Clinical trials: Blood
Breast Cancer
Blood Test for Early Detection of Breast Cancer Using Todos Medical -Breast 1(TM-B1) Assay
Blood samples from a total of 200 women in two cohorts will be collected and analyzed by TM-B1 assay, which is based on TBIA (Total Biochemical Infrared Analysis) to confirm the presence of cancer.
- Trial name
- TM-B1 (NCT03343691)
- Testing
- Screening Population, Breast Cancer Population
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Todos Medical, Ltd.
Burnout Syndrome, Nurse's Role
The Effects of "Three Good Things" Positive Psychotherapy on Nurses' Burnout
A randomized, controlled trial was conducted for 73 Chineses nurses from The Second Xiangya Hospitcal of Central South University (33 in the experimental group, 40 in the control group).
- Trial name
- NCT03645798
- Testing
- "Three good things" therapy, Normal psychological instruction
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Central South University
HIV Infection, Lymphatic Filariasis
Interaction Between HIV and Lymphatic Filariasis
The impact of lymphatic filariasis (LF) on HIV is assessed by measuring HIV viral load before and after DEC treatment of filariasis in double-infected individuals.
- Trial name
- NCT00295698
- Testing
- Diethylcarbamazine
- Sponsor
- DBL -Institute for Health Research and Development
Hepatitis B
The Effect of Alendronate on the Immune Response to Hepatitis B Vaccine in Healthy Adults
Vaccines are one of our most effective public health tools but many who need them don't respond well and are not protected. Adjuvants boost immune responses and are commonly included in vaccine preparations.
- Trial name
- NCT02057263
- Testing
- Alendronate, Hepatitis B Vaccine
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV Infections
A Peer-Driven Intervention to Increase PrEP Uptake Among Minority MSM
The objective of this study is to develop an effective peer-driven intervention (PDI) approach and assess its feasibility and efficacy on pre-exposure prophylaxis (PrEP) uptake among men who have sex with men.
- Trial name
- NCT05161663
- Testing
- Peer-driven intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
End Stage Renal Disease on Dialysis
The Home Blood Pressure (BP) Trial
The main study will be a two arm 10-month, cross-over randomized controlled trial of 200 participants treated with end-stage-kidney-disease treated with in-center hemodialysis in the Seattle and San Francisco area comparing a…
- Trial name
- Home-BP (NCT05159999)
- Testing
- Dry weight target adjustment, Anti-hypertensive medications
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Washington
Prehypertension
Rice Vinegar as an Intervention to Lower Blood Pressure in Adults With Prehypertension and 10-year CVD Risk <10%
This study is to assess the blood pressure lowering effect of rice vinegar when consumed over a 12-week period by healthy adults ages 30-65 years old with prehypertension.
- Trial name
- Rice-vinegar (NCT03596099)
- Testing
- Mizkan rice vinegar with acetic acid, Mizkan rice vinegar without acetic acid
- Where
- 2 sites in United States
- Volunteers
- 130 people
- Sponsor
- Mizkan Holdings Co., Ltd.
Shoulder Joint Disease, Complications; Arthroplasty
Tranexamic Acid in Reverse Total Shoulder Arthroplasty
To the Investigators' knowledge, TXA has not been studied in the setting of reverse total shoulder arthroplasty. We propose a double-blinded, randomized, controlled trial comparing perioperative administration of TXA to placebo…
- Conditions
- Shoulder Joint Disease, Complications; Arthroplasty, Intraoperative Complications, Blood Loss, Surgical
- Trial name
- TXA (NCT02043132)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Corewell Health East
Bone Demineralization
Alendronate for Prevention of AntiRetroviral Therapy-associated Bone Loss
Antiretroviral therapy (ART) initiation is associated with a significant loss of bone mineral density (BMD), characterised by increases in bone turnover, which is largely limited to the first 48 weeks of therapy.
- Trial name
- APART (NCT02322099)
- Testing
- Alendronate, calcium carbonate and colecalciferol, Tenofovir disoproxil
- Where
- 2 sites in Ireland
- Volunteers
- 53 people
- Sponsor
- University College Dublin
Parkinson Disease
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease.
This study aims to determine if one of three low doses of lithium therapy for 6 months can engage one or more blood-based therapeutic targets implicated in Parkinson's disease (PD) pathophysiology.
