trial name
- NCT01097993
- Testing
- 1-fermented dairy product, 2- milk-based non-fermented dairy product (control product)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Irritable Bowel Syndrome
Pain Relief In Irritable Bowel Syndrome
The purpose of this study is to determine whether Proklama is effective in significative reduction of pain, other symptoms IBS's related, and improves quality of life concerning IBS disease.
- Trial name
- PRITON (NCT02573844)
- Testing
- Proklama
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Geophyt S.r.l.s.
Small Intestinal Bacterial Overgrowth, SIBO
The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Related Gastrointestinal Symptoms
The goal of this study is to test the effect of a probiotic formulation on gastrointestinal symptoms, gut and small intestine microbiota in participants suffering from small intestinal bacterial overgrowth (SIBO).
- Trial name
- NCT06317441
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 105 people
- Sponsor
- Nimble Science Ltd.
Functional Bowel Disorder
Efficacy and Safety of Mebeverine + Simethicone in Patients With Functional Bowel Disorders
The parallel three-group study of efficacy and safety was planned to investigate the reduction in abdominal pain and bloating during treatment with the fixed-dose combination of Mebeverine + Simethicone versus Duspatalin® and…
- Trial name
- NCT05175131
- Testing
- Mebeverine+Simethicone, Mebeverine, Simethicone
- Where
- Russia
- Volunteers
- 465 people
- Sponsor
- Abbott
Dyspepsia
Long-Term Safety and Efficacy of Itopride Hydrochloride (HCl) in Patients Suffering From Functional Dyspepsia
Itopride is a compound already marketed in Japan and in some countries of Eastern Europe under the name of Ganaton. It is used to treat symptoms of functional dyspepsia.
- Trial name
- NCT00112203
- Testing
- Itopride
- Volunteers
- 466 people
- Sponsor
- Forest Laboratories
Postoperative Ileus
Effect of TU-100 in Patients Undergoing Laparoscopic Colectomy
TU-100 is a gastrointestinal drug produced from the three botanical raw materials, Asian ginseng, Zanthoxylum fruit (Japanese pepper), and ginger, based on proprietary aqueous decoction and granulation technology.
- Trial name
- TU100P2T3 (NCT02232893)
- Testing
- Daikenchuto (TU-100)
- Where
- 13 sites in United States
- Volunteers
- 69 people
- Sponsor
- Tsumura USA
IBS - Irritable Bowel Syndrome, Anxiety
Study to Evaluate the Efficacy of Arrae's Bloat & Calm Alchemy Capsules to Reduce Bloating, Heartburn and Gas, and Alleviate the Intensity of IBS Symptoms
This is an open-label observational crossover trial to study the efficacy of a commercial dietary supplement and its effect on common symptoms of IBS (such as bloating, gas, heartburn, and other symptoms).
- Trial name
- NCT05197413
- Testing
- Arrae bloat supplement
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Arrae