Clinical trials: Block Level
Pain, Postoperative, Analgesia
Evaluation of Multimodal Analgesia With NOL
The study will include 80 patients undergoing Laparoscopic Cholecystectomy Surgery as part of elective requirements. The study is a single-center, prospective, randomized controlled trial The aim of the study is 1.
- Trial name
- NCT06238830
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Opioid Use Disorder
Multiple Dose Study of Blockade of Opioid Effects by Injections of Buprenorphine in Participants With Opioid Disorder
This is a multiple-dose study in non-treatment seeking male and female subjects with moderate to severe opioid use disorder who meet criteria from the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) to…
- Trial name
- NCT02044094
- Testing
- Buprenorphine, buprenorphine and naloxone, hydromorphone
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Indivior Inc.
Hand Surgery, Ultrasound Guided
A Comparative Study Between Infraclavicular and Axillary Blocks for Assessment of Motor Power Using Handgrip Dynamometer
Hand Surgery is surgery of the hand, the wrist, and the peripheral nerves of the upper limb. Many different types of surgeries can be performed on the hand, depending on the underlying cause of the problem such as Closed…
- Trial name
- NCT05325372
- Testing
- axillary block, infraclavicular block
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Occipital Neuralgia, Cervicogenic Headache
Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block
This study will compare the analgesic benefit of a traditional landmark-guided GON block with the ultrasound-guided approach over a four week period in patients with occipital neuralgia or cervicogenic headache.
- Conditions
- Occipital Neuralgia, Cervicogenic Headache, Migraine Without Aura
- Trial name
- NCT03478735
- Testing
- Ultrasound Guided Greater Occipital Nerve Block at C2, Landmark-Based Greater Occipital Nerve Block
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Voice Disorders
Voice Therapy With a Semi-occluded Vocal Tract
1. The first objective of this research is to investigate the immediate effects of three semi-occluded vocal tract (SOVT) exercises (straw phonation in air, straw phonation in 2cm water, and straw phonation in 5cm water) on…
- Trial name
- NCT06137131
- Testing
- Straw phonation in air, straw phonation in water, /u/ phonation
- Where
- Belgium
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hip Dysplasia
SII Levels Following PENG Block in Pediatric Hip Surgery
This study is a prospective, randomized, double-blind clinical trial. Its aim is to evaluate whether adding a pericapsular nerve group (PENG) block to spinal anesthesia can reduce the inflammatory response after hip surgery in…
- Trial name
- NCT07607535
- Testing
- Ropivacaine 0.2% Injectable Solution, 0.9%NaCl
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
High Degree AV-block, Left Bundle Branch Block
QT Interval in Patients With Pacemaker Dependency
The aim of this study is to examine a correction term for an adapted QT interval during ventricular pacing (right, left and biventricular pacing) to obtain valid formulae correcting for the QT intervals in various pacing…
- Trial name
- QT-TENDENCY (NCT01694550)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- University of Magdeburg
Heart Block Complete, Heart Block Second Degree
Slow Heart Registry of Fetal Immune-mediated High Degree Heart Block
Few studies are specifically designed to address health concerns that are already relevant during pregnancy. The consequence is a lack of evidence on best clinical practice.
- Trial name
- NCT04559425
- Testing
- Dexamethasone, No Dexamethasone
- Where
- 27 sites in United States, Bulgaria and 10 more
- Volunteers
- 350 people
- Sponsor
- The Hospital for Sick Children
Sleep Apnea
Influence of Didgeridoo Practice on UA Obstruction Levels in Moderate OSA
Didgeridoo practice has been shown to improve OSA severity. The aim of our study is to assess the changes in upper airways obstruction levels before and after Didgeridoo practice in moderate OSA patients.
- Trial name
- NCT02159664
- Testing
- didgeridoo practice
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Sick Sinus Syndrome, Complete Atrioventricular Block
Zero-fluoroscopic Navigation Versus Conventional Fluoroscopic Navigation for Double-chamber Pacemaker Implantation
This study is intended to compare the feasibility, safety and efficacy of Ensite-NavX zero-fluoroscopic navigation system to conventional fluoroscopic X-ray approach as to performing double-chamber pacemaker implantation.
