Clinical trials: Block Level
Atrioventricular Block, Second and Third Degree
Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post TAVI
The study aims to compare permanent Conduction System Pacing (CSP) with the standard therapy - Right Ventricular Pacing (RVP) or Biventricular Pacing (BVP) - in preventing the development and progression of symptomatic Chronic…
- Trial name
- PACE-4-TAVI (NCT05966675)
- Testing
- conduction system pacing, right ventricular or biventricular pacing
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Medical University of Silesia
Aortic Valve Disease, Conduction Disturbances
Ambulatory Electrocardiographic Monitoring for the Detection of High-Degree Atrio-Ventricular Block in Patients With New-onset PeRsistent LEft Bundle Branch Block After Transcatheter Aortic Valve Implantation. The "MARE" Study
The purpose of this study is to determine the incidence and predictors of high degree or complete atrioventricular block (AVB) (paroxysmal or persistent) in patients with new-onset persistent left bundle branch block (NOP-LBBB)…
- Trial name
- MARE (NCT02153307)
- Testing
- Implantable loop recorders system Reveal ICM LINQ®,
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Acute Pain, Spinal Stenosis
Quadro-Iliac vs Thoracolumbar Interfascial Plane Block for Analgesia After Single-Level Lumbar Disc Surgery
The investigators aim to compare the postoperative analgesic efficacy of the classical thoracolumbar interfascial plane block and the Quadro-iliac plane block for postoperative analgesia management after lumbar disc surgery.
- Trial name
- NCT07348419
- Testing
- Quadro-iliac plane block, Classical thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Samsun University
Spinal Anesthesia Evaluation, Cesarean Delivery
Dose-to-block Level Relation in Single Shot Spinal Anesthesia for Cesarean Section.
The study is designed to support or deny relation between the dose of hyperbaric bupivacaine given intrathecally and extent of spinal block level.
- Trial name
- SpinDoBlock (NCT06729567)
- Testing
- Spinal block level analysis, data collection
- Where
- Poland
- Volunteers
- 362 people
- Sponsor
- Centre of Postgraduate Medical Education
Breast Cancer
Subpectoral Plexus Block With Multi-level TPVB for Surgical Anesthesia During Primary Breast Cancer Surgery
The objective of this study is to compare two different doses of local anesthetics (10ml vs 20ml of 0.25% levobupivacaine) for subpectoral plexus block (SPPB) in addition to ultrasound guided multi-level of thoracic paravertebral…
- Trial name
- NCT04933266
- Testing
- Subpectoral plexus block (low dose), Subpectoral plexus block (High dose)
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Chinese University of Hong Kong
Retinal Vein Occlusion
Vascular Endothelial Growth Factor (VEGF) Levels in Retinal Vein Occlusion (RVO) During Anti-VEGF Treatment
The purpose of this study is to treat patients with retinal vein occlusion with standard of care anti-vascular endothelial growth factor therapy and to correlate levels of vascular endothelial growth factor in the anterior…
- Trial name
- NCT04707625
- Testing
- Aflibercept Ophthalmic
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Pain
Evaluation of Effectivity of Erector Spina Plane Block With Different Levels
In last years, erector spinae plane block is widely used in abdominal and thoracic surgeries. Laparoscopic cholecystectomy is one of the most commonly performed surgical operations.
- Trial name
- NCT04316416
- Testing
- T7 Level Erector Spinae Plane Block, T9 Level Erector Spinae Plane Block, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Healthy
Effects of a Novel Supplement on Glycemic Variability Measured by Continuous Glucose Monitoring
This is a two-cohort, crossover pilot study to determine interstitial glucose levels coincident with the consumption of a novel carbohydrate blocking supplement.
- Trial name
- NCT05832463
- Testing
- Carbohydrate blocking supplement (CBS)
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
Knee Arthropathy
Pain Levels and Opioid Usage in Three Nerve Block Cohorts in Primary TKA
The primary objective of this study is to compare effect of combined block of ACB (adductor canal block) with IPACK (Interspace between the Popliteal Artery and the Capsule of the posterior Knee) block and/or Intra-articular…
- Trial name
- NCT04292392
- Testing
- preop ACB, followed by Intra-articular block during TKA surgery, preop ACB+IPACK block, preop ACB+IPACK block, followed by Intra-articular block during TKA surgery
- Where
- United States
- Sponsor
- University of Louisville
Lung Cancer (Diagnosis)
Combination Versus Alone Liposomal Bupivacaine Blocks in Minimally Invasive Thoracic Surgery-1
The goal of this clinical trial is to assess how the location of local anesthetic medication affects pain control capabilities in adult patients undergoing thoracic(chest)-only minimally invasive surgery.
- Trial name
- CALMS-1 (NCT07254650)
- Testing
- Arm 1 "LipoB-I": Liposomal Bupivacaine via Multi-Level Intercostal Nerve Block, Arm 2 "LipoB-S": Liposomal Bupivacaine via Serratus Anterior Plane Block, Arm 3 "LipoB-C": Liposomal Bupivacaine Administered via Combination Block
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Texas Southwestern Medical Center
First Degree Atrioventricular Block
BiventRicular Pacing in prolongEd Atrio-Ventricular intervaL: the REAL-CRT Study
This study was designed to evaluate the potential benefits of treatment with biventricular device in patients with normal systolic function , indication for pacing and impaired atrio-ventricular conduction , by comparing the…
- Trial name
- REAL-CRT (NCT02150538)
- Testing
- Cardiac resynchronization therapy pacemaker, Dual chamber pacemaker
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- Gianluca Botto
Postoperative Pain, Percutaneous Nephrolithotomy
The Effectiveness of Quadro İliac Plane Block in Percutaneous Nephrolithotomies
Our aim was to investigate the effect of quadro iliac plane block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy surgery and to determine which areas of the skin this block anesthetizes.
- Trial name
- NCT07203859
- Testing
- Quadro-İliac Plane Block(QİPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Pulmonary Hypertension
Effect of Endothelin-1 Receptor Blockade on Circulating Endothelial Microparticles Levels in Patients With Pulmonary Hypertension
Pulmonary hypertension is a progressive and life threatening condition. It is characterized by severe remodeling of the pulmonary vessel wall, obstructive plexiform lesions, multi-focal thrombosis, and enhanced vasoconstriction.
- Trial name
- NCT00675051
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Pain, Postoperative, Breast Surgery
One-level and Bi-level ESPB Application in Patients Undergoing Breast Surgery
Acute pain after breast surgery can significantly reduce the quality of life for patients. If acute pain is not adequately treated, it can develop into chronic pain.
- Conditions
- Pain, Postoperative, Breast Surgery, Erector Spinae Plane Block, Multimodal Analgesia
- Trial name
- NCT07747623
- Testing
- One-level Erector Spinae Plane Block, Bi-level Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Atrial Fibrillation, Atrioventricular Block, Second and Third Degree
Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG
During the preoperative examination, in addition to the standard examination recommended before high-risk cardiac surgeries, a digital single-lead ECG is recorded using portable CardioQUARK devices.
- Conditions
- Atrial Fibrillation, Atrioventricular Block, Second and Third Degree, Sinus Node Dysfunction, Ventricular Tachycardia (VT)
- Trial name
- NCT07348991
- Testing
- digital single-channel ECG recording
- Volunteers
- 300 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Postoperative Pain
Deep Parasternal Intercostal Plane (DPIP) Block
In this study, we aimed to compare the effects of this block, which is routinely applied in our hospital but has not been studied in our hospital or in the literature before, on the pain in the first 24 hours after the operation…
- Trial name
- NCT06558123
- Testing
- block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istinye University
Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain
QLESP Block for Pain Control in Robotic Partial Nephrectomy
The goal of this clinical trial is to learn if an ultrasound-guided nerve block called QLESP works to reduce pain and the need for strong pain medicines after robotic kidney surgery in adults.
- Conditions
- Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain, Nerve Block
- Trial name
- NCT07704970
- Testing
- ropivacaine (local infiltration), ropivacaine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Combined Spinal Epidurai Anesthesia, Lower Extremity Surgery
the Relationship Between Vertebral Body Length, Subarachnoid Space Width and Block Level
Spinal anesthesia technology has been widely used in various surgeries and multi-mode analgesia. Spinal ultrasound imaging has been proved to be a reliable tool for evaluating spinal parameters.
- Trial name
- NCT05201261
- Testing
- ltrasonic measure
- Volunteers
- 50 people
- Sponsor
- Shengjing Hospital
Cesarean Section, Pregnancy
Intra-abdominal Pressure, Abdominal Circumference, and Spinal Block Level in Cesarean Section
Spinal anesthesia is commonly used for cesarean section and provides effective anesthesia with rapid onset. However, the spread of spinal anesthesia may vary among pregnant women due to physiological and anatomical changes during…
- Conditions
- Cesarean Section, Pregnancy, Elective Cesarean Section
- Trial name
- NCT07406373
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Kutahya Health Sciences University
Pain, Chronic
Comparison of Pain Relief After Upper and Lower Lumbar Erector Spinae Plane Block
The primary endpoint of this study was to identify if eretor spinae plane block (ESPB) has any effect in relieving low back pain or leg pain in lumbar radiculopathy.
- Trial name
- NCT05487339
- Testing
- Erector spinae plane block
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Keimyung University Dongsan Medical Center