Clinical trials: Blood Glucose, High
Metabolic Syndrome
Canola Oil, Fibre and DHA Enhanced Clinical Trial
The purpose of this study is to examine the effects of consumption of a novel food supplement consisting of Canola Oil, Fibre and DHA, containing the most effective food bioactives, including n-3 fatty acid enriched dietary oil…
- Trial name
- NCT02091583
- Testing
- Butter, sunflower and safflower oil, High Oleic Canola Oil and DHA (HOCO-DHA), Barley beta-glucan
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Diabetes, Gestational
Effect of Carbohydrate Distribution on Blood Glucose in Women With Gestational Diabetes Mellitus (GDM)
This study aims to investigate whether high-morning carbohydrate intake (HMK) compared with low-morning carbohydrate intake (LMK) affects glycemic variability in GDM patients based on Continuous glucose monitoring (CGM).
- Trial name
- NCT03835208
- Testing
- High/low carbohydrate distribution
- Where
- 2 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- University of Aarhus
Vascular Diseases, Hypercholesterolemia
The Effect of Plant Sterols on the Blood Lipid Profile of Subjects With and at High Risk of Type 2 Diabetes Mellitus
Double-blind, randomised, placebo-controlled, parallel group study with two intervention arms. The study will be conducted in 150 subjects and the primary objective is to show a fasting LDL-cholesterol and triglyceride lowering…
- Conditions
- Vascular Diseases, Hypercholesterolemia, Diabetes Mellitus
- Trial name
- NCT02288585
- Testing
- Plant sterols
- Where
- 2 sites in Australia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study A)
To assess the effectiveness of reporting statin adherence patterns to a Medication Adherence Partner (MAP) in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02018809
- Testing
- Medication Adherence Partner, Electronic pill bottle
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pennsylvania
Type 2 Diabetes Mellitus (T2DM)
Study of Efficacy and Safety of Vildagliptin as add-on Insulin Therapy in T2DM Patients
The purpose of this study was to assess the efficacy and safety of vildagliptin 50 mg bid add-on therapy to improve overall glycemic control in patients with T2DM inadequately controlled by insulin, with or without concomitant…
- Trial name
- NCT02002221
- Testing
- Vildagliptin (LAF237), Insulin, Metformin
- Where
- 31 sites in Japan
- Volunteers
- 156 people
- Sponsor
- Novartis Pharmaceuticals
Cardiovascular Risk Factor, Pre Diabetes
Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Background: The rising levels of physical inactivity in the Eastern Mediterranean region (43.2%) and in the United Arab Emirates (38%) compared with the global levels of physical inactivity (31.2%) is alarming (6,15).
- Conditions
- Cardiovascular Risk Factor, Pre Diabetes, High Blood Pressure, Elevated LDL Cholesterol
- Trial name
- NCT04403789
- Testing
- Exercise Time, Supervised Group Exercise
- Where
- United Arab Emirates
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Dyslipidemias, Metabolic Syndrome
Effects of HIIT on Metabolic Syndrome
The project aims to find out the differences between two different types of structured training interventions have on the lipid profile of persons with diagnosed dyslipidemia. Each training intervention will last for 12 weeks.
- Conditions
- Dyslipidemias, Metabolic Syndrome, Sedentary Behavior, Obesity
- Trial name
- NCT04133129
- Testing
- Low Volume-High Intensity Interval Training, Moderate Intensity Continuous Training
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Coventry University
Type1diabetes
Fasted Exercise in People With Type 1 Diabetes
This study aims to compare the effect of a bout of high-intensity interval training (HIT) with a bout of moderate-intensity continuous training (MICT) on glucose concentrations over the subsequent 24h period.
- Trial name
- NCT03544684
- Testing
- Effects of the type of exercise on blood glucose concentrations
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Critical Illness, Hyperglycemia
Study of High Blood Sugars and Insulin in Hospitalized, Critically Ill Children
BACKGROUND AND PURPOSE Critical illness hyperglycemia (CIH) - elevated blood glucose in the critically ill patient population - has gained much interest among health care providers over the past several years.
- Trial name
- CIH (NCT00487006)
- Testing
- Serum Lab testing
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Children's Healthcare of Atlanta
Diabetes Mellitus, Type 2
A Randomized, Double-Blind, Comparator- and Placebo-Controlled, Multiple-Dose Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of MSDC-0602 in Type 2 Diabetic Patients
The purpose of this study is to assess the safety and tolerability of MSDC-0602 and to evaluate the reduction in fasting plasma glucose in patients with Type 2 diabetes.
