Clinical trials: Blood Circulation
Rotator Cuff Related Shoulder Pain
Exercise-induced Hypoalgesia Effects of Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain
This study aims to compare the effects of blood flow restricted (BFR) exercise and to examine the differences between various BFR protocols on acute pain reduction in individuals with rotator cuff-related shoulder pain, as well…
- Trial name
- NCT07232511
- Testing
- Resistance exercise with low AOP, Resistance exercise with moderate BFR, Resistance exercise with high BFR
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Valencia
Heart-Assist Devices, Heart Failure
Individual Blood Pressure Optimization Based on Cerebral Autoregulation After Implantation of Continuous-flow LVAD
This study will collect retrospective and prospective clinical data regarding the Principal Investigator's patient population to allow for data analysis seeking basic trends and to prepare academic reports, including journal…
- Trial name
- NIRS (NCT03093012)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Baylor College of Medicine
Cerebral Arterial Diseases
Modulation of Brain Blood Flow Using Dichoptic Visual and Auditory Stimulation
Modulation of brain blood flow using dichoptic Visual and Auditory stimulation using REVIVIEW system will be evaluated.
- Trial name
- NCT03632564
- Testing
- REVIVIEW dichoptic audio-visual stimulation
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Visior Technologies Ltd.
Abnormal Vascular Flow
Effects of Milking the Umbilical Cord on Systemic Blood Flow
Premature babies are at risk for bleeding in their brains, which can result in developmental delays or other neurological problems such as cerebral palsy.
- Trial name
- NCT01434732
- Testing
- Umbilical Cord Milking, Immediate Cord Clamping
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Sharp HealthCare
Cerebrovascular Function, Cognition
Oral Ketone Monoester Supplementation and Resting-state Brain Connectivity
People who report subjective memory complaints have a greater risk of developing dementia. Memory issues may be an early warning sign of dysfunctional cerebral glucose metabolism and cerebral blood flow.
- Trial name
- NCT05992571
- Testing
- β-OHB
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Type 2 Diabetes
The Effect of Welchol on Glucose Metabolism in Type 2 Diabetics
The goal of this study was to determine the metabolic mechanism for a certain type medication's ability to lower blood sugar after a meal in Type 2 Diabetics, in order to develop a better understanding of it's potential role in…
- Trial name
- NCT00951899
- Testing
- Colesevelam, Diet, Metformin
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Mayo Clinic
Regional Cerebral Blood Flow, Mild Cognitive Impairment
Effects of Photobiomodulation on Changes in Cognitive Function and rCBF in MCI
This pilot study has two goals. The first is to see if the cognitive improves when VA and CA are stimulated in MCI patients, and the second is to do an explanatory data analysis to see if that improves cognitive in relation to…
- Conditions
- Regional Cerebral Blood Flow, Mild Cognitive Impairment, Cognitive Function
- Trial name
- NCT04721093
- Testing
- Photobiomodulation device
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- Pusan National University Yangsan Hospital
Dry Needling, Shoulder Pain
Dry Needling and Shoulder Muscle Blood Flow, Motions, and Pain Sensitivity
Shoulder pain is one of the most common reasons people consult with their primary health care provider, and 40-50% of these patients with shoulder pain continued to complain of persistent symptoms after 6 to 12 months.
- Trial name
- NCT05467098
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Healthy
The Effect of Lopinavir/Ritonavir on Endothelial Function
This study will examine how the anti-HIV protease inhibitor lopinavir/ritonavir (Kaletra® (Registered Trademark)) affects the function of the endothelium (lining of the arteries).
- Trial name
- NCT00076414
- Testing
- Acetylcholine, L-NMMA
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Peripheral Arterial Disease
Acute Effects of Leg Heating on Skeletal Muscle Blood Flow
The purpose of this study is to apply local heat to the legs, thighs and buttocks of patients with peripheral arterial disease and use PET/CT imaging with an injectable stable radiotracer to study direct measurement of blood flow…
- Trial name
- NCT03763357
- Testing
- Heat Therapy (HT)
- Sponsor
- Indiana University
Oral Glucose Tolerance Test, High Fat Tolerance Test
Effects of Fluid Milk in Attenuating Hyperglycemia and Hypertriglyceridemia After Meal
Epidemiological studies indicate that risk of type 2 diabetes is lower when milk is consumed in the regular diet. Milk products are unique in that they produce high insulin response despite their low glycemic index.
