Clinical trials: Block Level
ARDS, TTM
TwichView-guided Atricurium Dose Adjustment Trial
The goal of this clinical trial is to learn if using a monitor that measures muscle response can lower the amount of muscle relaxant medicine needed in adults who are treated in an intensive care unit (ICU) and need a continuous…
- Conditions
- ARDS, TTM, ECMO, Neuromuscular Blockade Monitoring
- Trial name
- NCT07807046
- Testing
- EMG-based quantitative TOF-guided atracurium titration
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Fu Jen Catholic University Hospital
Sick Sinus Syndrome, Complete Atrioventricular Block
Zero-fluoroscopic Navigation Versus Conventional Fluoroscopic Navigation for Single-chamber Pacemaker Implantation
This study is intended to compare the feasibility, safety and efficacy of Ensite-NavX zero-fluoroscopic navigation system to conventional fluoroscopic X-ray approach as to performing single-chamber pacemaker implantation.
- Conditions
- Sick Sinus Syndrome, Complete Atrioventricular Block, High Degree Second Degree Atrioventricular Block, Bradycardia
- Trial name
- ZF-PMSC (NCT03118440)
- Testing
- zero-fluoroscopy 3D navigation, conventional x-ray navigation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Obstructive Sleep Apnea of Newborn
Nasal and Oronasal Mask in Severe OSA Patients With Nasal Free Airflow of Obstruction
The obstructive sleep apnea (OSA) affects between 10% to 25% of the adults. Continuous positive airway pressure (CPAP) is the first choice of treatment in severe OSA.
- Trial name
- NCT02274194
- Testing
- Nasal CPAP, Oronasal CPAP
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postoperative Pain
Circumflex Nerve Blocks Versus Posterior Cord Nerve Blocks in Shoulder Arthroscopy
Shoulder arthroscopy is associated with severe postoperative pain. Traditionally, the interscalene approach to the brachial plexus has been employed to manage postoperative pain following shoulder surgery.To provide more complete…
- Trial name
- NCT04446403
- Testing
- Suprascapular Nerve Block, Axillary Nerve Block, posterior cord block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Bassant M. Abdelhamid
Airway Management, Neuromuscular Blockade
Effect of Neuromuscular Blockade on Video Laryngeal Mask Airway Ventilation
This prospective, randomized, double-blind study aims to evaluate the effect of different degrees of neuromuscular blockade on the performance of a video laryngeal mask airway (LMA) during general anesthesia.
- Conditions
- Airway Management, Neuromuscular Blockade, General Anesthesia
- Trial name
- NCT07828977
- Testing
- Normal Saline (Rocuronium 0 mg/kg), Rocuronium 0.3 mg/kg, Rocuronium 0.6 mg/kg
- Volunteers
- 96 people
- Sponsor
- Korea University Guro Hospital
Aortic Stenosis, Heart Failure
High-Sensitivity Troponin T Plasma Levels in Patients With Aortic Stenosis (Tyrolean Aortic Stenosis Study-2)
TASS-2 (Tyrolean Aortic Stenosis Study-2) aims to characterize the clinical value of minimally elevated troponin T plasma levels both in patients with asymptomatic and symtomatic aortic stenosis.
- Conditions
- Aortic Stenosis, Heart Failure, Syncope, Angina Pectoris
- Trial name
- TASS-2 (NCT02448485)
- Testing
- Aortic Valve Intervention (surgical or transcatheter)
- Where
- Austria
- Volunteers
- 10,000 people
- Sponsor
- Medical University Innsbruck
Back Pain, Surgery-Complications
Analgesic Requirement for Post-Operative Pain Control in TLIP Interbody Fusion
The goal of this clinical trail is to to compare the efficacy of thoracolumbar interfascial plane block with Exparel vs with standard of care 0.25% Bupivacaine HCl in patients undergoing 1-3 level elective transforaminal lumbar…
- Conditions
- Back Pain, Surgery-Complications, Narcotic Use, Physical Stress
- Trial name
- NCT06350981
- Testing
- Exparel, Bupivacain
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Foundation for Orthopaedic Research and Education
First Degree AV Block
Restoration of Atrioventricular Synchrony Trial
The objective of the trial is to observe the effects of restoring atrioventricular (AV) synchrony in subjects with prolonged PR intervals.
- Trial name
- RESTORE-AV (NCT01275833)
- Testing
- Cardiac resynchronization therapy-defibrillator
- Volunteers
- 2 people
- Sponsor
- Boston Scientific Corporation
Anesthesia , Analgesia
Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery
Posterior spinal fusion for scoliosis surgery may lead to severe postoperative pain which requires significant opioid use for adequate perioperative analgesia.
- Trial name
- NCT05671081
- Testing
- Dexmedetomidine, Magnesium sulfate, Narcotic Analgesics
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Coronary Artery Spasm, Autonomic Dysfunction
The Effect of Autonomic Function on Coronary Vasomotion
Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm (CAS), but few studies have been published about the relationship between CAS and BP, with the exception of…
- Trial name
- NCT01877993
- Where
- 3 sites in South Korea
- Volunteers
- 2,169 people
- Sponsor
- Korea University
Neuromuscular Blockade
Study on the Level of Neuromuscular Blockade
On the basis of moderate pneumoperitoneum pressure(10 mmHg), this study evaluates the effect of different level of neuromuscular blockade to gastrointestinal barrier function during laparoscopic gastrectomy.
