Clinical trials: Blood Loss,
Trauma Associated Hemorrhage
Prehospital Transfusion Outcomes in Traumatic Hemorrhage: a Prospective Cohort Study
Traumatic injuries can cause severe bleeding, which causes a lot of deaths worldwide that could be prevented. Starting treatment as early as possible has been shown to improve survival, which makes fast care very important.
- Trial name
- PRONTO (NCT07883252)
- Where
- Netherlands
- Volunteers
- 750 people
- Sponsor
- Erasmus Medical Center
Hematoma
The 2-stage Approach for Reducing Posterior Wall Puncture During the Internal Jugular Vein Catheterization
To evaluate the effect of a 2-stage approach to the internal jugular vein when performing a central venous catheterization compared to the traditional one stage approach on the incidence of hematoma formation and success rate.
- Trial name
- NCT01026649
- Testing
- Central venous catheterization
- Where
- South Korea
- Volunteers
- 334 people
- Sponsor
- Seoul National University Hospital
Retinal Hemorrhage, Bilateral, Retinal Hemorrhage, Left Eye
Retinal Imaging Study of Children That Might be at Risk of Having Retinal Hemorrhages
This is a clinical trial in which we will learn about the retinal findings in three clinical groups of children, who might be at risk of having retinal hemorrhages (RH).
- Conditions
- Retinal Hemorrhage, Bilateral, Retinal Hemorrhage, Left Eye, Retinal Hemorrhage, Right Eye
- Trial name
- RISC (NCT05576285)
- Testing
- ophthalmoscopy and fundus photography through dilated pupills
- Where
- Sweden
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Pregnancy Related, Diagnostic
Evaluation of the Performance of a Rapid Pregnancy Diagnostic Test.
The aim of the study is to evaluate the effectiveness of a rapid pregnancy diagnostic test to improve the medical care of patients in emergency room.
- Conditions
- Pregnancy Related, Diagnostic, Emergencies, Pelvic Pain
- Trial name
- NCT03250884
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Rennes University Hospital
Intracerebral Hemorrhage, Acute Ischemic Stroke
Biologic Mechanisms of Early Exercise After Intracerebral Hemorrhage
This study aims to determine whether in-bed cycle ergometry, early in the hospital course after a brain hemorrhage could balance damaging and reparative inflammation in the brain.
- Trial name
- BEACH (NCT04027049)
- Testing
- Supine cycle ergometry of the lower extremities
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Johns Hopkins University
Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis
Clinical Transcriptomics in Systemic Vasculitis (CUTIS)
Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.
- Conditions
- Cryoglobulinemic Vasculitis (CV), Drug-induced Vasculitis, Eosinophilic Granulomatosis With Polyangiitis (EGPA), IgA Vasculitis
- Trial name
- CUTIS (NCT03004326)
- Where
- 10 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- Peter Merkel
Menorrhagia
The Assessment of Tranexamic Acid in Women With Menorrhagia Who Have Bleeding Disorders
Many women have heavy periods and this can be associated with low blood, tiredness and inability to carry out normal activities. Approximately 10-30% of these women will have an underlying bleeding disorder.
- Trial name
- NCT00904709
- Testing
- tranexamic acid
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- K. Sue Robinson
Coronary Stenosis
EluNIR Ridaforolimus Eluting Coronary Stent System in Patients at High Bleeding Risk (HBR)- EluNIR HBR Study
The study will enroll approximately 316 subjects with a wide spectrum of PCI indications (stable angina as well as ACS), who are considered to be at high risk of bleeding.
- Trial name
- NCT03877848
- Testing
- Percutaneous Coronary Intervention (PCI)
- Where
- Israel
- Volunteers
- 319 people
- Sponsor
- Medinol Ltd.
Menorrhagia
Comparison of the Efficiency of Bipolar Energy Versus Monopolar Energy in Endometrial Ablation in Women Having Menorrhagia
Since the development a few years ago of bipolar energy in the surgery by operative hysteroscopy, the hysteroscopic treatment of menorrhagia by endometrial ablation can be achieved either by the use of monopolar or bipolar…
- Trial name
- NCT02642926
- Testing
- Monopolar current, Bipolar current
- Where
- France
- Volunteers
- 98 people
- Sponsor
- Brugmann University Hospital
Subarachnoid Hemorrhage
Evaluate the Use of Glibenclamide on Acute aSAH
A randomized, open-labeled, blank-controlled and prospective trial meant to evaluate the use of glibenclamide on acute aneurysmatic subarachnoid hemorrhage.
