Clinical trials: Blood Cell Count
Treatment Failure, HIV or AIDS, CD4 Cell Counts
Effectiveness of Efavirenz-based Regimen in HIV-1-infected Patients With Nevirapine Hypersensitivity
The primary objective of this study is to compare the effectiveness of EFV-based regimens in HIV-1-infected patients who; (1) were previously allergic to NVP and stopped all ARV simultaneously; (2) were previously allergic to NVP…
- Trial name
- NCT01044810
- Testing
- Efavirenz-based regimens
- Where
- Thailand
- Volunteers
- 559 people
- Sponsor
- Bamrasnaradura Infectious Diseases Institute
Breast, Breast Cancer
Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer
The overall purpose of this study is to investigate whether younger subjects report pain with pegfilgrastim (or biosimilar substitution) more often and/or at higher levels (greater intensity) than older subjects.This study will…
- Trial name
- NCT04174742
- Testing
- pegfilgrastim
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- Wake Forest University Health Sciences
HIV Infections
Raltegravir One Thousand Two Hundred vs Darunavir-cb in Immnunosupressed Patients: ROTDIP Study
Multicenter, randomized, open label pilot clinical trial with two parallel arms aimed to compare the efficacy of Raltegravir (RAL) 1200mg QD vs Darunavir/Cobicistat (DRV-cb) 800-150mg QD both in combination with…
- Trial name
- ROTDIP (NCT03842488)
- Testing
- Experimental: RAL QD, Active comparator: DRV/cb
- Volunteers
- 75 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Blood Stem Cell Harvest Failure
Peripheral Blood CD34-positive Cells Enumeration as Predictor of Stem Cell Harvest
Stem cell mobilization procedures after chemotherapy and G-CSf performed at our Institution between 2002 and 2013 were reviewed in order to define prognostic factors for optimal harvest
- Trial name
- NCT02023814
- Volunteers
- 250 people
- Sponsor
- Ospedale Santa Croce-Carle Cuneo
Cancer, Cancer-related Problem/Condition
Home Monitoring of Complete Blood Count Performed by Patients - a Pilot Study on the Implementation Process in South Baltic Countries.
Introduction: The number of diagnosed cancers is systematically increasing every year. Cancer patients need to undergo regular blood tests to monitor safety and eligibility for treatment.
- Conditions
- Cancer, Cancer-related Problem/Condition, Chemotherapy, Chemotherapy-induced Neutropenia
- Trial name
- AMBeR eBlood (NCT06809101)
- Where
- 5 sites in Denmark, Germany and 1 more
- Volunteers
- 265 people
- Sponsor
- Pomeranian Medical University Szczecin
Weight Loss, Exercise
Effects of Exercise and Short Term Rapid Weight Loss on Whole Blood Cells and Lymphocyte Subsets in Highly Trained National Level Wrestlers
Wrestling is a weight-classified sport in which athletes frequently apply rapid weight loss (RWL) strategies prior to competition.
- Trial name
- EX-RWL-Lymphoc (NCT07567937)
- Testing
- Exercise, Rapid Weight Loss
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Preoperative Anxiety, Preoperative Evaluation
Association Between Preoperative Anxiety and Blood Eosinophil Levels
In the studies, the presence of preoperative anxiety has been evaluated and reported with anxiety scales. The presence of anxiety and allergic diseases has also been examined in a limited study with the analysis of neuroendocrine…
- Conditions
- Preoperative Anxiety, Preoperative Evaluation, STAI, Eosinophil Blood Count
- Trial name
- NCT06837415
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Naime Yalçın
Mycobacterium Avium-intracellulare Infection, HIV Infections
A Study to Evaluate the Effects of Azithromycin on MAC Disease Prevention in HIV-Positive Patients
This study is designed to find out whether HIV-positive patients whose immune systems have improved after receiving anti-HIV treatment should take azithromycin to prevent Mycobacterium avium complex (MAC) disease.
- Trial name
- NCT00000947
- Testing
- Azithromycin
- Where
- 19 sites in United States
- Volunteers
- 850 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Pregnancy, Infections in, Covid19
Perinatal Outcomes and Hematologic Parameters in COVID-19 Pregnancies
Complete blood count parameters are routinely evaluated cost-effective markers in diagnosis and clinical follow-up of infectious diseases.There is increasing number of studies to report the course of COVID-19 in pregnancy.
- Trial name
- NCT04515108
- Testing
- Clinical assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
HIV Infections
A Study of Thymic Humoral Factor (THF Gamma 2) in HIV-Infected Patients
To investigate the safety of thymic humoral factor (THF gamma 2), its effect on HIV load based on at least a 75 percent decrease in HIV quantitative PCR RNA copies/ml, and its persistence when administered in combination with an…
- Trial name
- NCT00002435
- Testing
- Thymic Humoral Factor, Zidovudine
- Where
- 10 sites in United States
- Sponsor
- Pharmacia
HIV Infections
The Safety and Effectiveness of BI-RG-587 in HIV-Infected Patients
To assess the safety and tolerance of multiple oral doses of Nevirapine (BI-RG-587). To generate data on the pharmacokinetics and dose proportionality of Nevirapine with multiple dosing.
