Clinical trials: Blood Flow
Autonomic Dysreflexia
Fesoterodine for Amelioration of Autonomic Dysreflexia (AD) Following Spinal Cord Injury (SCI)
This study will be investigating the effects of fesoterodine on autonomic dysreflexia (AD) in patients with spinal cord injuries (SCI).
- Trial name
- NCT02676154
- Testing
- Fesoterodine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of British Columbia
Asymptomatic Condition
Instrument Assisted Soft Tissue Mobilization Effect on Blood Flow
This study is designed to evaluate the short term change in blood flow in the superficial human tissue layers after the application of 3 min Graston instrumented assisted soft tissue mobilization on the plantar aspect of the foot…
- Trial name
- NCT04785079
- Testing
- Graston Instrument assisted Soft tissue Mobilization
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Retinal Blood Flow
Measurement of Total Retinal Blood Flow and Oxygen Extraction in Patients With Diabetes and Healthy Subjects
The prevalence of diabetes and diabetes-associated complications is still increasing. Several major long-term complications of diabetes such as cardiovascular disease, chronic renal failure, diabetic retinopathy and others relate…
- Trial name
- NCT03552562
- Testing
- Fourier Domain Color Doppler Optical Coherence Tomography (FDOCT)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Shoulder Injury
Blood Flow Restriction Therapy Following Acute Shoulder Injury Patients
Atrophy and weakness of the shoulder are a common problem following treatment of a number of shoulder and elbow pathologies. Even with relatively short periods of reduced activity, the magnitude of muscle loss can be quite…
- Trial name
- BFR (NCT06223373)
- Testing
- Blood Flow Restriction
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer, Breast Abnormalities
Evaluate Breast Masses Using a New Method of Ultrasound Contrast to Detect Abnormal Blood Flow in Breasts
The purpose of this study is to determine if breast imaging with ultrasound can be improved by using 1) a ultrasound attachment with two transducers and 2) a contrast agent.
- Trial name
- NCT00722683
- Testing
- Ultrasound Imaging with Contrast
- Where
- United States
- Sponsor
- University of Michigan
Osteoarthritis (OA) of the Knee
Impact of Blood-Flow-Restriction Prehabilitation on Pre- and Postoperative Rehabilitation After Total Knee Arthroplasty
Degenerative and traumatic diseases of the musculoskeletal system lead to increased immobility of a patient, which in turn results in muscle atrophy.
- Trial name
- NCT06964022
- Testing
- BFR
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- University Hospital, Bonn
Peripheral Arterial Disease, Osteopathy in Diseases Classified Elsewhere
The Effect Of Osteopathic Manual Therapy On Arterial Circulation In Patients With Peripheral Arterial Disease
Peripheral artery disease (PAD) is a chronic atherosclerotic process that causes narrowing of peripheral arterial vessels in the lower extremities.
- Trial name
- NCT05837442
- Testing
- Osteopathic Manual Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Kırıkkale University
Ischaemic Stroke
The RETRAIN Trial Phase 2
Ischaemic strokes, caused by a disruption in the brain's blood supply, are the second leading cause of death and disability in the United Kingdom.
- Trial name
- RETRAIN 2 (NCT07197996)
- Testing
- Intermittent Pneumatic Compression, geko® T3
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- Firstkind Ltd
Prostate Cancer
Study to Monitor the Effects of Androgen Suppression Treatment on the Heart
Suppression of effects of androgens with male sex hormones, androgen suppression treatment (AST), has been known to reduce deaths and prolong life in advanced prostate cancer.
- Trial name
- AST (NCT01230905)
- Testing
- PET scan and ultrasound
- Where
- Canada
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Coronary Vasospasm
Effect of Glucose on Ocular Blood Flow
The primary objective is to assess the effect of glucose on retinal vascular diameter in otherwise healthy vasospastic subjects compared to non-vasospastic controls.
- Trial name
- NCT00350129
- Where
- Switzerland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection
Central Venous Catheter-related Complications in Patients Under Anticancer Treatment
Oncology and hemotology patients under anticancer treatments are exposed to increased risks of central venous catheter-related complications due to the underlying cancer and its treament.