- Trial name
- NCT02894112
- Testing
- non-fat milk, carbohydrate control beverage, caloric control beverage
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Healthy
Evaluating Q-Collar Effects on Brain Blood Flow Control During Exercise
The goal of this clinical trial is to learn how the FDA-cleared Q-Collar device affects brain blood flow regulation during rest and exercise in healthy adults. The main questions this study aims to answer are: 1.
- Trial name
- NCT06826781
- Testing
- Q30 Q-Collar, Not wearing Q-Collar
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Microcirculation
The Effect of Photobiomodulation on Microvascular Blood Flow: The Role of Wavelength and Skin Temperature
The objective of this study is to assess peripheral microcirculatory hemodynamic responses to photobiomodulation in participants with normal circulation and with functional peripheral vasoconstriction, using noninvasive…
- Trial name
- PBM&MBF01 (NCT07338695)
- Testing
- Photobiomodulation - Blue Wavelength, Photobiomodulation - Near Infrared
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Afeka, The Tel-Aviv Academic College of Engineering
Premature Birth, Extremely Low Birth Weight
DCS Study in Extremely Premature Newborns
The researchers are attempting to improve the cerebral monitoring of extremely low gestational age (ELGA) infants, such that in the future, real-time monitoring will be possible, to aid clinicians in management of these infants.
- Conditions
- Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
- Trial name
- NCT04367181
- Testing
- Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Maria Angela Franceschini
Arterial Hypertension, Blood Pressure, High
Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension
To evaluate whether in patients with initially poorly-controlled arterial hypertension, structural and functional differences in the retina and choroid remain after achieving a well-controlled blood pressure.
- Trial name
- NCT06098300
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Thoracic Surgery, Cardiopulmonary Bypass
Variations of the Lung Compliance During Extracorporeal Circulation and Post Operative Pulmonary Complications
the decrease in thoracopulmonary compliance after cardiac surgery is well known . The investigators hypothesize that the major factor determining pulmonary outcome after cardiac surgery is the alteration of pulmonary compliance…
- Trial name
- COMPLI (NCT02654600)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Fluid Overload, Water Electrolyte Imbalance
The Effect of Crystalloids and Colloids on Visceral Blood Flow
Patients often require fluid replacement during and after an operation. This is usually given through veins in the arm using an intravenous cannula and doctors have traditionally used fluid containing sodium chloride (saline).
- Conditions
- Fluid Overload, Water Electrolyte Imbalance, Acid Base Imbalance
- Trial name
- NCT01087853
- Testing
- Crystalloid, Colloid
- Where
- United Kingdom
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Aneurysm, AVM
Intraoperative Laser Speckle Contrast Imaging to Assess Blood Flow During Neurosurgery
Cerebral blood flow (CBF) is of paramount importance to human brain function, as the brain relies on a continuous blood supply to meet its energy needs.
- Conditions
- Aneurysm, AVM, Dural Arteriovenous Fistula, Glioma
- Trial name
- LSCI-NSURG (NCT05028400)
- Testing
- Laser speckle contrast imaging (LSCI)
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Mean Blur Ratio
Isometric Exercise in NTG
Glaucoma is the second leading cause of blindness worldwide. Literature shows increasing evidence that dysfunction of ocular microcirculation in the optic nerve influences the progression of glaucoma.
- Trial name
- NCT03921372
- Testing
- Isometric exercise
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augenabteilung Allgemeines Krankenhaus Linz
PCOS
PCOS and Brain Health
The purpose of this study is to determine how polycystic ovary syndrome (PCOS) impacts overall brain health, such as cerebral blood flow (CBF), brain structure and connectivity, and cognitive performance.
- Trial name
- NCT07727512
- Testing
- MRI Visit, Laboratory Visit
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison