Clinical trials: Bloating
Irritable Bowel Syndrome
The Effect of Probioticson Bloating in IBS
The purpose of the study is to establish an in-vitro method to evaluate the effect of probiotics on gas production in feces (hydrogen and methane)
- Trial name
- NCT00368758
- Testing
- Probiotic bacteria (Trevis R)
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Royal Veterinary and Agricultural University, Denmark
Gas, Bloating
Assessment and Validation of Electronic Gas and Bloating Diary
The investigator's goal is to improve the patient's compliance and accurate capture of patient reported gas and bloating symptoms, by utilizing a phone application that interactively records each gas and bloating event in…
- Conditions
- Gas, Bloating, Distension, Constipation
- Trial name
- NCT04684849
- Testing
- APP Diary, Paper Diary
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Augusta University
Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Combined Lactulose H2-breath Test With Abdominal Imaging
Hydrogen (H₂) breath tests serve several purposes. (i) detect malabsorption of carbohydrates such as lactose and fructose, (ii) measurement of oro-caecal transit time (iii) associate hydrogen production with the onset of…
- Conditions
- Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Breath Tests
- Trial name
- NCT07145580
- Where
- Switzerland
- Volunteers
- 510 people
- Sponsor
- Klinik Arlesheim
Irritable Bowel Syndrome
A Randomized Controlled Pilot Trial of Mesalazine in Patients With Irritable Bowel Syndrome
Emerging evidence indicates the presence of low-grade mucosal inflammation and its pathogenetic role in IBS. The aim of this pilot study is to provide that mesalazine treatment of IBS patients reduces low grade colonic…
- Trial name
- NCT00774007
- Testing
- mesalazine
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- SOFAR S.p.A.
Diabetic Gastroparesis
Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Men With Diabetic Gastroparesis
The purpose of this study is evaluate the safety and efficacy of Metoclopramide Nasal Spray compared to placebo in reducing the symptoms of diabetic gastroparesis in adult men.
- Trial name
- NCT02025751
- Testing
- Metoclopramide Nasal Spray
- Where
- 49 sites in United States
- Volunteers
- 53 people
- Sponsor
- Evoke Pharma
Premenstrual Syndrome, Menstrual Pain
A Clinical Study to Assess the Effect of a Dietary Supplement on Menstrual Cycle Symptoms
This is a single-group, virtual clinical trial evaluating the effects of a daily dietary supplement (DITTO Cycle Supplement) on menstrual cycle symptoms across three menstrual cycles.
- Trial name
- NCT07267728
- Testing
- DITTO Cycle Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muse Nutrition Ltd
Indigestion, Dyspepsia
A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms
The goal of this observational study is to evaluate if Danning Tablets are effective in alleviating dyspepsia in patients with any of the following digestive symptoms: upper abdominal pain, bloating, loss of appetite, acid reflux…
- Conditions
- Indigestion, Dyspepsia, Bloating, Loss of Appetite
- Trial name
- NCT06755671
- Testing
- Danning Tablet
- Where
- China
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Hutchison Pharmaceuticals Limited
Gastrointestinal Health, Immune Health
Effect of Bacillus Subtilis BS50 Supplementation on Gastrointestinal Symptoms in Healthy Adults
The primary objective of this study is to investigate the effect of a novel Bacillus subtilis spore preparation on abdominal bloating, flatulence, and burping in healthy adults.
- Conditions
- Gastrointestinal Health, Immune Health, Cardiovascular Health, Digestive Health
- Trial name
- NCT05004454
- Testing
- Bacillus subtilis BS50 spore preparation, Maltodextrin
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- BIO-CAT Microbials, LLC
Gastrointestinal Disease, Flatulence
Evaluation of Gastrointestinal Symptoms Following Chilean Native Beans Consumption
The oligosaccharide content (raffinose, stachyose, and verbascose) in legumes would be responsible for gastrointestinal symptoms (bloating, pain, meteorism), associated with its consumption.
- Conditions
- Gastrointestinal Disease, Flatulence, Gastrointestinal Tolerance, Distension; Bowel
- Trial name
- NCT04243187
- Testing
- Chilean Native Beans
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Natalia Jara
Digestive Health, Abdominal Discomfort
Study to Investigate the Efficacy of a Digestive Health Dietary Supplement on Post-meal Bloating in Healthy Participants
The goal of this crossover clinical trial is to evaluate the efficacy and safety of Bloat Gummies on postprandial bloating and related gastrointestinal discomfort in healthy adults with recurrent bloating.
- Conditions
- Digestive Health, Abdominal Discomfort, Gas and Bloating
- Trial name
- NCT07516587
- Testing
- Bloat Gummies
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arrae
Neuromuscular Blockade
Influence of Analgesia and Neuromuscular Block on Abdominal Distension and Operating Conditions Laparoscopic Operations
Neuromuscular block improves operation conditions during laparoscopic surgery. In this study, a new measurement tool is assessed: the degree of abdominal distension during the time course of the neuromuscular block is measured…
- Trial name
- NCT03605628
- Testing
- measuring tape, neuromuscular block, Surgical rating score
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Kreiskrankenhaus Dormagen
Bloating, Digestive Discomfort
A Clinical Trial to Examine the Effects of Gut Health Supplements to Improve Gut and Digestive Health and Function
This is a double-blind, randomized, placebo-controlled trial evaluating the efficacy of JSHealth's Debloat \& Detox supplement, used alone or in combination with their Probiotics supplement, on gut and digestive health and…
- Conditions
- Bloating, Digestive Discomfort, Irritable Bowel Syndrome (IBS), Flatulence
- Trial name
- NCT07902882
- Testing
- Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- JS Health & Vitamins
Irritable Bowel Syndrome, Dyspepsia
Visible Abdominal Distension
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06369753
- Testing
- Biofeedback
- Where
- 7 sites in United States, Canada and 5 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Abdominal Distention, Abdominal Bloating
Clinical Characteristics of Small Intestinal Bacterial Overgrowth in Individuals With Abdominal Bloating/Distention
Abdominal bloating/distention represents a prevalent clinical manifestation characterized by an unclear etiology and pathogenesis.
- Trial name
- NCT06285734
- Testing
- Breath test
- Where
- China
- Volunteers
- 387 people
- Sponsor
- Shandong University
Constipation - Functional, Abdominal Pain (AP)
Co-Development and Validation of Colonic Symptom Pictograms for Young People
Severe constipation affects 10% of children, often leading to significant physical and emotional distress. While constipation is commonly associated with impaired bowel movements, it is fundamentally linked to abnormalities in…
- Conditions
- Constipation - Functional, Abdominal Pain (AP), Nausea and Vomitting, Bloating
- Trial name
- NCT07337343
- Testing
- Pictogram comprehension and validation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Auckland, New Zealand
Bloating
Treatment of Symptomatic Bloating Using a Novel Hypnotherapy Protocol
The purpose of this research is to evaluate if hypnotherapy delivered electronically will help with bloating symptoms.
- Trial name
- NCT05572606
- Testing
- Hypnotherapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Mayo Clinic
Abdominal Pain, Abdominal Discomfort
Pilot Study Studying Physiological Effects of Probiotic Pills in Patients With Abdominal Pain/Discomfort and Bloating
We are conducting a study to learn if probiotics, which are live bacteria found in food like yogurt and cheese, will improve symptoms of abdominal pain.
- Conditions
- Abdominal Pain, Abdominal Discomfort, Bloating, Functional Bowel Disorders
- Trial name
- NCT01064661
- Testing
- Single probiotic arm of L-NCFM alone, Blend probiotic arm of L-NCFM and B-LBi07
- Volunteers
- 22 people
- Sponsor
- University of North Carolina, Chapel Hill
Irritable Bowel Syndrome (IBS)
Abdominal Symptom Phenotype Study in Children
Children and adults commonly suffer from recurrent abdominal (stomach) pain. One type is called irritable bowel syndrome (IBS). IBS in adults and children is one of the most common and costly health care problems in the US.
- Trial name
- ASPPNB (NCT01204515)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Bloating, Gastrointestinal Symptoms
A Clinical Trial to Investigate the Safety and Efficacy of Bloat on Postprandial Bloating and Its Effects Over Time in Healthy Women
The goal of this clinical trial is to investigate the safety and efficacy of Bloat on postprandial bloating in healthy women. The main question it aims to answer is what is the difference in change in bloating from pre-dose…
- Conditions
- Bloating, Gastrointestinal Symptoms, Intestinal Gas
- Trial name
- NCT07370740
- Testing
- Bloat
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Arrae
Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Comparison of the Efficacy of Saccharomyces Boulardii and Rifaximin in the Treatment of Small Intestinal Bacterial Overgrowth
This multicenter randomized controlled study aims to systematically evaluate the efficacy and safety of Saccharomyces boulardii sachets versus rifaximin in the treatment of small intestinal bacterial overgrowth (SIBO), with a…
- Trial name
- NCT07815548
- Testing
- Saccharomyces boulardii sachets, Rifaximin (Xifaxan)
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Shandong University