- Trial name
- NCT00000962
- Testing
- Nevirapine
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Preterm Infant, Early-Onset Neonatal Sepsis
Utility of Placental/Umbilical Cord Blood in Early Onset Neonatal Sepsis in Very Low Birth Weight Infants
This study evaluates the utility of placental/umbilical cord blood (PUCB) to perform the baseline workup testing for EONS in Very Low Birth Weight Infants: CBC (Complete Blood Count) with differential, Immature/Total ratio (I/T…
- Conditions
- Preterm Infant, Early-Onset Neonatal Sepsis, Umbilical Cord
- Trial name
- NCT03694613
- Testing
- Placental/Umbilical Cord Blood sample
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Triple Negative Breast Cancer
Correlation Between TILs and Blood Cell Counts in Triple Negative Breast Cancer Patients
The PERCEPTION study aims to assess the correlation between blood cell counts (Leucocytes, Neutrophils, Lymphocytes, Platelets, NLR (Neutrophil-to-Lymphocyte Ratio) and PLR (Platelet-to-Lymphocyte Ratio)) and Tumor Infiltrating…
- Trial name
- PERCEPTION (NCT04068623)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre Jean Perrin
HIV Infections, Immunological Abnormality
The Role of Probiotics in HIV Patients With Immunological Non-Responder
This study will address HIV patients who are on antiretroviral treatment (ART) and experiencing immunological failure. The cause of immunological failure in HIV patients could be due to several factors such as age, gender…
- Trial name
- PIONIR (NCT03568812)
- Testing
- Rillus®
- Where
- Indonesia
- Volunteers
- 80 people
- Sponsor
- Universitas Indonesia
Acute Myeloid Leukemia in Remission, Lymphoma in Remission
Evaluation of a Donor Testing Kit for the Prediction of AGVHD in Patient Receiving a Peripheral Blood Stem Cell Allograft
The aim is to validate an in vitro diagnosis medical device to predict grade II to IV aGVHD after a cell graft
- Conditions
- Acute Myeloid Leukemia in Remission, Lymphoma in Remission, Non-progressive Myeloproliferative Syndrome, Myelodysplasia With Stable Blasts is Cell Number and < 10% of Blastocysts
- Trial name
- Predictor2 (NCT03887156)
- Testing
- Ex vivo capacities of CD4neg INkT expansion of the peripheral blood donor with the Predictor test
- Where
- 22 sites in Belgium, France and 1 more
- Volunteers
- 227 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV Infections
A Study to Evaluate the Effects of Interleukin-12 (rhIL-12) in HIV-Positive Patients With CD4 Cell Counts Less Than 50 Cells/mm3 or 300-500 Cells/mm3
The purpose of this study is to determine the tolerance and effectiveness of rhIL-12 in HIV-positive patients with CD4 cell counts less than 50 cells/mm3 versus 300-500 cells/mm3.
- Trial name
- NCT00000857
- Testing
- Interleukin-12
- Where
- 16 sites in United States
- Volunteers
- 65 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Myelogenous Leukemia
Nilotinib vs Imatinib in Adult Patients With Philadelphia (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP)
In this study, the efficacy and safety of nilotinib 400 mg twice daily, will be compared with imatinib 400 mg twice daily in patients with a suboptimal response to imatinib for their Philadelphia chromosome-positive (Ph+) Chronic…
- Trial name
- ENEST (NCT00519090)
- Testing
- Imatinib, Nilotinib (AMN107)
- Where
- 80 sites in United States, Australia and 8 more
- Volunteers
- 6 people
- Sponsor
- Novartis Pharmaceuticals
Anemia, Chronic Renal Insufficiency
A Study to Evaluate PROCRIT (Epoetin Alfa) for Maintenance Phase Treatment of Patients With Anemia Due to Chronic Kidney Disease (PROMPT)
The purpose of this study is to evaluate the effectiveness and safety of less frequent dosing of PROCRIT (Epoetin alfa) in patients with anemia due to Chronic Kidney Disease (CKD) as assessed by hemoglobin maintenance, adverse…
- Trial name
- NCT00307814
- Testing
- Epoetin Alfa
- Volunteers
- 519 people
- Sponsor
- Ortho Biotech Products, L.P.
Hepatitis B
Hepatitis B Vaccination in HIV-infected Adults With Low CD4 Cell Counts
This study aimed to evaluate the efficacy of different hepatitis B vaccination regimens in HIV-infected adults with low CD4 cell count in northern Thailand.
- Trial name
- NCT02732054
- Testing
- Recombinant Hepatitis B vaccine [(CIGB) La Habana, Cuba]
- Where
- Thailand
- Volunteers
- 16 people
- Sponsor
- Chiang Mai University
HIV Infections
Effect of Interleukin-2 on HIV Treatment Interruption
Interleukin-2 (IL-2) helps the body make infection-fighting white blood cells, including CD4 and CD8 T cells. One HIV treatment strategy is planned treatment interruption (stopping anti-HIV drugs when CD4 count and level of virus…
- Trial name
- NCT00015704
- Testing
- Aldesleukin
- Where
- 17 sites in United States
- Volunteers
- 80 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)