- Conditions
- Sick Sinus Syndrome, Complete Atrioventricular Block, High Degree Second Degree Atrioventricular Block (Disorder), Bradycardia
- Trial name
- ZF-PMDC (NCT03118427)
- Testing
- zero-fluoroscopy 3D navigation, conventional x-ray navigation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tongji Hospital
Hip Osteoarthritis
SII Levels Following PENG Block in Hip Arthroplasty
This randomized controlled trial evaluates the effect of ultrasound-guided Pericapsular Nerve Group (PENG) block on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal…
- Trial name
- NCT07449403
- Testing
- sodium Chloride, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Chronic Obstructive Pulmonary Disease
Long-term Safety, Tolerability and Efficacy of Aclidinium Bromide in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) (LAS-MD-35)
The purpose of this study is to evaluate the safety, tolerability and efficacy of inhaled aclidinium bromide at two dose levels in patients with moderate to severe, stable chronic obstructive pulmonary disease.
- Trial name
- LAS-MD-35 (NCT01044459)
- Testing
- Aclidinium Bromide 200 µg, Aclidinium Bromide 400 µg
- Where
- 113 sites in United States, Canada
- Volunteers
- 605 people
- Sponsor
- AstraZeneca
Opioid-Related Disorders
Assessment of Tramadol as a Treatment for Opioid Addiction
Opioids are one of the most commonly abused drugs among individuals who seek treatment for drug abuse. Thus, it is necessary to develop new treatments for opioid addiction.
- Trial name
- NCT00301210
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Johns Hopkins University
Nerve Blocks
PECS Block: Plasma Bupivacaine Level
The purpose of this study is to determine peak plasma bupivacaine concentrations in a similar fashion for PECS I/II blocks. The investigators hypothesis is that the mean peak plasma levels for patients undergoing PECS I/II blocks…
- Trial name
- NCT03059498
- Testing
- Unilateral PECS I and II block, Bilateral PECS I and II block, Bupivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Wake Forest University Health Sciences
Hearing Loss
Impact of Interscalenous Block Anesthesia on Hearing
Interscalene brachial plexus block (ISBPB) is used frequently in shoulder, clavicle and upper arm surgeries to obtain analgesia in the postoperative period.
- Trial name
- NCT06430463
- Testing
- pure tone audiometry levels
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Karaman Training and Research Hospital
Cesarean Section, Anesthesia, Obstetric
Evaluation of the Typical Spinal Block During Cesarean Delivery
This will be a prospective, observational, single-center study to evaluate the accuracy of sensory testing by blunt 16-gauge plastic cannula during the 15 minutes after spinal injection for predicting spinal failure.
- Trial name
- NCT06206044
- Testing
- Intrathecal 1.6 ml 0.75% bupivacaine in 8.25% dextrose combined with 15 mcg fentanyl and 150 mcg preservative-free morphine
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Oregon Health and Science University
Constipation by Outlet Obstruction
Defecation Patterns in Constipated Patients
Chronic constipation (CC) is a common condition that affects up to 25% of the population in North America. It poses a major burden on the healthcare cost.
- Trial name
- NCT04903470
- Testing
- Bisacodyl, Atropin
- Where
- 2 sites in United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The California Medical Innovations Institute, Inc.
Respiratory Failure
Inspiratory Effort at Different Expiratory Cycling and Airway Resistance During Pressure Support Ventilation (CYCLOPES)
The goal of this prospective interventional crossover randomized physiological study is to investigate the reliability of Pressure Muscle Index (PMI) - as an estimation of inspiratory effort - at different levels of expiratory…
- Trial name
- CYCLOPES (NCT05952726)
- Testing
- Expiratory cycling change at different levels of pressure support ventilation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione IRCCS San Gerardo dei Tintori
Cardiac Index
Effects of Neuromuscular Blockade Level and Intra-abdominal Pressure on Surgical Conditions and Cardiopulmonary Responses During Laparoscopic Colon Surgery With the Trendelenburg Position
The purpose of this study is to find out the effect of low abdominal pressure vs. standard abdominal pressure on the cardiac and respiratory function of the patients undergoing laparoscopic colon surgery in Trendelenberg…
- Trial name
- NCT02249585
- Testing
- Standard abdominal pressure, Low abdominal pressure, Conventional neuromuscular blockade
- Where
- South Korea
- Volunteers
- 131 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer, Pain Management
Effect of Rectus Block Timing on Opioid Use
The aim of this study is to observe the effect of administering local anesthetic to the abdominal wall at the beginning or end of surgery under general anesthesia on opioid consumption during surgery.
- Conditions
- Prostate Cancer, Pain Management, Nociception Level Index(NoL), Nociception Monitoring
- Trial name
- PROSTIMERSBOP (NCT07433140)
- Testing
- Early bilateral rectus sheat block, Late bilateral rectus sheat block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Koc University Hospital