Clinical trials: Blood Insulin
Multiple Myeloma
Study of AVE1642 Anti-IGF1R Monoclonal Antibody in Patients With Advanced Multiple Myeloma
Primary Objectives: Study Part 1: Determine the selected dose of AVE1642 administered every 3 weeks based on pharmacokinetic (PK) (Clearance of AVE1642), pharmacodynamic (PD) (insulin-like growth factor 1 [IGF-1] serum level)…
- Trial name
- NCT01233895
- Testing
- AVE1642, Velcade
- Where
- 4 sites in France, Italy
- Volunteers
- 26 people
- Sponsor
- Sanofi
Cardiac Surgery Patients, Blood Glucose
Glucose Control by eMPC Algorithm in Peri- and Postoperative Period in Cardiac Surgery Patients
Randomized controlled trial to compare blood glucose control by the model predictive control algorithm with variable sampling rate (eMPC) with routine glucose management protocol (RMP) in peri- and postoperative period in cardiac…
- Trial name
- NCT00444171
- Testing
- insulin infusion rate controled by computer algorithm, insulin infusion rate guided by in-house glucose management protocol
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Charles University, Czech Republic
PreDiabetes
Study: Diet and Exercise Study to Improve Brain Blood Flow: Blood Flow Improvement Trial
Project Summary Metabolic syndrome (MetS) is associated with the development of diabetes and cardiovascular disease; however it is also linked with cognitive decline and dementia.
- Trial name
- BFIT (NCT03117829)
- Testing
- Diet and Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Sitosterolemia
The Effect of Dietary Sitosterol on Blood Sugar and Cholesterol
This study will determine if dietary supplements of sitosterol (a plant cholesterol commonly found in vegetables) can modify blood sugar and cholesterol levels and reduce the stiffness of the blood vessels in people with an…
- Trial name
- NCT00531128
- Testing
- High/Low Sitosterol
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Blood Pressure
The Acute Effect of Mango Intake (Mangifera Indica L.) on Blood Pressure and Blood Glucose
In the current proposal the investigators seek to evaluate the acute effects of mango intake on blood pressure, blood glucose and insulin in postmenopausal women between 50 and 70 years old.
- Trial name
- NCT04057495
- Testing
- further fasting, white bread consumption, mango consumption
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
CGM, Intensive Care (ICU)
Evaluate the Performance of the Dexcom G7 Continuous Glucose Monitoring (CGM) System in Critically Ill Patients Undergoing Major Abdominal Surgery and Solid Organ Transplantation Which Require Blood Glucose Monitoring for Intensive Insulin Therapy.
Main objective: The goal is to to determine the accuracy of Dexcom G7 Continuous glucose monitor system in critically ill patients, undergoing major abdominal surgery and solid organ transplantation, in the intensive care unit.
- Conditions
- CGM, Intensive Care (ICU), Liver Transplant Surgery, Solid Organ Transplantation
- Trial name
- DREAM-ICU (NCT07611721)
- Testing
- Continuous glucose monitor
- Where
- Czechia
- Volunteers
- 62 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Type 1 Diabetes
Effects of Acipimox on Insulin Action, Vascular Function, and Muscle Function in Type 1 Diabetes
Insulin resistance (IR) is an important contributor to increased cardiovascular disease risk in type 1 diabetes (T1D). Non-esterified fatty acid elevation is a significant contributor to IR in T1D and may be a target of…
- Trial name
- AcT1 (NCT01816165)
- Testing
- Acipimox
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Metabolic Syndromes, HIV Infection
Pilot Study of Metabolic Syndromes and HIV Infections in Indian Tibetans
Kaohsiung Medical University Chung-Ho Memorial Hospital will provide a long-term free medical service in Indian Tibetans since July 2010.
- Trial name
- NCT01261221
- Where
- Taiwan
- Volunteers
- 137 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Metabolic Syndrome (MetS), Hypertension (HTN)
Metabolic Surgery for Metabolic Syndrome
This study is designed to understand how bariatric surgery affects patients with metabolic syndrome over both the short and long term.
- Conditions
- Metabolic Syndrome (MetS), Hypertension (HTN), Obesity, T2
- Trial name
- NCT07183137
- Where
- 3 sites in China
- Volunteers
- 1,581 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Diabetes, Diabetes Mellitus, Type 2
Effect of Two Different Fasting Blood Glucose Targets on Glucose Control in Patients With Type 2 Diabetes Using Insulin Detemir Once Daily
This trial is conducted in the United States of America. The aim of this trial is to explore how different fasting blood glucose targets affect glucose control in patients with type 2 diabetes, when patients are empowered to do…
- Trial name
- TITRATE™ (NCT00634842)
- Testing
- insulin detemir
- Where
- 69 sites in United States, Puerto Rico
- Volunteers
- 244 people
- Sponsor
- Novo Nordisk A/S
Faba Bean, Post-prandial Blood Glucose
Effects of Faba Bean Fractions as Ingredients in Novel Food Products on Glycemia, Appetite and Metabolic Control
To describe the effect and mechanisms of action faba bean powder and fractions (protein, starch and fiber) on glucose and insulin homeostasis, food intake, satiety and metabolic regulation in young adults (18 to 30 years).
- Conditions
- Faba Bean, Post-prandial Blood Glucose, Appetite, Satiety Hormones
- Trial name
- NCT02666586
- Testing
- Faba bean powder smoothie, Faba bean protein concentrate smoothie, Faba bean starch smoothie
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Diseases, Endothelial Dysfunction
Impact of Consuming Plant Sterols on Endothelial Function and Blood Pressure
The purpose of the research is to assess the impact of co-consuming plant sterols-enriched food product as part of a healthy eating pattern diet on endothelial function (brachial artery FMD, vasodilation-related and…
- Conditions
- Cardiovascular Diseases, Endothelial Dysfunction, Metabolic Syndrome, Diet Modification
- Trial name
- NCT03723330
- Testing
- plant sterols, healthy diet
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Menopausal Syndrome
Nanoparticulate Versus Micronized Steroids Delivery for Transdermal Hormone Replacement Therapy
The study aims to asses the effects of micronized (MIC) and nanoparticulate (NANO) transdermal hormone therapy (THT) on blood pressure, ultra-sensitive C-reactive protein (CRP), and cardiovascular risk factors in postmenopausal…
- Trial name
- Nanoparticle (NCT02467673)
- Testing
- Micronized estradiol + progesterone, Nanoparticulate estradiol + progesterone
- Where
- 3 sites in Brazil
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University Potiguar
Blood Pressure
The Effect of Eating Frequency on Blood Pressure
The primary purpose of this study is to identify the effect of meal frequency on blood pressure (BP) levels of individuals.
- Trial name
- NCT01640015
- Testing
- dietary intervention
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Imperial College London
Obesity, Hyperglycemia
The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass
Obesity is a major problem worldwide, and it is related to abnormalities in glucose and lipid metabolism. The purpose of this study is to investigate the effect of a dietary supplement containing probiotic (Bifidobacterium…
- Conditions
- Obesity, Hyperglycemia, Insulin Resistance
- Trial name
- MetSProb (NCT01978691)
- Testing
- Bifidobacterium animalis ssp. lactis 420, Polydextrose
- Where
- 4 sites in Finland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Danisco
Metabolic Syndrome
Effects of Yoga on Metabolic Syndrome
Metabolic syndrome (MetS) is a clustering of cardiovascular risk factors characterizing central obesity, insulin resistance, dyslipidemia and high blood pressure.
- Trial name
- NCT02140203
- Testing
- Yoga Training
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Angus Yu
HIV Infections, Lipodystrophy
Metformin and Rosiglitazone, Alone or in Combination, in HIV-Infected Patients With Insulin and Fat Abnormalities
The purpose of this study is to see whether metformin alone, rosiglitazone alone, or metformin and rosiglitazone together will lower insulin levels in the blood and decrease fat in the abdomen or other parts of the body.
- Conditions
- HIV Infections, Lipodystrophy, Hyperinsulinemia
- Trial name
- NCT00015691
- Testing
- Metformin hydrochloride, Rosiglitazone maleate
- Where
- 34 sites in United States
- Volunteers
- 105 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Diabetes Mellitus, Type 1
Feasibility Study of the Effect of Intra-Dermal Insulin Injection on Blood Glucose Levels After Eating
This study is to determine the effect of intra-dermal (ID) administration of regular and of rapid-acting insulin, before eating, on blood glucose levels for several hours after a standard meal (a mixed, liquid meal).
- Trial name
- NCT00553488
- Testing
- Regular insulin (Humulin), Insulin lispro (Humalog)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Becton, Dickinson and Company
Grain-Like Products, Postprandial Glucose
Postprandial Glucose, Insulin and Subjective Saturation Response in Healthy Individuals
This study is a pioneering study in which the effect of the consumption of cakes produced with the addition of cereal-like products such as chia and flax seeds, which have high soluble fiber content, on blood glucose and insulin…
- Conditions
- Grain-Like Products, Postprandial Glucose, Plasma Insulin, Subjective Saturation Response
- Trial name
- NCT05358561
- Testing
- Flaxseed and Chia
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toros University
HIV Infection, Hepatitis C
Improving Fibrosis Outcomes With Metformin
This study will evaluate the role of Metformin on liver fibrosis in HCV-HIV co-infected and HCV mono-infected patients with insulin resistance receiving DAA HCV treatment.
- Trial name
- NCT02306070
- Testing
- Metformin, No metformin treatment
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute