Clinical trials: Blockades Neuromuscular
Neuromuscular Blockade, Anesthesia
Evaluation of Intubation Conditions Following BX1000 or Rocuronium in Subjects Undergoing Surgery
Assessment of Intubation conditions following administration of neuromuscular blocking agents; BX1000 (investigational) or rocuronium (active control).
- Conditions
- Neuromuscular Blockade, Anesthesia, Surgery
- Trial name
- NCT05687253
- Testing
- BX1000, Rocuronium Bromide
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baudax Bio
Neuromuscular Blockade
Comparison of Onset of Neuromuscular Blockade With Electromyographic and Acceleromyographic Monitoring
The purpose of this research is to use 2 devices to compare the difference in the amount of time it takes for each device to register complete muscle relaxation after the muscle relaxing medication is given.
- Trial name
- NCT05120999
- Testing
- Train of four measurement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Vocal Cord Paralysis, Recurrent Laryngeal Nerve
Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery
Thyroidectomy is a frequently performed surgeon by the head and neck and endocrine surgeons. In recent years, surgical techniques and technological developments have resulted in a significant reduction in complication rates.
- Trial name
- NCT03634956
- Testing
- Group B. Sugammadex sodium-IONM
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Obesity
Comparison of Acceleromyography and Electromyography in Obese Patients Undergoing General Anesthesia
The goal of this prospective observational study is to compare two different methods of monitoring muscle relaxation during anesthesia - acceleromyography (AMG) and electromyography (EMG) - in people with obesity who are having…
- Trial name
- OBAEG (NCT07283354)
- Testing
- Neuromuscular monitoring with electromyography (EMG), Neuromuscular monitoring with acceleromyography (AMG)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
End Stage Renal Disease on Dialysis
Fight Fatigue: A Progressive Muscle Relaxation and Walking Intervention to Reduce Fatigue in Adults With ESKD
Fight Fatigue is evaluating the feasibility and acceptability of a combined progressive muscle relaxation and walking intervention to reduce fatigue for adults with end-stage kidney disease receiving in-center hemodialysis.
- Trial name
- NCT07014111
- Testing
- Fight Fatigue, Attention Control
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Illinois at Chicago
Knee Osteoarthritis, Total Knee Arthroplasty
Adherence to Home-Based Physiotherapy and Music-Assisted Relaxation After Total Knee Arthroplasty
This randomized controlled study evaluated adherence to two home-based programs after total knee arthroplasty. All participants received a structured home-based physiotherapy program for 6 weeks.
- Trial name
- NCT07705971
- Testing
- Home-Based Physiotherapy, Music-Assisted Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Pamukkale University
Kidney Failure, Acute, Myopathy; Drugs
The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)
The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure.
- Conditions
- Kidney Failure, Acute, Myopathy; Drugs, Heart Arrhythmia, Succinylcholine Sensitivity
- Trial name
- NCT06707532
- Testing
- Propofol, Rocuronium
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
ARDS
Paediatric Ards Neuromuscular Blockade Study
Paediatric acute respiratory distress syndrome (ARDS) is a manifestation of severe, life-threatening lung injury. Care for paediatric patient is mainly supportive and based on what works in adults and personal experiences…
- Trial name
- PAN (NCT02902055)
- Testing
- Neuromuscular Blocking Agents, Isotonic saline
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- University Medical Center Groningen
Neuromuscular Blockade
Relation Between TOF-Watch® SX and a Peripheral Nerve Stimulator After 4.0 mg.Kg-1 Sugammadex (P05698)
The objective of the trial is to determine the relationship within a participant between the time to manual detection of the reappearance of the fourth twitch (T4) measured using a peripheral nerve stimulator (PNS) and the time…
- Trial name
- NCT00535496
- Testing
- sugammadex
- Volunteers
- 91 people
- Sponsor
- Merck Sharp & Dohme LLC
Low Back Pain
Effect of Progressive Muscle Relaxation Exercises Versus Pilates Exercises on Postnatal Low Back Pain
This study was conducted to compare between the effect of progressive muscle relaxation exercises and the effect of pilates exercises on postnatal low back pain
- Trial name
- NCT06284018
- Testing
- Progressive Muscle Relaxation Exercises, Pilates Exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Gastrointestinal Cancer, Sarcopenia
Sarcopenia and Neuromuscular Block in Gastrointestinal Cancer Surgery
This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery.