- Trial name
- NCT05137678
- Testing
- glibenclamide
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Beijing Tiantan Hospital
Bleeding Esophageal Varices
Endoscopic Injection Sclerotherapy Versus N-butyl-2-cyanoacrylate Injection
Endoscopic Injection Sclerotherapy vs N-butyl-2-cyanoacrylate Injection
- Trial name
- NCT03388125
- Testing
- Injection Sclerotherapy, N-butyl-2-cyanoacrylate
- Where
- Egypt
- Volunteers
- 113 people
- Sponsor
- Sherief Abd-Elsalam
Inguinal Hernia, Chronic Pain
3-point With 1-point Mesh Fixation in TAPP for Inguinal Hernia
This study was designed to compare the outcome of 3 point with 1 point lightweight mesh fixation in TAPP surgery for patients with inguinal hernia. The main outcome include seroma, chronic pain, recurrence, et al.
- Conditions
- Inguinal Hernia, Chronic Pain, Seroma, Recurrent
- Trial name
- NCT06314152
- Testing
- Lightweight mesh fixation in 3 points or 1 point
- Where
- China
- Volunteers
- 351 people
- Sponsor
- Nanchong Central Hospital
Immune Thrombocytopenia
The Efficacy and Safety of Huaiqihuang Granule in Children With Chronic Primary Immune Thrombocytopenia
This is a multisite, double-blind, randomized, placebo-controlled, and parallel study designed to evaluate the clinical efficacy and safety of Huaiqihuang granule for treatment to children with chronic primary immune…
- Trial name
- ITP (NCT03201848)
- Testing
- Huaiqihuang Granule
- Where
- 14 sites in China
- Volunteers
- 216 people
- Sponsor
- Qidong Gaitianli Medicines Co., Ltd
Blood Loss, Surgical, Blood Loss Anemia
Oral and Intravenous Tranexamic Acid in Lumbar Spine Surgery
The purpose of this project is to compare the effectiveness of two different but well accepted routes of administration of tranexamic acid in order to reduce blood loss and need for transfusion in patients undergoing lumbar spine…
- Trial name
- NCT03037515
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Total Laparoscopic Hysterectomy, Laparoscopic Supracervical Hysterectomy
Long Term Outcomes Following Total Laparoscopic Hysterectomy and Laparoscopic Supracervical Hysterectomy
Objective: To compare the occurrence and intensity of pelvic pain as well as patient satisfaction and quality of life after total laparoscopic and laparoscopic supracervical hysterectomy. Design: Prospective randomised trial.
- Conditions
- Total Laparoscopic Hysterectomy, Laparoscopic Supracervical Hysterectomy, Fibromas, Abnormal Uterine Bleeding
- Trial name
- NCT01289314
- Testing
- TLH, Laparoscopic supracervical hysterectomy
- Where
- Norway
- Volunteers
- 62 people
- Sponsor
- Oslo University Hospital
Fracture Humerus
Efficacy of Tranexamic Acid (TXA) in Humerus ORIF
The purpose of this study is to determine if administration of tranexamic acid (TXA), a clotting agent, will decrease blood loss, the need for transfusion, and reduce the likelihood of wound complications such as infection.
- Trial name
- TXA (NCT05802238)
- Testing
- Tranexamic acid (TXA), Saline
- Where
- United States
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Hemorrhagic Shock
Safety and Efficacy of PolyHeme(R) in Hemorrhagic Shock Following Traumatic Injuries Beginning in the Pre-Hospital Setting
This study is designed to assess the survival benefit of administering PolyHeme to severely injured trauma patients in hemorrhagic shock beginning in the prehospital setting, where blood is not available, and continuing…
- Trial name
- NCT00076648
- Testing
- Poly SFH-P Injection
- Where
- 32 sites in United States
- Sponsor
- Northfield Laboratories
Upper Gastrointestinal Bleeding
Single-use Versus Reusable Gastroscopes in Patients With Upper Gastrointestinal Bleeding.
Controlled-randomized trial evaluating single-use versus reusable gastroscopes in patients with upper gastrointestinal bleeding.
- Trial name
- OneScopeII (NCT06192355)
- Testing
- Endoscopic hemostasis using a Esophagogastroduodenoscopy
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University Hospital Augsburg
Abnormal Uterine Bleeding
The Role of TVSG and HS in Determining Endometrial Pathologies
Although hysteroscopy (HS) and transvaginal ultrasonography (TVSG) are methods in the diagnosis of AUB, there is some suspicion about their efficacy.
- Trial name
- NCT03441087
- Testing
- Transvaginal ultrasound, Hysteroscopy
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Hemorrhage, Postpartum
Haemorrhagia Postpartum: an Implementation Study on the NVOG Guidelines and MOET Instructions
The objectives of this study is first to asses to what extent the guidelines of the Dutch Society of Obstetrics and Gynaecology (NVOG) and the MOET (Management of Obstetric and Emergencies and Trauma) instructions for…
- Trial name
- Fluxim (NCT00928863)
- Testing
- implementation aids
- Where
- Netherlands
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- ZonMw: The Netherlands Organisation for Health Research and Development
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