- Trial name
- NCT01280695
- Testing
- MSDC-0602 100 mg, MSDC-0602 250 mg, Pioglitazone
- Where
- 14 sites in United States
- Volunteers
- 129 people
- Sponsor
- Metabolic Solutions Development Company
Diabetes Mellitus, High Blood Pressure
Magnesium and Metabolic Syndrome
Objective : to test the BP lowering-effect of oral magnesium supplementation, as magnesium chloride (MgCl2) solution, 2.5 g daily, in uncomplicated hypertensive type 2 diabetic subjects with decreased serum magnesium levels…
- Conditions
- Diabetes Mellitus, High Blood Pressure, Hypomagnesemia
- Trial name
- NCT00603499
- Testing
- Magnesium chloride
- Where
- Mexico
- Volunteers
- 85 people
- Sponsor
- Instituto Mexicano del Seguro Social
High Risk Hypertensive Patients
Study to Improve Quality of Care and Patient Health in the Field of Cardiovascular Risk Factors in General Practice
Observational studies performed in France and abroad in hypertensive patients at high cardiovascular risk have shown a wide gap between the therapeutic targets reached in ambulatory patients and those set by guidelines.
- Trial name
- ESCAPE (NCT00348855)
- Testing
- Cardiovascular drugs strategies, Compliance, Exercise
- Where
- 2 sites in France
- Volunteers
- 1,836 people
- Sponsor
- Collège National des Généralistes Enseignants
Overweight or Obesity
Multicenter Trial Investigating Performance and Safety of the Medical Device SiPore21®
The present clinical investigation is a randomized, double-blinded, placebo-controlled, multicenter international trial, planned to be conducted in Poland, Romania and Slovakia.
- Trial name
- SHINE (NCT06087822)
- Testing
- IMD SiPore21®
- Where
- 27 sites in Poland, Romania and 1 more
- Volunteers
- 318 people
- Sponsor
- Sigrid Therapeutics AB
Type 2 Diabetes, High Blood Pressure
Polypill for Prevention of Cardiomyopathy
This study will investigate the utility of a polypill-based strategy for patients with type 2 diabetes mellitus and high risk of heart failure (HF), as assessed via the WATCH-DM risk score.
- Trial name
- PolyPreventHF (NCT06143566)
- Testing
- Polypill, Combined prescription of the individual medications
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Texas Southwestern Medical Center
Type 2 Diabetes
The Effects of High and Low GI Breakfasts on Cognitive Performance in Adults With Type 2 Diabetes
Consumption of a low glycemic index (GI) diet has been shown to improve glycaemic control in type 2 diabetics(Brand-Miller et al., 2003; Jenkins et al., 2008).
- Trial name
- NCT01047813
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Blood Glucose, Postprandial
Effect of Escalating Doses of a Novel Viscous Polysaccharide on Postprandial Glycemia
To determine palatability and extent to which escalating doses of a novel highly viscous polysaccharide [NVP] reduces postprandial glycemia when added to a liquid and a solid meal.
- Trial name
- NCT00801814
- Testing
- PolyGlycopleX (PGX), PolyGlycopleX (PG), PolyGlycopleX
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Glycemic Index Laboratories, Inc
Blood Sugar; High, Blood Pressure
Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures
The average adult in the US consumes over 1/3 of a cup of sugar each day, or nearly 300 calories worth, with the primary sources being from beverages, desserts and sweet snacks, candy, additions to beverages, and foods such as…
- Conditions
- Blood Sugar; High, Blood Pressure, Dietary Habits
- Trial name
- NCT05658757
- Testing
- Regular sweetened commercial foods, Allulose sweetened commercial foods, Whole and minimally processed and sweetened foods
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Atherosclerosis, High Blood Pressure
Latinos Understanding the Need for Adherence
The Latino population in the United States is increasing in size; is diverse in culture, backgrounds and countries of origin; is experiencing unique influences from social and behavioral acculturation to the U.S.; is reported…
- Conditions
- Atherosclerosis, High Blood Pressure, Type 2 Diabetes Mellitus, Heart Disease
- Trial name
- LUNA (NCT02955238)
- Testing
- Special Intervention
- Where
- United States
- Volunteers
- 587 people
- Sponsor
- San Diego State University
Metabolic Syndrome
Effect of a Grape Seed Extract (GSE) on Insulin Resistance
In people with the metabolic syndrome, the investigators hypothesize that administration of a single 300 mg dose of a grape seed extract (GSE) will reduce insulin resistance (how well cells in the body can take up and use…
- Trial name
- NCT01889368
- Testing
- Grape Seed Extract
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Davis
Blood Glucose, High, Oral Hypoglycaemic Overdose
Impact of Oral Glucose Tolerance Test on Extent of Hemoglobin Glycation
The glycation extent of human hemoglobin is under control of the Maillard reaction, a chemical interaction between an amino acide and a reducing sugar.
- Trial name
- HbA1c (NCT04018430)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Urs E. Nydegger