- Conditions
- Gastrointestinal Cancer, Sarcopenia, Neuromuscular Blockade
- Trial name
- NCT07003061
- Testing
- Standard Anesthesia Management
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Acute Respiratory Distress Syndrome (ARDS), Intensive Care Units (ICUs)
Assessment of the PEEP Responsiveness to Titrate End-expiratory Pressure and of the Need for Muscle Relaxation During Prone Positioning in Moderate-to-severe Acute Respiratory Distress Syndrome: A Master Protocol
Despite best supportive care, mortality of the Acute Respiratory Distress Syndrom (ARDS) remains high. In the absence of specific treatments, providing safe and efficient mechanical ventilation (MV) is key to survival.
- Trial name
- PEPER (NCT06849570)
- Testing
- Minimal distension, Maximal Recruitment, Prone position + early NMBAs
- Where
- 29 sites in France
- Volunteers
- 1,200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Essential Hypertension
Effect of Breathing and Muscle Relaxation Technique in Individual With Essential Hypertension
Primary hypertension, also called essential hypertension, is a rise in blood pressure (BP) with no identifiable cause. The most prevalent form of hypertension is essential hypertension, which involves 95% of patients with…
- Trial name
- NCT05684666
- Testing
- Slow Breathing Exercise (SBE), Progressive Muscle Relaxation (PMR) Technique
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- King Saud University
Neuromuscular Blockade
Comparison of the TOFscan and the TetraGraph During Recovery of Neuromuscular Function
Assess the values of train-of-four ratios with the TetraGraph and thoses obtained with the TOFscan during recovery of neuromusculat function in surgical patients who have been administred rocuronium.
- Trial name
- DECURAR-EMG (NCT04816539)
- Testing
- TetraGraph
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Abdominal Pain
The Effect of Progressive Muscle Relaxation on Abdominal Pain and Distension in Colonoscopy Patients.
Patients undergoing colonoscopy were divided into progressive relaxation exercises and control groups. Pretest and posttest abdominal pain and distention scores of the patients were determined after colonoscopy.
- Trial name
- NCT04935645
- Testing
- Progressive Muscle Relaxation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Mardin Artuklu University
Neuromuscular Block, Surgery
MRI Measurement of the Effects of Deep Neuromuscular Blockade on the Abdominal Working Space During Laparoscopy
During laparoscopy, a surgical working space is obtained by creation of a pneumoperitoneum. Optimal surgical conditions are essential to ensure the patient's safety.
- Trial name
- RELAX-2 (NCT03287388)
- Testing
- No Rocuronium, Rocuronium (moderate NMB), Rocuronium (deep NMB)
- Volunteers
- 8 people
- Sponsor
- Radboud University Medical Center
Neuromuscular Blockade
The Effect of Deep Block Versus Moderate Block on the Stress Response After Laparoscopic Gastrectomy
This study is a multicenter, randomized, controlled, double-blinded, and parallel design study. A total of 96 patients were decided to be recruited considering a 10% dropout rate.
- Trial name
- suga-SH (NCT02100280)
- Testing
- deep block
- Volunteers
- 96 people
- Sponsor
- Seoul National University Bundang Hospital
Obstructive Sleep Apnea
Sugammadex Compared With Neostigmin/Atropin for Neuromuscular Block Reversal in Patients With Obstructive Sleep Apnea
Incomplete recovery of neuromuscular function after surgery can lead to respiratory complications. Patients with obstructive sleep apnea (OSA) are prone to respiratory complications after surgery.
- Trial name
- NCT02160223
- Testing
- Sugammadex, Neostigmine
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Diskapi Teaching and Research Hospital
Cancer Patients
The Effect of Progressive Muscle Relaxation Exercise on Sleep Quality
Chemotherapy is applied as a standard method in the treatment of cancer, which is an important public health problem in terms of incidence and mortality. Sleep quality due to cancer and its treatments is adversely affected.
- Trial name
- NCT05604820
- Testing
- Progressive Muscle Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- KTO Karatay University
Neuromuscular Blockade Monitoring, NMT
NMT EasyFit Sensor and Cable
The purpose of this clinical study is to collect and assess feedback from clinical users regarding the functionality and device use and collection of raw parameter date from the NMT Sensor and NMT Cable.
- Trial name
- NCT07394140
- Testing
- Collection of NMT Technology
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GE Healthcare