- Conditions
- Central Venous Catheter Thrombosis, Central Venous Catheter Related Bloodstream Infection, Solid Tumor, Hematologic Malignancy
- Trial name
- KTcCHO (NCT05455866)
- Testing
- central venous catheter
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Alpes Leman
Hypertrophy
High Intensity Resistance Training Combined With Blood Flow Restricted Exercise in Elite Handball Players
Purpose of the study is: to investigate the effects of 8 weeks intervention of high intensity resistance training(HIRT) combined with Blood Flow Restricted Exercise (BFRE) compared to high intensity resistance training alone.
- Trial name
- NCT04750694
- Testing
- Resistance training
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Department of Public Health, Denmark
Brain Insulin Sensitivity, Brain Vascular Function
Effects of Ketone Monoesters on Brain Function
Disturbances in brain insulin-sensitivity are not only observed in obesity and type 2 diabetes (T2D), but also during brain aging and in dementia.
- Conditions
- Brain Insulin Sensitivity, Brain Vascular Function, Cerebral Blood Flow, Cognitive Performance
- Trial name
- NCT06395051
- Testing
- Ketone Monoester
- Where
- Netherlands
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Physical Activity, Aging
Independent Walking for Brain Health
Physical activity interventions with older adults can improve brain health; however most interventions have been performed in gym-like settings that reach a small sector of the senior population.
- Trial name
- NCT03058146
- Testing
- Mobile Health Walking Condition, Healthy Aging Education Condition
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pre-diabetes, Type 2 Diabetes
Mechanisms of Fatigability With Diabetes
Pre-diabetes (Pre-D) is a precursor to type 2 diabetes (T2D) and characterized by increased exercise fatigability of lower limb muscles, that can impede exercise performance.
- Trial name
- NCT04442451
- Testing
- Control Exercise, Blood Flow Restriction Exercise
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Aging, Arterial Stiffness
Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
This study investigates the effect of dietary inorganic nitrate supplementation on 1) large elastic artery stiffness and hemodynamics and 2) cerebrovascular function in middle-aged and older adults.
- Conditions
- Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension
- Trial name
- INCA (NCT03617302)
- Testing
- Experimental: Nitrate-containing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce, PhD
Pediatric Cardiac Surgery, Complication of Extracorporeal Circulation
A Pilot Study Comparing Anti-Inflammatory Effects Of TXA Versus EACA In Pediatric Congenital Heart Surgery
The purpose of this study is to compare anti-inflammatory effects of two anti-fibrinolytic drugs (Tranexamic acid versus Epsilon-aminocaproic acid) in pediatric patients undergoing pediatric cardiac surgery.
- Trial name
- TXAEACA (NCT02656472)
- Testing
- Tranexamic acid, Epsilon Aminocaproic Acid
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Nicotine Dependence, Cigarettes
Acute Oral Effects of Heated Tobacco Products
Heated tobacco products (HTP) are devices which heat, but not burn tobacco. They do not produce cigarette smoke but rather an aerosol. HTPs are marketed as less harmful alternatives to smoking.
- Trial name
- NCT05538702
- Testing
- IQOS 3.0 DOU with bland taste unit (Heated Tobacco Product), IQOS 3.0 DUO with menthol taste unit (Heated Tobacco Product), Marlboro Gold (Conventional cigarette)
- Where
- Hungary
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Diabetic Neuropathy Peripheral
Effects of BFRT on Glycemic Control, Nerve Conduction, Functional Outcomes and QOL in Individuals With Type 2 Diabetes
Diabetic peripheral neuropathy is one of the most prevalent complications of Type 2 Diabetes Mellitus. Peripheral neuropathy is caused by unavailability of glucose in cells and low metabolism.
- Trial name
- NCT07763795
- Testing
- BFR with low resistance high repetition exercises, low resistance high repetition exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Superior University
AML, Acute Myelogenous Leukemia
Diagnosis and Treatment of Periodontal Disease in Patients With AML
This is a phase 2 randomized controlled trial of pre-chemotherapy periodontal deep cleaning in Acute Myelogenous Leukemia (AML) patients with asymptomatic periodontitis.
- Trial name
- NCT04530695
- Testing
- Scaling and Root Planing
- Sponsor
- Masonic Cancer Center, University of Minnesota