- Trial name
- NCT03782233
- Testing
- A continuous intravenous infusion of 0.5-0.6 mg/kg/h Rocuronium Bromide Intravenous Solution (50 Mg/5 mL) to keep the target neuromuscular blockade (PTC = 1-2)., A continuous intravenous infusion of 0.2-0.3 mg/kg/h Rocuronium Bromide Intravenous Solution (50 Mg/5 mL) to keep the target neuromuscular blockade (TOF = 1-2).
- Where
- China
- Volunteers
- 83 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Sick Sinus Syndrome, Atrioventricular Block, Second and Third Degree
Evaluating the Safety and Effectiveness of 5G Cloud Follow-up for Cardiovascular Implantable Electronic Devices
Objective: This clinical study employs a prospective, paired, self-controlled, non-inferiority, multicenter research design to assess the safety and efficacy of utilizing 5G cloud follow-up for CIED in parameters monitoring and…
- Conditions
- Sick Sinus Syndrome, Atrioventricular Block, Second and Third Degree, Heart Failure
- Trial name
- CIED-CARE (NCT06652750)
- Testing
- Routine Management, 5G Cloud Follow-up
- Where
- 2 sites in China
- Volunteers
- 688 people
- Sponsor
- The Third People's Hospital of Chengdu
Knee Arthropathy, Knee Osteoarthritis
NLR and PLR Levels Following IPACK Block in Knee Arthroplasty
Effect of iPACK block on NLR and PLR following knee arthroplasty
- Conditions
- Knee Arthropathy, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT06304298
- Testing
- 0.9% Sodium Chloride Injection, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Dexmedetomidine, Femoral Nerve Block
Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Block.
The duration of sensory block after single dose of long acting local anesthetics is not sufficient to avoid the postoperative use of opioids.
- Conditions
- Dexmedetomidine, Femoral Nerve Block, Arthroscopic Knee Surgery
- Trial name
- NCT02089932
- Testing
- peri-neural dexmedetomidine as adjuvant to bupivacaine in femoral nerve block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Sinus Node Disease, Atrioventricular; Block, Second Degree (Types I and II)
Physiological Ventricular Pacing Vs Managed Ventricular Pacing for Persistent AF Prevention in Prolonged AV Interval
A multicenter, prospective, randomized study in a 1:1 ratio, single-blind with double-blind evaluation to evaluate the superiority of physiological ventricular pacing (proposed modality) vs.
- Trial name
- PhysioVP-AF (NCT05367037)
- Testing
- PhysioVP, DDD-VPA
- Where
- Italy
- Volunteers
- 640 people
- Sponsor
- Quovadis Associazione
Anesthesia
Decision Support System for Anesthetists
The balanced anesthesia process contains three main parts: the control of hypnosis, analgesia, and neuromuscular blockade. For the induction phase, the anesthesiologist performs protocols based on prior planning specific to each…
- Trial name
- Serenity (NCT04079036)
- Where
- Brazil
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Aortic Stenosis Disease
Impact of Enhanced Information on Subjective Information Level and PROMs in Patients with Aortic Stenosis
The aim of this trial is to evaluate if an enhanced information by using a mobile App can increase subjective information level in patients with severe aortic stenosis and may therefore improve patient-reported outcomes.
- Trial name
- TAVI-SDM-APP (NCT06706635)
- Testing
- Application of App
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
ASTHMA
Breathing Training for Asthma
For the proposed randomized controlled treatment study, the investigators plan to compare the effects of this hypoventilation-based breathing training with a control intervention that will focus on breathing regularity and…
- Trial name
- NCT00975273
- Testing
- Capnometry Assisted Respiration Training, Breathing Awareness
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Southern Methodist University
High BMI
A Comparative Study of Supine Position and the Head Elevated Position on the Level of Sensory Block After Spinal Anesthesia in Morbidly Obese Parturient Undergoing Elective Cesarean Delivery
The sniffing position defined as neck flexion with upper cervical extension, is traditionally recommended for general anesthesia induction, as it improves laryngoscopic views.
- Trial name
- NCT06889337
- Testing
- head elevated laryngoscopy position by Oxford pillow
- Where
- Qatar
- Volunteers
- 90 people
- Sponsor
- Hamad Medical Corporation
Benign Prostatic Hyperplasia, Bladder Outlet Obstruction
Urinary CTGF in Benign Prostatic Obstruction
Benign prostatic obstruction (BPO) is one of the most common causes of bladder outlet obstruction (BOO) and may lead to progressive structural and functional alterations in the bladder over time.
- Conditions
- Benign Prostatic Hyperplasia, Bladder Outlet Obstruction, Lower Urinary Tract Symptom
- Trial name
- NCT07416981
- Volunteers
- 50 people
- Sponsor
- Tarik Emre Sener