- Trial name
- NCT04273932
- Testing
- Lithium
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- State University of New York at Buffalo
HIV Infections
A Study of LIPO-5 and ALVAC-HIV (vCP1452) as Possible HIV Vaccines
This study will test the immune system response to and safety of two HIV vaccines alone and in combination: ALVAC-HIV (vCP1452) and LIPO-5. ALVAC-HIV (vCP1452) uses a canarypox virus with man-made parts of HIV attached to it.
- Trial name
- NCT00076063
- Testing
- ALVAC-HIV (vCP1452), LIPO-5
- Where
- 11 sites in United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Thrombocytopenia, Neonatal Alloimmune
A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)
The purpose of this study is to assess the efficacy and safety of nipocalimab in reducing the risk of severe fetal and neonatal alloimmune thrombocytopenia (FNAIT).
- Trial name
- FREESIA-3 (NCT06533098)
- Testing
- Nipocalimab, Intravenous immunoglobulins (IVIG), Prednisone
- Where
- 38 sites in United States, Austria and 9 more
- Volunteers
- 50 people
- Sponsor
- Janssen Research & Development, LLC
Hepatitis C Chronic, Hepatitis C
Implementation of a Re-engagement Program for Hepatitis C Patients Lost to Follow-up in Argentina.
Hepatitis C virus (HCV) is a leading cause of morbidity and mortality worldwide. This infection continues to represent a major global public health concern.
- Trial name
- NCT06373198
- Testing
- standard of care
- Volunteers
- 800 people
- Sponsor
- Hospital El Cruce
Psoriasis Vulgaris
Oral Chinese Herbal Medicine for Psoriasis Vulgaris With Blood Stasis Syndrome
We designed this study as a multicenter, randomized, double blinded and placebo-controlled clinical trial. The aim of the study is to evaluate the clinical efficacy, safety and control of recurrence rate of psoriasis with blood…
- Trial name
- NCT03942198
- Testing
- Taodan Granules
- Where
- 5 sites in China
- Volunteers
- 216 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Severe Sepsis
4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock
Data on 4G/5G polymorphism of plasminogen activator inhibitor-1 (PAI-1) gene are limited in Asian patients with sepsis. Therefore, the investigators aim to prospectively investigate the incidence of 4G/5G polymorphism and its…
- Trial name
- NCT01211899
- Volunteers
- 160 people
- Sponsor
- Hallym University Medical Center
Hemophilia A
A Study to Evaluate the Safety and Tolerability of Prophylactic Emicizumab in Hemophilia A Patients With Inhibitors
This is a phase IIIb, single arm, open-label, multi-center study to evaluate the safety and tolerability of emicizumab in participants with congenital hemophilia A who have documented inhibitors against Factor VIII (FVIII) at…
- Trial name
- STASEY (NCT03191799)
- Testing
- Emicizumab
- Where
- 72 sites in Australia, Belgium and 22 more
- Volunteers
- 195 people
- Sponsor
- Hoffmann-La Roche
Cancer
Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor
RATIONALE: When irradiated lymphocytes from a donor are infused into the patient they may help the patient's immune system kill cancer cells.
- Trial name
- NCT00161187
- Testing
- therapeutic allogeneic lymphocytes
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Ischemic Stroke
Hemodynamic Effects on Cerebral Autoregulation in Acute Stroke
This study investigates if there are hemodynamic alterations in acute stroke that predispose patients to impaired perfusion and regulation of cerebral blood flow.
- Trial name
- NCT02056821
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Henry Ford Health System
HIV Infections
A Third-Party Blinded, Placebo Controlled Comparative Study of AS-101 Administered Intravenously in HIV Positive Patients With Advanced Disease
To compare the effect of AS-101 to that of placebo on clinical efficacy and immunologic function in HIV positive patients with advanced disease.
- Trial name
- NCT00002033
- Testing
- Zidovudine, AS-101
- Where
- 4 sites in Brazil
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
HIV Infection
A Long Term, Safety Study of Apricitabine in HIV-infected Subjects
The study will examine how safe and effective apricitabine is when given long term (as ongoing treatment) to HIV patients who have already completed the AVX-201 trial
- Trial name
- NCT00367952
- Testing
- apricitabine
- Where
- Australia
- Volunteers
- 42 people
- Sponsor
- Avexa
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